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About
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NRGs/EGFLs:p-ERBB4cyt1:p-6Y-ERBB2 [plasma membrane]
Stable Identifier
R-RNO-1250316
Type
Complex
Species
Rattus norvegicus
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Signal Transduction (Rattus norvegicus)
Intracellular signaling by second messengers (Rattus norvegicus)
PIP3 activates AKT signaling (Rattus norvegicus)
Negative regulation of the PI3K/AKT network (Rattus norvegicus)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Rattus norvegicus)
PI3K phosphorylates PIP2 to PIP3 (Rattus norvegicus)
Activator:PI3K [plasma membrane] (Rattus norvegicus)
NRGs/EGFLs:p-ERBB4cyt1:p-ERBB2:PI3K [plasma membrane] (Rattus norvegicus)
Phosphorylated ERBB2:ERBB4cyt1 heterodimers [plasma membrane] (Rattus norvegicus)
NRGs/EGFLs:p-ERBB4cyt1:p-6Y-ERBB2 [plasma membrane] (Rattus norvegicus)
PI3K phosphorylates PIP2 to PIP3 (Rattus norvegicus)
Activator:PI3K [plasma membrane] (Rattus norvegicus)
NRGs/EGFLs:p-ERBB4cyt1:p-ERBB2:PI3K [plasma membrane] (Rattus norvegicus)
Phosphorylated ERBB2:ERBB4cyt1 heterodimers [plasma membrane] (Rattus norvegicus)
NRGs/EGFLs:p-ERBB4cyt1:p-6Y-ERBB2 [plasma membrane] (Rattus norvegicus)
MAPK family signaling cascades (Rattus norvegicus)
MAPK1/MAPK3 signaling (Rattus norvegicus)
RAF/MAP kinase cascade (Rattus norvegicus)
RAS GEFs promote RAS nucleotide exchange (Rattus norvegicus)
RAS GEFs [plasma membrane] (Rattus norvegicus)
GRB2:SOS1:p-Y349,350-SHC1:Phosphorylated ERBB2 heterodimers [plasma membrane] (Rattus norvegicus)
p-Y349,350-SHC1:Phosphorylated ERBB2 heterodimers [plasma membrane] (Rattus norvegicus)
p-ERBB2 heterodimers [plasma membrane] (Rattus norvegicus)
p-6Y-ERBB2 heterodimers [plasma membrane] (Rattus norvegicus)
NRGs/EGFLs:p-ERBB4:p-6Y-ERBB2 [plasma membrane] (Rattus norvegicus)
NRGs/EGFLs:p-ERBB4cyt1:p-6Y-ERBB2 [plasma membrane] (Rattus norvegicus)
NRGs/EGFLs:p-ERBB4:p-ERBB2:GRB2:SOS1 [plasma membrane] (Rattus norvegicus)
Phosphorylated ERBB2:ERBB4 heterodimers [plasma membrane] (Rattus norvegicus)
Phosphorylated ERBB2:ERBB4cyt1 heterodimers [plasma membrane] (Rattus norvegicus)
NRGs/EGFLs:p-ERBB4cyt1:p-6Y-ERBB2 [plasma membrane] (Rattus norvegicus)
Signaling by Non-Receptor Tyrosine Kinases (Rattus norvegicus)
Signaling by PTK6 (Rattus norvegicus)
ERBB2 Activates PTK6 Signaling (Rattus norvegicus)
Activated ERBB2 binds PTK6 (BRK) (Rattus norvegicus)
p-ERBB2 heterodimers [plasma membrane] (Rattus norvegicus)
p-6Y-ERBB2 heterodimers [plasma membrane] (Rattus norvegicus)
NRGs/EGFLs:p-ERBB4:p-6Y-ERBB2 [plasma membrane] (Rattus norvegicus)
NRGs/EGFLs:p-ERBB4cyt1:p-6Y-ERBB2 [plasma membrane] (Rattus norvegicus)
p-ERBB2 heterodimers:PTK6 [plasma membrane] (Rattus norvegicus)
