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POLE [nucleoplasm]
Stable Identifier
R-PFA-68473
Type
Protein [EntityWithAccessionedSequence]
Species
Plasmodium falciparum
Compartment
nucleoplasm
Synonyms
C6KTD8
Locations in the PathwayBrowser
Expand all
Cell Cycle (Plasmodium falciparum)
Cell Cycle, Mitotic (Plasmodium falciparum)
Mitotic G1 phase and G1/S transition (Plasmodium falciparum)
G1/S Transition (Plasmodium falciparum)
Activation of the pre-replicative complex (Plasmodium falciparum)
DNA polymerase alpha:primase binds at the origin (Plasmodium falciparum)
DNA polymerase alpha:primase:DNA polymerase alpha:origin complex [nucleoplasm] (Plasmodium falciparum)
DNA polymerase epsilon:origin complex [nucleoplasm] (Plasmodium falciparum)
DNA polymerase epsilon [nucleoplasm] (Plasmodium falciparum)
POLE [nucleoplasm] (Plasmodium falciparum)
DNA polymerase epsilon:origin complex [nucleoplasm] (Plasmodium falciparum)
DNA polymerase epsilon [nucleoplasm] (Plasmodium falciparum)
POLE [nucleoplasm] (Plasmodium falciparum)
DNA polymerase epsilon binds at the origin (Plasmodium falciparum)
DNA polymerase epsilon [nucleoplasm] (Plasmodium falciparum)
POLE [nucleoplasm] (Plasmodium falciparum)
DNA polymerase epsilon:origin complex [nucleoplasm] (Plasmodium falciparum)
DNA polymerase epsilon [nucleoplasm] (Plasmodium falciparum)
POLE [nucleoplasm] (Plasmodium falciparum)
S Phase (Plasmodium falciparum)
Synthesis of DNA (Plasmodium falciparum)
DNA replication initiation (Plasmodium falciparum)
The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer at the origin (Plasmodium falciparum)
DNA polymerase alpha:primase:DNA polymerase alpha:origin complex [nucleoplasm] (Plasmodium falciparum)
DNA polymerase epsilon:origin complex [nucleoplasm] (Plasmodium falciparum)
DNA polymerase epsilon [nucleoplasm] (Plasmodium falciparum)
POLE [nucleoplasm] (Plasmodium falciparum)
DNA polymerase epsilon [nucleoplasm] (Plasmodium falciparum)
POLE [nucleoplasm] (Plasmodium falciparum)
DNA Repair (Plasmodium falciparum)
Base Excision Repair (Plasmodium falciparum)
Resolution of Abasic Sites (AP sites) (Plasmodium falciparum)
Resolution of AP sites via the multiple-nucleotide patch replacement pathway (Plasmodium falciparum)
PCNA-Dependent Long Patch Base Excision Repair (Plasmodium falciparum)
LIG1 binds APEX1 and PCNA at SSB (Plasmodium falciparum)
APEX1:PCNA:POLD,POLE:RPA:RFC:SSB(3'poly-dNMP)-dsDNA [nucleoplasm] (Plasmodium falciparum)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Plasmodium falciparum)
POLD,POLE [nucleoplasm] (Plasmodium falciparum)
DNA polymerase epsilon [nucleoplasm] (Plasmodium falciparum)
POLE [nucleoplasm] (Plasmodium falciparum)
LIG1:APEX1:PCNA:POLD,POLE:RPA:RFC:SSB:(3'poly-dNMP)-dsDNA [nucleoplasm] (Plasmodium falciparum)
APEX1:PCNA:POLD,POLE:RPA:RFC:SSB(3'poly-dNMP)-dsDNA [nucleoplasm] (Plasmodium falciparum)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Plasmodium falciparum)
POLD,POLE [nucleoplasm] (Plasmodium falciparum)
DNA polymerase epsilon [nucleoplasm] (Plasmodium falciparum)
POLE [nucleoplasm] (Plasmodium falciparum)
LIG1 bound to APEX1 and PCNA ligates SSB (Plasmodium falciparum)
LIG1:APEX1:PCNA:POLD,POLE:RPA:RFC:SSB:(3'poly-dNMP)-dsDNA [nucleoplasm] (Plasmodium falciparum)
APEX1:PCNA:POLD,POLE:RPA:RFC:SSB(3'poly-dNMP)-dsDNA [nucleoplasm] (Plasmodium falciparum)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Plasmodium falciparum)
POLD,POLE [nucleoplasm] (Plasmodium falciparum)
DNA polymerase epsilon [nucleoplasm] (Plasmodium falciparum)
