Reactome | Sh3gl2 [plasma membrane]

Sh3gl2 [plasma membrane]

Stable Identifier

R-RNO-177495

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

plasma membrane

Synonyms

SH3GL2, O35179

Locations in the PathwayBrowser

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Signal Transduction (Rattus norvegicus)

- Signaling by Receptor Tyrosine Kinases (Rattus norvegicus)
  - Signaling by NTRKs (Rattus norvegicus)
    - Signaling by NTRK1 (TRKA) (Rattus norvegicus)
      - Retrograde neurotrophin signalling (Rattus norvegicus)
        
        Axonal transport of NGF:Trk complexes (Rattus norvegicus)
        
        Activated TrkA receptor complex:Clathrin-coated vesicle:Endophilin [plasma membrane] (Rattus norvegicus)
        
        Sh3gl2 [plasma membrane] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:O35179 Sh3gl2

Gene Names

Sh3gl2, Sh3d2a, Sh3p4

Chain

chain:1-352

Reference Genes

BioGPS Gene:116743 Sh3gl2

KEGG Gene (Rattus norvegicus):116743 Sh3gl2

Monarch:116743 Sh3gl2

NCBI Gene:116743 Sh3gl2

UCSC:O35179 Sh3gl2

Reference Transcript

RefSeq:NM_053935.1 Sh3gl2

Participates

as an input of

as a component of

as an output of

Reinsertion of L1 into the plasma membrane (Rattus norvegicus)

Other forms of this molecule

Sh3gl2 [Golgi membrane]

Sh3gl2 [clathrin-coated endocytic vesicle membrane]

Endophilin [plasma membrane]

Sh3gl2 [cytosol]

Inferred From

SH3GL2 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_446387.1

PRO

O35179

RGD

620276

PDB

2C08, 2KNB, 3IQL

Interactors (4)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P21575 Dnm1	4	DNM1 [cytosol] (R-RNO-2213182) Dynamin 1 [plasma membrane] (R-RNO-941853) DNM1 [lysosomal membrane] (R-RNO-196150) DNM1 [plasma membrane] (R-RNO-177488)	0.785	7
UniProt:O43295 SRGAP3	1	SRGAP3 [cytosol] (R-HSA-428463)	0.544	3
UniProt:Q62910	1	Synj1 [cytosol] (R-RNO-1604634)	0.499	2
UniProt:O60260 PARK2	3	polyUb-PARK2 [cytosol] (R-HSA-5689094) p-S9-PRKN [cytosol] (R-HSA-9793481) PRKN [cytosol] (R-HSA-201579)	0.462	2

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