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About
What is Reactome ?
News
Team
Scientific Advisory Board
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Editorial Calendar
Release Calendar
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Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
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Table of Contents
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Gab1 [cytosol]
Stable Identifier
R-RNO-179795
Type
Protein [EntityWithAccessionedSequence]
Species
Rattus norvegicus
Compartment
cytosol
Synonyms
GAB1, D3ZAL7
Locations in the PathwayBrowser
Expand all
Developmental Biology (Rattus norvegicus)
Nervous system development (Rattus norvegicus)
Axon guidance (Rattus norvegicus)
RET signaling (Rattus norvegicus)
GAB in p-5Y-RET:GDNF:GFRA complexes is phosphorylated (Rattus norvegicus)
2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1:GAB1,GAB2 [plasma membrane] (Rattus norvegicus)
GAB1,GAB2 [cytosol] (Rattus norvegicus)
Gab1 [cytosol] (Rattus norvegicus)
p-5Y-RET-GRB2-containing complexes bind GAB1,GAB2 (Rattus norvegicus)
2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1:GAB1,GAB2 [plasma membrane] (Rattus norvegicus)
GAB1,GAB2 [cytosol] (Rattus norvegicus)
Gab1 [cytosol] (Rattus norvegicus)
GAB1,GAB2 [cytosol] (Rattus norvegicus)
Gab1 [cytosol] (Rattus norvegicus)
Signal Transduction (Rattus norvegicus)
Intracellular signaling by second messengers (Rattus norvegicus)
PIP3 activates AKT signaling (Rattus norvegicus)
Negative regulation of the PI3K/AKT network (Rattus norvegicus)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Rattus norvegicus)
PI3K phosphorylates PIP2 to PIP3 (Rattus norvegicus)
Activator:PI3K [plasma membrane] (Rattus norvegicus)
Activated FGFR1:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] (Rattus norvegicus)
Activated FGFR1:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Rattus norvegicus)
GRB2:GAB1:PIK3R1 [cytosol] (Rattus norvegicus)
GRB2:GAB1 [cytosol] (Rattus norvegicus)
Gab1 [cytosol] (Rattus norvegicus)
Activated FGFR1:p-FRS2:p-PTPN11:GRB2:GAB1:PI3K [plasma membrane] (Rattus norvegicus)
Activated FGFR:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Rattus norvegicus)
GRB2:GAB1:PIK3R1 [cytosol] (Rattus norvegicus)
GRB2:GAB1 [cytosol] (Rattus norvegicus)
Gab1 [cytosol] (Rattus norvegicus)
Activated FGFR2:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] (Rattus norvegicus)
Activated FGFR2:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Rattus norvegicus)
GRB2:GAB1:PIK3R1 [cytosol] (Rattus norvegicus)
GRB2:GAB1 [cytosol] (Rattus norvegicus)
Gab1 [cytosol] (Rattus norvegicus)
Activated FGFR2:p-FRS2:p-PTPN11:GRB2:GAB1:PI3K [plasma membrane] (Rattus norvegicus)
Activated FGFR2:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Rattus norvegicus)
GRB2:GAB1:PIK3R1 [cytosol] (Rattus norvegicus)
GRB2:GAB1 [cytosol] (Rattus norvegicus)
Gab1 [cytosol] (Rattus norvegicus)
Activated FGFR3:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] (Rattus norvegicus)
Activated FGFR3:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Rattus norvegicus)
GRB2:GAB1:PIK3R1 [cytosol] (Rattus norvegicus)
GRB2:GAB1 [cytosol] (Rattus norvegicus)
Gab1 [cytosol] (Rattus norvegicus)
Activated FGFR3:p-FRS2:p-PTPN11:GRB2:GAB1:PI3K [plasma membrane] (Rattus norvegicus)
