NAB2 binds Egr1 at the Cdk5r1 promoter

Stable Identifier
R-NUL-9616362
Type
Reaction [binding]
Species
Homo sapiens
Compartment
General
SVG |   | PPTX  | SBGN
NAB2 binds Egr1 at the Cdk5r1 promoter

Cotransfection of human NAB2 and constitutively active Xenopus MEK into PC12 cells inhibits the ERK-signaling dependent expression of Cdk5r1, without affecting the expression of Egr1 itself (Harada et al, 2001).

Literature References
PubMed ID Title Journal Year
11331872 ERK induces p35, a neuron-specific activator of Cdk5, through induction of Egr1

Harada, T, Morooka, T, Ogawa, S, Nishida, E

Nat. Cell Biol. 2001
Participants
Orthologous Events
Authored
Reviewed
Created
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