PapA5 transforms mycocerosyl to PDIM

Stable Identifier
R-MTU-9635440
Type
Reaction [transition]
Species
Mycobacterium tuberculosis
Compartment
Synonyms
2 mycocerosyl + phthiocerol => dimycocerosyl phthiocerol + 2 Pks5
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Mtb PapA5 catalyzes the transesterification of mycocerosyl. This protein catalyzes the synthesis of dimycocerosyl phthiocerol from mycocerosyl and phthiocerol (Trivedi et al. 2005).

Literature References
PubMed ID Title Journal Year
15749014 Dissecting the mechanism and assembly of a complex virulence mycobacterial lipid

Trivedi, OA, Arora, P, Vats, A, Ansari, MZ, Tickoo, R, Sridharan, V, Mohanty, D, Gokhale, RS

Mol. Cell 2005
Participants
Participates
Catalyst Activity

transferase activity of PapA5 [cytosol]

Authored
Reviewed
Created
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