Reactome | Myc [nucleoplasm]

Myc [nucleoplasm]

Stable Identifier

R-RNO-188379

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

nucleoplasm

Synonyms

MYC, P09416

Locations in the PathwayBrowser

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Gene expression (Transcription) (Rattus norvegicus)

- RNA Polymerase II Transcription (Rattus norvegicus)
  - Generic Transcription Pathway (Rattus norvegicus)
    - Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors (Rattus norvegicus)
      - TFAP2 (AP-2) family regulates transcription of cell cycle factors (Rattus norvegicus)
        
        TFAP2C homodimer binds MYC and KDM5B (Rattus norvegicus)
        
        Myc [nucleoplasm] (Rattus norvegicus)
        
        TFAP2C homodimer:MYC:KDM5B [nucleoplasm] (Rattus norvegicus)
        
        Myc [nucleoplasm] (Rattus norvegicus)

Metabolism of proteins (Rattus norvegicus)

- Post-translational protein modification (Rattus norvegicus)
  - Deubiquitination (Rattus norvegicus)
    - Ub-specific processing proteases (Rattus norvegicus)
      - USP28 deubiquitinates CLSPN and MYC (Rattus norvegicus)
        
        USP28:CLSPN,MYC [nucleoplasm] (Rattus norvegicus)
        
        CLSPN, MYC [nucleoplasm] (Rattus norvegicus)
        
        Myc [nucleoplasm] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:P09416

Gene Names

Myc

Reference Genes

BioGPS Gene:24577 Myc

ENSEMBL:ENSRNOG00000004500

ENSEMBL:ENSRNOG00055023910

ENSEMBL:ENSRNOG00060003990

ENSEMBL:ENSRNOG00065004691

KEGG Gene (Rattus norvegicus):24577 Myc

Monarch:24577 Myc

NCBI Gene:24577 Myc

UCSC:P09416 Myc

Reference Transcript

RefSeq:NM_012603.2 Myc

Participates

as a member of

as an input of

TFAP2C homodimer binds MYC and KDM5B (Rattus norvegicus)

as a component of

Other forms of this molecule

Myc [nucleoplasm]

Inferred From

MYC [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_036735.2

PRO

P09416

RGD

3130

PDB

7LQT

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