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What is Reactome ?
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Rbx1 [cytosol]
Stable Identifier
R-RNO-180582
Type
Protein [EntityWithAccessionedSequence]
Species
Rattus norvegicus
Compartment
cytosol
Synonyms
RBX1, A0A0G2JUC8
Locations in the PathwayBrowser
Expand all
Cell Cycle (Rattus norvegicus)
Cell Cycle, Mitotic (Rattus norvegicus)
Mitotic G2-G2/M phases (Rattus norvegicus)
G2/M Transition (Rattus norvegicus)
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis (Rattus norvegicus)
Formation of the SCF-FBXL7 complex (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
SKP1:CUL1:RBX1:FBXL7 [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
Proteasome degrades AURKA ubiquitinated by SCF-FBXL7 (Rattus norvegicus)
SCF-FBXL7:PolyUb-AURKA [cytosol] (Rattus norvegicus)
SKP1:CUL1:RBX1:FBXL7 [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
SKP1:CUL1:RBX1:FBXL7 [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
SCF-FBXL18 ubiquitinates FBXL7 (Rattus norvegicus)
SKP1:CUL1:RBX1:FBXL18 [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
SCF-FBXL7 ubiquitinates AURKA (Rattus norvegicus)
SCF-FBXL7:AURKA [cytosol] (Rattus norvegicus)
SKP1:CUL1:RBX1:FBXL7 [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
SCF-FBXL7:PolyUb-AURKA [cytosol] (Rattus norvegicus)
SKP1:CUL1:RBX1:FBXL7 [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
SKP1:CUL1:RBX1:FBXL7 [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
SCF:FBXL7 binds AURKA (Rattus norvegicus)
SCF-FBXL7:AURKA [cytosol] (Rattus norvegicus)
SKP1:CUL1:RBX1:FBXL7 [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
SKP1:CUL1:RBX1:FBXL7 [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
Cellular responses to stimuli (Rattus norvegicus)
Cellular responses to stress (Rattus norvegicus)
Cellular response to chemical stress (Rattus norvegicus)
KEAP1-NFE2L2 pathway (Rattus norvegicus)
CUL3:RBX1 ubiquitinates KEAP1 (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
SESN1,2:ub-K420 p-S349 SQSTM1 oligomer:KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Rattus norvegicus)
ub-K420 p-S349 SQSTM1 oligomer:KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Rattus norvegicus)
KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
SESN1,SESN2:ub-K420 p-S349 SQSTM1 oligomer:ub-KEAP1:CUL3:RBX1 [cytosol] (Rattus norvegicus)
ub-KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
KEAP1:CUL3:RBX1 ubiquitinates p-S349 SQSTM1 oligomer (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
p-S349 SQSTM1 oligomer:KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Rattus norvegicus)
KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
ub-K420 p-S349 SQSTM1 oligomer:KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Rattus norvegicus)
KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
KEAP1:NEDD8-CUL3:RBX1 complex ubiquitinates NFE2L2 (Rattus norvegicus)
KEAP1:NEDD8-CUL3:RBX1:NFE2L2 [cytosol] (Rattus norvegicus)
KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
NFE2L2 inducers:KEAP1:CUL3:RBX1:NFE2L2 [cytosol] (Rattus norvegicus)
KEAP1:NEDD8-CUL3:RBX1:NFE2L2 [cytosol] (Rattus norvegicus)
KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
ub-NFE2L2:KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Rattus norvegicus)
KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
MAP1LC3B binds KEAP1 and SQSTM1 (Rattus norvegicus)
MAP1LC3B:SESN1,SESN2:ub-K420 p-S349 SQSTM1 oligomer:ub-KEAP1:CUL3:RBX1 [cytosol] (Rattus norvegicus)
SESN1,SESN2:ub-K420 p-S349 SQSTM1 oligomer:ub-KEAP1:CUL3:RBX1 [cytosol] (Rattus norvegicus)
ub-KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
SESN1,SESN2:ub-K420 p-S349 SQSTM1 oligomer:ub-KEAP1:CUL3:RBX1 [cytosol] (Rattus norvegicus)
ub-KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
NFE2L2 inducers bind to KEAP1:CUL3:RBX1:NFE2L2 (Rattus norvegicus)
KEAP1:NEDD8-CUL3:RBX1:NFE2L2 [cytosol] (Rattus norvegicus)
KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
NFE2L2 inducers:KEAP1:CUL3:RBX1:NFE2L2 [cytosol] (Rattus norvegicus)
KEAP1:NEDD8-CUL3:RBX1:NFE2L2 [cytosol] (Rattus norvegicus)
KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
RBX1:CUL3 dissociates from forming autophagosome (Rattus norvegicus)
MAP1LC3B:SESN1,SESN2:ub-K420 p-S349 SQSTM1 oligomer:ub-KEAP1:CUL3:RBX1 [cytosol] (Rattus norvegicus)
SESN1,SESN2:ub-K420 p-S349 SQSTM1 oligomer:ub-KEAP1:CUL3:RBX1 [cytosol] (Rattus norvegicus)
ub-KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
NEDD8-CUL3:RBX1 [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
SESN1,SESN1 bind SQSTM1 and KEAP1 (Rattus norvegicus)
SESN1,2:ub-K420 p-S349 SQSTM1 oligomer:KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Rattus norvegicus)
ub-K420 p-S349 SQSTM1 oligomer:KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Rattus norvegicus)
KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
ub-K420 p-S349 SQSTM1 oligomer:KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Rattus norvegicus)
KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
UBXN7:UBF1:NPLOC4:VCP hexamer binds NFE2L2:CRL3 complex (Rattus norvegicus)
ub-NFE2L2:KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Rattus norvegicus)
KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
ub-NFE2L2:KEAP1:NEDD8-CUL3:RBX1:UBXN7:UBF1:NPLOC4:VCP hexamer [cytosol] (Rattus norvegicus)
ub-NFE2L2:KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Rattus norvegicus)
KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
Ubiquitinated NFE2L2 is extracted from CRL3 complex for degradation (Rattus norvegicus)
KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
ub-NFE2L2:KEAP1:NEDD8-CUL3:RBX1:UBXN7:UBF1:NPLOC4:VCP hexamer [cytosol] (Rattus norvegicus)
ub-NFE2L2:KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Rattus norvegicus)
KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
p-S349 SQSTM1 oligomer binds KEAP1:CUL3:RBX1 (Rattus norvegicus)
KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
p-S349 SQSTM1 oligomer:KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Rattus norvegicus)
KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
Cellular response to hypoxia (Rattus norvegicus)
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha (Rattus norvegicus)
Cytosolic PHD2,3 hydroxylates proline residues on HIF1A (Rattus norvegicus)
PHD2,3:LIMD1,AJUBA,WTIP:VHL:EloB:EloC:CUL2:RBX1 [cytosol] (Rattus norvegicus)
RBX1-CUL2-EloB,C-VHL [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
Cytosolic PHD2,3 hydroxylates proline residues on HIF3A (Rattus norvegicus)
PHD2,3:LIMD1,AJUBA,WTIP:VHL:EloB:EloC:CUL2:RBX1 [cytosol] (Rattus norvegicus)
RBX1-CUL2-EloB,C-VHL [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
Cytosolic VBC complex ubiquitinylates hydroxyprolyl-HIF-alpha (Rattus norvegicus)
hydroxyPro-HIF-alpha:VHL:EloB,C:CUL2:RBX1:LIMD1,AJUBA,WTIP:PHD2,3 [cytosol] (Rattus norvegicus)
PHD2,3:LIMD1,AJUBA,WTIP:VHL:EloB:EloC:CUL2:RBX1 [cytosol] (Rattus norvegicus)
RBX1-CUL2-EloB,C-VHL [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
ub-hydroxyPro-HIF-alpha:VHL:EloB:EloC:CUL2:RBX1:LIMD1,AJUBA,WTIF:PHD2,3 [cytosol] (Rattus norvegicus)
PHD2,3:LIMD1,AJUBA,WTIP:VHL:EloB:EloC:CUL2:RBX1 [cytosol] (Rattus norvegicus)
RBX1-CUL2-EloB,C-VHL [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
Cytosolic VHL:EloB,C:CUL2:RBX1 binds hydroxyprolyl-HIF-alpha (Rattus norvegicus)
PHD2,3:LIMD1,AJUBA,WTIP:VHL:EloB:EloC:CUL2:RBX1 [cytosol] (Rattus norvegicus)
RBX1-CUL2-EloB,C-VHL [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
hydroxyPro-HIF-alpha:VHL:EloB,C:CUL2:RBX1:LIMD1,AJUBA,WTIP:PHD2,3 [cytosol] (Rattus norvegicus)
PHD2,3:LIMD1,AJUBA,WTIP:VHL:EloB:EloC:CUL2:RBX1 [cytosol] (Rattus norvegicus)
RBX1-CUL2-EloB,C-VHL [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
Proteasome proteolyzes ub-HIF-alpha (Rattus norvegicus)
VBC complex (with or without LIMD1) [cytosol] (Rattus norvegicus)
PHD2,3:LIMD1,AJUBA,WTIP:VHL:EloB:EloC:CUL2:RBX1 [cytosol] (Rattus norvegicus)
RBX1-CUL2-EloB,C-VHL [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
RBX1-CUL2-EloB,C-VHL [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
ub-hydroxyPro-HIF-alpha:VCB (with or without LIMD1) [cytosol] (Rattus norvegicus)
