TGFBR2 is recruited to tight junctions-associated, Pard6a-bound, TGFBR1 after TGF-beta stimulation

Stable Identifier
R-NUL-2161160
Type
Reaction [binding]
Species
Homo sapiens
Compartment
cell junction, plasma membrane, extracellular region
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
TGFBR2 is recruited to tight junctions-associated, Pard6a-bound, TGFBR1 after TGF-beta stimulation

In human embryonic kidney cell line, HEK293, TGFBR2 binds TGFBR1 anchored to tight junctions through association with exogenously expressed FLAG-tagged mouse Pard6a (Ozdamar et al. 2005).

Literature References
PubMed ID Title Journal Year
15761148 Regulation of the polarity protein Par6 by TGFbeta receptors controls epithelial cell plasticity

Barrios-Rodiles, M, Zhang, Y, Wrana, JL, Wang, HR, Bose, R, Ozdamar, B

Science 2005
Participants
Input
Output
Orthologous Events
TGFBR2 is recruited to tight junctions after TGF-beta stimulation (Homo sapiens)
Authored
Orlic-Milacic, M  (2012-04-05)
Reviewed
Huang, T  (2012-05-14)
Created
Orlic-Milacic, M  (2012-03-09)
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