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About
What is Reactome ?
News
Team
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Our Logo
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Digital Preservation
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S-Farn-Me KRAS4B [plasma membrane]
Stable Identifier
R-MMU-9647815
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
plasma membrane
Synonyms
P32883
Locations in the PathwayBrowser
Expand all
Developmental Biology (Mus musculus)
Nervous system development (Mus musculus)
Axon guidance (Mus musculus)
NCAM signaling for neurite out-growth (Mus musculus)
NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras (Mus musculus)
p21 RAS:GDP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
p21 RAS:GTP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
Hemostasis (Mus musculus)
Cell surface interactions at the vascular wall (Mus musculus)
Tie2 Signaling (Mus musculus)
Sos-mediated nucleotide exchange of Ras (Tie2 receptor:Grb2:Sos) (Mus musculus)
p21 RAS:GDP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
p21 RAS:GTP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
Immune System (Mus musculus)
Adaptive Immune System (Mus musculus)
Signaling by the B Cell Receptor (BCR) (Mus musculus)
Downstream signaling events of B Cell Receptor (BCR) (Mus musculus)
Activation of RAS in B cells (Mus musculus)
p-RasGRP1,3:DAG cause RAS to exchange GDP for GTP (Mus musculus)
p21 RAS:GDP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
p21 RAS:GTP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
Cytokine Signaling in Immune system (Mus musculus)
FLT3 Signaling (Mus musculus)
SOS1-mediated nucleotide exchange of RAS downstream of FLT3 (Mus musculus)
p21 RAS:GDP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
p21 RAS:GTP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
Innate Immune System (Mus musculus)
C-type lectin receptors (CLRs) (Mus musculus)
CD209 (DC-SIGN) signaling (Mus musculus)
PAK phosphorylates p21 RAF1 on S338 (Mus musculus)
p21 RAS:GTP:RAF1 [plasma membrane] (Mus musculus)
p21 RAS:GTP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
p21 RAS:GTP:p-S338-RAF1 [plasma membrane] (Mus musculus)
p21 RAS:GTP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
RAF1 binds p21 RAS:GTP (Mus musculus)
p21 RAS:GTP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
p21 RAS:GTP:RAF1 [plasma membrane] (Mus musculus)
p21 RAS:GTP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
SFKs phosphorylates RAF1 on Y340,Y341 (Mus musculus)
p21 RAS:GTP:p-S338,Y340,Y341-RAF1 [plasma membrane] (Mus musculus)
p21 RAS:GTP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
p21 RAS:GTP:p-S338-RAF1 [plasma membrane] (Mus musculus)
p21 RAS:GTP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
DAP12 interactions (Mus musculus)
DAP12 signaling (Mus musculus)
SOS mediated nucleotide exchange of RAS (SHC) (Mus musculus)
p21 RAS:GDP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
p21 RAS:GTP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
Fc epsilon receptor (FCERI) signaling (Mus musculus)
FCERI mediated MAPK activation (Mus musculus)
SOS mediated nucleotide exchange of RAS (SHC) (Mus musculus)
p21 RAS:GDP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
p21 RAS:GTP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
Signal Transduction (Mus musculus)
MAPK family signaling cascades (Mus musculus)
MAPK1/MAPK3 signaling (Mus musculus)
RAF/MAP kinase cascade (Mus musculus)
Intrinsic nucleotide exchange on RAS (Mus musculus)
p21 RAS:GDP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
p21 RAS:GTP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
MAP2K and MAPK activation (Mus musculus)
Dissociation of RAS:RAF complex (Mus musculus)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Mus musculus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Mus musculus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Mus musculus)
p21 RAS:GTP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
p21RAS:GTP:activated RAF homo/heterodimers [plasma membrane] (Mus musculus)
p21 RAS:GTP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
Dual mechanism MAP2K inhibitors bind MAP2Ks (Mus musculus)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Mus musculus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Mus musculus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Mus musculus)
p21 RAS:GTP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Mus musculus)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Mus musculus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Mus musculus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Mus musculus)
