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SRC [cytosol]
Stable Identifier
R-MMU-9628701
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
cytosol
Synonyms
P05480
Locations in the PathwayBrowser
Expand all
Signal Transduction (Mus musculus)
Signaling by GPCR (Mus musculus)
GPCR downstream signalling (Mus musculus)
G alpha (i) signalling events (Mus musculus)
G protein alpha (i)-SRC complex catalyzes SRC to p-Y419-SRC (Mus musculus)
G alpha (i):GTP:SRC-1 [plasma membrane] (Mus musculus)
SRC [cytosol] (Mus musculus)
External Reference Information
External Reference
UniProt:P05480 Src
Gene Names
Src
Chain
initiator methionine:, chain:2-535
Reference Genes
BioGPS Gene:20779 Src
KEGG:mmu:20779 Src
Monarch:20779 Src
NCBI Gene:20779 Src
UCSC:P05480 Src
Reference Transcript
RefSeq:NM_001025395.2 Src
RefSeq:NM_009271.3 Src
Other Identifiers
10477970
108711_at
1423240_at
1450918_s_at
17378721
20779
4447733
4505917
4804560
4812643
4829346
4885575
5034979
5043570
5059963
5091749
5135638
5152044
5256466
5258840
5282146
5302244
5305028
5374549
5400005
5430370
5495801
99388_at
A_51_P426214
A_52_P600547
GE33726
GO:0000122
GO:0001545
GO:0001819
GO:0002102
GO:0002376
GO:0003824
GO:0004672
GO:0004713
GO:0004715
GO:0005080
GO:0005102
GO:0005158
GO:0005178
GO:0005515
GO:0005524
GO:0005634
GO:0005654
GO:0005737
GO:0005739
GO:0005743
GO:0005764
GO:0005768
GO:0005770
GO:0005773
GO:0005829
GO:0005856
GO:0005884
GO:0005886
GO:0005901
GO:0005925
GO:0006355
GO:0006468
GO:0007010
GO:0007155
GO:0007173
GO:0007179
GO:0007229
GO:0007283
GO:0007611
GO:0008284
GO:0009410
GO:0009612
GO:0010447
GO:0010628
GO:0010629
GO:0010632
GO:0010634
GO:0010907
GO:0010954
GO:0014856
GO:0014911
GO:0016004
GO:0016020
GO:0016192
GO:0016301
GO:0016310
GO:0016477
GO:0016740
GO:0019899
GO:0019901
GO:0019904
GO:0020037
GO:0022407
GO:0022414
GO:0030054
GO:0030154
GO:0030331
GO:0030900
GO:0031333
GO:0031410
GO:0031648
GO:0031667
GO:0032205
GO:0032587
GO:0032869
GO:0033146
GO:0034139
GO:0034330
GO:0034332
GO:0034446
GO:0034614
GO:0035306
GO:0035331
GO:0035556
GO:0036035
GO:0036120
GO:0038166
GO:0042169
GO:0042476
GO:0042542
GO:0043025
GO:0043065
GO:0043066
GO:0043149
GO:0043226
GO:0043274
GO:0044294
GO:0044325
GO:0044877
GO:0045056
GO:0045087
GO:0045453
GO:0045747
GO:0045780
GO:0045785
GO:0045821
GO:0046579
GO:0046628
GO:0046875
GO:0048008
GO:0048011
GO:0048041
GO:0048471
GO:0048477
GO:0048856
GO:0048870
GO:0050731
GO:0050839
GO:0050847
GO:0050877
GO:0051057
GO:0051219
GO:0051222
GO:0051385
GO:0051450
GO:0051602
GO:0051895
GO:0051897
GO:0051902
GO:0060065
GO:0060444
GO:0060491
GO:0060576
GO:0070102
GO:0070161
GO:0070301
GO:0070374
GO:0070542
GO:0070555
GO:0070700
GO:0071222
GO:0071253
GO:0071375
GO:0071393
GO:0071398
GO:0071456
GO:0071498
GO:0071560
GO:0071803
GO:0071897
