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RPL40 [cytosol]
Stable Identifier
R-PFA-72476
Type
Protein [EntityWithAccessionedSequence]
Species
Plasmodium falciparum
Compartment
cytosol
Synonyms
Q7KQK2
Locations in the PathwayBrowser
Expand all
Metabolism of RNA (Plasmodium falciparum)
Nonsense-Mediated Decay (NMD) (Plasmodium falciparum)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Plasmodium falciparum)
SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Plasmodium falciparum)
SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Plasmodium falciparum)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Plasmodium falciparum)
80S ribosome [cytosol] (Plasmodium falciparum)
60S ribosomal complex [cytosol] (Plasmodium falciparum)
Homologues of RPL40 [cytosol] (Plasmodium falciparum)
RPL40 [cytosol] (Plasmodium falciparum)
SMG1:UPF1:EJC:Translated mRNP [cytosol] (Plasmodium falciparum)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Plasmodium falciparum)
80S ribosome [cytosol] (Plasmodium falciparum)
60S ribosomal complex [cytosol] (Plasmodium falciparum)
Homologues of RPL40 [cytosol] (Plasmodium falciparum)
RPL40 [cytosol] (Plasmodium falciparum)
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) (Plasmodium falciparum)
Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex (Plasmodium falciparum)
Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Plasmodium falciparum)
80S ribosome [cytosol] (Plasmodium falciparum)
60S ribosomal complex [cytosol] (Plasmodium falciparum)
Homologues of RPL40 [cytosol] (Plasmodium falciparum)
RPL40 [cytosol] (Plasmodium falciparum)
UPF1:eRF3 Complex on Translated mRNA [cytosol] (Plasmodium falciparum)
Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Plasmodium falciparum)
80S ribosome [cytosol] (Plasmodium falciparum)
60S ribosomal complex [cytosol] (Plasmodium falciparum)
Homologues of RPL40 [cytosol] (Plasmodium falciparum)
RPL40 [cytosol] (Plasmodium falciparum)
Metabolism of proteins (Plasmodium falciparum)
Post-translational protein modification (Plasmodium falciparum)
Protein ubiquitination (Plasmodium falciparum)
Synthesis of active ubiquitin: roles of E1 and E2 enzymes (Plasmodium falciparum)
UCHL3,USP7,USP9X cleaves UBA52 yielding ubiquitin (Plasmodium falciparum)
Homologues of RPL40 [cytosol] (Plasmodium falciparum)
RPL40 [cytosol] (Plasmodium falciparum)
Translation (Plasmodium falciparum)
Eukaryotic Translation Initiation (Plasmodium falciparum)
Cap-dependent Translation Initiation (Plasmodium falciparum)
Formation of a pool of free 40S subunits (Plasmodium falciparum)
Release of 40S and 60S subunits from the 80S ribosome (Plasmodium falciparum)
60S ribosomal complex [cytosol] (Plasmodium falciparum)
Homologues of RPL40 [cytosol] (Plasmodium falciparum)
RPL40 [cytosol] (Plasmodium falciparum)
80S ribosome [cytosol] (Plasmodium falciparum)
60S ribosomal complex [cytosol] (Plasmodium falciparum)
Homologues of RPL40 [cytosol] (Plasmodium falciparum)
RPL40 [cytosol] (Plasmodium falciparum)
GTP hydrolysis and joining of the 60S ribosomal subunit (Plasmodium falciparum)
The 60S subunit joins the translation initiation complex (Plasmodium falciparum)
