Reactome | Apob [plasma membrane]

Apob [plasma membrane]

Stable Identifier

R-RNO-171089

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

plasma membrane

Synonyms

APOB(28-4563), Q7TMA5

Locations in the PathwayBrowser

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Vesicle-mediated transport (Rattus norvegicus)

- Membrane Trafficking (Rattus norvegicus)
  - Clathrin-mediated endocytosis (Rattus norvegicus)
    - Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle (Rattus norvegicus)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
        
        DAB2,LDLRAP1:LDLR:LDL [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
        
        LDL:LDLR complex [plasma membrane] (Rattus norvegicus)
        
        LDL [plasma membrane] (Rattus norvegicus)
        
        Apob [plasma membrane] (Rattus norvegicus)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
        
        DAB2,LDLRAP1:LDLR:LDL [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
        
        LDL:LDLR complex [plasma membrane] (Rattus norvegicus)
        
        LDL [plasma membrane] (Rattus norvegicus)
        
        Apob [plasma membrane] (Rattus norvegicus)
    - BAR domain proteins recruit dynamin (Rattus norvegicus)
      - PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Rattus norvegicus)
        
        PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Rattus norvegicus)
        
        PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Rattus norvegicus)
        
        CLASP proteins:cargo [plasma membrane] (Rattus norvegicus)
        
        DAB2,LDLRAP1:LDLR:LDL [plasma membrane] (Rattus norvegicus)
        
        LDL:LDLR complex [plasma membrane] (Rattus norvegicus)
        
        LDL [plasma membrane] (Rattus norvegicus)
        
        Apob [plasma membrane] (Rattus norvegicus)
      - PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Rattus norvegicus)
        
        PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Rattus norvegicus)
        
        PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Rattus norvegicus)
        
        PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Rattus norvegicus)
        
        CLASP proteins:cargo [plasma membrane] (Rattus norvegicus)
        
        DAB2,LDLRAP1:LDLR:LDL [plasma membrane] (Rattus norvegicus)
        
        LDL:LDLR complex [plasma membrane] (Rattus norvegicus)
        
        LDL [plasma membrane] (Rattus norvegicus)
        
        Apob [plasma membrane] (Rattus norvegicus)
    - CLASP proteins and cargo are recruited to the nascent clathrin-coated pit (Rattus norvegicus)
      - CLASP proteins:cargo [plasma membrane] (Rattus norvegicus)
        
        DAB2,LDLRAP1:LDLR:LDL [plasma membrane] (Rattus norvegicus)
        
        LDL:LDLR complex [plasma membrane] (Rattus norvegicus)
        
        LDL [plasma membrane] (Rattus norvegicus)
        
        Apob [plasma membrane] (Rattus norvegicus)
      - PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Rattus norvegicus)
        
        CLASP proteins:cargo [plasma membrane] (Rattus norvegicus)
        
        DAB2,LDLRAP1:LDLR:LDL [plasma membrane] (Rattus norvegicus)
        
        LDL:LDLR complex [plasma membrane] (Rattus norvegicus)
        
        LDL [plasma membrane] (Rattus norvegicus)
        
        Apob [plasma membrane] (Rattus norvegicus)
    - Cargo recognition for clathrin-mediated endocytosis (Rattus norvegicus)
      - LDLR is bound by DAB2 and ARH (Rattus norvegicus)
        
        DAB2,LDLRAP1:LDLR:LDL [plasma membrane] (Rattus norvegicus)
        
        LDL:LDLR complex [plasma membrane] (Rattus norvegicus)
        
        LDL [plasma membrane] (Rattus norvegicus)
        
        Apob [plasma membrane] (Rattus norvegicus)
        
        LDL:LDLR complex [plasma membrane] (Rattus norvegicus)
        
        LDL [plasma membrane] (Rattus norvegicus)
        
        Apob [plasma membrane] (Rattus norvegicus)
    - Clathrin recruits PIK3C2A (Rattus norvegicus)
      - PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Rattus norvegicus)
        
        CLASP proteins:cargo [plasma membrane] (Rattus norvegicus)
        
        DAB2,LDLRAP1:LDLR:LDL [plasma membrane] (Rattus norvegicus)
        
        LDL:LDLR complex [plasma membrane] (Rattus norvegicus)
        
        LDL [plasma membrane] (Rattus norvegicus)
        
        Apob [plasma membrane] (Rattus norvegicus)
      - PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Rattus norvegicus)
        
        PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Rattus norvegicus)
        
        CLASP proteins:cargo [plasma membrane] (Rattus norvegicus)
        
        DAB2,LDLRAP1:LDLR:LDL [plasma membrane] (Rattus norvegicus)
        
        LDL:LDLR complex [plasma membrane] (Rattus norvegicus)
        