p-ERBB2 heterodimers [plasma membrane] (Rattus norvegicus)
p-6Y-ERBB2 heterodimers [plasma membrane] (Rattus norvegicus)
NRGs/EGFLs:p-ERBB4:p-6Y-ERBB2 [plasma membrane] (Rattus norvegicus)
NRGs/EGFLs:p-ERBB4cyt1:p-6Y-ERBB2 [plasma membrane] (Rattus norvegicus)
ERBB2 promotes PTK6 autophosphorylation (Rattus norvegicus)
p-ERBB2 heterodimers [plasma membrane] (Rattus norvegicus)
p-6Y-ERBB2 heterodimers [plasma membrane] (Rattus norvegicus)
NRGs/EGFLs:p-ERBB4:p-6Y-ERBB2 [plasma membrane] (Rattus norvegicus)
NRGs/EGFLs:p-ERBB4cyt1:p-6Y-ERBB2 [plasma membrane] (Rattus norvegicus)
p-ERBB2 heterodimers:PTK6 [plasma membrane] (Rattus norvegicus)
p-ERBB2 heterodimers [plasma membrane] (Rattus norvegicus)
p-6Y-ERBB2 heterodimers [plasma membrane] (Rattus norvegicus)
NRGs/EGFLs:p-ERBB4:p-6Y-ERBB2 [plasma membrane] (Rattus norvegicus)
NRGs/EGFLs:p-ERBB4cyt1:p-6Y-ERBB2 [plasma membrane] (Rattus norvegicus)
Signaling by Receptor Tyrosine Kinases (Rattus norvegicus)
Signaling by ERBB2 (Rattus norvegicus)
Downregulation of ERBB2 signaling (Rattus norvegicus)
MATK (CSK homologous kinase) binds phosphorylated ERBB2 (Rattus norvegicus)
p-ERBB2 heterodimers [plasma membrane] (Rattus norvegicus)
p-6Y-ERBB2 heterodimers [plasma membrane] (Rattus norvegicus)
NRGs/EGFLs:p-ERBB4:p-6Y-ERBB2 [plasma membrane] (Rattus norvegicus)
NRGs/EGFLs:p-ERBB4cyt1:p-6Y-ERBB2 [plasma membrane] (Rattus norvegicus)
p-ERBB2 heterodimers:MATK [plasma membrane] (Rattus norvegicus)
p-ERBB2 heterodimers [plasma membrane] (Rattus norvegicus)
p-6Y-ERBB2 heterodimers [plasma membrane] (Rattus norvegicus)
NRGs/EGFLs:p-ERBB4:p-6Y-ERBB2 [plasma membrane] (Rattus norvegicus)
NRGs/EGFLs:p-ERBB4cyt1:p-6Y-ERBB2 [plasma membrane] (Rattus norvegicus)
PTPN12 dephosphorylates ERBB2 on tyrosine Y1248 (Rattus norvegicus)
p-ERBB2 heterodimers [plasma membrane] (Rattus norvegicus)
p-6Y-ERBB2 heterodimers [plasma membrane] (Rattus norvegicus)
NRGs/EGFLs:p-ERBB4:p-6Y-ERBB2 [plasma membrane] (Rattus norvegicus)
NRGs/EGFLs:p-ERBB4cyt1:p-6Y-ERBB2 [plasma membrane] (Rattus norvegicus)
ERBB2 Activates PTK6 Signaling (Rattus norvegicus)
Activated ERBB2 binds PTK6 (BRK) (Rattus norvegicus)
p-ERBB2 heterodimers [plasma membrane] (Rattus norvegicus)
p-6Y-ERBB2 heterodimers [plasma membrane] (Rattus norvegicus)
NRGs/EGFLs:p-ERBB4:p-6Y-ERBB2 [plasma membrane] (Rattus norvegicus)
NRGs/EGFLs:p-ERBB4cyt1:p-6Y-ERBB2 [plasma membrane] (Rattus norvegicus)
p-ERBB2 heterodimers:PTK6 [plasma membrane] (Rattus norvegicus)
p-ERBB2 heterodimers [plasma membrane] (Rattus norvegicus)
p-6Y-ERBB2 heterodimers [plasma membrane] (Rattus norvegicus)
NRGs/EGFLs:p-ERBB4:p-6Y-ERBB2 [plasma membrane] (Rattus norvegicus)
NRGs/EGFLs:p-ERBB4cyt1:p-6Y-ERBB2 [plasma membrane] (Rattus norvegicus)