60S ribosomal complex [cytosol] (Plasmodium falciparum)
Homologues of RPL40 [cytosol] (Plasmodium falciparum)
RPL40 [cytosol] (Plasmodium falciparum)
80S:Met-tRNAi:mRNA:eIF5B:GTP [cytosol] (Plasmodium falciparum)
80S ribosome [cytosol] (Plasmodium falciparum)
60S ribosomal complex [cytosol] (Plasmodium falciparum)
Homologues of RPL40 [cytosol] (Plasmodium falciparum)
RPL40 [cytosol] (Plasmodium falciparum)
eIF5B:GTP is hydrolyzed and released (Plasmodium falciparum)
80S:Met-tRNAi:mRNA [cytosol] (Plasmodium falciparum)
80S ribosome [cytosol] (Plasmodium falciparum)
60S ribosomal complex [cytosol] (Plasmodium falciparum)
Homologues of RPL40 [cytosol] (Plasmodium falciparum)
RPL40 [cytosol] (Plasmodium falciparum)
80S:Met-tRNAi:mRNA:eIF5B:GTP [cytosol] (Plasmodium falciparum)
80S ribosome [cytosol] (Plasmodium falciparum)
60S ribosomal complex [cytosol] (Plasmodium falciparum)
Homologues of RPL40 [cytosol] (Plasmodium falciparum)
RPL40 [cytosol] (Plasmodium falciparum)
L13a-mediated translational silencing of Ceruloplasmin expression (Plasmodium falciparum)
Dissociation of L13a from the 60s ribosomal subunit (Plasmodium falciparum)
60S ribosomal complex [cytosol] (Plasmodium falciparum)
Homologues of RPL40 [cytosol] (Plasmodium falciparum)
RPL40 [cytosol] (Plasmodium falciparum)
60s ribosomal complex lacking L13a subunit [cytosol] (Plasmodium falciparum)
Homologues of RPL40 [cytosol] (Plasmodium falciparum)
RPL40 [cytosol] (Plasmodium falciparum)
Ribosome-associated quality control (Plasmodium falciparum)
PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA (Plasmodium falciparum)
ABCE1:ATP binds PELO:HBS1L-1:GTP:80S ribosome:non-stop mRNA:peptidyl-tRNA with nascent peptide and HBS1L-1:GDP is released (Plasmodium falciparum)
ABCE1:ATP:PELO:80S Ribosome:non-stop mRNA:peptidyl-tRNA with elongating peptide [cytosol] (Plasmodium falciparum)
80S Ribosome:non-stop mRNA:peptidyl-tRNA with elongating peptide [cytosol] (Plasmodium falciparum)
80S ribosome [cytosol] (Plasmodium falciparum)
60S ribosomal complex [cytosol] (Plasmodium falciparum)
Homologues of RPL40 [cytosol] (Plasmodium falciparum)
RPL40 [cytosol] (Plasmodium falciparum)
PELO:HBS1L-1:GTP:80S ribosome:non-stop mRNA:peptidyl-tRNA with nascent peptide [cytosol] (Plasmodium falciparum)
80S Ribosome:non-stop mRNA:peptidyl-tRNA with elongating peptide [cytosol] (Plasmodium falciparum)
80S ribosome [cytosol] (Plasmodium falciparum)
60S ribosomal complex [cytosol] (Plasmodium falciparum)
Homologues of RPL40 [cytosol] (Plasmodium falciparum)
RPL40 [cytosol] (Plasmodium falciparum)
ABCE1:PELO:80S Ribosome:non-stop mRNA:peptidyl-tRNA with elongating peptide dissociates yielding ABCE1:40S ribosomal subunit, PELO, and 60S ribosomal subunit:peptidyl-tRNA with nascent peptide (Plasmodium falciparum)
60S ribosomal subunit:peptidyl-tRNA with nascent peptide [cytosol] (Plasmodium falciparum)
60S ribosomal complex [cytosol] (Plasmodium falciparum)
Homologues of RPL40 [cytosol] (Plasmodium falciparum)
RPL40 [cytosol] (Plasmodium falciparum)
ABCE1:ATP:PELO:80S Ribosome:non-stop mRNA:peptidyl-tRNA with elongating peptide [cytosol] (Plasmodium falciparum)
80S Ribosome:non-stop mRNA:peptidyl-tRNA with elongating peptide [cytosol] (Plasmodium falciparum)
