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About
What is Reactome ?
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Release Calendar
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Privacy Notice
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Digital Preservation
Contact us
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Cdc26 [cytosol]
Stable Identifier
R-RNO-174052
Type
Protein [EntityWithAccessionedSequence]
Species
Rattus norvegicus
Compartment
cytosol
Synonyms
CDC26, Q6YDN7
Locations in the PathwayBrowser
Expand all
Cell Cycle (Rattus norvegicus)
Cell Cycle Checkpoints (Rattus norvegicus)
Mitotic Spindle Checkpoint (Rattus norvegicus)
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components (Rattus norvegicus)
Inactivation of APC/C via direct inhibition of the APC/C complex (Rattus norvegicus)
Binding of the MCC complex to the APC/C complex (Rattus norvegicus)
MCC:APC/C complex [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Cdc26 [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Cdc26 [cytosol] (Rattus norvegicus)
Cell Cycle, Mitotic (Rattus norvegicus)
M Phase (Rattus norvegicus)
Mitotic Metaphase and Anaphase (Rattus norvegicus)
Mitotic Anaphase (Rattus norvegicus)
Separation of Sister Chromatids (Rattus norvegicus)
Association of Securin with Cdc20:APC/C complex (Rattus norvegicus)
CDC20:p-APC/C [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Cdc26 [cytosol] (Rattus norvegicus)
CDC20:p-APC/C:PTTG1 [cytosol] (Rattus norvegicus)
CDC20:p-APC/C [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Cdc26 [cytosol] (Rattus norvegicus)
Degradation of multiubiquitinated Securin (Rattus norvegicus)
CDC20:p-APC/C [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Cdc26 [cytosol] (Rattus norvegicus)
CDC20:pAPC/C:K11polyUb-PTTG1 [cytosol] (Rattus norvegicus)
CDC20:p-APC/C [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Cdc26 [cytosol] (Rattus norvegicus)
Ubiquitination of Securin by phospho-APC/C:Cdc20 complex (Rattus norvegicus)
CDC20:p-APC/C:PTTG1 [cytosol] (Rattus norvegicus)
CDC20:p-APC/C [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Cdc26 [cytosol] (Rattus norvegicus)
CDC20:pAPC/C:K11polyUb-PTTG1 [cytosol] (Rattus norvegicus)
CDC20:p-APC/C [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Cdc26 [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Cdc26 [cytosol] (Rattus norvegicus)
Regulation of mitotic cell cycle (Rattus norvegicus)
APC/C-mediated degradation of cell cycle proteins (Rattus norvegicus)
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 (Rattus norvegicus)
Association of cell cycle proteins with the APC/C:Cdh1 complex (Rattus norvegicus)
cell cycle proteins:phospho-APC/C:Cdh1 complex [cytosol] (Rattus norvegicus)
phospho-APC/C:Cdh1 complex [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Cdc26 [cytosol] (Rattus norvegicus)
phospho-APC/C:Cdh1 complex [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Cdc26 [cytosol] (Rattus norvegicus)
Degradation of multiubiquitinated cell cycle proteins (Rattus norvegicus)
multiubiquitinated cell cycle protein:APC/C:Cdh1 complex [cytosol] (Rattus norvegicus)
cell cycle proteins:phospho-APC/C:Cdh1 complex [cytosol] (Rattus norvegicus)
phospho-APC/C:Cdh1 complex [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Cdc26 [cytosol] (Rattus norvegicus)
phospho-APC/C:Cdh1 complex [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Cdc26 [cytosol] (Rattus norvegicus)
Ubiquitination of cell cycle proteins targeted by the APC/C:Cdh1complex (Rattus norvegicus)
cell cycle proteins:phospho-APC/C:Cdh1 complex [cytosol] (Rattus norvegicus)
phospho-APC/C:Cdh1 complex [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Cdc26 [cytosol] (Rattus norvegicus)