GO:0086091
GO:0090263
GO:0097060
GO:0097110
GO:0098542
GO:0098609
GO:0098772
GO:0098978
GO:0099091
GO:0140096
GO:1900182
GO:1902533
GO:1902737
GO:1904263
GO:1904385
GO:1904707
GO:1990646
GO:2000256
GO:2000386
GO:2000394
GO:2000588
GO:2000641
GO:2000811
GO:2001237
GO:2001243
GO:2001286
ILMN_1254757
ILMN_2638454
ILMN_2638455
ILMN_2677529
ILMN_3148543
Msa.1184.0_at
mMC016824
mMR030435
Participates
as a component of
G alpha (i):GTP:SRC-1 [plasma membrane] (Mus musculus)
Other forms of this molecule
SRC-2 [cytosol]
phospho-MyrG-p-Y419-SRC [plasma membrane]
SRC-1 [plasma membrane]
phospho-MyrG,p-Y530-SRC [plasma membrane]
phospho-p-Y419-SRC [cytosol]
Src [cytosol]
phospho-p-Y419-SRC-1 [plasma membrane]
MyrG-SRC [plasma membrane]
phospho-p-Y419-SRC [cytosol]
MyrG-p-Y424-Src [plasma membrane]
Activated Src [nucleoplasm]
p-Y416-Src [cytosol]
Inferred From
SRC [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_001020566.1
,
NP_033297.2
ENSEMBL
ENSMUSP00000090237
,
ENSMUST00000109533
,
ENSMUST00000029175
,
ENSMUST00000092576
,
ENSMUSP00000105155
,
ENSMUSP00000105157
,
ENSMUST00000109529
,
ENSMUSP00000029175
,
ENSMUST00000109531
,
ENSMUSP00000105159
ZINC - Substances
SRC_MOUSE
ZINC target
P05480
PRO
P05480
MGI
98397
ZINC - Predictions - Purchasable
SRC_MOUSE
GlyGen
P05480
PDB
6F3F
,
8XN8
Interactors (18)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q05397 PTK2
11
p-6Y-PTK2 [cytosol]
(R-HSA-354128)
p-Y397-PTK2 [cytosol]
(R-HSA-354068)
PTK2 [cytosol]
(R-HSA-201621)
PTK2(1-772) [cytosol]
(R-HSA-202827)
PTK2(773-1052) [cytosol]
(R-HSA-202829)
p-5Y-PTK2 [cytosol]
(R-HSA-5218711)
p-5Y,S732-PTK2 [cytosol]
(R-HSA-5229006)
p-6Y,S732-PTK2 [cytosol]
(R-HSA-5218694)
pY-PTK2 [cytosol]
(R-HSA-9632393)
p-Y194,Y397-PTK2 [cytosol]
(R-HSA-8874600)
p-Y194,Y397,Y576,Y577-PTK2 [cytosol]
(R-HSA-8874613)
0.683
5
UniProt:P31016 Dlg4
3
Dlg4 [plasma membrane]
(R-RNO-9612601)
Dlg4 [endocytic vesicle membrane]
(R-RNO-416847)
Dlg4 [cytosol]
(R-RNO-6794248)
0.645
9
UniProt:P19367 HK1
4
HK1 [cytosol]
(R-HSA-70395)
HK1 L529S [cytosol]
(R-HSA-5621861)
HK1 H577_C672del [cytosol]
(R-HSA-5621873)
HK1 T680S [cytosol]
(R-HSA-5621880)
0.644
8
UniProt:Q13507-3 TRPC3
0.602
4
UniProt:P52789 HK2
1
HK2 [cytosol]
(R-HSA-70378)
0.602
4
UniProt:P34152 Ptk2
13
phospho-p-Y194,Y397,Y576,Y577-PTK2 [cytosol]
(R-MMU-8874613)
phospho-p-Y194,Y397-PTK2 [cytosol]
(R-MMU-8874600)
phospho-pY-PTK2 [cytosol]
(R-MMU-9632393)
p-Y428-FAK1 [cytosol]
(R-MMU-3928397)
Fak1 [cytosol]
(R-MMU-3928448)
phospho-p-6Y,S732-PTK2 [cytosol]
(R-MMU-5218694)
phospho-p-5Y,S732-PTK2 [cytosol]
(R-MMU-5229006)
phospho-p-5Y-PTK2 [cytosol]
(R-MMU-5218711)
PTK2(773-1052) [cytosol]
(R-MMU-202829)
PTK2(1-772) [cytosol]
(R-MMU-202827)
PTK2 [cytosol]
(R-MMU-201621)
phospho-p-Y397-PTK2 [cytosol]
(R-MMU-354068)
