Doublecortin binds phosphorylated neurofascin

Stable Identifier
R-NUL-443772
Type
Reaction [binding]
Species
Homo sapiens
Compartment
cytosol, plasma membrane
ReviewStatus
5/5
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Doublecortin binds phosphorylated neurofascin
Doublecortin is a microtubule associated protein expressed in neurons. Mutated doublecortin has been linked to the neuronal migration disorder X linked subcortical laminar heterotopia (double cortex)/lissencephaly. It binds neurofascin when the FIGQY motif of the latter protein is phosphorylated.
Literature References
PubMed ID Title Journal Year
12223548 A new activity of doublecortin in recognition of the phospho-FIGQY tyrosine in the cytoplasmic domain of neurofascin

Bennett, V, Wu, YX, Kizhatil, K, Sen, A

J Neurosci 2002
Participants
Input
Output
Entity On Other Cell
Orthologous Events
Doublecortin binds phosphorylated neurofascin (Homo sapiens)
Authored
Garapati, P V  (2008-07-30)
Reviewed
Maness, PF  (2010-02-16)
Created
Garapati, P V  (2009-10-12)
Cite Us!