p21 RAS:GTP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
Dual mechanism MAPK inhibitors bind MAPKs (Mus musculus)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Mus musculus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Mus musculus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Mus musculus)
p21 RAS:GTP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
activated RAF:scaffold:p-2S MAP2K:MAPK:dual mechanism MAPK inhibitors [plasma membrane] (Mus musculus)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Mus musculus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Mus musculus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Mus musculus)
p21 RAS:GTP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
MAP2Ks and MAPKs bind to the activated RAF complex (Mus musculus)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Mus musculus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Mus musculus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Mus musculus)
p21 RAS:GTP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Mus musculus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Mus musculus)
p21 RAS:GTP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
p21 RAS:GTP:activated RAF1 homo/heterodimer:PEBP1 [plasma membrane] (Mus musculus)
p21RAS:GTP:activated RAF1 homo/heterodimer [plasma membrane] (Mus musculus)
p21 RAS:GTP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
MAP2Ks phosphorylate MAPKs (Mus musculus)
activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Mus musculus)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Mus musculus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Mus musculus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Mus musculus)
p21 RAS:GTP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
activated RAF:scaffold:p-2S MAP2K:MAPK:single mechanism MAP2K inhibitors [plasma membrane] (Mus musculus)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Mus musculus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Mus musculus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Mus musculus)
p21 RAS:GTP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Mus musculus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Mus musculus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Mus musculus)
p21 RAS:GTP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
activated RAF:scaffold:p-2S MAP2K:MAPK:dual mechanism MAPK inhibitors [plasma membrane] (Mus musculus)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Mus musculus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Mus musculus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Mus musculus)
p21 RAS:GTP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Mus musculus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Mus musculus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Mus musculus)
p21 RAS:GTP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
RAF phosphorylates MAP2K dimer (Mus musculus)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Mus musculus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Mus musculus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Mus musculus)
p21 RAS:GTP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Mus musculus)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Mus musculus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Mus musculus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Mus musculus)
p21 RAS:GTP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Mus musculus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Mus musculus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Mus musculus)
p21 RAS:GTP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
p21RAS:GTP:homo/heterodimerized RAF complex:RAF dimer inhibitors [plasma membrane] (Mus musculus)
p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] (Mus musculus)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Mus musculus)
p21 RAS:GTP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks (Mus musculus)
activated RAF:scaffold:p-2S MAP2K:MAPK:single mechanism MAP2K inhibitors [plasma membrane] (Mus musculus)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Mus musculus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Mus musculus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Mus musculus)
p21 RAS:GTP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Mus musculus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Mus musculus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Mus musculus)
