Active ALK binds Src

Stable Identifier
R-NUL-9700661
Type
Reaction [binding]
Species
Homo sapiens
Compartment
plasma membrane, cytosol
ReviewStatus
5/5
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Active ALK binds Src
The human NPM:ALK fusion interacts with SRC in a ALK-kinase dependent fashion when expressed in Ba/F3 cells (Cussac et al, 2004).
Literature References
PubMed ID Title Journal Year
14563642 Nucleophosmin-anaplastic lymphoma kinase of anaplastic large-cell lymphoma recruits, activates, and uses pp60c-src to mediate its mitogenicity

Roche, S, Duyster, J, Greenland, C, Morris, SW, Delsol, G, Bai, RY, Payrastre, B, Allouche, M, Cussac, D

Blood 2004
Participants
Input
Output
Orthologous Events
Active ALK binds SRC (Homo sapiens)
Authored
Rothfels, K  (2021-03-30)
Reviewed
Inghirami, G  (2021-05-04)
Created
Rothfels, K  (2020-09-16)
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