Hdac6 binds microtubule

Stable Identifier
R-MMU-9646393
Type
Reaction [binding]
Species
Mus musculus
Compartment
cytosol
ReviewStatus
5/5
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Hdac6 binds microtubule
Histone deacetylase 6 (Hdac6) binds to microtubules and can anchor misfolded proteins and dynein motor to the microtubule (Hubbert C et al. 2002). Following this, the dynein motors traverse the microtubule to reach the microtubule-organizing center (MTOC).
Literature References
PubMed ID Title Journal Year
12024216 HDAC6 is a microtubule-associated deacetylase

Nixon, A, Wang, XF, Yoshida, M, Shao, R, Guardiola, A, Hubbert, C, Yao, TP, Ito, A, Kawaguchi, Y

Nature 2002
Participants
Input
Output
Orthologous Events
Misfolded proteins:HDAC6:Dynein motor binds microtubule (Homo sapiens)
Authored
Varusai, TM  (2019-05-23)
Reviewed
Metzakopian, E  (2019-05-24)
Created
Varusai, TM  (2019-05-23)
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