p21 RAS:GTP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
Single mechanism MAPK inhibitors bind phosphorylated MAPK (Mus musculus)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Mus musculus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Mus musculus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Mus musculus)
p21 RAS:GTP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK:single mechanism MAPK inhibitors [plasma membrane] (Mus musculus)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Mus musculus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Mus musculus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Mus musculus)
p21 RAS:GTP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
Negative regulation of MAPK pathway (Mus musculus)
BRAP autoubiquitinates (Mus musculus)
p21 RAS:GTP:BRAP [plasma membrane] (Mus musculus)
p21 RAS:GTP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
p21 RAS:GTP:ub-BRAP [plasma membrane] (Mus musculus)
p21 RAS:GTP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
BRAP binds RAS:GTP (Mus musculus)
p21 RAS:GTP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
p21 RAS:GTP:BRAP [plasma membrane] (Mus musculus)
p21 RAS:GTP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
PEBP1 binds activated RAF1 (Mus musculus)
p21 RAS:GTP:activated RAF1 homo/heterodimer:PEBP1 [plasma membrane] (Mus musculus)
p21RAS:GTP:activated RAF1 homo/heterodimer [plasma membrane] (Mus musculus)
p21 RAS:GTP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
p21RAS:GTP:activated RAF1 homo/heterodimer [plasma membrane] (Mus musculus)
p21 RAS:GTP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
PP2A dephosphorylates RAF1 (Mus musculus)
p21RAS:GTP:dephosphorylated RAF1 homo/heterodimer [plasma membrane] (Mus musculus)
p21 RAS:GTP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
p21RAS:GTP:p-S621 RAF1 homo/heterodimer [plasma membrane] (Mus musculus)
p21 RAS:GTP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
PP5 dephosphorylates RAF1 S338 (Mus musculus)
p21RAS:GTP:activated RAF1 homo/heterodimer [plasma membrane] (Mus musculus)
p21 RAS:GTP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
p21RAS:GTP:dephosphorylated RAF1 homo/heterodimer [plasma membrane] (Mus musculus)
p21 RAS:GTP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
RAF activation (Mus musculus)
"Activator" RAF:YWHAB dimer binds RAS:GTP (Mus musculus)
p21 RAS:GTP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Mus musculus)
p21 RAS:GTP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
Phosphorylation of RAF (Mus musculus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Mus musculus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Mus musculus)
p21 RAS:GTP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] (Mus musculus)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Mus musculus)
p21 RAS:GTP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
RAS:GTP:'activator' RAF homo/heterodimerizes with other RAF monomers (Mus musculus)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Mus musculus)
p21 RAS:GTP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] (Mus musculus)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Mus musculus)
p21 RAS:GTP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
Raf dimer inhibitors bind RAF heterodimers (Mus musculus)
p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] (Mus musculus)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Mus musculus)
p21 RAS:GTP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
p21RAS:GTP:homo/heterodimerized RAF complex:RAF dimer inhibitors [plasma membrane] (Mus musculus)
p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] (Mus musculus)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Mus musculus)
p21 RAS:GTP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
RAS GEFs promote RAS nucleotide exchange (Mus musculus)
p21 RAS:GDP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
p21 RAS:GTP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
RAS intrinsic GTPase activity hydrolyzes GTP to GDP (Mus musculus)
p21 RAS:GDP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
p21 RAS:GTP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
RAS processing (Mus musculus)
Calmodulin dissociates KRAS4B from the plasma membrane (Mus musculus)
S-Farn-Me KRAS4B:CALM1:4xCa2+ [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
KRAS4B is phosphorylated on serine 181 (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
KRAS4B recycles to the plasma membrane (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
