Reactome | Sfn [cytosol]

Sfn [cytosol]

Stable Identifier

R-RNO-1445105

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

cytosol

Synonyms

SFN, G3V9A3

Locations in the PathwayBrowser

Expand all

Cell Cycle (Rattus norvegicus)

- Cell Cycle Checkpoints (Rattus norvegicus)
  - G2/M Checkpoints (Rattus norvegicus)
    - G2/M DNA damage checkpoint (Rattus norvegicus)
      - Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex (Rattus norvegicus)
        
        Association of p-S216-CDC25C with 14-3-3 proteins (Rattus norvegicus)
        
        14-3-3 dimer [cytosol] (Rattus norvegicus)
        
        SFN dimer [cytosol] (Rattus norvegicus)
        
        Sfn [cytosol] (Rattus norvegicus)
        
        p-S216-CDC25C:14-3-3 protein complex [cytosol] (Rattus norvegicus)
        
        14-3-3 dimer [cytosol] (Rattus norvegicus)
        
        SFN dimer [cytosol] (Rattus norvegicus)
        
        Sfn [cytosol] (Rattus norvegicus)

Programmed Cell Death (Rattus norvegicus)

- Apoptosis (Rattus norvegicus)
  - Intrinsic Pathway for Apoptosis (Rattus norvegicus)
    - Activation of BH3-only proteins (Rattus norvegicus)
      - Activation of BAD and translocation to mitochondria (Rattus norvegicus)
        
        Activation of BAD by calcineurin (Rattus norvegicus)
        
        14-3-3 dimer [cytosol] (Rattus norvegicus)
        
        SFN dimer [cytosol] (Rattus norvegicus)
        
        Sfn [cytosol] (Rattus norvegicus)
        
        14-3-3 proteins:p-S99-BAD complex [cytosol] (Rattus norvegicus)
        
        14-3-3 dimer [cytosol] (Rattus norvegicus)
        
        SFN dimer [cytosol] (Rattus norvegicus)
        
        Sfn [cytosol] (Rattus norvegicus)
        
        Sequestration of BAD protein by 14-3-3 (Rattus norvegicus)
        
        14-3-3 dimer [cytosol] (Rattus norvegicus)
        
        SFN dimer [cytosol] (Rattus norvegicus)
        
        Sfn [cytosol] (Rattus norvegicus)
        
        14-3-3 proteins:p-S99-BAD complex [cytosol] (Rattus norvegicus)
        
        14-3-3 dimer [cytosol] (Rattus norvegicus)
        
        SFN dimer [cytosol] (Rattus norvegicus)
        
        Sfn [cytosol] (Rattus norvegicus)

Signal Transduction (Rattus norvegicus)

- Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Rattus norvegicus)
  - Signaling by Rho GTPases (Rattus norvegicus)
    - RHO GTPase Effectors (Rattus norvegicus)
      - RHO GTPases activate PKNs (Rattus norvegicus)
        
        Association of p-S216-CDC25C with 14-3-3 proteins (Rattus norvegicus)
        
        14-3-3 dimer [cytosol] (Rattus norvegicus)
        
        SFN dimer [cytosol] (Rattus norvegicus)
        
        Sfn [cytosol] (Rattus norvegicus)
        
        p-S216-CDC25C:14-3-3 protein complex [cytosol] (Rattus norvegicus)
        
        14-3-3 dimer [cytosol] (Rattus norvegicus)
        
        SFN dimer [cytosol] (Rattus norvegicus)
        
        Sfn [cytosol] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:G3V9A3

Gene Names

Sfn

Reference Genes

ENSEMBL:ENSRNOG00000033153

ENSEMBL:ENSRNOG00000033153.5 Sfn

Reference Transcript

Other Identifiers

10872572

1374306_at

1374806_at

1375096_at

17802702

5690671

5841473

5897780

6031635

6087280

6383563

6390149

6444755

6450602

6475816

6523037

6710515

A_44_P915168

A_44_P958894

A_64_P006354

GE1120624

GE18475

ILMN_1352207

PH_rn_0023815

Participates

as an input of

SFN dimerizes (Rattus norvegicus)

as a component of

SFN dimer [cytosol] (Rattus norvegicus)

Inferred From

SFN [cytosol] (Homo sapiens)

Cross References

RefSeq

XP_003750096.1, XP_001065560.2

Ensembl

ENSRNOP00000040819, ENSRNOG00000033153, ENSRNOT00000043959

RGD

1304729

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