        LDL [plasma membrane] (Rattus norvegicus)
        
        Apob [plasma membrane] (Rattus norvegicus)
    - Clathrin recruits auxilins to the clathrin-coated vesicle (Rattus norvegicus)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
        
        DAB2,LDLRAP1:LDLR:LDL [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
        
        LDL:LDLR complex [plasma membrane] (Rattus norvegicus)
        
        LDL [plasma membrane] (Rattus norvegicus)
        
        Apob [plasma membrane] (Rattus norvegicus)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
        
        DAB2,LDLRAP1:LDLR:LDL [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
        
        LDL:LDLR complex [plasma membrane] (Rattus norvegicus)
        
        LDL [plasma membrane] (Rattus norvegicus)
        
        Apob [plasma membrane] (Rattus norvegicus)
    - Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 (Rattus norvegicus)
      - PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Rattus norvegicus)
        
        PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Rattus norvegicus)
        
        CLASP proteins:cargo [plasma membrane] (Rattus norvegicus)
        
        DAB2,LDLRAP1:LDLR:LDL [plasma membrane] (Rattus norvegicus)
        
        LDL:LDLR complex [plasma membrane] (Rattus norvegicus)
        
        LDL [plasma membrane] (Rattus norvegicus)
        
        Apob [plasma membrane] (Rattus norvegicus)
    - Dissociation of AAK1 and dephosphorylation of AP-2 mu2 (Rattus norvegicus)
      - PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
        
        PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
        
        DAB2,LDLRAP1:LDLR:LDL [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
        
        LDL:LDLR complex [plasma membrane] (Rattus norvegicus)
        
        LDL [plasma membrane] (Rattus norvegicus)
        
        Apob [plasma membrane] (Rattus norvegicus)
      - PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilinGGC-RAB5:GTP:GAPVD1 [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
        
        PI(4)P:ITSNs:EPS15:REPS1:NECAPs:AP-2:SGIP1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
        
        DAB2,LDLRAP1:LDLR:LDL [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
        
        LDL:LDLR complex [plasma membrane] (Rattus norvegicus)
        
        LDL [plasma membrane] (Rattus norvegicus)
        
        Apob [plasma membrane] (Rattus norvegicus)
    - Dynamin-mediated GTP hydrolysis promotes vesicle scission (Rattus norvegicus)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
        
        DAB2,LDLRAP1:LDLR:LDL [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
        
        LDL:LDLR complex [plasma membrane] (Rattus norvegicus)
        
        LDL [plasma membrane] (Rattus norvegicus)
        
        Apob [plasma membrane] (Rattus norvegicus)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Rattus norvegicus)
        
        CLASP proteins:cargo [plasma membrane] (Rattus norvegicus)
        
        DAB2,LDLRAP1:LDLR:LDL [plasma membrane] (Rattus norvegicus)
        
        LDL:LDLR complex [plasma membrane] (Rattus norvegicus)
        
        LDL [plasma membrane] (Rattus norvegicus)
        
        Apob [plasma membrane] (Rattus norvegicus)
    - Endophilins recruit synaptojanins to the clathrin-coated pit (Rattus norvegicus)
      - PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Rattus norvegicus)
        
        PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Rattus norvegicus)
        
        PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Rattus norvegicus)
        
        PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Rattus norvegicus)
        
        CLASP proteins:cargo [plasma membrane] (Rattus norvegicus)
        
        DAB2,LDLRAP1:LDLR:LDL [plasma membrane] (Rattus norvegicus)
        
        LDL:LDLR complex [plasma membrane] (Rattus norvegicus)
        
        LDL [plasma membrane] (Rattus norvegicus)
        
        Apob [plasma membrane] (Rattus norvegicus)
      - PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Rattus norvegicus)
        
        PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Rattus norvegicus)
        
        PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Rattus norvegicus)
        
        PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Rattus norvegicus)
        
        PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Rattus norvegicus)
        
        CLASP proteins:cargo [plasma membrane] (Rattus norvegicus)
        
        DAB2,LDLRAP1:LDLR:LDL [plasma membrane] (Rattus norvegicus)
        
        LDL:LDLR complex [plasma membrane] (Rattus norvegicus)
        
        LDL [plasma membrane] (Rattus norvegicus)
        
        Apob [plasma membrane] (Rattus norvegicus)
    - F- and N- BAR domain proteins bind the clathrin-coated pit (Rattus norvegicus)
      - PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Rattus norvegicus)
        
        PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Rattus norvegicus)
        
        CLASP proteins:cargo [plasma membrane] (Rattus norvegicus)
        
        DAB2,LDLRAP1:LDLR:LDL [plasma membrane] (Rattus norvegicus)
        
        LDL:LDLR complex [plasma membrane] (Rattus norvegicus)
        
        LDL [plasma membrane] (Rattus norvegicus)
        
