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Pdgfa [extracellular region]
Stable Identifier
R-RNO-184199
Type
Protein [EntityWithAccessionedSequence]
Species
Rattus norvegicus
Compartment
extracellular region
Synonyms
PDGFA-1, P28576
Locations in the PathwayBrowser
Expand all
Hemostasis (Rattus norvegicus)
Platelet activation, signaling and aggregation (Rattus norvegicus)
Response to elevated platelet cytosolic Ca2+ (Rattus norvegicus)
Platelet degranulation (Rattus norvegicus)
Exocytosis of platelet alpha granule contents (Rattus norvegicus)
Platelet alpha granule contents [extracellular region] (Rattus norvegicus)
PDGF dimer [extracellular region] (Rattus norvegicus)
PDGF AB heterodimer [extracellular region] (Rattus norvegicus)
Pdgfa [extracellular region] (Rattus norvegicus)
active PDGF-AA dimer [extracellular region] (Rattus norvegicus)
Pdgfa [extracellular region] (Rattus norvegicus)
Signal Transduction (Rattus norvegicus)
Intracellular signaling by second messengers (Rattus norvegicus)
PIP3 activates AKT signaling (Rattus norvegicus)
Negative regulation of the PI3K/AKT network (Rattus norvegicus)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Rattus norvegicus)
PI3K phosphorylates PIP2 to PIP3 (Rattus norvegicus)
Activator:PI3K [plasma membrane] (Rattus norvegicus)
PDGF:Phospho-PDGF receptor dimer:PI3K [plasma membrane] (Rattus norvegicus)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Rattus norvegicus)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Rattus norvegicus)
active PDGF-AA dimer [extracellular region] (Rattus norvegicus)
Pdgfa [extracellular region] (Rattus norvegicus)
PI3K phosphorylates PIP2 to PIP3 (Rattus norvegicus)
Activator:PI3K [plasma membrane] (Rattus norvegicus)
PDGF:Phospho-PDGF receptor dimer:PI3K [plasma membrane] (Rattus norvegicus)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Rattus norvegicus)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Rattus norvegicus)
active PDGF-AA dimer [extracellular region] (Rattus norvegicus)
Pdgfa [extracellular region] (Rattus norvegicus)
MAPK family signaling cascades (Rattus norvegicus)
MAPK1/MAPK3 signaling (Rattus norvegicus)
RAF/MAP kinase cascade (Rattus norvegicus)
RAS GEFs promote RAS nucleotide exchange (Rattus norvegicus)
RAS GEFs [plasma membrane] (Rattus norvegicus)
PDGF:Phospho-PDGF receptor dimer:Grb2:Sos1 [plasma membrane] (Rattus norvegicus)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Rattus norvegicus)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Rattus norvegicus)
active PDGF-AA dimer [extracellular region] (Rattus norvegicus)
Pdgfa [extracellular region] (Rattus norvegicus)
Signaling by Receptor Tyrosine Kinases (Rattus norvegicus)
Signaling by PDGF (Rattus norvegicus)
Autophosphorylation of PDGF alpha receptors (Rattus norvegicus)
PDGF alpha receptor: PDGF dimers [plasma membrane] (Rattus norvegicus)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Rattus norvegicus)
active PDGF-AA dimer [extracellular region] (Rattus norvegicus)
Pdgfa [extracellular region] (Rattus norvegicus)
PDGFR:type I PDGFR-binding TKIs [plasma membrane] (Rattus norvegicus)
PDGF alpha receptor: PDGF dimers [plasma membrane] (Rattus norvegicus)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Rattus norvegicus)
active PDGF-AA dimer [extracellular region] (Rattus norvegicus)
Pdgfa [extracellular region] (Rattus norvegicus)
Phospho PDGF alpha receptor:PDGF dimers [plasma membrane] (Rattus norvegicus)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Rattus norvegicus)
active PDGF-AA dimer [extracellular region] (Rattus norvegicus)
Pdgfa [extracellular region] (Rattus norvegicus)
Downstream signal transduction (Rattus norvegicus)
Activated PLC gamma dissociates from the PDGF receptor (Rattus norvegicus)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Rattus norvegicus)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Rattus norvegicus)
active PDGF-AA dimer [extracellular region] (Rattus norvegicus)
Pdgfa [extracellular region] (Rattus norvegicus)
PDGF:p-PDGFR dimer:p-PLCgamma [plasma membrane] (Rattus norvegicus)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Rattus norvegicus)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Rattus norvegicus)