ub-hydroxyPro-HIF-alpha:VHL:EloB:EloC:CUL2:RBX1 [cytosol] (Rattus norvegicus)
RBX1-CUL2-EloB,C-VHL [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
ub-hydroxyPro-HIF-alpha:VHL:EloB:EloC:CUL2:RBX1:LIMD1,AJUBA,WTIF:PHD2,3 [cytosol] (Rattus norvegicus)
PHD2,3:LIMD1,AJUBA,WTIP:VHL:EloB:EloC:CUL2:RBX1 [cytosol] (Rattus norvegicus)
RBX1-CUL2-EloB,C-VHL [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
ub-hydroxyPro-HIF-alpha:VHL:EloB,C:CUL2:RBX1 translocates from the nucleus to the cytosol (Rattus norvegicus)
ub-hydroxyPro-HIF-alpha:VHL:EloB:EloC:CUL2:RBX1 [cytosol] (Rattus norvegicus)
RBX1-CUL2-EloB,C-VHL [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
Immune System (Rattus norvegicus)
Adaptive Immune System (Rattus norvegicus)
Class I MHC mediated antigen processing & presentation (Rattus norvegicus)
Antigen processing: Ubiquitination & Proteasome degradation (Rattus norvegicus)
Interaction of E3 with substrate and E2-Ub complex (Rattus norvegicus)
Ag-substrate:E3:E2:Ub [cytosol] (Rattus norvegicus)
E3 ligases in proteasomal degradation [cytosol] (Rattus norvegicus)
RBX1-CUL2-EloB,C-VHL [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
RBX1-CUL5-EloB/C-SOCS [cytosol] (Rattus norvegicus)
Cul5-SCF complex [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
RBX1:CUL3:BTB [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
RBX1:CUL5:EloB/C:LRRC41 [cytosol] (Rattus norvegicus)
Cul5-SCF complex [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
RBX1:CUL7:SKP1:FBXW8:GLMN [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
SCF E3 ubiquitin ligase [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
E3 ligases in proteasomal degradation [cytosol] (Rattus norvegicus)
RBX1-CUL2-EloB,C-VHL [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
RBX1-CUL5-EloB/C-SOCS [cytosol] (Rattus norvegicus)
Cul5-SCF complex [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
RBX1:CUL3:BTB [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
RBX1:CUL5:EloB/C:LRRC41 [cytosol] (Rattus norvegicus)
Cul5-SCF complex [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
RBX1:CUL7:SKP1:FBXW8:GLMN [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
SCF E3 ubiquitin ligase [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
Polyubiquitination of substrate (Rattus norvegicus)
E3 ligases in proteasomal degradation [cytosol] (Rattus norvegicus)
RBX1-CUL2-EloB,C-VHL [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
RBX1-CUL5-EloB/C-SOCS [cytosol] (Rattus norvegicus)
Cul5-SCF complex [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
RBX1:CUL3:BTB [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
RBX1:CUL5:EloB/C:LRRC41 [cytosol] (Rattus norvegicus)
Cul5-SCF complex [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
RBX1:CUL7:SKP1:FBXW8:GLMN [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
SCF E3 ubiquitin ligase [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
E3:K48-polyubiquitinated substrate [cytosol] (Rattus norvegicus)
E3 ligases in proteasomal degradation [cytosol] (Rattus norvegicus)
RBX1-CUL2-EloB,C-VHL [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
RBX1-CUL5-EloB/C-SOCS [cytosol] (Rattus norvegicus)
Cul5-SCF complex [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
RBX1:CUL3:BTB [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
RBX1:CUL5:EloB/C:LRRC41 [cytosol] (Rattus norvegicus)
Cul5-SCF complex [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
RBX1:CUL7:SKP1:FBXW8:GLMN [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
SCF E3 ubiquitin ligase [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
E3:Ub:substrate [cytosol] (Rattus norvegicus)
E3 ligases in proteasomal degradation [cytosol] (Rattus norvegicus)
RBX1-CUL2-EloB,C-VHL [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
RBX1-CUL5-EloB/C-SOCS [cytosol] (Rattus norvegicus)
Cul5-SCF complex [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
RBX1:CUL3:BTB [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
RBX1:CUL5:EloB/C:LRRC41 [cytosol] (Rattus norvegicus)
Cul5-SCF complex [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
