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Active mTORC1 complex [lysosomal membrane]
Stable Identifier
R-RNO-165678
Type
Complex
Species
Rattus norvegicus
Compartment
lysosomal membrane
Locations in the PathwayBrowser
Expand all
Autophagy (Rattus norvegicus)
Macroautophagy (Rattus norvegicus)
Active MTORC1 binds the ULK1 complex (Rattus norvegicus)
Active mTORC1 complex [lysosomal membrane] (Rattus norvegicus)
MTORC1:RHEB:GTP:ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Rattus norvegicus)
Active mTORC1 complex [lysosomal membrane] (Rattus norvegicus)
Active MTORC1 phosphorylates ULK1 (Rattus norvegicus)
MTORC1:RHEB:GTP:ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Rattus norvegicus)
Active mTORC1 complex [lysosomal membrane] (Rattus norvegicus)
MTORC1:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Rattus norvegicus)
Active mTORC1 complex [lysosomal membrane] (Rattus norvegicus)
Rheb in the MTORC1 complex hydrolyses GTP (Rattus norvegicus)
Active mTORC1 complex [lysosomal membrane] (Rattus norvegicus)
p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex (Rattus norvegicus)
MTORC1:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Rattus norvegicus)
Active mTORC1 complex [lysosomal membrane] (Rattus norvegicus)
Gene expression (Transcription) (Rattus norvegicus)
RNA Polymerase II Transcription (Rattus norvegicus)
Generic Transcription Pathway (Rattus norvegicus)
Transcriptional Regulation by TP53 (Rattus norvegicus)
TP53 Regulates Metabolic Genes (Rattus norvegicus)
RHEB in mTORC1:RHEB:GTP hydrolyses GTP (Rattus norvegicus)
Active mTORC1 complex [lysosomal membrane] (Rattus norvegicus)
Signal Transduction (Rattus norvegicus)
Intracellular signaling by second messengers (Rattus norvegicus)
PIP3 activates AKT signaling (Rattus norvegicus)
PTEN Regulation (Rattus norvegicus)
Regulation of PTEN gene transcription (Rattus norvegicus)
MAF1 translocates to the nucleus (Rattus norvegicus)
Active mTORC1 complex [lysosomal membrane] (Rattus norvegicus)
mTORC1 phosphorylates MAF1 (Rattus norvegicus)
Active mTORC1 complex [lysosomal membrane] (Rattus norvegicus)
MTOR signalling (Rattus norvegicus)
AKT1S1 (PRAS40) binds mTORC1 (Rattus norvegicus)
Active mTORC1 complex [lysosomal membrane] (Rattus norvegicus)
mTORC1:RHEB:GTP:AKT1S1 [lysosomal membrane] (Rattus norvegicus)
Active mTORC1 complex [lysosomal membrane] (Rattus norvegicus)
Activated Akt1 phosphorylates AKT1S1 (PRAS40) (Rattus norvegicus)
mTORC1:RHEB:GTP:AKT1S1 [lysosomal membrane] (Rattus norvegicus)
Active mTORC1 complex [lysosomal membrane] (Rattus norvegicus)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Rattus norvegicus)
Active mTORC1 complex [lysosomal membrane] (Rattus norvegicus)
Energy dependent regulation of mTOR by LKB1-AMPK (Rattus norvegicus)
AMPK phosphorylates Raptor in the mTORC1 complex (Rattus norvegicus)
Active mTORC1 complex [lysosomal membrane] (Rattus norvegicus)
RHEB in mTORC1:RHEB:GTP hydrolyses GTP (Rattus norvegicus)
Active mTORC1 complex [lysosomal membrane] (Rattus norvegicus)
Formation of active mTORC1 complex (Rattus norvegicus)
Active mTORC1 complex [lysosomal membrane] (Rattus norvegicus)
Phosphorylated AKT1S1:mTORC1 binds YWHAB (Rattus norvegicus)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Rattus norvegicus)
Active mTORC1 complex [lysosomal membrane] (Rattus norvegicus)
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Rattus norvegicus)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Rattus norvegicus)
Active mTORC1 complex [lysosomal membrane] (Rattus norvegicus)
mTORC1 phosphorylates AKT1S1 (Rattus norvegicus)
mTORC1:RHEB:GTP:p-S183,T246-AKT1S1:YWHAB [lysosomal membrane] (Rattus norvegicus)
mTORC1:RHEB:GTP:p-S183,T246-AKT1S1 [lysosomal membrane] (Rattus norvegicus)
Active mTORC1 complex [lysosomal membrane] (Rattus norvegicus)
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Rattus norvegicus)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Rattus norvegicus)
Active mTORC1 complex [lysosomal membrane] (Rattus norvegicus)
mTORC1-mediated signalling (Rattus norvegicus)
Phosphorylation of 4E-BP1 by activated mTORC1 (Rattus norvegicus)
Active mTORC1 complex [lysosomal membrane] (Rattus norvegicus)
mTORC1:RHEB:GTP:AKT1S1 [lysosomal membrane] (Rattus norvegicus)
Active mTORC1 complex [lysosomal membrane] (Rattus norvegicus)
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Rattus norvegicus)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Rattus norvegicus)
Active mTORC1 complex [lysosomal membrane] (Rattus norvegicus)
mTORC1 phosphorylation of RPS6KB1 (S6K) (Rattus norvegicus)
Active mTORC1 complex [lysosomal membrane] (Rattus norvegicus)
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Rattus norvegicus)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Rattus norvegicus)
Active mTORC1 complex [lysosomal membrane] (Rattus norvegicus)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane]
(Rattus norvegicus)
RHEB:GTP [lysosomal membrane]
(Rattus norvegicus)
Participates
as an input of
AKT1S1 (PRAS40) binds mTORC1 (Rattus norvegicus)
AMPK phosphorylates Raptor in the mTORC1 complex (Rattus norvegicus)
Rheb in the MTORC1 complex hydrolyses GTP (Rattus norvegicus)
RHEB in mTORC1:RHEB:GTP hydrolyses GTP (Rattus norvegicus)
Active MTORC1 binds the ULK1 complex (Rattus norvegicus)
as a component of
mTORC1:RHEB:GTP:p-S183,T246-AKT1S1 [lysosomal membrane] (Rattus norvegicus)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Rattus norvegicus)
mTORC1:RHEB:GTP:AKT1S1 [lysosomal membrane] (Rattus norvegicus)
MTORC1:RHEB:GTP:ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Rattus norvegicus)
MTORC1:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Rattus norvegicus)
as an output of
Formation of active mTORC1 complex (Rattus norvegicus)
This entity regulates
Negatively
MAF1 translocates to the nucleus
(Rattus norvegicus)
Inferred From
Active mTORC1 complex [lysosomal membrane]
(Homo sapiens)
MTORC1:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane]
(Homo sapiens)
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