Activation of Fyn

Stable Identifier
R-NUL-421138
Type
Reaction [binding]
Species
Mus musculus
Compartment
extracellular region, plasma membrane
ReviewStatus
5/5
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Activation of Fyn
PlexinA1 and A2 are constitutively bound to the src family tyrosine kinase, Fyn. Stimulation with Sema3A causes Fyn activation and leads to the recruitment of Cdk5 into the complex.
Literature References
PubMed ID Title Journal Year
12372285 Fyn and Cdk5 mediate semaphorin-3A signaling, which is involved in regulation of dendrite orientation in cerebral cortex

Nakamura, F, Taniguchi, M, Ohno, S, Uchida, Y, Nakajima, O, Kudo, Y, Sasaki, Y, Kishida, R, Yagi, T, Nakayama, T, Goshima, Y, Ohshima, T, Cheng, C

Neuron 2002
17607942 The CRMP family of proteins and their role in Sema3A signaling

Strittmatter, SM, Schmidt, EF

Adv Exp Med Biol 2007
Participants
Input
Output
Orthologous Events
Activation of Fyn (Homo sapiens)
Authored
Garapati, P V  (2009-03-23)
Reviewed
Kikutani, H  (2009-09-02)
Kumanogoh, A  (2009-09-02)
Created
Garapati, P V  (2009-05-15)
Cite Us!