multiubiquitinated cell cycle protein:APC/C:Cdh1 complex [cytosol] (Rattus norvegicus)
cell cycle proteins:phospho-APC/C:Cdh1 complex [cytosol] (Rattus norvegicus)
phospho-APC/C:Cdh1 complex [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Cdc26 [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Cdc26 [cytosol] (Rattus norvegicus)
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins (Rattus norvegicus)
APC/C:Cdc20 mediated degradation of mitotic proteins (Rattus norvegicus)
APC/C:Cdc20 mediated degradation of Cyclin B (Rattus norvegicus)
Association of Cyclin B:Cdc2 with Cdc20:APC/C complex (Rattus norvegicus)
CDC20:p-APC/C [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Cdc26 [cytosol] (Rattus norvegicus)
Cdc20:phospho-APC/C:Cyclin B:Cdc2 complex [cytosol] (Rattus norvegicus)
CDC20:p-APC/C [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Cdc26 [cytosol] (Rattus norvegicus)
Degradation of multiubiquitinated Cyclin B (Rattus norvegicus)
CDC20:p-APC/C [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Cdc26 [cytosol] (Rattus norvegicus)
multiubiquitinated Cyclin B:Cdc2:Cdc20:phospho-APC/C complex [cytosol] (Rattus norvegicus)
Cdc20:phospho-APC/C:Cyclin B:Cdc2 complex [cytosol] (Rattus norvegicus)
CDC20:p-APC/C [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Cdc26 [cytosol] (Rattus norvegicus)
Ubiquitination of Cyclin B by phospho-APC/C:Cdc20 complex (Rattus norvegicus)
Cdc20:phospho-APC/C:Cyclin B:Cdc2 complex [cytosol] (Rattus norvegicus)
CDC20:p-APC/C [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Cdc26 [cytosol] (Rattus norvegicus)
multiubiquitinated Cyclin B:Cdc2:Cdc20:phospho-APC/C complex [cytosol] (Rattus norvegicus)
Cdc20:phospho-APC/C:Cyclin B:Cdc2 complex [cytosol] (Rattus norvegicus)
CDC20:p-APC/C [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Cdc26 [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Cdc26 [cytosol] (Rattus norvegicus)
APC/C:Cdc20 mediated degradation of Securin (Rattus norvegicus)
Association of Securin with Cdc20:APC/C complex (Rattus norvegicus)
CDC20:p-APC/C [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Cdc26 [cytosol] (Rattus norvegicus)
CDC20:p-APC/C:PTTG1 [cytosol] (Rattus norvegicus)
CDC20:p-APC/C [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Cdc26 [cytosol] (Rattus norvegicus)
Degradation of multiubiquitinated Securin (Rattus norvegicus)
CDC20:p-APC/C [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Cdc26 [cytosol] (Rattus norvegicus)
CDC20:pAPC/C:K11polyUb-PTTG1 [cytosol] (Rattus norvegicus)
CDC20:p-APC/C [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Cdc26 [cytosol] (Rattus norvegicus)
Ubiquitination of Securin by phospho-APC/C:Cdc20 complex (Rattus norvegicus)
CDC20:p-APC/C:PTTG1 [cytosol] (Rattus norvegicus)
CDC20:p-APC/C [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Cdc26 [cytosol] (Rattus norvegicus)
CDC20:pAPC/C:K11polyUb-PTTG1 [cytosol] (Rattus norvegicus)
CDC20:p-APC/C [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Cdc26 [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Cdc26 [cytosol] (Rattus norvegicus)
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint (Rattus norvegicus)
APC-Cdc20 mediated degradation of Nek2A (Rattus norvegicus)
Association of Nek2A with MCC:APC/C (Rattus norvegicus)
MCC:APC/C complex [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Cdc26 [cytosol] (Rattus norvegicus)
Nek2A:MCC:APC/C complex [cytosol] (Rattus norvegicus)
MCC:APC/C complex [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Cdc26 [cytosol] (Rattus norvegicus)
Degradation of multiubiquitinated Nek2A (Rattus norvegicus)
MCC:APC/C complex [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Cdc26 [cytosol] (Rattus norvegicus)
