Outer hair cell stereocilium cytoskeleton [cytosol]

Stable Identifier
R-MMU-9663248
Type
Complex
Species
Mus musculus
Compartment
Literature References
PubMed ID Title Journal Year
23658152 β-Actin and fascin-2 cooperate to maintain stereocilia length

Strandjord, DM, Ervasti, JM, Johnson, KR, Narayanan, P, Henderson, DM, Perrin, BJ

J. Neurosci. 2013
31001589 Critical role of spectrin in hearing development and deafness

Li, H, Zhang, Y, Liu, Y, Chu, C, Ni, G, Chen, X, Zhong, G, He, S, Yang, G, Chai, R, Zhong, C, Tian, C, Tang, M, Zhu, W, Qi, J

Sci Adv 2019
21526224 Eps8 regulates hair bundle length and functional maturation of mammalian auditory hair cells

Rüttiger, L, Knipper, M, Zampini, V, Furness, DN, Offenhauser, N, Johnson, SL, Di Fiore, PP, Hackney, CM, Franz, C, Marcotti, W, Xiong, H, Waldhaus, J, Masetto, S, Holley, MC

PLoS Biol. 2011
27811163 Plastin 1 widens stereocilia by transforming actin filament packing from hexagonal to liquid

Dumont, RA, Vijayakumar, S, Choi, D, Krey, JF, Kachar, B, Krystofiak, ES, Barr-Gillespie, PG, Rivero, F, Jones, SM

J. Cell Biol. 2016
7568224 Expression in cochlea and retina of myosin VIIa, the gene product defective in Usher syndrome type 1B

Corey, DP, Heintzelman, MB, Mooseker, MS, Santos-Sacchi, J, Hasson, T

Proc. Natl. Acad. Sci. U.S.A. 1995
28209736 Pejvakin, a Candidate Stereociliary Rootlet Protein, Regulates Hair Cell Function in a Cell-Autonomous Manner

Peng, AW, Kazmierczak, M, Shah, P, Puel, JL, Kazmierczak, P, Schwander, M, Lenoir, M, Franco, SJ, Harris, SL

J. Neurosci. 2017
19853587 Protein 4.1 expression in the developing hair cells of the mouse inner ear

Yokohama, M, Mochizuki, E, Kikkawa, Y, Yonekawa, H, Shitara, H, Brown, SD, Mburu, P, Yamakawa, H, Okumura, K

Brain Res. 2010
25683353 Noise-induced cochlear F-actin depolymerization is mediated via ROCK2/p-ERM signaling

Wang, X, Chen, J, Sha, SH, Han, Y

J. Neurochem. 2015
24285636 CLIC5 stabilizes membrane-actin filament linkages at the base of hair cell stereocilia in a molecular complex with radixin, taperin, and myosin VI

Gagnon, LH, Salles, FT, Andrade, LR, Johnson, KR, Tanda, S, Berryman, MA, Grati, M, Plona, KL, Kachar, B

Cytoskeleton (Hoboken) 2014
23918390 Progressive hearing loss and gradual deterioration of sensory hair bundles in the ears of mice lacking the actin-binding protein Eps8L2

Rüttiger, L, Goodyear, RJ, Knipper, M, Manor, U, Dai, Y, Furness, DN, Offenhauser, N, Tocchetti, A, Johnson, SL, Richardson, GP, Di Fiore, PP, Franz, C, Hackney, CM, Marcotti, W, Vijayakumar, S, Masetto, S, Olt, J, Kachar, B, Holley, MC, Jones, SM

Proc. Natl. Acad. Sci. U.S.A. 2013
20661277 Gelsolin plays a role in the actin polymerization complex of hair cell stereocilia

Parker, A, Kikkawa, Y, Brown, SD, Hilton, H, Mburu, P, Townsend, S, Romero, MR

PLoS ONE 2010
25772365 XIRP2, an actin-binding protein essential for inner ear hair-cell stereocilia

Wang, Q, Indzhykulian, A, Zhang, DS, Scheffer, DI, Chen, ZY, Xu, YJ, Shen, J, Karavitaki, KD, Corey, DP, Lin, JJ

Cell Rep 2015
30380417 GRXCR2 Regulates Taperin Localization Critical for Stereocilia Morphology and Hearing

Tung, CY, Luo, N, Perrin, BJ, Zhao, B, Liu, C

Cell Rep 2018
29874122 The stable actin core of mechanosensory stereocilia features continuous turnover of actin cross-linkers

Roy, P, Perrin, BJ

Mol. Biol. Cell 2018
24700109 Staurosporine-induced collapse of cochlear hair bundles

Richardson, GP, Goodyear, RJ, Warchol, ME, Ratnayaka, HS

J. Comp. Neurol. 2014
14983055 Radixin is a constituent of stereocilia in hair cells

Hudspeth, AJ, Pataky, F, Pironkova, R

Proc. Natl. Acad. Sci. U.S.A. 2004
30157177 Grxcr2 is required for stereocilia morphogenesis in the cochlea

Jung, JY, Schraders, M, Azaiez, H, Askew, C, Hunker, KL, Dolan, DF, Rehman, AU, Kohrman, DC, Smith, RJH, Raphael, Y, Kremer, H, Najmabadi, H, Avenarius, MR, Géléoc, GSG, Jones, SM

PLoS ONE 2018
20137774 Mutations in Grxcr1 are the basis for inner ear dysfunction in the pirouette mouse

Smith, RJ, Gagnon, LH, Hagiwara, N, Johnson, KR, Azaiez, H, Friedman, TB, Allen, ND, Hunker, KL, Belyantseva, IA, Zheng, L, Peters, LM, Kohrman, DC, Brilliant, MH, Raphael, Y, Najmabadi, H, Odeh, H, Avenarius, MR, Bartles, JR, Riazuddin, S, Skynner, MJ

Am. J. Hum. Genet. 2010
31217345 TRIOBP-5 sculpts stereocilia rootlets and stiffens supporting cells enabling hearing

Frolenkov, GI, Fenollar-Ferrer, C, Ikeya, M, Kiyonari, H, Friedman, TB, Kitajiri, SI, Wilson, EA, Wang, YX, Katsuno, T, Kaneko, M, Abe, T, Cartagena-Rivera, AX, Omori, K, Riordan, GP, Ohta, K, Tona, R, Rehman, A, Petralia, RS, Crump, SM, Ono, K, Belyantseva, IA, Ito, J, Imtiaz, A, Segawa, K, Fitzgerald, TS

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