Mature S-Farn-Me KRAS4B translocates to plasma membrane (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B binds calmodulin (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B:CALM1:4xCa2+ [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
mature p21 RAS binds GDP (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
p21 RAS:GDP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
RAS:GTP binds PI3K (Mus musculus)
p21 RAS:GTP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
p21 RAS:GTP:PI3K [plasma membrane] (Mus musculus)
p21 RAS:GTP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
Regulation of RAS by GAPs (Mus musculus)
RAS GAPs bind RAS:GTP (Mus musculus)
p21 RAS:GTP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
p21 RAS:GTP:RAS GAPs [plasma membrane] (Mus musculus)
p21 RAS:GTP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
RAS GAPs stimulate RAS GTPase activity (Mus musculus)
p21 RAS:GDP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
p21 RAS:GTP:RAS GAPs [plasma membrane] (Mus musculus)
p21 RAS:GTP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
Signaling by GPCR (Mus musculus)
GPCR downstream signalling (Mus musculus)
G alpha (q) signalling events (Mus musculus)
Gastrin-CREB signalling pathway via PKC and MAPK (Mus musculus)
EGFR Transactivation by Gastrin (Mus musculus)
SOS1-mediated nucleotide exchange of RAS (HB-EFG-initiated) (Mus musculus)
p21 RAS:GDP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
p21 RAS:GTP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
Signaling by Non-Receptor Tyrosine Kinases (Mus musculus)
Signaling by PTK6 (Mus musculus)
PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases (Mus musculus)
RASA1 binds RAS:GTP (Mus musculus)
p21 RAS:GTP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
p21 RAS:GTP:RASA1 [plasma membrane] (Mus musculus)
p21 RAS:GTP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
RASA1 stimulates RAS GTPase activity (Mus musculus)
p21 RAS:GDP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
p21 RAS:GTP:RASA1 [plasma membrane] (Mus musculus)
p21 RAS:GTP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
Signaling by Nuclear Receptors (Mus musculus)
ESR-mediated signaling (Mus musculus)
Extra-nuclear estrogen signaling (Mus musculus)
Estrogen-stimulated signaling through PRKCZ (Mus musculus)
ESR1- and PRCKZ-dependent MAPK1 translocation to the nucleus (Mus musculus)
PDPK1:PIP3:pS, p-T410 PRKCZ:p21 RAS:GTP [plasma membrane] (Mus musculus)
p21 RAS:GTP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
PRKCZ recruits RAS in response to estrogen stimulation (Mus musculus)
PDPK1:PIP3:pS, p-T410 PRKCZ:p21 RAS:GDP [plasma membrane] (Mus musculus)
p21 RAS:GDP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
p21 RAS:GDP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
PRKCZ stimulates RAS nucleotide exchange in response to estrogen (Mus musculus)
PDPK1:PIP3:pS, p-T410 PRKCZ:p21 RAS:GDP [plasma membrane] (Mus musculus)
p21 RAS:GDP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
PDPK1:PIP3:pS, p-T410 PRKCZ:p21 RAS:GTP [plasma membrane] (Mus musculus)
p21 RAS:GTP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
Signaling by Receptor Tyrosine Kinases (Mus musculus)
Signaling by EGFR (Mus musculus)
GRB2 events in EGFR signaling (Mus musculus)
SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1) (Mus musculus)
p21 RAS:GDP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
p21 RAS:GTP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
SHC1 events in EGFR signaling (Mus musculus)
SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1) (Mus musculus)
p21 RAS:GDP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
p21 RAS:GTP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
Signaling by ERBB2 (Mus musculus)
GRB2 events in ERBB2 signaling (Mus musculus)
RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers (Mus musculus)
p21 RAS:GDP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
p21 RAS:GTP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
Signaling by ERBB4 (Mus musculus)
SHC1 events in ERBB4 signaling (Mus musculus)
RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349,350-SHC1:p-ERBB4 (Mus musculus)
p21 RAS:GDP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
p21 RAS:GTP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
Signaling by FGFR (Mus musculus)
Signaling by FGFR1 (Mus musculus)
Downstream signaling of activated FGFR1 (Mus musculus)
FRS-mediated FGFR1 signaling (Mus musculus)
Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange (Mus musculus)
p21 RAS:GDP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
p21 RAS:GTP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