Multiubiquitinated Nek2A [cytosol] (Rattus norvegicus)
Nek2A:MCC:APC/C complex [cytosol] (Rattus norvegicus)
MCC:APC/C complex [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Cdc26 [cytosol] (Rattus norvegicus)
Multiubiquitination of Nek2A (Rattus norvegicus)
Multiubiquitinated Nek2A [cytosol] (Rattus norvegicus)
Nek2A:MCC:APC/C complex [cytosol] (Rattus norvegicus)
MCC:APC/C complex [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Cdc26 [cytosol] (Rattus norvegicus)
Nek2A:MCC:APC/C complex [cytosol] (Rattus norvegicus)
MCC:APC/C complex [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Cdc26 [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Cdc26 [cytosol] (Rattus norvegicus)
Cdc20:Phospho-APC/C mediated degradation of Cyclin A (Rattus norvegicus)
Association of Cyclin A with the APC/C (Rattus norvegicus)
Cdc2:Cyclin A:MCC:APC/C complex [cytosol] (Rattus norvegicus)
MCC:APC/C complex [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Cdc26 [cytosol] (Rattus norvegicus)
MCC:APC/C complex [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Cdc26 [cytosol] (Rattus norvegicus)
Degradation multiubiquitinated Cyclin A (Rattus norvegicus)
MCC:APC/C complex [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Cdc26 [cytosol] (Rattus norvegicus)
multiubiquitinated Cyclin A associated with MCC:APC/C complex [cytosol] (Rattus norvegicus)
Cdc2:Cyclin A:MCC:APC/C complex [cytosol] (Rattus norvegicus)
MCC:APC/C complex [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Cdc26 [cytosol] (Rattus norvegicus)
Ubiquitination of Cyclin A by APC/C:Cdc20 complex (Rattus norvegicus)
Cdc2:Cyclin A:MCC:APC/C complex [cytosol] (Rattus norvegicus)
MCC:APC/C complex [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Cdc26 [cytosol] (Rattus norvegicus)
MCC:APC/C complex [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Cdc26 [cytosol] (Rattus norvegicus)
multiubiquitinated Cyclin A associated with MCC:APC/C complex [cytosol] (Rattus norvegicus)
Cdc2:Cyclin A:MCC:APC/C complex [cytosol] (Rattus norvegicus)
MCC:APC/C complex [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Cdc26 [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Cdc26 [cytosol] (Rattus norvegicus)
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase (Rattus norvegicus)
Association of Cdh1 with the APC/C (Rattus norvegicus)
phospho-APC/C:Cdh1 complex [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Cdc26 [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Cdc26 [cytosol] (Rattus norvegicus)
Dissociation of Cdc20 from APC/C complex (Rattus norvegicus)
CDC20:p-APC/C [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Cdc26 [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Cdc26 [cytosol] (Rattus norvegicus)
Regulation of APC/C activators between G1/S and early anaphase (Rattus norvegicus)
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components (Rattus norvegicus)
Inactivation of APC/C via direct inhibition of the APC/C complex (Rattus norvegicus)
Binding of the MCC complex to the APC/C complex (Rattus norvegicus)
MCC:APC/C complex [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Cdc26 [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Cdc26 [cytosol] (Rattus norvegicus)
S Phase (Rattus norvegicus)
Synthesis of DNA (Rattus norvegicus)
Switching of origins to a post-replicative state (Rattus norvegicus)
CDK-mediated phosphorylation and removal of Cdc6 (Rattus norvegicus)
Cytoplasmic phosphorylated Cdc6 is ubiquitinated by the anaphase-promoting complex (Rattus norvegicus)
phospho-APC/C:Cdh1 complex [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Cdc26 [cytosol] (Rattus norvegicus)
DNA Replication (Rattus norvegicus)