active PDGF-AA dimer [extracellular region] (Rattus norvegicus)
Pdgfa [extracellular region] (Rattus norvegicus)
Activation of Src (Rattus norvegicus)
PDGF:Phospho-PDGF receptor dimer:MyrG-SRC [plasma membrane] (Rattus norvegicus)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Rattus norvegicus)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Rattus norvegicus)
active PDGF-AA dimer [extracellular region] (Rattus norvegicus)
Pdgfa [extracellular region] (Rattus norvegicus)
PDGF:Phospho-PDGF receptor dimer:MyrG-p-Y419-SRC [plasma membrane] (Rattus norvegicus)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Rattus norvegicus)
active PDGF-AA dimer [extracellular region] (Rattus norvegicus)
Pdgfa [extracellular region] (Rattus norvegicus)
Crk binds to the active PDGF receptor (Rattus norvegicus)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Rattus norvegicus)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Rattus norvegicus)
active PDGF-AA dimer [extracellular region] (Rattus norvegicus)
Pdgfa [extracellular region] (Rattus norvegicus)
PDGF:Phospho-PDGF receptor dimer:Crk [plasma membrane] (Rattus norvegicus)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Rattus norvegicus)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Rattus norvegicus)
active PDGF-AA dimer [extracellular region] (Rattus norvegicus)
Pdgfa [extracellular region] (Rattus norvegicus)
GRB2:SOS1 complex binds to the active receptor (Rattus norvegicus)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Rattus norvegicus)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Rattus norvegicus)
active PDGF-AA dimer [extracellular region] (Rattus norvegicus)
Pdgfa [extracellular region] (Rattus norvegicus)
PDGF:Phospho-PDGF receptor dimer:Grb2:Sos1 [plasma membrane] (Rattus norvegicus)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Rattus norvegicus)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Rattus norvegicus)
active PDGF-AA dimer [extracellular region] (Rattus norvegicus)
Pdgfa [extracellular region] (Rattus norvegicus)
Grb7 binds to the active PDGF receptor (Rattus norvegicus)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Rattus norvegicus)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Rattus norvegicus)
active PDGF-AA dimer [extracellular region] (Rattus norvegicus)
Pdgfa [extracellular region] (Rattus norvegicus)
PDGF:Phospho-PDGF receptor dimer:Grb7 [plasma membrane] (Rattus norvegicus)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Rattus norvegicus)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Rattus norvegicus)
active PDGF-AA dimer [extracellular region] (Rattus norvegicus)
Pdgfa [extracellular region] (Rattus norvegicus)
Nck binds to the active PDGF receptor (Rattus norvegicus)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Rattus norvegicus)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Rattus norvegicus)
active PDGF-AA dimer [extracellular region] (Rattus norvegicus)
Pdgfa [extracellular region] (Rattus norvegicus)
PDGF:Phospho-PDGFR receptor dimer:Nck [plasma membrane] (Rattus norvegicus)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Rattus norvegicus)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Rattus norvegicus)
active PDGF-AA dimer [extracellular region] (Rattus norvegicus)
Pdgfa [extracellular region] (Rattus norvegicus)
PI3-kinase binds to the active receptor (Rattus norvegicus)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Rattus norvegicus)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Rattus norvegicus)
active PDGF-AA dimer [extracellular region] (Rattus norvegicus)
Pdgfa [extracellular region] (Rattus norvegicus)
PDGF:Phospho-PDGF receptor dimer:PI3K [plasma membrane] (Rattus norvegicus)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Rattus norvegicus)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Rattus norvegicus)
active PDGF-AA dimer [extracellular region] (Rattus norvegicus)
Pdgfa [extracellular region] (Rattus norvegicus)
PI3K catalyses the phosphorylation of PIP2 to PIP3 (Rattus norvegicus)
PDGF:Phospho-PDGF receptor dimer:PI3K [plasma membrane] (Rattus norvegicus)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Rattus norvegicus)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Rattus norvegicus)