Activated FGFR3:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Rattus norvegicus)
GRB2:GAB1:PIK3R1 [cytosol] (Rattus norvegicus)
GRB2:GAB1 [cytosol] (Rattus norvegicus)
Gab1 [cytosol] (Rattus norvegicus)
Activated FGFR4:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] (Rattus norvegicus)
Activated FGFR4:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Rattus norvegicus)
GRB2:GAB1:PIK3R1 [cytosol] (Rattus norvegicus)
GRB2:GAB1 [cytosol] (Rattus norvegicus)
Gab1 [cytosol] (Rattus norvegicus)
BDNF,NTF4:p-5Y-NTRK2:GRB2:GAB1:PIK3CA:PIK3R1 [plasma membrane] (Rattus norvegicus)
GRB2:GAB1 [cytosol] (Rattus norvegicus)
Gab1 [cytosol] (Rattus norvegicus)
EGF:p-EGFR:p-ERBB2:GRB2:GAB1:PI3K [plasma membrane] (Rattus norvegicus)
EGF:p-EGFR:p-ERBB2:GRB2:GAB1:PIK3R1 [plasma membrane] (Rattus norvegicus)
EGF:p-EGFR:p-ERBB2:GRB2:GAB1 [plasma membrane] (Rattus norvegicus)
GRB2:GAB1 [cytosol] (Rattus norvegicus)
Gab1 [cytosol] (Rattus norvegicus)
PI3K phosphorylates PIP2 to PIP3 (Rattus norvegicus)
Activator:PI3K [plasma membrane] (Rattus norvegicus)
Activated FGFR1:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] (Rattus norvegicus)
Activated FGFR1:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Rattus norvegicus)
GRB2:GAB1:PIK3R1 [cytosol] (Rattus norvegicus)
GRB2:GAB1 [cytosol] (Rattus norvegicus)
Gab1 [cytosol] (Rattus norvegicus)
Activated FGFR1:p-FRS2:p-PTPN11:GRB2:GAB1:PI3K [plasma membrane] (Rattus norvegicus)
Activated FGFR:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Rattus norvegicus)
GRB2:GAB1:PIK3R1 [cytosol] (Rattus norvegicus)
GRB2:GAB1 [cytosol] (Rattus norvegicus)
Gab1 [cytosol] (Rattus norvegicus)
Activated FGFR2:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] (Rattus norvegicus)
Activated FGFR2:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Rattus norvegicus)
GRB2:GAB1:PIK3R1 [cytosol] (Rattus norvegicus)
GRB2:GAB1 [cytosol] (Rattus norvegicus)
Gab1 [cytosol] (Rattus norvegicus)
Activated FGFR2:p-FRS2:p-PTPN11:GRB2:GAB1:PI3K [plasma membrane] (Rattus norvegicus)
Activated FGFR2:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Rattus norvegicus)
GRB2:GAB1:PIK3R1 [cytosol] (Rattus norvegicus)
GRB2:GAB1 [cytosol] (Rattus norvegicus)
Gab1 [cytosol] (Rattus norvegicus)
Activated FGFR3:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] (Rattus norvegicus)
Activated FGFR3:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Rattus norvegicus)
GRB2:GAB1:PIK3R1 [cytosol] (Rattus norvegicus)
GRB2:GAB1 [cytosol] (Rattus norvegicus)
Gab1 [cytosol] (Rattus norvegicus)
Activated FGFR3:p-FRS2:p-PTPN11:GRB2:GAB1:PI3K [plasma membrane] (Rattus norvegicus)
Activated FGFR3:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Rattus norvegicus)
GRB2:GAB1:PIK3R1 [cytosol] (Rattus norvegicus)
GRB2:GAB1 [cytosol] (Rattus norvegicus)
Gab1 [cytosol] (Rattus norvegicus)
Activated FGFR4:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] (Rattus norvegicus)
Activated FGFR4:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Rattus norvegicus)
GRB2:GAB1:PIK3R1 [cytosol] (Rattus norvegicus)
GRB2:GAB1 [cytosol] (Rattus norvegicus)
Gab1 [cytosol] (Rattus norvegicus)
BDNF,NTF4:p-5Y-NTRK2:GRB2:GAB1:PIK3CA:PIK3R1 [plasma membrane] (Rattus norvegicus)
GRB2:GAB1 [cytosol] (Rattus norvegicus)
Gab1 [cytosol] (Rattus norvegicus)