Synthesis of DNA (Rattus norvegicus)
Switching of origins to a post-replicative state (Rattus norvegicus)
CDK-mediated phosphorylation and removal of Cdc6 (Rattus norvegicus)
Cytoplasmic phosphorylated Cdc6 is ubiquitinated by the anaphase-promoting complex (Rattus norvegicus)
phospho-APC/C:Cdh1 complex [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Cdc26 [cytosol] (Rattus norvegicus)
Immune System (Rattus norvegicus)
Adaptive Immune System (Rattus norvegicus)
Class I MHC mediated antigen processing & presentation (Rattus norvegicus)
Antigen processing: Ubiquitination & Proteasome degradation (Rattus norvegicus)
Interaction of E3 with substrate and E2-Ub complex (Rattus norvegicus)
Ag-substrate:E3:E2:Ub [cytosol] (Rattus norvegicus)
E3 ligases in proteasomal degradation [cytosol] (Rattus norvegicus)
APC/C E3 ligase complex [cytosol] (Rattus norvegicus)
Cdc26 [cytosol] (Rattus norvegicus)
E3 ligases in proteasomal degradation [cytosol] (Rattus norvegicus)
APC/C E3 ligase complex [cytosol] (Rattus norvegicus)
Cdc26 [cytosol] (Rattus norvegicus)
Polyubiquitination of substrate (Rattus norvegicus)
E3 ligases in proteasomal degradation [cytosol] (Rattus norvegicus)
APC/C E3 ligase complex [cytosol] (Rattus norvegicus)
Cdc26 [cytosol] (Rattus norvegicus)
E3:K48-polyubiquitinated substrate [cytosol] (Rattus norvegicus)
E3 ligases in proteasomal degradation [cytosol] (Rattus norvegicus)
APC/C E3 ligase complex [cytosol] (Rattus norvegicus)
Cdc26 [cytosol] (Rattus norvegicus)
E3:Ub:substrate [cytosol] (Rattus norvegicus)
E3 ligases in proteasomal degradation [cytosol] (Rattus norvegicus)
APC/C E3 ligase complex [cytosol] (Rattus norvegicus)
Cdc26 [cytosol] (Rattus norvegicus)
Release of E3 from polyubiquitinated substrate (Rattus norvegicus)
E3 ligases in proteasomal degradation [cytosol] (Rattus norvegicus)
APC/C E3 ligase complex [cytosol] (Rattus norvegicus)
Cdc26 [cytosol] (Rattus norvegicus)
E3:K48-polyubiquitinated substrate [cytosol] (Rattus norvegicus)
E3 ligases in proteasomal degradation [cytosol] (Rattus norvegicus)
APC/C E3 ligase complex [cytosol] (Rattus norvegicus)
Cdc26 [cytosol] (Rattus norvegicus)
Transfer of Ub from E2 to substrate and release of E2 (Rattus norvegicus)
Ag-substrate:E3:E2:Ub [cytosol] (Rattus norvegicus)
E3 ligases in proteasomal degradation [cytosol] (Rattus norvegicus)
APC/C E3 ligase complex [cytosol] (Rattus norvegicus)
Cdc26 [cytosol] (Rattus norvegicus)
E3 ligases in proteasomal degradation [cytosol] (Rattus norvegicus)
APC/C E3 ligase complex [cytosol] (Rattus norvegicus)
Cdc26 [cytosol] (Rattus norvegicus)
E3:Ub:substrate [cytosol] (Rattus norvegicus)
E3 ligases in proteasomal degradation [cytosol] (Rattus norvegicus)
APC/C E3 ligase complex [cytosol] (Rattus norvegicus)
Cdc26 [cytosol] (Rattus norvegicus)
External Reference Information
External Reference
UniProt:Q6YDN7
Gene Names
Cdc26
Reference Genes
BioGPS Gene:366381 Cdc26
ENSEMBL:ENSRNOG00000029785
ENSEMBL:ENSRNOG00055019546
ENSEMBL:ENSRNOG00060009971
ENSEMBL:ENSRNOG00065015890
KEGG Gene (Rattus norvegicus):366381 Cdc26
Monarch:366381 Cdc26
NCBI Gene:366381 Cdc26
Reference Transcript
RefSeq:XM_006238242.2 Cdc26
RefSeq:NM_001267054.1 Cdc26
RefSeq:XM_008763796.2 Cdc26
RefSeq:NM_001267055.1 Cdc26
RefSeq:NM_001013240.2 Cdc26
Participates
as a component of
APC/C E3 ligase complex [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Other forms of this molecule
Cdc26 [nucleoplasm]
Inferred From
CDC26 [cytosol]
(Homo sapiens)
Cross References
RefSeq
XP_008762018.1
,
NP_001013258.1
,
NP_001253984.1
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XP_006238304.1
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NP_001253983.1
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