POLE [nucleoplasm] (Plasmodium falciparum)
LIG1:APEX1:PCNA:POLD,POLE:RPA:RFC:dsDNA [nucleoplasm] (Plasmodium falciparum)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Plasmodium falciparum)
POLD,POLE [nucleoplasm] (Plasmodium falciparum)
DNA polymerase epsilon [nucleoplasm] (Plasmodium falciparum)
POLE [nucleoplasm] (Plasmodium falciparum)
POLD,POLE-mediated DNA strand displacement synthesis (Plasmodium falciparum)
APEX1:FEN1:PCNA:POLD,POLE:RPA:RFC:SSB(3'dNMP-displaced 5'ddRP)-dsDNA [nucleoplasm] (Plasmodium falciparum)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Plasmodium falciparum)
POLD,POLE [nucleoplasm] (Plasmodium falciparum)
DNA polymerase epsilon [nucleoplasm] (Plasmodium falciparum)
POLE [nucleoplasm] (Plasmodium falciparum)
APEX1:FEN1:PCNA:POLD,POLE:RPA:RFC:SSB(3'poly-dNMP-displaced 5'ddRP flap)-dsDNA [nucleoplasm] (Plasmodium falciparum)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Plasmodium falciparum)
POLD,POLE [nucleoplasm] (Plasmodium falciparum)
DNA polymerase epsilon [nucleoplasm] (Plasmodium falciparum)
POLE [nucleoplasm] (Plasmodium falciparum)
POLD,POLE [nucleoplasm] (Plasmodium falciparum)
DNA polymerase epsilon [nucleoplasm] (Plasmodium falciparum)
POLE [nucleoplasm] (Plasmodium falciparum)
DNA Damage Bypass (Plasmodium falciparum)
Recognition of DNA damage by PCNA-containing replication complex (Plasmodium falciparum)
RAD18:UBE2B or RBX1:CUL4:DDB1:DTL monoubiquitinates PCNA (Plasmodium falciparum)
POLD,POLE [nucleoplasm] (Plasmodium falciparum)
DNA polymerase epsilon [nucleoplasm] (Plasmodium falciparum)
POLE [nucleoplasm] (Plasmodium falciparum)
RAD18:UBE2B,RBX1:CUL4:DDB1:DTL:PCNA:POLD,POLE:RPA:RFC:Damaged DNA Template [nucleoplasm] (Plasmodium falciparum)
PCNA:POLD,POLE:RPA:RFC:Damaged DNA Template [nucleoplasm] (Plasmodium falciparum)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Plasmodium falciparum)
POLD,POLE [nucleoplasm] (Plasmodium falciparum)
DNA polymerase epsilon [nucleoplasm] (Plasmodium falciparum)
POLE [nucleoplasm] (Plasmodium falciparum)
RAD18:UBE2B or RBX1:CUL4:DDB1:DTL ubiquitin ligase complex binds PCNA:POLD,POLE:RPA:RFC associated with damaged dsDNA (Plasmodium falciparum)
PCNA:POLD,POLE:RPA:RFC:Damaged DNA Template [nucleoplasm] (Plasmodium falciparum)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Plasmodium falciparum)
POLD,POLE [nucleoplasm] (Plasmodium falciparum)
DNA polymerase epsilon [nucleoplasm] (Plasmodium falciparum)
POLE [nucleoplasm] (Plasmodium falciparum)
RAD18:UBE2B,RBX1:CUL4:DDB1:DTL:PCNA:POLD,POLE:RPA:RFC:Damaged DNA Template [nucleoplasm] (Plasmodium falciparum)
PCNA:POLD,POLE:RPA:RFC:Damaged DNA Template [nucleoplasm] (Plasmodium falciparum)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Plasmodium falciparum)
POLD,POLE [nucleoplasm] (Plasmodium falciparum)
DNA polymerase epsilon [nucleoplasm] (Plasmodium falciparum)
POLE [nucleoplasm] (Plasmodium falciparum)
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template (Plasmodium falciparum)
Termination of translesion DNA synthesis (Plasmodium falciparum)
POLD,POLE binds deISGylated PCNA after TLS (Plasmodium falciparum)
PCNA:POLD,POLE:RPA:RFC:TLS-DNA Template [nucleoplasm] (Plasmodium falciparum)
POLD,POLE [nucleoplasm] (Plasmodium falciparum)
DNA polymerase epsilon [nucleoplasm] (Plasmodium falciparum)
POLE [nucleoplasm] (Plasmodium falciparum)
POLD,POLE [nucleoplasm] (Plasmodium falciparum)
DNA polymerase epsilon [nucleoplasm] (Plasmodium falciparum)
POLE [nucleoplasm] (Plasmodium falciparum)