Activated FGFR1:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Mus musculus)
p21 RAS:GDP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
p21 RAS:GTP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
SHC-mediated cascade:FGFR1 (Mus musculus)
Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Mus musculus)
p21 RAS:GDP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
p21 RAS:GTP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
Signaling by FGFR2 (Mus musculus)
Downstream signaling of activated FGFR2 (Mus musculus)
FRS-mediated FGFR2 signaling (Mus musculus)
Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Mus musculus)
p21 RAS:GDP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
p21 RAS:GTP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
Activated FGFR2:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Mus musculus)
p21 RAS:GDP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
p21 RAS:GTP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
SHC-mediated cascade:FGFR2 (Mus musculus)
Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Mus musculus)
p21 RAS:GDP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
p21 RAS:GTP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
Signaling by FGFR3 (Mus musculus)
Downstream signaling of activated FGFR3 (Mus musculus)
FRS-mediated FGFR3 signaling (Mus musculus)
Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Mus musculus)
p21 RAS:GDP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
p21 RAS:GTP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
Activated FGFR3:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Mus musculus)
p21 RAS:GDP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
p21 RAS:GTP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
SHC-mediated cascade:FGFR3 (Mus musculus)
Activated FGFR3:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Mus musculus)
p21 RAS:GDP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
p21 RAS:GTP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
Signaling by FGFR4 (Mus musculus)
Downstream signaling of activated FGFR4 (Mus musculus)
FRS-mediated FGFR4 signaling (Mus musculus)
Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Mus musculus)
p21 RAS:GDP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
p21 RAS:GTP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
Activated FGFR4:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Mus musculus)
p21 RAS:GDP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
p21 RAS:GTP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
SHC-mediated cascade:FGFR4 (Mus musculus)
Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Mus musculus)
p21 RAS:GDP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
p21 RAS:GTP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
Signaling by MET (Mus musculus)
MET activates RAS signaling (Mus musculus)
RAS guanyl nucleotide exchange by MET-bound GRB2:SOS1 (Mus musculus)
p21 RAS:GDP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
p21 RAS:GTP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
RAS guanyl nucleotide exchange by SOS1 associated with RANBP9 and MET (Mus musculus)
p21 RAS:GDP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
p21 RAS:GTP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
RAS guanyl nucleotide exchange by SOS1 bound to GRB2, SCH1-2 and MET (Mus musculus)
p21 RAS:GDP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
p21 RAS:GTP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
Signaling by NTRKs (Mus musculus)
Signaling by NTRK1 (TRKA) (Mus musculus)
Signalling to ERKs (Mus musculus)
Signalling to RAS (Mus musculus)
p38MAPK events (Mus musculus)
Ral-GDS binds to Ras-GTP (Mus musculus)
Ras-GTP:RalGDS complex [plasma membrane] (Mus musculus)
p21 RAS:GTP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
p21 RAS:GTP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
Signaling by PDGF (Mus musculus)
Downstream signal transduction (Mus musculus)
SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS) (Mus musculus)
p21 RAS:GDP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
p21 RAS:GTP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
Signaling by SCF-KIT (Mus musculus)
Activation of RAS by p-KIT bound SOS1 (Mus musculus)
p21 RAS:GDP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
p21 RAS:GTP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
Signaling by VEGF (Mus musculus)
VEGFA-VEGFR2 Pathway (Mus musculus)
VEGFR2 mediated cell proliferation (Mus musculus)
p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate (Mus musculus)
RASA1:p21 RAS:GTP:SPG [plasma membrane] (Mus musculus)