EGF:p-EGFR:p-ERBB2:GRB2:GAB1:PI3K [plasma membrane] (Rattus norvegicus)
EGF:p-EGFR:p-ERBB2:GRB2:GAB1:PIK3R1 [plasma membrane] (Rattus norvegicus)
EGF:p-EGFR:p-ERBB2:GRB2:GAB1 [plasma membrane] (Rattus norvegicus)
GRB2:GAB1 [cytosol] (Rattus norvegicus)
Gab1 [cytosol] (Rattus norvegicus)
Signaling by Erythropoietin (Rattus norvegicus)
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) (Rattus norvegicus)
EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2 binds GAB1 (Rattus norvegicus)
EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:IRS2:GAB1 [plasma membrane] (Rattus norvegicus)
Gab1 [cytosol] (Rattus norvegicus)
Gab1 [cytosol] (Rattus norvegicus)
JAK2 phosphorylates GAB1 in EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2:GAB1 (Rattus norvegicus)
EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:IRS2:GAB1 [plasma membrane] (Rattus norvegicus)
Gab1 [cytosol] (Rattus norvegicus)
Signaling by Receptor Tyrosine Kinases (Rattus norvegicus)
Signaling by EGFR (Rattus norvegicus)
GAB1 signalosome (Rattus norvegicus)
Binding of GRB2 to GAB1 (Rattus norvegicus)
GRB2:GAB1 [cytosol] (Rattus norvegicus)
Gab1 [cytosol] (Rattus norvegicus)
Gab1 [cytosol] (Rattus norvegicus)
GAB1 binds phosphatidylinositol-3,4,5-trisphosphate (Rattus norvegicus)
GRB2:GAB1 [cytosol] (Rattus norvegicus)
Gab1 [cytosol] (Rattus norvegicus)
GRB2:GAB1:PIP3 [plasma membrane] (Rattus norvegicus)
GRB2:GAB1 [cytosol] (Rattus norvegicus)
Gab1 [cytosol] (Rattus norvegicus)
GAB1 phosphorylation by EGFR kinase (Rattus norvegicus)
EGF-like ligands:p-6Y-EGFR:GRB2:GAB1 [plasma membrane] (Rattus norvegicus)
GRB2:GAB1,GRB2:GAB1:PIP3 [cytosol] (Rattus norvegicus)
GRB2:GAB1 [cytosol] (Rattus norvegicus)
Gab1 [cytosol] (Rattus norvegicus)
GRB2:GAB1:PIP3 [plasma membrane] (Rattus norvegicus)
GRB2:GAB1 [cytosol] (Rattus norvegicus)
Gab1 [cytosol] (Rattus norvegicus)
GRB2:GAB1 binds to phosphorylated EGFR (Rattus norvegicus)
EGF-like ligands:p-6Y-EGFR:GRB2:GAB1 [plasma membrane] (Rattus norvegicus)
GRB2:GAB1,GRB2:GAB1:PIP3 [cytosol] (Rattus norvegicus)
GRB2:GAB1 [cytosol] (Rattus norvegicus)
Gab1 [cytosol] (Rattus norvegicus)
GRB2:GAB1:PIP3 [plasma membrane] (Rattus norvegicus)
GRB2:GAB1 [cytosol] (Rattus norvegicus)
Gab1 [cytosol] (Rattus norvegicus)
GRB2:GAB1,GRB2:GAB1:PIP3 [cytosol] (Rattus norvegicus)
GRB2:GAB1 [cytosol] (Rattus norvegicus)
Gab1 [cytosol] (Rattus norvegicus)
GRB2:GAB1:PIP3 [plasma membrane] (Rattus norvegicus)
GRB2:GAB1 [cytosol] (Rattus norvegicus)
Gab1 [cytosol] (Rattus norvegicus)
Signaling by ERBB2 (Rattus norvegicus)
PI3K events in ERBB2 signaling (Rattus norvegicus)
Binding of GRB2:GAB1 to p-ERBB2:p-EGFR (Rattus norvegicus)
EGF:p-EGFR:p-ERBB2:GRB2:GAB1 [plasma membrane] (Rattus norvegicus)
GRB2:GAB1 [cytosol] (Rattus norvegicus)
Gab1 [cytosol] (Rattus norvegicus)
GRB2:GAB1 [cytosol] (Rattus norvegicus)
Gab1 [cytosol] (Rattus norvegicus)
Binding of PI3K to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR (Rattus norvegicus)
EGF:p-EGFR:p-ERBB2:GRB2:GAB1 [plasma membrane] (Rattus norvegicus)
GRB2:GAB1 [cytosol] (Rattus norvegicus)
Gab1 [cytosol] (Rattus norvegicus)
EGF:p-EGFR:p-ERBB2:GRB2:GAB1:PI3K [plasma membrane] (Rattus norvegicus)
EGF:p-EGFR:p-ERBB2:GRB2:GAB1:PIK3R1 [plasma membrane] (Rattus norvegicus)
EGF:p-EGFR:p-ERBB2:GRB2:GAB1 [plasma membrane] (Rattus norvegicus)