active PDGF-AA dimer [extracellular region] (Rattus norvegicus)
Pdgfa [extracellular region] (Rattus norvegicus)
PLC-gamma binds to the active receptor (Rattus norvegicus)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Rattus norvegicus)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Rattus norvegicus)
active PDGF-AA dimer [extracellular region] (Rattus norvegicus)
Pdgfa [extracellular region] (Rattus norvegicus)
PDGF:Phospho-PDGF receptor dimer:PLC-gamma [plasma membrane] (Rattus norvegicus)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Rattus norvegicus)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Rattus norvegicus)
active PDGF-AA dimer [extracellular region] (Rattus norvegicus)
Pdgfa [extracellular region] (Rattus norvegicus)
Phosphorylation of PLCgamma by PDGFR (Rattus norvegicus)
PDGF:Phospho-PDGF receptor dimer:PLC-gamma [plasma membrane] (Rattus norvegicus)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Rattus norvegicus)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Rattus norvegicus)
active PDGF-AA dimer [extracellular region] (Rattus norvegicus)
Pdgfa [extracellular region] (Rattus norvegicus)
PDGF:p-PDGFR dimer:p-PLCgamma [plasma membrane] (Rattus norvegicus)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Rattus norvegicus)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Rattus norvegicus)
active PDGF-AA dimer [extracellular region] (Rattus norvegicus)
Pdgfa [extracellular region] (Rattus norvegicus)
SH2 domain of Src binds to the active receptor (Rattus norvegicus)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Rattus norvegicus)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Rattus norvegicus)
active PDGF-AA dimer [extracellular region] (Rattus norvegicus)
Pdgfa [extracellular region] (Rattus norvegicus)
PDGF:Phospho-PDGF receptor dimer:MyrG-SRC [plasma membrane] (Rattus norvegicus)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Rattus norvegicus)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Rattus norvegicus)
active PDGF-AA dimer [extracellular region] (Rattus norvegicus)
Pdgfa [extracellular region] (Rattus norvegicus)
SHP2 binds to the active receptor (Rattus norvegicus)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Rattus norvegicus)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Rattus norvegicus)
active PDGF-AA dimer [extracellular region] (Rattus norvegicus)
Pdgfa [extracellular region] (Rattus norvegicus)
PDGF:Phospho-PDGF receptor dimer:SHP2 [plasma membrane] (Rattus norvegicus)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Rattus norvegicus)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Rattus norvegicus)
active PDGF-AA dimer [extracellular region] (Rattus norvegicus)
Pdgfa [extracellular region] (Rattus norvegicus)
SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS) (Rattus norvegicus)
PDGF:Phospho-PDGF receptor dimer:Grb2:Sos1 [plasma membrane] (Rattus norvegicus)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Rattus norvegicus)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Rattus norvegicus)
active PDGF-AA dimer [extracellular region] (Rattus norvegicus)
Pdgfa [extracellular region] (Rattus norvegicus)
STAT binds to the active receptor (Rattus norvegicus)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Rattus norvegicus)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Rattus norvegicus)
active PDGF-AA dimer [extracellular region] (Rattus norvegicus)
Pdgfa [extracellular region] (Rattus norvegicus)
PDGF:phospho-PDGF receptor dimer:STAT [plasma membrane] (Rattus norvegicus)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Rattus norvegicus)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Rattus norvegicus)
active PDGF-AA dimer [extracellular region] (Rattus norvegicus)
Pdgfa [extracellular region] (Rattus norvegicus)
p130Cas and C3G bind PDGFR bound Crk (Rattus norvegicus)
PDGF:Phospho-PDGF receptor dimer:Crk [plasma membrane] (Rattus norvegicus)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Rattus norvegicus)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Rattus norvegicus)
active PDGF-AA dimer [extracellular region] (Rattus norvegicus)
