Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
phospho-p-S320-RIPK1 [cytosol]
Stable Identifier
R-MMU-9815498
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
cytosol
Synonyms
Q60855
Locations in the PathwayBrowser
Expand all
Signal Transduction (Mus musculus)
Death Receptor Signaling (Mus musculus)
TNF signaling (Mus musculus)
Regulation of TNFR1 signaling (Mus musculus)
MAPKAPK2 phosphorylates RIPK1 at S320 (Mus musculus)
TRAF2:TRADD:p-S320-RIPK1 [cytosol] (Mus musculus)
phospho-p-S320-RIPK1 [cytosol] (Mus musculus)
TNFR1-induced proapoptotic signaling (Mus musculus)
TRADD:TRAF2:RIP1 binds FADD (Mus musculus)
TRAF2:TRADD:p-S320-RIPK1 [cytosol] (Mus musculus)
phospho-p-S320-RIPK1 [cytosol] (Mus musculus)
External Reference Information
External Reference
UniProt:Q60855
Reference Genes
BioGPS Gene:19766
ENSEMBL:ENSMUSG00000021408
KEGG:mmu:19766
Monarch:19766
NCBI Gene:19766
UCSC:Q60855
Reference Transcript
RefSeq:NM_009068.3
RefSeq:XM_006516607.3
RefSeq:XM_006516609.3
Other Identifiers
10404506
130183_at
1419508_at
1439273_at
1449485_at
17286472
19766
4387682
4499854
4576677
4587400
4619144
4679401
4705696
4738836
4769386
4792006
4886540
4937728
4940735
4942812
4968495
4977703
4979747
5009799
5073064
5140039
5147951
5165706
5165855
5170973
5349756
5451391
5475993
5598996
5609742
97091_at
AA186144_at
A_51_P430952
A_52_P174775
A_52_P452740
A_55_P2506630
A_55_P2713935
GE33576
GO:0000165
GO:0001934
GO:0003824
GO:0004672
GO:0004674
GO:0004706
GO:0005123
GO:0005515
GO:0005524
GO:0005737
GO:0005739
GO:0005886
GO:0006355
GO:0006468
GO:0006915
GO:0006950
GO:0006954
GO:0006979
GO:0007165
GO:0007166
GO:0008625
GO:0010628
GO:0012501
GO:0016740
GO:0030163
GO:0031264
GO:0031349
GO:0031625
GO:0032757
GO:0032760
GO:0032991
GO:0033209
GO:0034612
GO:0035556
GO:0035591
GO:0036289
GO:0042327
GO:0042802
GO:0042803
GO:0043065
GO:0043066
GO:0043068
GO:0043123
GO:0043124
GO:0043226
GO:0043235
GO:0043410
GO:0043525
GO:0044877
GO:0045651
GO:0045944
GO:0046330
GO:0046777
GO:0050729
GO:0051092
GO:0060090
GO:0060545
GO:0060546
GO:0062100
GO:0065003
GO:0070105
GO:0070231
GO:0070266
GO:0070301
GO:0070513
GO:0071345
GO:0071356
GO:0071363
GO:0097191
GO:0097300
GO:0097342
GO:0097343
GO:0097527
GO:0106310
GO:0140096
GO:1900119
GO:1901026
GO:1901224
GO:1903265
GO:1903800
GO:1990000
GO:2000377
GO:2001237
GO:2001238
GO:2001240
ILMN_2753492
U25995_s_at
mMR026803
Participates
as a component of
TRAF2:TRADD:p-S320-RIPK1 [cytosol] (Mus musculus)
Other forms of this molecule
RIPK1 [cytosol]
K63polyUb-RIPK1 [cytosol]
phospho-p-S166-RIPK1 [cytosol]
phospho-p-S357-RIPK1 [cytosol]
phospho-K63,M1polyUb, p-T189-RIPK1 [cytosol]
polyUb-K377,K604,K634-RIPK1 [cytosol]
RIPK1(325-671) [cytosol]
RIPK1(1-324) [cytosol]
K63,M1polyUb-RIPK1 [cytosol]
phospho-K63,Met1polyUb-p-S25-RIPK1 [cytosol]
K48polyUb-K571,K604,K627-RIPK1 [cytosol]
PolyUb-RIPK1 [cytosol]
K48polyUb-RIPK1 [cytosol]
Inferred From
p-S320-RIPK1 [cytosol]
(Homo sapiens)
Modified Residues
Name
O-phospho-L-serine at 320 (in Homo sapiens)
Coordinate
320
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Cross References
RefSeq
XP_006516672.1
,
XP_006516670.1
,
NP_033094.3
ENSEMBL
ENSMUST00000021844
,
ENSMUSP00000129831
,
ENSMUSP00000021844
,
ENSMUST00000167374
PRO
Q60855
MGI
108212
GlyGen
Q60855
PDB
8IB0
Interactors (8)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q61160
1
Fadd [cytosol]
(R-MMU-54639)
0.886
9
UniProt:P25118
1
TNFRSF1A(30-45) [plasma membrane]
(R-MMU-5675738)
0.758
4
UniProt:P62991 UBIQ
0.609
2
UniProt:Q9QZL0
8
phospho-p-S199,227, K48pUb-363-RIPK3 [cytosol]
(R-MMU-9686933)
K33polyUb-K197,302,364-RIPK3 [cytosol]
(R-MMU-9794180)
OGlcNAc-T467-RIPK3 [cytosol]
(R-MMU-9687819)
RIPK3(329-518) [cytosol]
(R-MMU-9686937)
RIPK3(1-328) [cytosol]
(R-MMU-9686917)
Ub-K55,363-RIPK3 [cytosol]
(R-MMU-9688825)
phospho-p-S199,227-RIPK3 [cytosol]
(R-MMU-5218873)
RIPK3 [cytosol]
(R-MMU-450328)
0.589
4
UniProt:P01375 TNF
5
TNF(1-233) [plasma membrane]
(R-HSA-66220)
TNF(77-233) [extracellular region]
(R-HSA-976821)
TNF(1-76) [plasma membrane]
(R-HSA-8863120)
TNF(1-34) [plasma membrane]
(R-HSA-8863367)
TNF(52-76) [extracellular region]
(R-HSA-8863375)
0.576
4
UniProt:Q3U0V2
1
TRADD [cytosol]
(R-MMU-66376)
0.499
2
UniProt:P33896 Ifnar1
3
Ifnar1 [plasma membrane]
(R-MMU-912671)
Ifnar1 [plasma membrane]
(R-MMU-877334)
phospho-Ifnar1 [plasma membrane]
(R-MMU-909675)
0.463
2
UniProt:P47741
1
Tnfrsf4 [plasma membrane]
(R-MMU-5692210)
0.462
7
© 2025
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text