Expression of Asns

Stable Identifier
R-MMU-9644315
Type
Reaction [omitted]
Species
Mus musculus
Compartment
nucleoplasm, cytosol
ReviewStatus
5/5
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Expression of Asns
The Asns gene is transcribed to yield mRNA and the mRNA is translated to yield protein (Huggins et al. 2015). Expression of Asns is increased in response to amino acid deficiency (Huggins et al. 2015) and heme deficiency (Zhang et al. 2019).
Literature References
PubMed ID Title Journal Year
31033440 HRI coordinates translation necessary for protein homeostasis and mitochondrial function in erythropoiesis

Macias-Garcia, A, Zhang, S, Butty, VL, Levine, SS, Sankaran, VG, Velazquez, J, Ulirsch, JC, Chen, JJ

Elife 2019
26667036 C/EBPγ Is a Critical Regulator of Cellular Stress Response Networks through Heterodimerization with ATF4

Haines, DC, Jailwala, P, Saylor, KL, Huggins, CJ, Quiñones, OA, Johnson, PF, Martin, N, Kasoji, M, Gonit, M, Mayekar, MK

Mol. Cell. Biol. 2015
Participants
Input
Output
This event is regulated
Positively by
Regulator
Atf4:Cebpg:Asns gene [nucleoplasm] (Mus musculus)
Orthologous Events
Expression of ASNS (Asparagine Synthetase) (Homo sapiens)
Authored
May, B  (2019-04-12)
Reviewed
Staschke, KA  (2019-11-20)
Chen, JJ  (2019-10-22)
Bruhat, A  (2019-09-15)
Created
May, B  (2019-04-12)
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