Reactome | Homologues of RPS27A(77-156) [cytosol]

Homologues of RPS27A(77-156) [cytosol]

Stable Identifier

R-PFA-72363-3

Type

Set [DefinedSet]

Species

Plasmodium falciparum

Compartment

cytosol

Locations in the PathwayBrowser

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Metabolism of RNA (Plasmodium falciparum)

- Nonsense-Mediated Decay (NMD) (Plasmodium falciparum)
  - Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Plasmodium falciparum)
    - SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Plasmodium falciparum)
      - SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Plasmodium falciparum)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Plasmodium falciparum)
        
        80S ribosome [cytosol] (Plasmodium falciparum)
        
        40S ribosomal complex [cytosol] (Plasmodium falciparum)
        
        Homologues of RPS27A(77-156) [cytosol] (Plasmodium falciparum)
      - SMG1:UPF1:EJC:Translated mRNP [cytosol] (Plasmodium falciparum)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Plasmodium falciparum)
        
        80S ribosome [cytosol] (Plasmodium falciparum)
        
        40S ribosomal complex [cytosol] (Plasmodium falciparum)
        
        Homologues of RPS27A(77-156) [cytosol] (Plasmodium falciparum)
  - Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) (Plasmodium falciparum)
    - Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex (Plasmodium falciparum)
      - Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Plasmodium falciparum)
        
        80S ribosome [cytosol] (Plasmodium falciparum)
        
        40S ribosomal complex [cytosol] (Plasmodium falciparum)
        
        Homologues of RPS27A(77-156) [cytosol] (Plasmodium falciparum)
      - UPF1:eRF3 Complex on Translated mRNA [cytosol] (Plasmodium falciparum)
        
        Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Plasmodium falciparum)
        
        80S ribosome [cytosol] (Plasmodium falciparum)
        
        40S ribosomal complex [cytosol] (Plasmodium falciparum)
        
        Homologues of RPS27A(77-156) [cytosol] (Plasmodium falciparum)

Participants

members

Participates

as a component of

as an output of

UCHL3,USP7,USP9X cleaves RPS27A yielding ubiquitin (Plasmodium falciparum)

Inferred From

RPS27A(77-156) [cytosol] (Homo sapiens)

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