RBX1:CUL7:SKP1:FBXW8:GLMN [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
SCF E3 ubiquitin ligase [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
Release of E3 from polyubiquitinated substrate (Rattus norvegicus)
E3 ligases in proteasomal degradation [cytosol] (Rattus norvegicus)
RBX1-CUL2-EloB,C-VHL [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
RBX1-CUL5-EloB/C-SOCS [cytosol] (Rattus norvegicus)
Cul5-SCF complex [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
RBX1:CUL3:BTB [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
RBX1:CUL5:EloB/C:LRRC41 [cytosol] (Rattus norvegicus)
Cul5-SCF complex [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
RBX1:CUL7:SKP1:FBXW8:GLMN [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
SCF E3 ubiquitin ligase [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
E3:K48-polyubiquitinated substrate [cytosol] (Rattus norvegicus)
E3 ligases in proteasomal degradation [cytosol] (Rattus norvegicus)
RBX1-CUL2-EloB,C-VHL [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
RBX1-CUL5-EloB/C-SOCS [cytosol] (Rattus norvegicus)
Cul5-SCF complex [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
RBX1:CUL3:BTB [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
RBX1:CUL5:EloB/C:LRRC41 [cytosol] (Rattus norvegicus)
Cul5-SCF complex [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
RBX1:CUL7:SKP1:FBXW8:GLMN [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
SCF E3 ubiquitin ligase [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
Transfer of Ub from E2 to substrate and release of E2 (Rattus norvegicus)
Ag-substrate:E3:E2:Ub [cytosol] (Rattus norvegicus)
E3 ligases in proteasomal degradation [cytosol] (Rattus norvegicus)
RBX1-CUL2-EloB,C-VHL [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
RBX1-CUL5-EloB/C-SOCS [cytosol] (Rattus norvegicus)
Cul5-SCF complex [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
RBX1:CUL3:BTB [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
RBX1:CUL5:EloB/C:LRRC41 [cytosol] (Rattus norvegicus)
Cul5-SCF complex [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
RBX1:CUL7:SKP1:FBXW8:GLMN [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
SCF E3 ubiquitin ligase [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
E3 ligases in proteasomal degradation [cytosol] (Rattus norvegicus)
RBX1-CUL2-EloB,C-VHL [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
RBX1-CUL5-EloB/C-SOCS [cytosol] (Rattus norvegicus)
Cul5-SCF complex [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
RBX1:CUL3:BTB [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
RBX1:CUL5:EloB/C:LRRC41 [cytosol] (Rattus norvegicus)
Cul5-SCF complex [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
RBX1:CUL7:SKP1:FBXW8:GLMN [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
SCF E3 ubiquitin ligase [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
E3:Ub:substrate [cytosol] (Rattus norvegicus)
E3 ligases in proteasomal degradation [cytosol] (Rattus norvegicus)
RBX1-CUL2-EloB,C-VHL [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
RBX1-CUL5-EloB/C-SOCS [cytosol] (Rattus norvegicus)
Cul5-SCF complex [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
RBX1:CUL3:BTB [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
RBX1:CUL5:EloB/C:LRRC41 [cytosol] (Rattus norvegicus)
Cul5-SCF complex [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
RBX1:CUL7:SKP1:FBXW8:GLMN [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
SCF E3 ubiquitin ligase [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
Cytokine Signaling in Immune system (Rattus norvegicus)
Prolactin receptor signaling (Rattus norvegicus)
PRLR binds SCF beta-TrCP complex (Rattus norvegicus)
BTRC:CUL1:RBX1:SKP1 [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
PRLR ligands:p-S349- PRLR:JAK2 dimer:SCF beta-TrCP complex [plasma membrane] (Rattus norvegicus)
BTRC:CUL1:RBX1:SKP1 [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
Prolactin receptor is internalized (Rattus norvegicus)
BTRC:CUL1:RBX1:SKP1 [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
PRLR ligands:p-S349- PRLR:JAK2 dimer:SCF beta-TrCP complex [plasma membrane] (Rattus norvegicus)