GRB2:GAB1 [cytosol] (Rattus norvegicus)
Gab1 [cytosol] (Rattus norvegicus)
PIP2 to PIP3 conversion by PI3K bound to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR (Rattus norvegicus)
EGF:p-EGFR:p-ERBB2:GRB2:GAB1:PI3K [plasma membrane] (Rattus norvegicus)
EGF:p-EGFR:p-ERBB2:GRB2:GAB1:PIK3R1 [plasma membrane] (Rattus norvegicus)
EGF:p-EGFR:p-ERBB2:GRB2:GAB1 [plasma membrane] (Rattus norvegicus)
GRB2:GAB1 [cytosol] (Rattus norvegicus)
Gab1 [cytosol] (Rattus norvegicus)
Signaling by FGFR (Rattus norvegicus)
Signaling by FGFR1 (Rattus norvegicus)
Downstream signaling of activated FGFR1 (Rattus norvegicus)
PI-3K cascade:FGFR1 (Rattus norvegicus)
Activated FGFR1:p-FRS2 binds GRB2:GAB1:PIK3R1 (Rattus norvegicus)
Activated FGFR1:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Rattus norvegicus)
GRB2:GAB1:PIK3R1 [cytosol] (Rattus norvegicus)
GRB2:GAB1 [cytosol] (Rattus norvegicus)
Gab1 [cytosol] (Rattus norvegicus)
GRB2:GAB1:PIK3R1 [cytosol] (Rattus norvegicus)
GRB2:GAB1 [cytosol] (Rattus norvegicus)
Gab1 [cytosol] (Rattus norvegicus)
Activated FGFR1:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA (Rattus norvegicus)
Activated FGFR1:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] (Rattus norvegicus)
Activated FGFR1:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Rattus norvegicus)
GRB2:GAB1:PIK3R1 [cytosol] (Rattus norvegicus)
GRB2:GAB1 [cytosol] (Rattus norvegicus)
Gab1 [cytosol] (Rattus norvegicus)
Activated FGFR1:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Rattus norvegicus)
GRB2:GAB1:PIK3R1 [cytosol] (Rattus norvegicus)
GRB2:GAB1 [cytosol] (Rattus norvegicus)
Gab1 [cytosol] (Rattus norvegicus)
Activated FGFR1:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 (Rattus norvegicus)
Activated FGFR:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Rattus norvegicus)
GRB2:GAB1:PIK3R1 [cytosol] (Rattus norvegicus)
GRB2:GAB1 [cytosol] (Rattus norvegicus)
Gab1 [cytosol] (Rattus norvegicus)
GRB2:GAB1:PIK3R1 [cytosol] (Rattus norvegicus)
GRB2:GAB1 [cytosol] (Rattus norvegicus)
Gab1 [cytosol] (Rattus norvegicus)
Activated FGFR1:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1 binds PIK3CA (Rattus norvegicus)
Activated FGFR1:p-FRS2:p-PTPN11:GRB2:GAB1:PI3K [plasma membrane] (Rattus norvegicus)
Activated FGFR:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Rattus norvegicus)
GRB2:GAB1:PIK3R1 [cytosol] (Rattus norvegicus)
GRB2:GAB1 [cytosol] (Rattus norvegicus)
Gab1 [cytosol] (Rattus norvegicus)
Activated FGFR:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Rattus norvegicus)
GRB2:GAB1:PIK3R1 [cytosol] (Rattus norvegicus)
GRB2:GAB1 [cytosol] (Rattus norvegicus)
Gab1 [cytosol] (Rattus norvegicus)
Binding of PIK3 regulatory alpha subunit to GRB2:GAB1 (Rattus norvegicus)
GRB2:GAB1 [cytosol] (Rattus norvegicus)
Gab1 [cytosol] (Rattus norvegicus)
GRB2:GAB1:PIK3R1 [cytosol] (Rattus norvegicus)
GRB2:GAB1 [cytosol] (Rattus norvegicus)
Gab1 [cytosol] (Rattus norvegicus)
FGFR1- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 (Rattus norvegicus)
Activated FGFR1:p-FRS2:p-PTPN11:GRB2:GAB1:PI3K [plasma membrane] (Rattus norvegicus)
Activated FGFR:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Rattus norvegicus)
GRB2:GAB1:PIK3R1 [cytosol] (Rattus norvegicus)
GRB2:GAB1 [cytosol] (Rattus norvegicus)