ERBB2 promotes PTK6 autophosphorylation (Rattus norvegicus)
p-ERBB2 heterodimers [plasma membrane] (Rattus norvegicus)
p-6Y-ERBB2 heterodimers [plasma membrane] (Rattus norvegicus)
NRGs/EGFLs:p-ERBB4:p-6Y-ERBB2 [plasma membrane] (Rattus norvegicus)
NRGs/EGFLs:p-ERBB4cyt1:p-6Y-ERBB2 [plasma membrane] (Rattus norvegicus)
p-ERBB2 heterodimers:PTK6 [plasma membrane] (Rattus norvegicus)
p-ERBB2 heterodimers [plasma membrane] (Rattus norvegicus)
p-6Y-ERBB2 heterodimers [plasma membrane] (Rattus norvegicus)
NRGs/EGFLs:p-ERBB4:p-6Y-ERBB2 [plasma membrane] (Rattus norvegicus)
NRGs/EGFLs:p-ERBB4cyt1:p-6Y-ERBB2 [plasma membrane] (Rattus norvegicus)
ERBB2 Regulates Cell Motility (Rattus norvegicus)
MEMO1 binds RHOA:GTP:DIAPH1 (Rattus norvegicus)
p-ERBB2 heterodimers:MEMO1 [plasma membrane] (Rattus norvegicus)
p-ERBB2 heterodimers [plasma membrane] (Rattus norvegicus)
p-6Y-ERBB2 heterodimers [plasma membrane] (Rattus norvegicus)
NRGs/EGFLs:p-ERBB4:p-6Y-ERBB2 [plasma membrane] (Rattus norvegicus)
NRGs/EGFLs:p-ERBB4cyt1:p-6Y-ERBB2 [plasma membrane] (Rattus norvegicus)
p-ERBB2 heterodimers:MEMO1:RHOA:GTP:DIAPH1 [plasma membrane] (Rattus norvegicus)
p-ERBB2 heterodimers:MEMO1 [plasma membrane] (Rattus norvegicus)
p-ERBB2 heterodimers [plasma membrane] (Rattus norvegicus)
p-6Y-ERBB2 heterodimers [plasma membrane] (Rattus norvegicus)
NRGs/EGFLs:p-ERBB4:p-6Y-ERBB2 [plasma membrane] (Rattus norvegicus)
NRGs/EGFLs:p-ERBB4cyt1:p-6Y-ERBB2 [plasma membrane] (Rattus norvegicus)
Phosphorylated ERBB2 heterodimers bind MEMO1 (Rattus norvegicus)
p-ERBB2 heterodimers [plasma membrane] (Rattus norvegicus)
p-6Y-ERBB2 heterodimers [plasma membrane] (Rattus norvegicus)
NRGs/EGFLs:p-ERBB4:p-6Y-ERBB2 [plasma membrane] (Rattus norvegicus)
NRGs/EGFLs:p-ERBB4cyt1:p-6Y-ERBB2 [plasma membrane] (Rattus norvegicus)
p-ERBB2 heterodimers:MEMO1 [plasma membrane] (Rattus norvegicus)
p-ERBB2 heterodimers [plasma membrane] (Rattus norvegicus)
p-6Y-ERBB2 heterodimers [plasma membrane] (Rattus norvegicus)
NRGs/EGFLs:p-ERBB4:p-6Y-ERBB2 [plasma membrane] (Rattus norvegicus)
NRGs/EGFLs:p-ERBB4cyt1:p-6Y-ERBB2 [plasma membrane] (Rattus norvegicus)
GRB2 events in ERBB2 signaling (Rattus norvegicus)
GRB2:SOS1 complex binds phosphorylated ERBB4:ERBB2 heterodimers (Rattus norvegicus)
NRGs/EGFLs:p-ERBB4:p-ERBB2:GRB2:SOS1 [plasma membrane] (Rattus norvegicus)
Phosphorylated ERBB2:ERBB4 heterodimers [plasma membrane] (Rattus norvegicus)
Phosphorylated ERBB2:ERBB4cyt1 heterodimers [plasma membrane] (Rattus norvegicus)
NRGs/EGFLs:p-ERBB4cyt1:p-6Y-ERBB2 [plasma membrane] (Rattus norvegicus)
Phosphorylated ERBB2:ERBB4 heterodimers [plasma membrane] (Rattus norvegicus)
Phosphorylated ERBB2:ERBB4cyt1 heterodimers [plasma membrane] (Rattus norvegicus)
NRGs/EGFLs:p-ERBB4cyt1:p-6Y-ERBB2 [plasma membrane] (Rattus norvegicus)
RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers (Rattus norvegicus)
NRGs/EGFLs:p-ERBB4:p-ERBB2:GRB2:SOS1 [plasma membrane] (Rattus norvegicus)
Phosphorylated ERBB2:ERBB4 heterodimers [plasma membrane] (Rattus norvegicus)
Phosphorylated ERBB2:ERBB4cyt1 heterodimers [plasma membrane] (Rattus norvegicus)
NRGs/EGFLs:p-ERBB4cyt1:p-6Y-ERBB2 [plasma membrane] (Rattus norvegicus)
PI3K events in ERBB2 signaling (Rattus norvegicus)
Binding of PI3K to p-ERBB2:p-ERBB4 CYT-1 heterodimers (Rattus norvegicus)
NRGs/EGFLs:p-ERBB4cyt1:p-ERBB2:PI3K [plasma membrane] (Rattus norvegicus)
Phosphorylated ERBB2:ERBB4cyt1 heterodimers [plasma membrane] (Rattus norvegicus)
NRGs/EGFLs:p-ERBB4cyt1:p-6Y-ERBB2 [plasma membrane] (Rattus norvegicus)
Phosphorylated ERBB2:ERBB4cyt1 heterodimers [plasma membrane] (Rattus norvegicus)
NRGs/EGFLs:p-ERBB4cyt1:p-6Y-ERBB2 [plasma membrane] (Rattus norvegicus)
PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB4 CYT1 (Rattus norvegicus)
NRGs/EGFLs:p-ERBB4cyt1:p-ERBB2:PI3K [plasma membrane] (Rattus norvegicus)
Phosphorylated ERBB2:ERBB4cyt1 heterodimers [plasma membrane] (Rattus norvegicus)
NRGs/EGFLs:p-ERBB4cyt1:p-6Y-ERBB2 [plasma membrane] (Rattus norvegicus)
SHC1 events in ERBB2 signaling (Rattus norvegicus)
SHC1 phosphorylation by ERBB2 heterodimers (Rattus norvegicus)
SHC1:Phosphorylated ERBB2 heterodimers [plasma membrane] (Rattus norvegicus)
p-ERBB2 heterodimers [plasma membrane] (Rattus norvegicus)
p-6Y-ERBB2 heterodimers [plasma membrane] (Rattus norvegicus)
NRGs/EGFLs:p-ERBB4:p-6Y-ERBB2 [plasma membrane] (Rattus norvegicus)
NRGs/EGFLs:p-ERBB4cyt1:p-6Y-ERBB2 [plasma membrane] (Rattus norvegicus)
p-Y349,350-SHC1:Phosphorylated ERBB2 heterodimers [plasma membrane] (Rattus norvegicus)
p-ERBB2 heterodimers [plasma membrane] (Rattus norvegicus)
p-6Y-ERBB2 heterodimers [plasma membrane] (Rattus norvegicus)
NRGs/EGFLs:p-ERBB4:p-6Y-ERBB2 [plasma membrane] (Rattus norvegicus)
NRGs/EGFLs:p-ERBB4cyt1:p-6Y-ERBB2 [plasma membrane] (Rattus norvegicus)
Trans-autophosphorylation of ERBB2 heterodimers (Rattus norvegicus)
p-6Y-ERBB2 heterodimers [plasma membrane] (Rattus norvegicus)
NRGs/EGFLs:p-ERBB4:p-6Y-ERBB2 [plasma membrane] (Rattus norvegicus)
NRGs/EGFLs:p-ERBB4cyt1:p-6Y-ERBB2 [plasma membrane] (Rattus norvegicus)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
NRGs/EGF-like ligands:p-ERBB4cyt1 [plasma membrane]
(Rattus norvegicus)
phospho-p-6Y-ERBB2 [plasma membrane]
(Rattus norvegicus)
Participates
as a member of
NRGs/EGFLs:p-ERBB4:p-6Y-ERBB2 [plasma membrane] (Rattus norvegicus)
Phosphorylated ERBB2:ERBB4cyt1 heterodimers [plasma membrane] (Rattus norvegicus)
Inferred From
NRGs/EGFLs:p-ERBB4cyt1:p-6Y-ERBB2 [plasma membrane]
(Homo sapiens)
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