BTRC:CUL1:RBX1:SKP1 [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
Prolactin receptor ligands bind the prolactin receptor (Rattus norvegicus)
PRLR ligands:p-S349- PRLR:JAK2 dimer:SCF beta-TrCP complex [plasma membrane] (Rattus norvegicus)
BTRC:CUL1:RBX1:SKP1 [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
Signaling by Interleukins (Rattus norvegicus)
Interleukin-1 family signaling (Rattus norvegicus)
Interleukin-1 signaling (Rattus norvegicus)
Beta-TrCP ubiquitinates NFKB p50:p65:phospho IKBA complex (Rattus norvegicus)
BTRC:CUL1:RBX1:SKP1 [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
BTRC:CUL1:RBX1:SKP1:NFKB1:RELA:p-S32,S36-NFKBIA:Ub [cytosol] (Rattus norvegicus)
BTRC:CUL1:RBX1:SKP1 [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
NFKB1(1-433):RELA:p-S32,S36-NFKBIA:BTRC:CUL1:RBX1:SKP1 [cytosol] (Rattus norvegicus)
BTRC:CUL1:RBX1:SKP1 [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
Metabolism of proteins (Rattus norvegicus)
Post-translational protein modification (Rattus norvegicus)
Neddylation (Rattus norvegicus)
26S proteasome degrades HIFalpha (Rattus norvegicus)
RBX1:NEDD8-CUL2:EloB,C:VHL:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
ub-hydroxyPro-HIF-alpha:VHL:EloB:EloC:NEDD8-CUL2:RBX1:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Rattus norvegicus)
RBX1:NEDD8-CUL2:EloB,C:VHL:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
AcM-UBE2M transfers NEDD8 to CRL1 E3 ubiquitin ligase complex (Rattus norvegicus)
CRL1 E3 ubiquitin ligase complex:MyrG-DCUN1D3 [plasma membrane] (Rattus norvegicus)
CRL1 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Rattus norvegicus)
SCF E3 ubiquitin ligase [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
NEDD8-AcM-UBE2M:CRL1 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Rattus norvegicus)
CRL1 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Rattus norvegicus)
SCF E3 ubiquitin ligase [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
NEDD8-CRL1 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Rattus norvegicus)
NEDD8-CRL1 E3 ligase complex [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
AcM-UBE2M transfers NEDD8 to CRL2 E3 ubiquitin ligase complex (Rattus norvegicus)
NEDD8-AcM-UBE2M:CRL2 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Rattus norvegicus)
CRL2 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Rattus norvegicus)
CRL2 E3 ubiquitin ligase [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
NEDD8-CRL2 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Rattus norvegicus)
NEDD8-CRL2 E3 ligase complex [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
AcM-UBE2M transfers NEDD8 to CRL3 E3 ubiquitin ligase complex (Rattus norvegicus)
NEDD8-AcM-UBE2M:CRL3 E3 ubiquitin ligase :DCUN1D1,2,4,5 [cytosol] (Rattus norvegicus)
CRL3 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Rattus norvegicus)
RBX1:CUL3:BTB [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
NEDD8-CRL3 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Rattus norvegicus)
NEDD8-CUL3:RBX1:BTB [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
AcM-UBE2M transfers NEDD8 to CUL9:RBX1 (Rattus norvegicus)
NEDD8-AcM-UBE2M:CUL9:RBX1 [cytosol] (Rattus norvegicus)
CUL9:RBX1 [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
NEDD8-CUL9:RBX1 [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
CAND1 binds cytosolic CRL E3 ubiquitin ligases (Rattus norvegicus)
CRL E3 ubiquitin ligase:CAND1 [cytosol] (Rattus norvegicus)
CRL E3 ubiquitin ligases [cytosol] (Rattus norvegicus)
CRL2 E3 ubiquitin ligase [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
RBX1:CUL3:BTB [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
SCF E3 ubiquitin ligase [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
CRL E3 ubiquitin ligases [cytosol] (Rattus norvegicus)
CRL2 E3 ubiquitin ligase [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
RBX1:CUL3:BTB [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
SCF E3 ubiquitin ligase [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