phospho-p-6Y-PTK2 [cytosol]
(R-MMU-354128)
0.589
2
UniProt:Q00959 Grin2a
3
Grin2a [plasma membrane]
(R-RNO-6794271)
Grin2a [endoplasmic reticulum membrane]
(R-RNO-9609845)
p-Y-Grin2a [plasma membrane]
(R-RNO-9628245)
0.558
4
UniProt:Q01973 ROR1
2
ROR1 [clathrin-coated endocytic vesicle membrane]
(R-HSA-5140727)
ROR1 [plasma membrane]
(R-HSA-197814)
0.544
2
UniProt:Q9CQV6
3
Map1lc3b [autophagosome membrane]
(R-MMU-5683641)
Map1lc3b [cytosol]
(R-MMU-5682674)
Map1lc3b [cytosol]
(R-MMU-5205651)
0.528
2
UniProt:O70469
1
Dok2 [cytosol]
(R-MMU-204823)
0.524
3
UniProt:P70315 Was
1
Wasp [cytosol]
(R-MMU-2029026)
0.524
2
UniProt:P07141 Csf1
4
Csf1 [extracellular region]
(R-MMU-9680617)
Csf1 [extracellular region]
(R-MMU-9009484)
phospho-Csf1 [endoplasmic reticulum lumen]
(R-MMU-8956881)
Csf1 [endoplasmic reticulum lumen]
(R-MMU-8956778)
0.524
2
UniProt:P23242 Gja1
7
p-S373-Gja1 [plasma membrane]
(R-MMU-9857672)
Gja1 [Golgi membrane]
(R-MMU-190649)
Gja1 [endoplasmic reticulum membrane]
(R-MMU-190654)
Gja1 [lysosomal membrane]
(R-MMU-196173)
phospho-Gja1 [plasma membrane]
(R-MMU-191657)
Gja1 [plasma membrane]
(R-MMU-9857668)
Gja1 [Golgi-associated vesicle membrane]
(R-MMU-190544)
0.499
3
UniProt:P31750 Akt1
12
phospho-p-T308,S473-AKT1 [nucleoplasm]
(R-MMU-198357)
phospho-p-T308,S473-AKT1 [cytosol]
(R-MMU-198356)
phospho-p-S473-AKT1 [plasma membrane]
(R-MMU-377265)
AKT1 [plasma membrane]
(R-MMU-199416)
AKT1 [cytosol]
(R-MMU-58252)
phospho-p-T308-AKT1 [cytosol]
(R-MMU-198634)
phospho-p-Y315,Y326-AKT1 [cytosol]
(R-MMU-8848757)
phospho-p-T308,S473-AKT1 [plasma membrane]
(R-MMU-199430)
p-T308,S473-Akt1 [cytosol]
(R-MMU-162346)
Akt1 [cytosol]
(R-MMU-189709)
phospho-p-S473-AKT1 [cytosol]
(R-MMU-9841264)
p-T308,S473-Akt1 [plasma membrane]
(R-MMU-1445123)
0.499
3
UniProt:Q63767
4
phospho-Bcar1 [cytosol]
(R-RNO-372645)
phospho-Bcar1 [cytosol]
(R-RNO-5218739)
phospho-Bcar1 [cytosol]
(R-RNO-8848723)
Bcar1 [cytosol]
(R-RNO-201625)
0.471
2
UniProt:P54763 Ephb2
9
phospho-p-Y596,Y602-EPHB2 [plasma membrane]
(R-MMU-3928375)
p-Ephb2 [plasma membrane]
(R-MMU-3928433)
EPHB2 [plasma membrane]
(R-MMU-443809)
EPHB2 (19-?) [extracellular region]
(R-MMU-3928436)
EPHB2 (?-1055) [plasma membrane]
(R-MMU-3928386)
EPHB2 (?-1055) [cytosol]
(R-MMU-3928432)
P54763 [plasma membrane]
(R-MMU-3928394)
Ephb2 [plasma membrane]
(R-MMU-3928443)
p-Y604,Y610-Ephb2 [plasma membrane]
(R-MMU-4093312)
0.463
3
UniProt:P35546 Ret
3
Ret [plasma membrane]
(R-MMU-9830456)
RET [plasma membrane]
(R-MMU-8853797)
phospho-p-5Y-RET [plasma membrane]
(R-MMU-8854162)
0.463
2
UniProt:P35438 Grin1
3
Grin1 [plasma membrane]
(R-MMU-3928395)
Grin1 [endoplasmic reticulum membrane]
(R-MMU-9610359)
Grin1 [transport vesicle membrane]
(R-MMU-9610566)
0.462
2
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