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Ywhae [cytosol]
Stable Identifier
R-RNO-194368
Type
Protein [EntityWithAccessionedSequence]
Species
Rattus norvegicus
Compartment
cytosol
Synonyms
YWHAE, P62260
Locations in the PathwayBrowser
Expand all
Cell Cycle (Rattus norvegicus)
Cell Cycle Checkpoints (Rattus norvegicus)
G2/M Checkpoints (Rattus norvegicus)
G2/M DNA damage checkpoint (Rattus norvegicus)
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex (Rattus norvegicus)
Association of p-S216-CDC25C with 14-3-3 proteins (Rattus norvegicus)
14-3-3 dimer [cytosol] (Rattus norvegicus)
YWHAE dimer [cytosol] (Rattus norvegicus)
Ywhae [cytosol] (Rattus norvegicus)
p-S216-CDC25C:14-3-3 protein complex [cytosol] (Rattus norvegicus)
14-3-3 dimer [cytosol] (Rattus norvegicus)
YWHAE dimer [cytosol] (Rattus norvegicus)
Ywhae [cytosol] (Rattus norvegicus)
Cell Cycle, Mitotic (Rattus norvegicus)
M Phase (Rattus norvegicus)
Mitotic Prometaphase (Rattus norvegicus)
Recruitment of NuMA to mitotic centrosomes (Rattus norvegicus)
Association of NuMA with microtubules (Rattus norvegicus)
Mature centrosome enriched in gamma-TURC:p-T2055-NUMA1 homodimer [cytosol] (Rattus norvegicus)
Mature centrosomes enriched in gamma-TURC complexes [cytosol] (Rattus norvegicus)
centrosome [cytosol] (Rattus norvegicus)
Ywhae [cytosol] (Rattus norvegicus)
p-T2055-NUMA1 homodimer:Mature centrosome:nucleated microtubules [cytosol] (Rattus norvegicus)
Mature centrosome:nucleated microtubules [cytosol] (Rattus norvegicus)
Mature centrosomes enriched in gamma-TURC complexes [cytosol] (Rattus norvegicus)
centrosome [cytosol] (Rattus norvegicus)
Ywhae [cytosol] (Rattus norvegicus)
Translocation of NuMA to the centrosomes (Rattus norvegicus)
Mature centrosome enriched in gamma-TURC:p-T2055-NUMA1 homodimer [cytosol] (Rattus norvegicus)
Mature centrosomes enriched in gamma-TURC complexes [cytosol] (Rattus norvegicus)
centrosome [cytosol] (Rattus norvegicus)
Ywhae [cytosol] (Rattus norvegicus)
Mature centrosomes enriched in gamma-TURC complexes [cytosol] (Rattus norvegicus)
centrosome [cytosol] (Rattus norvegicus)
Ywhae [cytosol] (Rattus norvegicus)
Mitotic G2-G2/M phases (Rattus norvegicus)
G2/M Transition (Rattus norvegicus)
AURKA Activation by TPX2 (Rattus norvegicus)
TPX2 promotes AURKA autophosphorylation (Rattus norvegicus)
Centrosome:AURKA:TPX2:HMMR [cytosol] (Rattus norvegicus)
Centrosome:AURKA [cytosol] (Rattus norvegicus)
centrosome [cytosol] (Rattus norvegicus)
Ywhae [cytosol] (Rattus norvegicus)
Centrosome:p-T288-AURKA:TPX2:HMMR [cytosol] (Rattus norvegicus)
Centrosome:p-T288-AURKA [cytosol] (Rattus norvegicus)
centrosome [cytosol] (Rattus norvegicus)
Ywhae [cytosol] (Rattus norvegicus)
Centrosome maturation (Rattus norvegicus)
Loss of proteins required for interphase microtubule organization from the centrosome (Rattus norvegicus)
Loss of C-Nap-1 from centrosomes (Rattus norvegicus)
cNAP-1 depleted centrosome [cytosol] (Rattus norvegicus)
Ywhae [cytosol] (Rattus norvegicus)
centrosome [cytosol] (Rattus norvegicus)
Ywhae [cytosol] (Rattus norvegicus)
Loss of Nlp from mitotic centrosomes (Rattus norvegicus)
Dissociation of Phospho-Nlp from the centrosome (Rattus norvegicus)
Nlp-depleted centrosome [cytosol] (Rattus norvegicus)
Ywhae [cytosol] (Rattus norvegicus)
centrosome containing phosphorylated Nlp [cytosol] (Rattus norvegicus)
Ywhae [cytosol] (Rattus norvegicus)
Plk1-mediated phosphorylation of Nlp (Rattus norvegicus)
centrosome [cytosol] (Rattus norvegicus)
Ywhae [cytosol] (Rattus norvegicus)
centrosome containing phosphorylated Nlp [cytosol] (Rattus norvegicus)
Ywhae [cytosol] (Rattus norvegicus)