COMMDs displace CAND1 from cytosolic CRL E3 ubiquitin ligase complexes (Rattus norvegicus)
CRL E3 ubiquitin ligase:CAND1 [cytosol] (Rattus norvegicus)
CRL E3 ubiquitin ligases [cytosol] (Rattus norvegicus)
CRL2 E3 ubiquitin ligase [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
RBX1:CUL3:BTB [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
SCF E3 ubiquitin ligase [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
CRL E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Rattus norvegicus)
CRL1 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Rattus norvegicus)
SCF E3 ubiquitin ligase [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
CRL2 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Rattus norvegicus)
CRL2 E3 ubiquitin ligase [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
CRL3 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Rattus norvegicus)
RBX1:CUL3:BTB [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes (Rattus norvegicus)
CRL E3 ubiquitin ligase complex:COMMDs:CCDC22:DCUN1Ds [cytosol] (Rattus norvegicus)
CRL1 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Rattus norvegicus)
SCF E3 ubiquitin ligase [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
CRL2 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Rattus norvegicus)
CRL2 E3 ubiquitin ligase [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
CRL3 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Rattus norvegicus)
RBX1:CUL3:BTB [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
NEDD8 CRL E3 ubiquitin ligases:COMMDs:CCDC22:DCUN1Ds [cytosol] (Rattus norvegicus)
NEDD8-CRL1 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Rattus norvegicus)
NEDD8-CRL1 E3 ligase complex [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
NEDD8-CRL2 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Rattus norvegicus)
NEDD8-CRL2 E3 ligase complex [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
NEDD8-CRL3 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Rattus norvegicus)
NEDD8-CUL3:RBX1:BTB [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
CUL9:RBX1 ubiquitinates BIRC5 (Rattus norvegicus)
NEDD8-CUL9:RBX1 [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
NEDD8-CUL9:RBX1:CUL7:CCDC8:OBSL1 [cytosol] (Rattus norvegicus)
NEDD8-CUL9:RBX1 [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
KEAP1:NEDD8-CUL3:RBX1 complex ubiquitinates NFE2L2 (Rattus norvegicus)
KEAP1:NEDD8-CUL3:RBX1:NFE2L2 [cytosol] (Rattus norvegicus)
KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
NFE2L2 inducers:KEAP1:CUL3:RBX1:NFE2L2 [cytosol] (Rattus norvegicus)
KEAP1:NEDD8-CUL3:RBX1:NFE2L2 [cytosol] (Rattus norvegicus)
KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
ub-NFE2L2:KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Rattus norvegicus)
KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
MyrG-DCUN1D3 binds CRL1 E3 ubiquitin ligase complex (Rattus norvegicus)
CRL1 E3 ubiquitin ligase complex:MyrG-DCUN1D3 [plasma membrane] (Rattus norvegicus)
CRL1 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Rattus norvegicus)
SCF E3 ubiquitin ligase [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
CRL1 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Rattus norvegicus)
SCF E3 ubiquitin ligase [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
NEDD8-CUL9:RBX1 binds CUL7:CCDC8:OBSL1 (Rattus norvegicus)
NEDD8-CUL9:RBX1 [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
NEDD8-CUL9:RBX1:CUL7:CCDC8:OBSL1 [cytosol] (Rattus norvegicus)
NEDD8-CUL9:RBX1 [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
NEDD8:AcM-UBE2M binds CRL1 E3 ubiquitin ligase complex (Rattus norvegicus)
CRL1 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Rattus norvegicus)
SCF E3 ubiquitin ligase [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
NEDD8-AcM-UBE2M:CRL1 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Rattus norvegicus)
CRL1 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Rattus norvegicus)
SCF E3 ubiquitin ligase [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
NEDD8:AcM-UBE2M binds CRL2 E3 ubiquitin ligase complex (Rattus norvegicus)