Gab1 [cytosol] (Rattus norvegicus)
FGFR1-associated PI3K phosphorylates PIP2 to PIP3 (Rattus norvegicus)
Activated FGFR1:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] (Rattus norvegicus)
Activated FGFR1:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Rattus norvegicus)
GRB2:GAB1:PIK3R1 [cytosol] (Rattus norvegicus)
GRB2:GAB1 [cytosol] (Rattus norvegicus)
Gab1 [cytosol] (Rattus norvegicus)
Signaling by FGFR2 (Rattus norvegicus)
Downstream signaling of activated FGFR2 (Rattus norvegicus)
PI-3K cascade:FGFR2 (Rattus norvegicus)
Activated FGFR2:p-FRS2 binds GRB2:GAB1:PIK3R1 (Rattus norvegicus)
Activated FGFR2:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Rattus norvegicus)
GRB2:GAB1:PIK3R1 [cytosol] (Rattus norvegicus)
GRB2:GAB1 [cytosol] (Rattus norvegicus)
Gab1 [cytosol] (Rattus norvegicus)
GRB2:GAB1:PIK3R1 [cytosol] (Rattus norvegicus)
GRB2:GAB1 [cytosol] (Rattus norvegicus)
Gab1 [cytosol] (Rattus norvegicus)
Activated FGFR2:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA (Rattus norvegicus)
Activated FGFR2:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] (Rattus norvegicus)
Activated FGFR2:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Rattus norvegicus)
GRB2:GAB1:PIK3R1 [cytosol] (Rattus norvegicus)
GRB2:GAB1 [cytosol] (Rattus norvegicus)
Gab1 [cytosol] (Rattus norvegicus)
Activated FGFR2:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Rattus norvegicus)
GRB2:GAB1:PIK3R1 [cytosol] (Rattus norvegicus)
GRB2:GAB1 [cytosol] (Rattus norvegicus)
Gab1 [cytosol] (Rattus norvegicus)
Activated FGFR2:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 (Rattus norvegicus)
Activated FGFR2:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Rattus norvegicus)
GRB2:GAB1:PIK3R1 [cytosol] (Rattus norvegicus)
GRB2:GAB1 [cytosol] (Rattus norvegicus)
Gab1 [cytosol] (Rattus norvegicus)
GRB2:GAB1:PIK3R1 [cytosol] (Rattus norvegicus)
GRB2:GAB1 [cytosol] (Rattus norvegicus)
Gab1 [cytosol] (Rattus norvegicus)
Activated FGFR2:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1 binds PIK3CA (Rattus norvegicus)
Activated FGFR2:p-FRS2:p-PTPN11:GRB2:GAB1:PI3K [plasma membrane] (Rattus norvegicus)
Activated FGFR2:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Rattus norvegicus)
GRB2:GAB1:PIK3R1 [cytosol] (Rattus norvegicus)
GRB2:GAB1 [cytosol] (Rattus norvegicus)
Gab1 [cytosol] (Rattus norvegicus)
Activated FGFR2:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Rattus norvegicus)
GRB2:GAB1:PIK3R1 [cytosol] (Rattus norvegicus)
GRB2:GAB1 [cytosol] (Rattus norvegicus)
Gab1 [cytosol] (Rattus norvegicus)
Binding of PIK3 regulatory alpha subunit to GRB2:GAB1 (Rattus norvegicus)
GRB2:GAB1 [cytosol] (Rattus norvegicus)
Gab1 [cytosol] (Rattus norvegicus)
GRB2:GAB1:PIK3R1 [cytosol] (Rattus norvegicus)
GRB2:GAB1 [cytosol] (Rattus norvegicus)
Gab1 [cytosol] (Rattus norvegicus)
FGFR2- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 (Rattus norvegicus)
Activated FGFR2:p-FRS2:p-PTPN11:GRB2:GAB1:PI3K [plasma membrane] (Rattus norvegicus)
Activated FGFR2:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Rattus norvegicus)
GRB2:GAB1:PIK3R1 [cytosol] (Rattus norvegicus)
GRB2:GAB1 [cytosol] (Rattus norvegicus)
Gab1 [cytosol] (Rattus norvegicus)
FGFR2-associated PI3K phosphorylates PIP2 to PIP3 (Rattus norvegicus)
Activated FGFR2:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] (Rattus norvegicus)