Pdgfa [extracellular region] (Rattus norvegicus)
PDGF:Phospho-PDGF receptor dimer:Crk:p130Cas:C3G [plasma membrane] (Rattus norvegicus)
PDGF:Phospho-PDGF receptor dimer:Crk [plasma membrane] (Rattus norvegicus)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Rattus norvegicus)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Rattus norvegicus)
active PDGF-AA dimer [extracellular region] (Rattus norvegicus)
Pdgfa [extracellular region] (Rattus norvegicus)
PDGF binds to extracellular matrix proteins (Rattus norvegicus)
PDGF A and B chains with retention motif [extracellular region] (Rattus norvegicus)
Pdgfa [extracellular region] (Rattus norvegicus)
PDGF A and B chains:ECM complex [extracellular region] (Rattus norvegicus)
PDGF A and B chains with retention motif [extracellular region] (Rattus norvegicus)
Pdgfa [extracellular region] (Rattus norvegicus)
PDGF dimer binds two receptors simultaneously (Rattus norvegicus)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Rattus norvegicus)
active PDGF-AA dimer [extracellular region] (Rattus norvegicus)
Pdgfa [extracellular region] (Rattus norvegicus)
PDGF:PDGF receptor dimer [plasma membrane] (Rattus norvegicus)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Rattus norvegicus)
active PDGF-AA dimer [extracellular region] (Rattus norvegicus)
Pdgfa [extracellular region] (Rattus norvegicus)
PDGF-AA clevage by Furin (Rattus norvegicus)
active PDGF-AA dimer [extracellular region] (Rattus norvegicus)
Pdgfa [extracellular region] (Rattus norvegicus)
PDGFRs bind type I TKI (Rattus norvegicus)
PDGF alpha receptor: PDGF dimers [plasma membrane] (Rattus norvegicus)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Rattus norvegicus)
active PDGF-AA dimer [extracellular region] (Rattus norvegicus)
Pdgfa [extracellular region] (Rattus norvegicus)
PDGFR:type I PDGFR-binding TKIs [plasma membrane] (Rattus norvegicus)
PDGF alpha receptor: PDGF dimers [plasma membrane] (Rattus norvegicus)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Rattus norvegicus)
active PDGF-AA dimer [extracellular region] (Rattus norvegicus)
Pdgfa [extracellular region] (Rattus norvegicus)
External Reference Information
External Reference
UniProt:P28576
Gene Names
Pdgfa
Reference Genes
BioGPS Gene:25266 Pdgfa
ENSEMBL:ENSRNOG00000001312
ENSEMBL:ENSRNOG00000001312.9 Pdgfa
KEGG Gene (Rattus norvegicus):25266 Pdgfa
Monarch:25266 Pdgfa
NCBI Gene:25266 Pdgfa
UCSC:P28576 Pdgfa
Reference Transcript
RefSeq:NM_012801.1 Pdgfa
Other Identifiers
10757129
1370427_at
17672282
25266
5654135
5680595
5748124
5780200
5846961
5883641
6034910
6163572
6612334
A_42_P738559
A_44_P322910
A_64_P131409
D10106_s_at
GE19594
GE21880
GO:0001525
GO:0001666
GO:0001942
GO:0002053
GO:0005161
GO:0005518
GO:0005576
GO:0005615
GO:0005902
GO:0006629
GO:0007010
GO:0008083
GO:0008283
GO:0008284
GO:0008584
GO:0009410
GO:0009611
GO:0009887
GO:0009986
GO:0010033
GO:0010035
GO:0010512
GO:0010544
GO:0014910
GO:0016020
GO:0022414
GO:0023052
GO:0030031
GO:0030036
GO:0030335
GO:0031954
GO:0032355
GO:0032526
GO:0035793
GO:0036211
GO:0042060
GO:0042221
GO:0042803
GO:0043406
GO:0043410
GO:0043588
GO:0046982
GO:0048008
GO:0048018
GO:0048146
GO:0048286
GO:0048407
GO:0048565
GO:0048839
GO:0048856
GO:0048870
GO:0050730
GO:0050919
GO:0051781
GO:0051897
GO:0060348
GO:0060683
GO:0070374
GO:0071560
GO:0098772
GO:1990265
GO:1990401
Z14120cds_s_at
rc_AI013222_g_at
Participates
as a component of
PDGF AB heterodimer [extracellular region] (Rattus norvegicus)
active PDGF-AA dimer [extracellular region] (Rattus norvegicus)
as a member of
PDGF A and B chains with retention motif [extracellular region] (Rattus norvegicus)
Other forms of this molecule
Pdgfa [platelet alpha granule lumen]
Pdgfa [endoplasmic reticulum lumen]
Pdgfa [endoplasmic reticulum lumen]
Pdgfa [Golgi lumen]
Pdgfa [Golgi membrane]
Pdgfa [Golgi membrane]
Pdgfa [extracellular region]
Inferred From
Active platelet-derived growth factor A chain isoforms [extracellular region]
(Homo sapiens)
PDGFA-1 [extracellular region]
(Homo sapiens)
Cross References
RefSeq
NP_036933.1
Ensembl
ENSRNOT00000042117
,
ENSRNOP00000040116
,
ENSRNOG00000001312
PRO
P28576
RGD
3282
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