CRL2 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Rattus norvegicus)
CRL2 E3 ubiquitin ligase [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
NEDD8-AcM-UBE2M:CRL2 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Rattus norvegicus)
CRL2 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Rattus norvegicus)
CRL2 E3 ubiquitin ligase [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
NEDD8:AcM-UBE2M binds CRL3 E3 ubiquitin ligase complex (Rattus norvegicus)
CRL3 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Rattus norvegicus)
RBX1:CUL3:BTB [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
NEDD8-AcM-UBE2M:CRL3 E3 ubiquitin ligase :DCUN1D1,2,4,5 [cytosol] (Rattus norvegicus)
CRL3 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Rattus norvegicus)
RBX1:CUL3:BTB [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
NEDD8:AcM-UBE2M binds CUL9:RBX1 ubiquitin ligase complex (Rattus norvegicus)
CUL9:RBX1 [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
NEDD8-AcM-UBE2M:CUL9:RBX1 [cytosol] (Rattus norvegicus)
CUL9:RBX1 [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
UBXN7:UBF1:NPLOC4:VCP hexamer binds NFE2L2:CRL3 complex (Rattus norvegicus)
ub-NFE2L2:KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Rattus norvegicus)
KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
ub-NFE2L2:KEAP1:NEDD8-CUL3:RBX1:UBXN7:UBF1:NPLOC4:VCP hexamer [cytosol] (Rattus norvegicus)
ub-NFE2L2:KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Rattus norvegicus)
KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
Ubiquitinated NFE2L2 is extracted from CRL3 complex for degradation (Rattus norvegicus)
KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
ub-NFE2L2:KEAP1:NEDD8-CUL3:RBX1:UBXN7:UBF1:NPLOC4:VCP hexamer [cytosol] (Rattus norvegicus)
ub-NFE2L2:KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Rattus norvegicus)
KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
VHL:EloB,C:NEDD8-CUL2:RBX1 complex binds UBXN7 (Rattus norvegicus)
RBX1:NEDD8-CUL2:EloB,C:VHL:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
RBX1:NEDD8-CUL2:EloB,C:VHL:COMMDs:CCDC22:DCUN1D1,2,4,5:UBXN7 [cytosol] (Rattus norvegicus)
RBX1:NEDD8-CUL2:EloB,C:VHL:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
VHL:EloB,C:NEDD8-CUL2:RBX1 complex binds hydroxyprolyl-HIF-alpha (Rattus norvegicus)
RBX1:NEDD8-CUL2:EloB,C:VHL:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
RBX1:NEDD8-CUL2:EloB,C:VHL:COMMDs:CCDC22:DCUN1D1,2,4,5:hydroxyPro-HIF-alpha [cytosol] (Rattus norvegicus)
RBX1:NEDD8-CUL2:EloB,C:VHL:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
VHL:EloB,C:NEDD8-CUL2:RBX1 complex ubiquitinylates HIF-alpha (Rattus norvegicus)
RBX1:NEDD8-CUL2:EloB,C:VHL:COMMDs:CCDC22:DCUN1D1,2,4,5:UBXN7 [cytosol] (Rattus norvegicus)
RBX1:NEDD8-CUL2:EloB,C:VHL:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
RBX1:NEDD8-CUL2:EloB,C:VHL:COMMDs:CCDC22:DCUN1D1,2,4,5:hydroxyPro-HIF-alpha [cytosol] (Rattus norvegicus)
RBX1:NEDD8-CUL2:EloB,C:VHL:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
ub-hydroxyPro-HIF-alpha:VHL:EloB:EloC:NEDD8-CUL2:RBX1:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Rattus norvegicus)
RBX1:NEDD8-CUL2:EloB,C:VHL:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
Signal Transduction (Rattus norvegicus)
MAPK family signaling cascades (Rattus norvegicus)
MAPK1/MAPK3 signaling (Rattus norvegicus)
RAF/MAP kinase cascade (Rattus norvegicus)
Regulation of RAS by GAPs (Rattus norvegicus)
KBTBD7:CUL3:RBX1 ubiquitinates NF1 (Rattus norvegicus)
KBTBD7:CUL3:RBX1 [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
Signaling by Hedgehog (Rattus norvegicus)
Hedgehog 'off' state (Rattus norvegicus)
Degradation of GLI1 by the proteasome (Rattus norvegicus)
SCF(beta-TrCP) ubiquitinates p-GLI1 (Rattus norvegicus)
BTRC:CUL1:RBX1:SKP1 [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
GLI3 is processed to GLI3R by the proteasome (Rattus norvegicus)
SCF(beta-TrCP) ubiquitinates p-GLI3 (Rattus norvegicus)
BTRC:CUL1:RBX1:SKP1 [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
Signaling by WNT (Rattus norvegicus)
Degradation of beta-catenin by the destruction complex (Rattus norvegicus)