Activated FGFR2:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Rattus norvegicus)
GRB2:GAB1:PIK3R1 [cytosol] (Rattus norvegicus)
GRB2:GAB1 [cytosol] (Rattus norvegicus)
Gab1 [cytosol] (Rattus norvegicus)
Signaling by FGFR3 (Rattus norvegicus)
Downstream signaling of activated FGFR3 (Rattus norvegicus)
PI-3K cascade:FGFR3 (Rattus norvegicus)
Activated FGFR3:p-FRS2 binds GRB2:GAB1:PIK3R1 (Rattus norvegicus)
Activated FGFR3:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Rattus norvegicus)
GRB2:GAB1:PIK3R1 [cytosol] (Rattus norvegicus)
GRB2:GAB1 [cytosol] (Rattus norvegicus)
Gab1 [cytosol] (Rattus norvegicus)
GRB2:GAB1:PIK3R1 [cytosol] (Rattus norvegicus)
GRB2:GAB1 [cytosol] (Rattus norvegicus)
Gab1 [cytosol] (Rattus norvegicus)
Activated FGFR3:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA (Rattus norvegicus)
Activated FGFR3:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] (Rattus norvegicus)
Activated FGFR3:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Rattus norvegicus)
GRB2:GAB1:PIK3R1 [cytosol] (Rattus norvegicus)
GRB2:GAB1 [cytosol] (Rattus norvegicus)
Gab1 [cytosol] (Rattus norvegicus)
Activated FGFR3:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Rattus norvegicus)
GRB2:GAB1:PIK3R1 [cytosol] (Rattus norvegicus)
GRB2:GAB1 [cytosol] (Rattus norvegicus)
Gab1 [cytosol] (Rattus norvegicus)
Activated FGFR3:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 (Rattus norvegicus)
Activated FGFR3:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Rattus norvegicus)
GRB2:GAB1:PIK3R1 [cytosol] (Rattus norvegicus)
GRB2:GAB1 [cytosol] (Rattus norvegicus)
Gab1 [cytosol] (Rattus norvegicus)
GRB2:GAB1:PIK3R1 [cytosol] (Rattus norvegicus)
GRB2:GAB1 [cytosol] (Rattus norvegicus)
Gab1 [cytosol] (Rattus norvegicus)
Activated FGFR3:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1 binds PIK3CA (Rattus norvegicus)
Activated FGFR3:p-FRS2:p-PTPN11:GRB2:GAB1:PI3K [plasma membrane] (Rattus norvegicus)
Activated FGFR3:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Rattus norvegicus)
GRB2:GAB1:PIK3R1 [cytosol] (Rattus norvegicus)
GRB2:GAB1 [cytosol] (Rattus norvegicus)
Gab1 [cytosol] (Rattus norvegicus)
Activated FGFR3:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Rattus norvegicus)
GRB2:GAB1:PIK3R1 [cytosol] (Rattus norvegicus)
GRB2:GAB1 [cytosol] (Rattus norvegicus)
Gab1 [cytosol] (Rattus norvegicus)
Binding of PIK3 regulatory alpha subunit to GRB2:GAB1 (Rattus norvegicus)
GRB2:GAB1 [cytosol] (Rattus norvegicus)
Gab1 [cytosol] (Rattus norvegicus)
GRB2:GAB1:PIK3R1 [cytosol] (Rattus norvegicus)
GRB2:GAB1 [cytosol] (Rattus norvegicus)
Gab1 [cytosol] (Rattus norvegicus)
FGFR3- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 (Rattus norvegicus)
Activated FGFR3:p-FRS2:p-PTPN11:GRB2:GAB1:PI3K [plasma membrane] (Rattus norvegicus)
Activated FGFR3:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Rattus norvegicus)
GRB2:GAB1:PIK3R1 [cytosol] (Rattus norvegicus)
GRB2:GAB1 [cytosol] (Rattus norvegicus)
Gab1 [cytosol] (Rattus norvegicus)
FGFR3-associated PI3K phosphorylates PIP2 to PIP3 (Rattus norvegicus)
Activated FGFR3:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] (Rattus norvegicus)
Activated FGFR3:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Rattus norvegicus)