p21 RAS:GTP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
p21 RAS:GTP [plasma membrane] (Mus musculus)
mature p21 RAS [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
Signaling by WNT (Mus musculus)
Beta-catenin independent WNT signaling (Mus musculus)
Ca2+ pathway (Mus musculus)
Active calmodulin binds CAMK2 (Mus musculus)
S-Farn-Me KRAS4B:CALM1:4xCa2+ [plasma membrane] (Mus musculus)
S-Farn-Me KRAS4B [plasma membrane] (Mus musculus)
External Reference Information
External Reference
UniProt:P32883 Kras
Gene Names
Kras, Kras2
Chain
chain:1-186, initiator methionine:, chain:2-186, propeptide:187-189
Reference Genes
BioGPS Gene:16653 Kras
KEGG:mmu:16653 Kras
Monarch:16653 Kras
NCBI Gene:16653 Kras
UCSC:P32883 Kras
Reference Transcript
RefSeq:XM_006506918.3 Kras
RefSeq:NM_021284.6 Kras
Other Identifiers
10549256
106672_at
106938_at
1426229_s_at
1434000_at
1441442_at
1451979_at
16653
17472725
4313059
4335609
4412753
4441411
4489978
4570800
4607066
4802038
4827993
4926216
5193962
5260598
5311146
5431855
5473122
97991_at
A_51_P136233
A_51_P377237
A_51_P509489
A_55_P2008591
GE32892
GO:0000166
GO:0003824
GO:0003924
GO:0003925
GO:0005515
GO:0005525
GO:0005737
GO:0005886
GO:0007010
GO:0007165
GO:0007265
GO:0008283
GO:0008542
GO:0009898
GO:0010467
GO:0010628
GO:0012501
GO:0012505
GO:0014009
GO:0016020
GO:0016601
GO:0016787
GO:0019002
GO:0019003
GO:0019221
GO:0021897
GO:0030036
GO:0030154
GO:0030275
GO:0030857
GO:0032228
GO:0035022
GO:0035914
GO:0043495
GO:0043524
GO:0044877
GO:0048009
GO:0048169
GO:0048856
GO:0048873
GO:0050877
GO:0051146
GO:0051402
GO:0060090
GO:0060252
GO:0060441
GO:0060509
GO:0098772
GO:2000774
ILMN_2773211
mMC023531
Participates
as an output of
KRAS4B recycles to the plasma membrane (Mus musculus)
Mature S-Farn-Me KRAS4B translocates to plasma membrane (Mus musculus)
as an input of
KRAS4B is phosphorylated on serine 181 (Mus musculus)
S-Farn-Me KRAS4B binds calmodulin (Mus musculus)
as a component of
S-Farn-Me KRAS4B:CALM1:4xCa2+ [plasma membrane] (Mus musculus)
as a member of
mature p21 RAS [plasma membrane] (Mus musculus)
Other forms of this molecule
phospho-p-Y32-S-Farn-Me-PalmS KRAS [plasma membrane]
Kras [plasma membrane]
phospho-pS181-S-Farn-Me KRAS4B [mitochondrial outer membrane]
S-Farn-Me KRAS4A [plasma membrane]
S-Farn-Me PalmS KRAS4A [Golgi membrane]
proKRAS [cytosol]
pro-KRAS4A [cytosol]
S-Farn proKRAS4B [endoplasmic reticulum membrane]
S-Farn-proKRAS [endoplasmic reticulum membrane]
S-Farn-Me KRAS [endoplasmic reticulum membrane]
S-Farn KRAS4B [endoplasmic reticulum membrane]
S-Farn-KRAS [endoplasmic reticulum membrane]
S-Farn-Me KRAS4B [endoplasmic reticulum membrane]
phospho-pS181-S-Farn-Me KRAS4B [plasma membrane]
S-Farn-Me KRAS4B [cytosol]
S-Farn-Me-PalmS KRAS4A [plasma membrane]
Inferred From
S-Farn-Me KRAS4B [plasma membrane]
(Homo sapiens)
Modified Residues
Name
S-farnesyl-L-cysteine methyl ester at 185 (in Homo sapiens)
Coordinate
185
PsiMod Name
S-farnesyl-L-cysteine methyl ester
PsiMod Definition
A protein modification that effectively converts an L-cysteine residue to S-farnesyl-L-cysteine methyl ester.
Cross References
RefSeq
NP_067259.4
,
XP_006506981.1
ENSEMBL
ENSMUST00000032399
,
ENSMUSP00000107339
,
ENSMUSP00000032399
,
ENSMUST00000111710
PRO
P32883
GlyGen
P32883
MGI
96680
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P04049 RAF1
20
p-S338,Y340,Y341-RAF1 [cytosol]
(R-HSA-5624465)
p-S338-RAF1 [cytosol]
(R-HSA-5624469)
p-S621-RAF1 S259F [cytosol]
(R-HSA-9656124)
p-S621-RAF1 S257L [cytosol]
(R-HSA-9656121)
p-S621-RAF1 P261L [cytosol]
(R-HSA-9656106)
p-S621-RAF1 N262K [cytosol]
(R-HSA-9656101)
p-S621-RAF1 P261A [cytosol]
(R-HSA-9656103)
p-S621-RAF1 P261S [cytosol]
(R-HSA-9656113)
p-S621-RAF1 S259T [cytosol]
(R-HSA-9656130)
p-S621-RAF1 P261T [cytosol]
(R-HSA-9656115)
p-S621-RAF1 P261R [cytosol]
(R-HSA-9656110)
p-S621-RAF1 S259P [cytosol]
(R-HSA-9656127)
p-S621-RAF1 T260I [cytosol]
(R-HSA-9656136)
p-S621-RAF1 T260R [cytosol]
(R-HSA-9656139)
p-S621-RAF1 V263A [cytosol]
(R-HSA-9656148)
p-S621-RAF1 R256S [cytosol]
(R-HSA-9656119)
p-S621-RAF1 T491I [cytosol]
(R-HSA-9656143)
p-S621-RAF1 D486N [cytosol]
(R-HSA-9656088)
p-S621-RAF1 S427G [cytosol]
(R-HSA-9656134)
p-S621-RAF1 L613V [cytosol]
(R-HSA-9656098)
0.573
2
UniProt:Q01279
6
phospho-p-6Y-EGFR [clathrin-coated endocytic vesicle membrane]
(R-MMU-8869138)
phospho-p-4Y-EGFR [plasma membrane]
(R-MMU-180287)
phospho-p-Y1016,Y1069,Y1092,Y1110,Y1197-EGFR [plasma membrane]
(R-MMU-8864019)
EGFR [plasma membrane]
(R-MMU-179837)
phospho-p-Y1086,Y1101-EGFR [plasma membrane]
(R-MMU-179868)
phospho-p-6Y-EGFR [plasma membrane]
(R-MMU-179803)
0.463
3
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