80S ribosome [cytosol] (Plasmodium falciparum)
60S ribosomal complex [cytosol] (Plasmodium falciparum)
Homologues of RPL40 [cytosol] (Plasmodium falciparum)
RPL40 [cytosol] (Plasmodium falciparum)
PELO:HBS1L-1:GTP binds 80S ribosome:non-stop mRNA:peptidyl-tRNA with nascent peptide (Plasmodium falciparum)
80S Ribosome:non-stop mRNA:peptidyl-tRNA with elongating peptide [cytosol] (Plasmodium falciparum)
80S ribosome [cytosol] (Plasmodium falciparum)
60S ribosomal complex [cytosol] (Plasmodium falciparum)
Homologues of RPL40 [cytosol] (Plasmodium falciparum)
RPL40 [cytosol] (Plasmodium falciparum)
PELO:HBS1L-1:GTP:80S ribosome:non-stop mRNA:peptidyl-tRNA with nascent peptide [cytosol] (Plasmodium falciparum)
80S Ribosome:non-stop mRNA:peptidyl-tRNA with elongating peptide [cytosol] (Plasmodium falciparum)
80S ribosome [cytosol] (Plasmodium falciparum)
60S ribosomal complex [cytosol] (Plasmodium falciparum)
Homologues of RPL40 [cytosol] (Plasmodium falciparum)
RPL40 [cytosol] (Plasmodium falciparum)
Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide (Plasmodium falciparum)
LTN1 K48 polyubiquitinates the nascent peptide in NEMF:60S ribosomal subunit:peptidyl-tRNA with nascent peptide (Plasmodium falciparum)
LTN1:TCF25:NEMF:60S ribosomal subunit:peptidyl-tRNA with K48polyUb-nascent peptide-Ala [cytosol] (Plasmodium falciparum)
60S ribosomal complex [cytosol] (Plasmodium falciparum)
Homologues of RPL40 [cytosol] (Plasmodium falciparum)
RPL40 [cytosol] (Plasmodium falciparum)
LTN1:TCF25:NEMF:60S ribosomal subunit:peptidyl-tRNA with nascent peptide-Ala [cytosol] (Plasmodium falciparum)
60S ribosomal complex [cytosol] (Plasmodium falciparum)
Homologues of RPL40 [cytosol] (Plasmodium falciparum)
RPL40 [cytosol] (Plasmodium falciparum)
NEMF binds 60S ribosomal subunit:peptidyl-tRNA with nascent peptide (Plasmodium falciparum)
60S ribosomal subunit:peptidyl-tRNA with nascent peptide [cytosol] (Plasmodium falciparum)
60S ribosomal complex [cytosol] (Plasmodium falciparum)
Homologues of RPL40 [cytosol] (Plasmodium falciparum)
RPL40 [cytosol] (Plasmodium falciparum)
NEMF:60S ribosomal subunit:peptidyl-tRNA with nascent peptide [cytosol] (Plasmodium falciparum)
60S ribosomal complex [cytosol] (Plasmodium falciparum)
Homologues of RPL40 [cytosol] (Plasmodium falciparum)
RPL40 [cytosol] (Plasmodium falciparum)
RCHY1 binds alanine-tailed nascent peptide and Ub:UBE2D2 (Plasmodium falciparum)
NEMF:60S ribosomal subunit:peptidyl-tRNA with nascent peptide-Ala [cytosol] (Plasmodium falciparum)
60S ribosomal complex [cytosol] (Plasmodium falciparum)
Homologues of RPL40 [cytosol] (Plasmodium falciparum)
RPL40 [cytosol] (Plasmodium falciparum)
ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA (Plasmodium falciparum)
ZNF598 K63 polyubiquitinates RPS10 (eS10) and RPS20 (uS10) of the 40S ribosomal subunit (Plasmodium falciparum)
K63polyUb-80S Ribosome:no-go mRNA:peptidyl-tRNA with elongating peptide [cytosol] (Plasmodium falciparum)
K63polyUb-80S ribosome [cytosol] (Plasmodium falciparum)
60S ribosomal complex [cytosol] (Plasmodium falciparum)
Homologues of RPL40 [cytosol] (Plasmodium falciparum)
RPL40 [cytosol] (Plasmodium falciparum)
