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TGFBR2 [plasma membrane]
Stable Identifier
R-RNO-170842
Type
Protein [EntityWithAccessionedSequence]
Species
Rattus norvegicus
Compartment
plasma membrane
Synonyms
P38438
Locations in the PathwayBrowser
Expand all
Signal Transduction (Rattus norvegicus)
Signaling by TGFB family members (Rattus norvegicus)
Signaling by TGF-beta Receptor Complex (Rattus norvegicus)
TGF-beta receptor signaling activates SMADs (Rattus norvegicus)
Activated type I receptor phosphorylates SMAD2/3 directly (Rattus norvegicus)
TGFB1:p-TGFBR:ZFYVE9:SMAD2/3 [early endosome membrane] (Rattus norvegicus)
TGFBR2 homodimer [plasma membrane] (Rattus norvegicus)
TGFBR2 [plasma membrane] (Rattus norvegicus)
TGFB1:p-TGFBR:ZFYVE9:p-2S-SMAD2,3 [early endosome membrane] (Rattus norvegicus)
TGFBR2 homodimer [plasma membrane] (Rattus norvegicus)
TGFBR2 [plasma membrane] (Rattus norvegicus)
An anchoring protein, ZFYVE9 (SARA), recruits SMAD2/3 (Rattus norvegicus)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Rattus norvegicus)
TGFBR2 homodimer [plasma membrane] (Rattus norvegicus)
TGFBR2 [plasma membrane] (Rattus norvegicus)
TGFB1:p-TGFBR:ZFYVE9:SMAD2/3 [early endosome membrane] (Rattus norvegicus)
TGFBR2 homodimer [plasma membrane] (Rattus norvegicus)
TGFBR2 [plasma membrane] (Rattus norvegicus)
CBL binds TGFBR2 (Rattus norvegicus)
TGFBR2 [plasma membrane] (Rattus norvegicus)
TGFBR2:CBL [plasma membrane] (Rattus norvegicus)
TGFBR2 [plasma membrane] (Rattus norvegicus)
CBL neddylates TGFBR2 (Rattus norvegicus)
TGFBR2:CBL [plasma membrane] (Rattus norvegicus)
TGFBR2 [plasma membrane] (Rattus norvegicus)
Dimeric TGF-beta-1 binds to the receptor (Rattus norvegicus)
Dimeric TGFB1:TGFBR2 homodimer [plasma membrane] (Rattus norvegicus)
TGFBR2 homodimer [plasma membrane] (Rattus norvegicus)
TGFBR2 [plasma membrane] (Rattus norvegicus)
TGFB1,TGFB2:TGFBR3:TGFBR2 [plasma membrane] (Rattus norvegicus)
TGFBR2 [plasma membrane] (Rattus norvegicus)
TGFBR2 [plasma membrane] (Rattus norvegicus)
Downregulation of TGF-beta receptor signaling (Rattus norvegicus)
BAMBI interferes with the interaction of type I receptor with type II receptor (Rattus norvegicus)
TGFB1: TGFBR2: p-TGFBR1: BAMBI: SMAD7 [plasma membrane] (Rattus norvegicus)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Rattus norvegicus)
TGFBR2 homodimer [plasma membrane] (Rattus norvegicus)
TGFBR2 [plasma membrane] (Rattus norvegicus)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Rattus norvegicus)
TGFBR2 homodimer [plasma membrane] (Rattus norvegicus)
TGFBR2 [plasma membrane] (Rattus norvegicus)
Degradation of TGF-beta receptor complex (Rattus norvegicus)
TGFB1:TGFBR2:Ub-p-TGFBR1:Ub-SMAD7 [plasma membrane] (Rattus norvegicus)
TGFB1: p-TGFBR: I-SMAD7 [plasma membrane] (Rattus norvegicus)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Rattus norvegicus)
TGFBR2 homodimer [plasma membrane] (Rattus norvegicus)
TGFBR2 [plasma membrane] (Rattus norvegicus)
I-SMAD competes with SMAD2/3 for type I receptor (TGFBR1) (Rattus norvegicus)
TGFB1: p-TGFBR: I-SMAD7 [plasma membrane] (Rattus norvegicus)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Rattus norvegicus)
TGFBR2 homodimer [plasma membrane] (Rattus norvegicus)
TGFBR2 [plasma membrane] (Rattus norvegicus)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Rattus norvegicus)
TGFBR2 homodimer [plasma membrane] (Rattus norvegicus)
TGFBR2 [plasma membrane] (Rattus norvegicus)
STRAP stabilizes interaction of activated TGF-beta receptor complex with SMAD7 (Rattus norvegicus)
TGFB1: p-TGFBR: STRAP: SMAD7 [plasma membrane] (Rattus norvegicus)
TGFB1:p-TGFBR:STRAP [plasma membrane] (Rattus norvegicus)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Rattus norvegicus)
TGFBR2 homodimer [plasma membrane] (Rattus norvegicus)
TGFBR2 [plasma membrane] (Rattus norvegicus)
TGFB1:p-TGFBR:STRAP [plasma membrane] (Rattus norvegicus)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Rattus norvegicus)
TGFBR2 homodimer [plasma membrane] (Rattus norvegicus)
TGFBR2 [plasma membrane] (Rattus norvegicus)
Phosphorylated SMAD2/3 dissociates from TGFBR (Rattus norvegicus)
TGFB1:p-TGFBR:ZFYVE9 [early endosome membrane] (Rattus norvegicus)
TGFBR2 homodimer [plasma membrane] (Rattus norvegicus)
TGFBR2 [plasma membrane] (Rattus norvegicus)
TGFB1:p-TGFBR:ZFYVE9:p-2S-SMAD2,3 [early endosome membrane] (Rattus norvegicus)
TGFBR2 homodimer [plasma membrane] (Rattus norvegicus)
TGFBR2 [plasma membrane] (Rattus norvegicus)