GRB2:GAB1:PIK3R1 [cytosol] (Rattus norvegicus)
GRB2:GAB1 [cytosol] (Rattus norvegicus)
Gab1 [cytosol] (Rattus norvegicus)
Signaling by FGFR4 (Rattus norvegicus)
Downstream signaling of activated FGFR4 (Rattus norvegicus)
PI-3K cascade:FGFR4 (Rattus norvegicus)
Activated FGFR4:p-FRS2 binds GRB2:GAB1:PIK3R1 (Rattus norvegicus)
Activated FGFR4:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Rattus norvegicus)
GRB2:GAB1:PIK3R1 [cytosol] (Rattus norvegicus)
GRB2:GAB1 [cytosol] (Rattus norvegicus)
Gab1 [cytosol] (Rattus norvegicus)
GRB2:GAB1:PIK3R1 [cytosol] (Rattus norvegicus)
GRB2:GAB1 [cytosol] (Rattus norvegicus)
Gab1 [cytosol] (Rattus norvegicus)
Activated FGFR4:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA (Rattus norvegicus)
Activated FGFR4:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] (Rattus norvegicus)
Activated FGFR4:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Rattus norvegicus)
GRB2:GAB1:PIK3R1 [cytosol] (Rattus norvegicus)
GRB2:GAB1 [cytosol] (Rattus norvegicus)
Gab1 [cytosol] (Rattus norvegicus)
Activated FGFR4:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Rattus norvegicus)
GRB2:GAB1:PIK3R1 [cytosol] (Rattus norvegicus)
GRB2:GAB1 [cytosol] (Rattus norvegicus)
Gab1 [cytosol] (Rattus norvegicus)
Activated FGFR4:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 (Rattus norvegicus)
Activated FGFR4:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Rattus norvegicus)
GRB2:GAB1:PIK3R1 [cytosol] (Rattus norvegicus)
GRB2:GAB1 [cytosol] (Rattus norvegicus)
Gab1 [cytosol] (Rattus norvegicus)
GRB2:GAB1:PIK3R1 [cytosol] (Rattus norvegicus)
GRB2:GAB1 [cytosol] (Rattus norvegicus)
Gab1 [cytosol] (Rattus norvegicus)
Activated FGFR4:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1binds PIK3CA (Rattus norvegicus)
Activated FGFR4:p-FRS2:p-PTPN11:GRB2:GAB1:PI3K [plasma membrane] (Rattus norvegicus)
Activated FGFR4:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Rattus norvegicus)
GRB2:GAB1:PIK3R1 [cytosol] (Rattus norvegicus)
GRB2:GAB1 [cytosol] (Rattus norvegicus)
Gab1 [cytosol] (Rattus norvegicus)
Activated FGFR4:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Rattus norvegicus)
GRB2:GAB1:PIK3R1 [cytosol] (Rattus norvegicus)
GRB2:GAB1 [cytosol] (Rattus norvegicus)
Gab1 [cytosol] (Rattus norvegicus)
Binding of PIK3 regulatory alpha subunit to GRB2:GAB1 (Rattus norvegicus)
GRB2:GAB1 [cytosol] (Rattus norvegicus)
Gab1 [cytosol] (Rattus norvegicus)
GRB2:GAB1:PIK3R1 [cytosol] (Rattus norvegicus)
GRB2:GAB1 [cytosol] (Rattus norvegicus)
Gab1 [cytosol] (Rattus norvegicus)
FGFR4- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 (Rattus norvegicus)
Activated FGFR4:p-FRS2:p-PTPN11:GRB2:GAB1:PI3K [plasma membrane] (Rattus norvegicus)
Activated FGFR4:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Rattus norvegicus)
GRB2:GAB1:PIK3R1 [cytosol] (Rattus norvegicus)
GRB2:GAB1 [cytosol] (Rattus norvegicus)
Gab1 [cytosol] (Rattus norvegicus)
FGFR4-associated PI3K phosphorylates PIP2 to PIP3 (Rattus norvegicus)
Activated FGFR4:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] (Rattus norvegicus)
Activated FGFR4:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Rattus norvegicus)
GRB2:GAB1:PIK3R1 [cytosol] (Rattus norvegicus)
GRB2:GAB1 [cytosol] (Rattus norvegicus)
Gab1 [cytosol] (Rattus norvegicus)
