Pparg2 binds Rxra

Stable Identifier
R-MMU-9843278
Type
Reaction [binding]
Species
Mus musculus
Compartment
nucleoplasm
ReviewStatus
5/5
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Pparg2 binds Rxra
Mouse recombinant Phlda1 (Tdag51) inhibits formation of heterodimers of recombinant mouse Pparg2 and Rxra by competing with Rxra for binding to Pparg2 (Kim et al. 2021).
Literature References
PubMed ID Title Journal Year
33335079 T-Cell Death Associated Gene 51 Is a Novel Negative Regulator of PPARγ That Inhibits PPARγ-RXRα Heterodimer Formation in Adipogenesis

Kim, S, Lee, N, Park, ES, Yun, H, Ha, TU, Jeon, H, Yu, J, Choi, S, Shin, B, Yu, J, Rhee, SD, Choi, Y, Rho, J

Mol Cells 2021
Participants
Input
Output
This event is regulated
Negatively by
Regulator
Phlda1:Pparg2 [nucleoplasm] (Mus musculus)
Active Unit
Phlda1 [nucleoplasm]
Orthologous Events
PPARG binds RXRA (Homo sapiens)
Authored
Orlic-Milacic, M  (2023-09-06)
Reviewed
Khag, J  (2025-10-31)
Wang, SP  (2025-10-31)
Created
Orlic-Milacic, M  (2023-09-06)
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