Kcnj2 transports K+ from the extracellular region to the cytosol

Stable Identifier
R-MMU-9729881
Type
Reaction [transition]
Species
Mus musculus
Compartment
General
SVG |   | PPTX  | SBGN
Kcnj2 transports K+ from the extracellular region to the cytosol

The Kcnj2 inward rectifying potassium channel preferentially transports K+ ions from the extracellular region to the cytosol (Ye et al. 2016). In type III taste cells, the increase in cytosolic H+ caused by acidic compounds inhibits the activity of KCNJ2 (Ye et al. 2016).

Literature References
PubMed ID Title Journal Year
26627720 The K+ channel KIR2.1 functions in tandem with proton influx to mediate sour taste transduction

Mulhall, EM, Liman, ER, Chick, WS, Hill-Eubanks, DC, Cooper, AJ, Nelson, MT, Ye, W, Kinnamon, SC, Chang, RB, Bushman, JD, Tu, YH, Wilson, CE

Proc Natl Acad Sci U S A 2016
Participants
Output
Catalyst Activity

inward rectifier potassium channel activity of Kcnj2 [plasma membrane]

This event is regulated
Negatively by
Regulator
Orthologous Events
Authored
Reviewed
Created
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