        Apob [plasma membrane] (Rattus norvegicus)
      - PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Rattus norvegicus)
        
        PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Rattus norvegicus)
        
        CLASP proteins:cargo [plasma membrane] (Rattus norvegicus)
        
        DAB2,LDLRAP1:LDLR:LDL [plasma membrane] (Rattus norvegicus)
        
        LDL:LDLR complex [plasma membrane] (Rattus norvegicus)
        
        LDL [plasma membrane] (Rattus norvegicus)
        
        Apob [plasma membrane] (Rattus norvegicus)
    - HSPA8-mediated ATP hydrolysis promotes vesicle uncoating (Rattus norvegicus)
      - PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
        
        DAB2,LDLRAP1:LDLR:LDL [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
        
        LDL:LDLR complex [plasma membrane] (Rattus norvegicus)
        
        LDL [plasma membrane] (Rattus norvegicus)
        
        Apob [plasma membrane] (Rattus norvegicus)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
        
        DAB2,LDLRAP1:LDLR:LDL [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
        
        LDL:LDLR complex [plasma membrane] (Rattus norvegicus)
        
        LDL [plasma membrane] (Rattus norvegicus)
        
        Apob [plasma membrane] (Rattus norvegicus)
    - RAB5 and GAPVD1 bind AP-2 (Rattus norvegicus)
      - PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
        
        PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
        
        DAB2,LDLRAP1:LDLR:LDL [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
        
        LDL:LDLR complex [plasma membrane] (Rattus norvegicus)
        
        LDL [plasma membrane] (Rattus norvegicus)
        
        Apob [plasma membrane] (Rattus norvegicus)
    - SYNJ hydrolyze PI(4,5)P2 to PI(4)P (Rattus norvegicus)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Rattus norvegicus)
        
        CLASP proteins:cargo [plasma membrane] (Rattus norvegicus)
        
        DAB2,LDLRAP1:LDLR:LDL [plasma membrane] (Rattus norvegicus)
        
        LDL:LDLR complex [plasma membrane] (Rattus norvegicus)
        
        LDL [plasma membrane] (Rattus norvegicus)
        
        Apob [plasma membrane] (Rattus norvegicus)
      - PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Rattus norvegicus)
        
        PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Rattus norvegicus)
        
        PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Rattus norvegicus)
        
        PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Rattus norvegicus)
        
        PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Rattus norvegicus)
        
        CLASP proteins:cargo [plasma membrane] (Rattus norvegicus)
        
        DAB2,LDLRAP1:LDLR:LDL [plasma membrane] (Rattus norvegicus)
        
        LDL:LDLR complex [plasma membrane] (Rattus norvegicus)
        
        LDL [plasma membrane] (Rattus norvegicus)
        
        Apob [plasma membrane] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:Q7TMA5

Gene Names

Apob

Reference Genes

BioGPS Gene:54225 Apob

ENSEMBL:ENSRNOG00000005542

KEGG:rno:54225 Apob

Monarch:54225 Apob

NCBI Gene:54225 Apob

UCSC:Q7TMA5 Apob

Reference Transcript

RefSeq:NM_019287.2 Apob

Participates

as a component of

LDL [plasma membrane] (Rattus norvegicus)

Other forms of this molecule

Apob [cytosol]

Apob [early endosome]

Apob [lysosomal lumen]

Apob [clathrin-coated endocytic vesicle membrane]

Apob [endosome lumen]

Apob [endosome membrane]

Apob [clathrin-coated endocytic vesicle membrane]

Apob [extracellular region]

Apob [endoplasmic reticulum membrane]

phospho-Apob [endoplasmic reticulum lumen]

Apob [extracellular region]

Apob [endocytic vesicle lumen]

Apob [smooth endoplasmic reticulum]

Apob [endoplasmic reticulum membrane]

Apob [extracellular region]

Apob [endoplasmic reticulum lumen]

Apob [plasma membrane]

Inferred From

APOB(28-4563) [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_062160.2

PRO

Q7TMA5

RGD

2129

GlyGen

Q7TMA5

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P04639	10	Apoa1 [secretory granule lumen] (R-RNO-350761) Apoa1 [cytosol] (R-RNO-2395781) Apoa1 [early endosome] (R-RNO-2429641) Apoa1 [endoplasmic reticulum lumen] (R-RNO-174640) Apoa1 [extracellular region] (R-RNO-264771) Apoa1 [plasma membrane] (R-RNO-216742) Apoa1 [endocytic vesicle lumen] (R-RNO-2239460) phospho-Apoa1 [endoplasmic reticulum lumen] (R-RNO-8957081) Apoa1 [endoplasmic reticulum lumen] (R-RNO-8956724) Apoa1 [extracellular region] (R-RNO-174720)	0.544	2

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