Association of beta-catenin with the RBX1:SCF(beta-TrCP1) ubiquitin ligase complex (Rattus norvegicus)
BTRC:CUL1:RBX1:SKP1 [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
RBX1:SKP1:CUL1:beta-TrCP1:phosphorylated beta-catenin complex [cytosol] (Rattus norvegicus)
BTRC:CUL1:RBX1:SKP1 [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
Degradation of ubiquitinated beta catenin by the proteasome (Rattus norvegicus)
BTRC:CUL1:RBX1:SKP1 [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
ubiquitinated phospho-beta-catenin:RBX1:SCF(beta-TrCP1) complex [cytosol] (Rattus norvegicus)
RBX1:SKP1:CUL1:beta-TrCP1:phosphorylated beta-catenin complex [cytosol] (Rattus norvegicus)
BTRC:CUL1:RBX1:SKP1 [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
Multi-ubiquitination of phospho-beta-catenin by RBX1:SCF(beta-TrCP1) (Rattus norvegicus)
RBX1:SKP1:CUL1:beta-TrCP1:phosphorylated beta-catenin complex [cytosol] (Rattus norvegicus)
BTRC:CUL1:RBX1:SKP1 [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
ubiquitinated phospho-beta-catenin:RBX1:SCF(beta-TrCP1) complex [cytosol] (Rattus norvegicus)
RBX1:SKP1:CUL1:beta-TrCP1:phosphorylated beta-catenin complex [cytosol] (Rattus norvegicus)
BTRC:CUL1:RBX1:SKP1 [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
TCF dependent signaling in response to WNT (Rattus norvegicus)
Degradation of DVL (Rattus norvegicus)
DVL is bound by the CUL3:KLHL12:RBX1 ubiquitin ligase complex (Rattus norvegicus)
CUL3:KLHL12:RBX1 [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
DVL:CUL3:KLHL12:RBX1 [cytosol] (Rattus norvegicus)
CUL3:KLHL12:RBX1 [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
DVL is ubiquitinated by CUL3:KLHL12:RBX1 (Rattus norvegicus)
DVL:CUL3:KLHL12:RBX1 [cytosol] (Rattus norvegicus)
CUL3:KLHL12:RBX1 [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
ub-DVL:CUL3:KLHL12:RBX1 [cytosol] (Rattus norvegicus)
CUL3:KLHL12:RBX1 [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
Ubiquitinated DVL is degraded by the proteasome (Rattus norvegicus)
CUL3:KLHL12:RBX1 [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
ub-DVL:CUL3:KLHL12:RBX1 [cytosol] (Rattus norvegicus)
CUL3:KLHL12:RBX1 [cytosol] (Rattus norvegicus)
Rbx1 [cytosol] (Rattus norvegicus)
External Reference Information
External Reference
UniProt:A0A0G2JUC8
Gene Names
Rbx1
Reference Genes
ENSEMBL:ENSRNOG00000058914
ENSEMBL:ENSRNOG00000058914.2 Rbx1
Other Identifiers
10897912
1388333_at
1388538_at
17830895
300084
5690138
5752661
6044809
6082705
6393732
6397304
6445877
A_44_P225259
A_64_P009848
GE1116548
GO:0008270
PH_rn_0006618
PH_rn_0019418
rc_AA850733_g_at
rc_AI070865_at
rc_AI072683_at
rc_AI104143_at
Participates
as a component of
RBX1:NEDD8-CUL2:EloB,C:VHL:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Rattus norvegicus)
NEDD8-CUL3:RBX1 [cytosol] (Rattus norvegicus)
NEDD8-CUL9:RBX1 [cytosol] (Rattus norvegicus)
CUL9:RBX1 [cytosol] (Rattus norvegicus)
CRL2 E3 ubiquitin ligase [cytosol] (Rattus norvegicus)
NEDD8-CRL1 E3 ligase complex [cytosol] (Rattus norvegicus)
NEDD8-CUL3:RBX1:BTB [cytosol] (Rattus norvegicus)
NEDD8-CRL2 E3 ligase complex [cytosol] (Rattus norvegicus)
KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Rattus norvegicus)
ub-KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Rattus norvegicus)
SKP1:CUL1:RBX1:FBXL18 [cytosol] (Rattus norvegicus)
SKP1:CUL1:RBX1:FBXL7 [cytosol] (Rattus norvegicus)
BTRC:CUL1:RBX1:SKP1 [cytosol] (Rattus norvegicus)
CUL3:KLHL12:RBX1 [cytosol] (Rattus norvegicus)
KBTBD7:CUL3:RBX1 [cytosol] (Rattus norvegicus)
SCF E3 ubiquitin ligase [cytosol] (Rattus norvegicus)
RBX1:CUL3:BTB [cytosol] (Rattus norvegicus)
RBX1-CUL2-EloB,C-VHL [cytosol] (Rattus norvegicus)
RBX1:CUL7:SKP1:FBXW8:GLMN [cytosol] (Rattus norvegicus)
Cul5-SCF complex [cytosol] (Rattus norvegicus)
as an input of
Formation of the SCF-FBXL7 complex (Rattus norvegicus)
Other forms of this molecule
Rbx1 [nucleoplasm]
Inferred From
RBX1 [cytosol]
(Homo sapiens)
Cross References
Ensembl
ENSRNOG00000058914
,
ENSRNOP00000069049
,
ENSRNOT00000086603
RGD
1308453
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