Nucleotide Excision Repair (Plasmodium falciparum)
Global Genome Nucleotide Excision Repair (GG-NER) (Plasmodium falciparum)
Dual Incision in GG-NER (Plasmodium falciparum)
DNA polymerases delta, epsilon or kappa bind the GG-NER site (Plasmodium falciparum)
POLD,POLE [nucleoplasm] (Plasmodium falciparum)
DNA polymerase epsilon [nucleoplasm] (Plasmodium falciparum)
POLE [nucleoplasm] (Plasmodium falciparum)
Gap-filling DNA repair synthesis and ligation in GG-NER (Plasmodium falciparum)
Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in GG-NER (Plasmodium falciparum)
POLD,POLE [nucleoplasm] (Plasmodium falciparum)
DNA polymerase epsilon [nucleoplasm] (Plasmodium falciparum)
POLE [nucleoplasm] (Plasmodium falciparum)
Transcription-Coupled Nucleotide Excision Repair (TC-NER) (Plasmodium falciparum)
Dual incision in TC-NER (Plasmodium falciparum)
DNA polymerases delta, epsilon or kappa bind the TC-NER site (Plasmodium falciparum)
POLD,POLE [nucleoplasm] (Plasmodium falciparum)
DNA polymerase epsilon [nucleoplasm] (Plasmodium falciparum)
POLE [nucleoplasm] (Plasmodium falciparum)
Gap-filling DNA repair synthesis and ligation in TC-NER (Plasmodium falciparum)
Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER (Plasmodium falciparum)
POLD,POLE [nucleoplasm] (Plasmodium falciparum)
DNA polymerase epsilon [nucleoplasm] (Plasmodium falciparum)
POLE [nucleoplasm] (Plasmodium falciparum)
DNA Replication (Plasmodium falciparum)
DNA Replication Pre-Initiation (Plasmodium falciparum)
Activation of the pre-replicative complex (Plasmodium falciparum)
DNA polymerase alpha:primase binds at the origin (Plasmodium falciparum)
DNA polymerase alpha:primase:DNA polymerase alpha:origin complex [nucleoplasm] (Plasmodium falciparum)
DNA polymerase epsilon:origin complex [nucleoplasm] (Plasmodium falciparum)
DNA polymerase epsilon [nucleoplasm] (Plasmodium falciparum)
POLE [nucleoplasm] (Plasmodium falciparum)
DNA polymerase epsilon:origin complex [nucleoplasm] (Plasmodium falciparum)
DNA polymerase epsilon [nucleoplasm] (Plasmodium falciparum)
POLE [nucleoplasm] (Plasmodium falciparum)
DNA polymerase epsilon binds at the origin (Plasmodium falciparum)
DNA polymerase epsilon [nucleoplasm] (Plasmodium falciparum)
POLE [nucleoplasm] (Plasmodium falciparum)
DNA polymerase epsilon:origin complex [nucleoplasm] (Plasmodium falciparum)
DNA polymerase epsilon [nucleoplasm] (Plasmodium falciparum)
POLE [nucleoplasm] (Plasmodium falciparum)
Synthesis of DNA (Plasmodium falciparum)
DNA replication initiation (Plasmodium falciparum)
The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer at the origin (Plasmodium falciparum)
DNA polymerase alpha:primase:DNA polymerase alpha:origin complex [nucleoplasm] (Plasmodium falciparum)
DNA polymerase epsilon:origin complex [nucleoplasm] (Plasmodium falciparum)
DNA polymerase epsilon [nucleoplasm] (Plasmodium falciparum)
POLE [nucleoplasm] (Plasmodium falciparum)
DNA polymerase epsilon [nucleoplasm] (Plasmodium falciparum)
POLE [nucleoplasm] (Plasmodium falciparum)
External Reference Information
External Reference
UniProt:C6KTD8
Reference Genes
BioGPS Gene:3885768
ENSEMBL:PF3D7_0630300
KEGG Gene (Plasmodium falciparum):PF3D7_0630300
Monarch:3885768
NCBI Gene:3885768
PlasmoDB:PF3D7_0630300
Reference Transcript
RefSeq:XM_961192.1
Participates
as a component of
DNA polymerase epsilon [nucleoplasm] (Plasmodium falciparum)
Inferred From
POLE [nucleoplasm]
(Homo sapiens)
Cross References
RefSeq
XP_966285.1
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