Signaling by Insulin receptor (Rattus norvegicus)
Insulin receptor signalling cascade (Rattus norvegicus)
IRS-mediated signalling (Rattus norvegicus)
PI3K Cascade (Rattus norvegicus)
PI3K-containing complexes phosphorylate PIP2 to PIP3 (Rattus norvegicus)
PI3K-containing complexes [cytosol] (Rattus norvegicus)
Activated FGFR bound to PI3K [cytosol] (Rattus norvegicus)
GRB2 and GAB1 bound to activated FGFR and FRS2-alpha [plasma membrane] (Rattus norvegicus)
Gab1 [cytosol] (Rattus norvegicus)
Signaling by MET (Rattus norvegicus)
MET activates PI3K/AKT signaling (Rattus norvegicus)
Activated MET binds GAB1 (Rattus norvegicus)
Gab1 [cytosol] (Rattus norvegicus)
HGF:p-4Y-MET dimer:GAB1 [plasma membrane] (Rattus norvegicus)
Gab1 [cytosol] (Rattus norvegicus)
Activated MET binds GAB1 and GRB2 (Rattus norvegicus)
Gab1 [cytosol] (Rattus norvegicus)
HGF:p-4Y-MET dimer:GRB2-1:GAB1 [plasma membrane] (Rattus norvegicus)
Gab1 [cytosol] (Rattus norvegicus)
MET phosphorylates GAB1 (Rattus norvegicus)
HGF:p-4Y-MET dimer:GAB1,HGF:p-4Y-MET dimer:GRB2:GAB1 [plasma membrane] (Rattus norvegicus)
HGF:p-4Y-MET dimer:GAB1 [plasma membrane] (Rattus norvegicus)
Gab1 [cytosol] (Rattus norvegicus)
HGF:p-4Y-MET dimer:GRB2-1:GAB1 [plasma membrane] (Rattus norvegicus)
Gab1 [cytosol] (Rattus norvegicus)
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) (Rattus norvegicus)
IGF1R signaling cascade (Rattus norvegicus)
IRS-related events triggered by IGF1R (Rattus norvegicus)
IRS-mediated signalling (Rattus norvegicus)
PI3K Cascade (Rattus norvegicus)
PI3K-containing complexes phosphorylate PIP2 to PIP3 (Rattus norvegicus)
PI3K-containing complexes [cytosol] (Rattus norvegicus)
Activated FGFR bound to PI3K [cytosol] (Rattus norvegicus)
GRB2 and GAB1 bound to activated FGFR and FRS2-alpha [plasma membrane] (Rattus norvegicus)
Gab1 [cytosol] (Rattus norvegicus)
External Reference Information
External Reference
UniProt:D3ZAL7
Gene Names
Gab1
Reference Genes
ENSEMBL:ENSRNOG00000017879
UCSC:D3ZAL7 Gab1
Other Identifiers
10806927
1399167_a_at
17729005
361388
5633502
5698043
5781136
5804518
5899995
6100785
6141789
6394467
6458750
6496963
6654389
6671501
6672658
6678499
6699558
6740303
A_44_P176342
A_44_P494608
GE1136441
GE1250033
GO:0001525
GO:0005911
GO:0023052
GO:0038084
GO:0045766
GO:0048856
GO:0048870
GO:0090668
ILMN_1349894
PH_rn_0008607
rc_AA819647_at
rc_AA925305_g_at
Participates
as an input of
EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2 binds GAB1 (Rattus norvegicus)
Activated MET binds GAB1 and GRB2 (Rattus norvegicus)
Activated MET binds GAB1 (Rattus norvegicus)
Binding of GRB2 to GAB1 (Rattus norvegicus)
as a component of
EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:IRS2:GAB1 [plasma membrane] (Rattus norvegicus)
HGF:p-4Y-MET dimer:GAB1 [plasma membrane] (Rattus norvegicus)
HGF:p-4Y-MET dimer:GRB2-1:GAB1 [plasma membrane] (Rattus norvegicus)
GRB2 and GAB1 bound to activated FGFR and FRS2-alpha [plasma membrane] (Rattus norvegicus)
GRB2:GAB1 [cytosol] (Rattus norvegicus)
as a member of
GAB1,GAB2 [cytosol] (Rattus norvegicus)
Other forms of this molecule
phospho-Gab1 [cytosol]
phospho-Gab1 [cytosol]
phospho-Gab1 [cytosol]
Inferred From
GAB1 [cytosol]
(Homo sapiens)
Cross References
ENSEMBL
ENSRNOT00000024390
,
ENSRNOP00000024390
RGD
1311085
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