ZNF598:Ub:UBE2D1,2,3:80S Ribosome:mRNA:peptidyl-tRNA with nascent peptide [cytosol] (Plasmodium falciparum)
80S Ribosome:no-go mRNA:peptidyl-tRNA with elongating peptide [cytosol] (Plasmodium falciparum)
80S ribosome [cytosol] (Plasmodium falciparum)
60S ribosomal complex [cytosol] (Plasmodium falciparum)
Homologues of RPL40 [cytosol] (Plasmodium falciparum)
RPL40 [cytosol] (Plasmodium falciparum)
ZNF598 and Ub:UBE2D1,2,3 bind stalled 80S ribosome (Plasmodium falciparum)
80S Ribosome:no-go mRNA:peptidyl-tRNA with elongating peptide [cytosol] (Plasmodium falciparum)
80S ribosome [cytosol] (Plasmodium falciparum)
60S ribosomal complex [cytosol] (Plasmodium falciparum)
Homologues of RPL40 [cytosol] (Plasmodium falciparum)
RPL40 [cytosol] (Plasmodium falciparum)
ZNF598:Ub:UBE2D1,2,3:80S Ribosome:mRNA:peptidyl-tRNA with nascent peptide [cytosol] (Plasmodium falciparum)
80S Ribosome:no-go mRNA:peptidyl-tRNA with elongating peptide [cytosol] (Plasmodium falciparum)
80S ribosome [cytosol] (Plasmodium falciparum)
60S ribosomal complex [cytosol] (Plasmodium falciparum)
Homologues of RPL40 [cytosol] (Plasmodium falciparum)
RPL40 [cytosol] (Plasmodium falciparum)
SRP-dependent cotranslational protein targeting to membrane (Plasmodium falciparum)
Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP) (Plasmodium falciparum)
SRP:polypeptide+signal:ribosome [cytosol] (Plasmodium falciparum)
ribosome:mRNA:polypeptide+signal [cytosol] (Plasmodium falciparum)
80S ribosome [cytosol] (Plasmodium falciparum)
60S ribosomal complex [cytosol] (Plasmodium falciparum)
Homologues of RPL40 [cytosol] (Plasmodium falciparum)
RPL40 [cytosol] (Plasmodium falciparum)
ribosome:mRNA:polypeptide+signal [cytosol] (Plasmodium falciparum)
80S ribosome [cytosol] (Plasmodium falciparum)
60S ribosomal complex [cytosol] (Plasmodium falciparum)
Homologues of RPL40 [cytosol] (Plasmodium falciparum)
RPL40 [cytosol] (Plasmodium falciparum)
External Reference Information
External Reference
UniProt:Q7KQK2
Reference Genes
BioGPS Gene:811170
ENSEMBL:PF3D7_1211800
KEGG:pfa:PF3D7_1211800
Monarch:811170
NCBI Gene:811170
PlasmoDB:PF3D7_1211800
UCSC:Q7KQK2
Reference Transcript
RefSeq:XM_001350490.1
Participates
as a member of
Homologues of RPL40 [cytosol] (Plasmodium falciparum)
Other forms of this molecule
RPS27A(77-156) [nucleoplasm]
N6-glycyl-L-lysine-UBC(457-532) [cytosol]
N6-glycyl-L-lysine-UBC(609-684) [cytosol]
N6-glycyl-L-lysine-UBC(229-304) [cytosol]
N6-glycyl-L-lysine-UBC(533-608) [cytosol]
N6-glycyl-L-lysine-UBB(153-228) [cytosol]
N6-glycyl-L-lysine-UBC(305-380) [cytosol]
N6-glycyl-L-lysine-UBB(77-152) [cytosol]
N6-glycyl-L-lysine-RPS27A(1-76) [cytosol]
N6-glycyl-L-lysine-UBC(381-456) [cytosol]
phospho-adenylatedG608-UBC(533-608) [nucleoplasm]
phospho-adenylatedG380-UBC(305-380) [nucleoplasm]
phospho-adenylatedG532-UBC(457-532) [nucleoplasm]
phospho-adenylatedG304-UBC(229-304) [nucleoplasm]
phospho-adenylatedG152-UBB(77-152) [nucleoplasm]
phospho-adenylatedG684-UBC(609-684) [nucleoplasm]
phospho-adenylatedG228-UBB(153-228) [nucleoplasm]
phospho-adenylatedG456-UBC(381-456) [nucleoplasm]
phospho-adenylatedG76-UBA52(1-76) [nucleoplasm]
UBB [cytosol]
UBA52(1-128) [cytosol]
UBC [cytosol]
RPS27A [cytosol]
