p-Y-Stat1,3,5 dimerize

Stable Identifier
R-MMU-9676912
Type
Reaction [transition]
Species
Mus musculus
Compartment
cytosol
ReviewStatus
5/5
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
p-Y-Stat1,3,5 dimerize
After being phosphorylated, Stat1, Stat3, and Stat5 (Stat5a and Stat5b) form homodimers (de Koning et al. 1996, Gits et al. 2006). Phospho-Stat1 and phospho-Stat3 can also form heterodimers (de Koning et al. 1996, Gits et al. 2006).
Literature References
PubMed ID Title Journal Year
8608222 The membrane-distal cytoplasmic region of human granulocyte colony-stimulating factor receptor is required for STAT3 but not STAT1 homodimer formation

van der Plas, DC, Schelen, AM, Barge, RM, Smith, L, Touw, IP, Löwenberg, B, Dong, F, de Koning, JP, Hoefsloot, LH

Blood 1996
17066093 Multiple pathways contribute to the hyperproliferative responses from truncated granulocyte colony-stimulating factor receptors

Ward, AC, Touw, IP, Carroll, HP, van Leeuwen, D, Gits, J

Leukemia 2006
Participants
Input
Output
Orthologous Events
p-Y-STAT1,3,5 dimerize (Homo sapiens)
Authored
May, B  (2020-02-23)
Reviewed
Touw, IP  (2020-12-12)
Created
May, B  (2020-02-23)
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