TGFBR2 phosphorylates TGFBR1 (Rattus norvegicus)
TGFB1:TGFBR2:TGFBR1 [plasma membrane] (Rattus norvegicus)
TGFBR2 homodimer [plasma membrane] (Rattus norvegicus)
TGFBR2 [plasma membrane] (Rattus norvegicus)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Rattus norvegicus)
TGFBR2 homodimer [plasma membrane] (Rattus norvegicus)
TGFBR2 [plasma membrane] (Rattus norvegicus)
TGFBR2 homodimer [plasma membrane] (Rattus norvegicus)
TGFBR2 [plasma membrane] (Rattus norvegicus)
TGFBR2 recruits TGFBR1 (Rattus norvegicus)
Dimeric TGFB1:TGFBR2 homodimer [plasma membrane] (Rattus norvegicus)
TGFBR2 homodimer [plasma membrane] (Rattus norvegicus)
TGFBR2 [plasma membrane] (Rattus norvegicus)
TGFB1,TGFB2:TGFBR3:TGFBR2 [plasma membrane] (Rattus norvegicus)
TGFBR2 [plasma membrane] (Rattus norvegicus)
TGFB1:TGFBR2:TGFBR1 [plasma membrane] (Rattus norvegicus)
TGFBR2 homodimer [plasma membrane] (Rattus norvegicus)
TGFBR2 [plasma membrane] (Rattus norvegicus)
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) (Rattus norvegicus)
Disassembly of tight junctions (Rattus norvegicus)
Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:Ub-RHOA:SMURF1 [cell junction] (Rattus norvegicus)
Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA:SMURF1 [plasma membrane] (Rattus norvegicus)
Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA [cell junction] (Rattus norvegicus)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Rattus norvegicus)
TGFBR2 homodimer [plasma membrane] (Rattus norvegicus)
TGFBR2 [plasma membrane] (Rattus norvegicus)
SMURF1 binds phosphorylated PARD6A (Rattus norvegicus)
Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA [cell junction] (Rattus norvegicus)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Rattus norvegicus)
TGFBR2 homodimer [plasma membrane] (Rattus norvegicus)
TGFBR2 [plasma membrane] (Rattus norvegicus)
Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA:SMURF1 [plasma membrane] (Rattus norvegicus)
Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA [cell junction] (Rattus norvegicus)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Rattus norvegicus)
TGFBR2 homodimer [plasma membrane] (Rattus norvegicus)
TGFBR2 [plasma membrane] (Rattus norvegicus)
SMURF1 ubiquitinates RHOA (Rattus norvegicus)
Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA:SMURF1 [plasma membrane] (Rattus norvegicus)
Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA [cell junction] (Rattus norvegicus)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Rattus norvegicus)
TGFBR2 homodimer [plasma membrane] (Rattus norvegicus)
TGFBR2 [plasma membrane] (Rattus norvegicus)
Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:Ub-RHOA:SMURF1 [cell junction] (Rattus norvegicus)
Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA:SMURF1 [plasma membrane] (Rattus norvegicus)
Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA [cell junction] (Rattus norvegicus)
TGFB1:TGFBR2:p-TGFBR1 [plasma membrane] (Rattus norvegicus)
TGFBR2 homodimer [plasma membrane] (Rattus norvegicus)
TGFBR2 [plasma membrane] (Rattus norvegicus)
External Reference Information
External Reference
UniProt:P38438
Reference Genes
BioGPS Gene:81810
ENSEMBL:ENSRNOG00000013265
ENSEMBL:ENSRNOG00000013265.7
ENSEMBL:ENSRNOG00055006638
ENSEMBL:ENSRNOG00060030566
ENSEMBL:ENSRNOG00065003711
KEGG Gene (Rattus norvegicus):81810
Monarch:81810
NCBI Gene:81810
UCSC:P38438
Reference Transcript
RefSeq:NM_031132.3
Other Identifiers
10920743
10920745
1369653_at
1372466_at
17856251
5742258
5880076
6028047
6033267
6132456
6209648
6329564
6381459
6605969
6632360
6692136
81810
A_43_P12533
A_44_P697615
A_64_P129315
GE1188996
GE21678
GO:0003824
GO:0004672
GO:0004674
GO:0004675
GO:0005026
GO:0005524
GO:0006468
GO:0007178
GO:0016020
GO:0016740
GO:0023052
GO:0036211
GO:0038023
GO:0043235
GO:0046872
GO:0060089
GO:0140096
ILMN_1371159
L09653_s_at
rc_AI010354_at
Participates
as an input of
CBL binds TGFBR2 (Rattus norvegicus)
Dimeric TGF-beta-1 binds to the receptor (Rattus norvegicus)
as a component of
TGFBR2:CBL [plasma membrane] (Rattus norvegicus)
TGFB1,TGFB2:TGFBR3:TGFBR2 [plasma membrane] (Rattus norvegicus)
TGFBR2 homodimer [plasma membrane] (Rattus norvegicus)
Other forms of this molecule
NEDD8-K556,K567-TGFBR2 [plasma membrane]
Inferred From
TGFBR2 [plasma membrane]
(Homo sapiens)
Cross References
RefSeq
NP_112394.3
Ensembl
ENSRNOT00000116107
,
ENSRNOG00000013265
,
ENSRNOP00000093892
PRO
P38438
RGD
69651
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