Csf3 dimer:2xp-4Y-Csf3r:Lyn:p-Y-Jak1:p-Jak2:p-Syk:p-Hck:p-Tyk2:p-Y-Stat1,3,5 dissociates yielding Csf3 dimer:2xp-4Y-Csf3r:Lyn:p-Y-Jak1:p-Jak2:p-Syk:p-Hck:p-Tyk2 and p-Y-Stat1,3,5

Stable Identifier
R-MMU-9674931
Type
Reaction
Species
Mus musculus
Compartment
General
SVG |   | PPTX  | SBGN
Csf3 dimer:2xp-4Y-Csf3r:Lyn:p-Y-Jak1:p-Jak2:p-Syk:p-Hck:p-Tyk2:p-Y-Stat1,3,5 dissociates yielding Csf3 dimer:2xp-4Y-Csf3r:Lyn:p-Y-Jak1:p-Jak2:p-Syk:p-Hck:p-Tyk2 and p-Y-Stat1,3,5

After phosphorylation while bound to phospho-Csf3r at the plasma membrane, p-Stat1,3,5 dissociates from Csf3r prior to dimerizing and transiting to the nucleus (Nicholson et al. 1995, de Koning et al. 1996, Nicholson et al. 1996, Gits et al. 2006).

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