phospho-adenylatedG380-UBC(305-380) [cytosol]
phospho-adenylatedG608-UBC(533-608) [cytosol]
phospho-adenylatedG304-UBC(229-304) [cytosol]
phospho-adenylatedG684-UBC(609-684) [cytosol]
phospho-adenylatedG152-UBB(77-152) [cytosol]
phospho-adenylatedG532-UBC(457-532) [cytosol]
phospho-adenylatedG228-UBB(153-228) [cytosol]
phospho-adenylatedG76-UBA52(1-76) [cytosol]
phospho-adenylatedG456-UBC(381-456) [cytosol]
Ub-257-UBC(229-304) [cytosol]
Ub-333-UBC(305-380) [cytosol]
Ub-409-UBC(381-456) [cytosol]
Ub-485-UBC(457-532) [cytosol]
Ub-561-UBC(533-608) [cytosol]
Ub-105-UBB(77-152) [cytosol]
Ub-181-UBB(153-228) [cytosol]
Ub-637-UBC(609-684) [cytosol]
Ub-29-RPS27A(1-76) [cytosol]
Ub-310-UBC(305-380) [cytosol]
Ub-462-UBC(457-532) [cytosol]
Ub-386-UBC(381-456) [cytosol]
Ub-538-UBC(533-608) [cytosol]
Ub-158-UBB(153-228) [cytosol]
Ub-6-RPS27A(1-76) [cytosol]
Ub-614-UBC(609-684) [cytosol]
Ub-234-UBC(229-304) [cytosol]
Ub-82-UBB(77-152) [cytosol]
Ub-255-UBC(229-304) [cytosol]
Ub-483-UBC(457-532) [cytosol]
Ub-559-UBC(533-608) [cytosol]
Ub-635-UBC(609-684) [cytosol]
Ub-331-UBC(305-380) [cytosol]
Ub-407-UBC(381-456) [cytosol]
Ub-103-UBB(77-152) [cytosol]
Ub-179-UBB(153-228) [cytosol]
Ub-27-RPS27A(1-76) [cytosol]
Ub-489-UBC(457-532) [cytosol]
Ub-337-UBC(305-380) [cytosol]
Ub-641-UBC(609-684) [cytosol]
Ub-413-UBC(381-456) [cytosol]
Ub-261-UBC(229-304) [cytosol]
Ub-109-UBB(77-152) [cytosol]
Ub-565-UBC(533-608) [cytosol]
Ub-33-RPS27A(1-76) [cytosol]
Ub-185-UBB(153-228) [cytosol]
RPS27A(77-156) [cytosol]
Ub-619-UBC(609-684) [cytosol]
Ub-163-UBB(153-228) [cytosol]
Ub-467-UBC(457-532) [cytosol]
Ub-11-RPS27A(1-76) [cytosol]
Ub-543-UBC(533-608) [cytosol]
Ub-391-UBC(381-456) [cytosol]
Ub-315-UBC(305-380) [cytosol]
Ub-87-UBB(77-152) [cytosol]
Ub-239-UBC(229-304) [cytosol]
UBC(229-304) [nucleoplasm]
UBC(381-456) [nucleoplasm]
UBC(305-380) [nucleoplasm]
UBC(457-532) [nucleoplasm]
UBC(533-608) [nucleoplasm]
UBC(609-684) [nucleoplasm]
UBB(77-152) [nucleoplasm]
RPS27A(1-76) [nucleoplasm]
UBB(153-228) [nucleoplasm]
Ub-671-UBC(609-684) [nucleoplasm]
Ub-443-UBC(381-456) [nucleoplasm]
Ub-215-UBB(153-228) [nucleoplasm]
Ub-367-UBC(305-380) [nucleoplasm]
Ub-139-UBB(77-152) [nucleoplasm]
Ub-519-UBC(457-532) [nucleoplasm]
Ub-595-UBC(533-608) [nucleoplasm]
Ub-291-UBC(229-304) [nucleoplasm]
Ub-63-RPS27A(1-76) [nucleoplasm]
Ub-443-UBC(381-456) [cytosol]
Ub-519-UBC(457-532) [cytosol]
Ub-63-RPS27A(1-76) [cytosol]
Ub-671-UBC(609-684) [cytosol]
Ub-367-UBC(305-380) [cytosol]
Ub-291-UBC(229-304) [cytosol]
Ub-139-UBB(77-152) [cytosol]
Ub-215-UBB(153-228) [cytosol]
Ub-595-UBC(533-608) [cytosol]
RPS27A(1-76) [cytosol]
UBB(77-152) [cytosol]
UBC(533-608) [cytosol]
UBC(305-380) [cytosol]
UBB(153-228) [cytosol]
UBC(609-684) [cytosol]
UBC(229-304) [cytosol]
UBC(381-456) [cytosol]
UBC(457-532) [cytosol]
Ub-352-UBC(305-380) [cytosol]
Ub-200-UBB(153-228) [cytosol]
Ub-124-UBB(77-152) [cytosol]
Ub-276-UBC(229-304) [cytosol]
Ub-48-RPS27A(1-76) [cytosol]
Ub-580-UBC(533-608) [cytosol]
Ub-504-UBC(457-532) [cytosol]
Ub-428-UBC(381-456) [cytosol]
Ub-656-UBC(609-684) [cytosol]
Inferred From
RPL40 [cytosol]
(Homo sapiens)
Cross References
RefSeq
XP_001350526.1
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