Recruitment of mitotic centrosome proteins and complexes (Rattus norvegicus)
Recruitment of CDK11p58 to the centrosomes (Rattus norvegicus)
Centrosomes containing recruited CDK11p58 [cytosol] (Rattus norvegicus)
centrosome [cytosol] (Rattus norvegicus)
Ywhae [cytosol] (Rattus norvegicus)
centrosome [cytosol] (Rattus norvegicus)
Ywhae [cytosol] (Rattus norvegicus)
Recruitment of Plk1 to centrosomes (Rattus norvegicus)
Centrosome associated Plk1 [cytosol] (Rattus norvegicus)
centrosome [cytosol] (Rattus norvegicus)
Ywhae [cytosol] (Rattus norvegicus)
centrosome [cytosol] (Rattus norvegicus)
Ywhae [cytosol] (Rattus norvegicus)
Recruitment of additional gamma tubulin/ gamma TuRC to the centrosome (Rattus norvegicus)
Mature centrosomes enriched in gamma-TURC complexes [cytosol] (Rattus norvegicus)
centrosome [cytosol] (Rattus norvegicus)
Ywhae [cytosol] (Rattus norvegicus)
centrosome [cytosol] (Rattus norvegicus)
Ywhae [cytosol] (Rattus norvegicus)
Regulation of PLK1 Activity at G2/M Transition (Rattus norvegicus)
AJUBA binds centrosome-associated AURKA (Rattus norvegicus)
Centrosome:AURKA [cytosol] (Rattus norvegicus)
centrosome [cytosol] (Rattus norvegicus)
Ywhae [cytosol] (Rattus norvegicus)
Centrosome:AURKA:AJUBA [cytosol] (Rattus norvegicus)
Centrosome:AURKA [cytosol] (Rattus norvegicus)
centrosome [cytosol] (Rattus norvegicus)
Ywhae [cytosol] (Rattus norvegicus)
AJUBA facilitates AURKA autophosphorylation (Rattus norvegicus)
Centrosome:AURKA:AJUBA [cytosol] (Rattus norvegicus)
Centrosome:AURKA [cytosol] (Rattus norvegicus)
centrosome [cytosol] (Rattus norvegicus)
Ywhae [cytosol] (Rattus norvegicus)
Centrosome:p-T288-AURKA [cytosol] (Rattus norvegicus)
centrosome [cytosol] (Rattus norvegicus)
Ywhae [cytosol] (Rattus norvegicus)
AURKA phosphorylates PLK1 (Rattus norvegicus)
Centrosome:p-T288-AURKA [cytosol] (Rattus norvegicus)
centrosome [cytosol] (Rattus norvegicus)
Ywhae [cytosol] (Rattus norvegicus)
Centrosome:p-T288-AURKA:p-S252-BORA:PLK1 [cytosol] (Rattus norvegicus)
Centrosome:p-T288-AURKA [cytosol] (Rattus norvegicus)
centrosome [cytosol] (Rattus norvegicus)
Ywhae [cytosol] (Rattus norvegicus)
BORA binds PLK1 and AURKA (Rattus norvegicus)
Centrosome:p-T288-AURKA [cytosol] (Rattus norvegicus)
centrosome [cytosol] (Rattus norvegicus)
Ywhae [cytosol] (Rattus norvegicus)
Centrosome:p-T288-AURKA:p-S252-BORA:PLK1 [cytosol] (Rattus norvegicus)
Centrosome:p-T288-AURKA [cytosol] (Rattus norvegicus)
centrosome [cytosol] (Rattus norvegicus)
Ywhae [cytosol] (Rattus norvegicus)
Cellular responses to stimuli (Rattus norvegicus)
Cellular responses to stress (Rattus norvegicus)
Cellular response to heat stress (Rattus norvegicus)
HSF1 activation (Rattus norvegicus)
HSF1 trimer translocates to the nucleus (Rattus norvegicus)
YWHAE dimer [cytosol] (Rattus norvegicus)
Ywhae [cytosol] (Rattus norvegicus)
Regulation of HSF1-mediated heat shock response (Rattus norvegicus)
p-S303,307-HSF1 binds YWHAE (14-3-3) (Rattus norvegicus)
YWHAE dimer [cytosol] (Rattus norvegicus)
Ywhae [cytosol] (Rattus norvegicus)
p-S303,307-HSF1:YWHAE [cytosol] (Rattus norvegicus)
YWHAE dimer [cytosol] (Rattus norvegicus)
Ywhae [cytosol] (Rattus norvegicus)
Gene expression (Transcription) (Rattus norvegicus)
RNA Polymerase II Transcription (Rattus norvegicus)
Generic Transcription Pathway (Rattus norvegicus)
Transcriptional Regulation by TP53 (Rattus norvegicus)
TP53 Regulates Metabolic Genes (Rattus norvegicus)
DDIT4 binds 14-3-3 dimer (Rattus norvegicus)
14-3-3 dimer [cytosol] (Rattus norvegicus)
YWHAE dimer [cytosol] (Rattus norvegicus)
Ywhae [cytosol] (Rattus norvegicus)
DDIT4:14-3-3 dimer [cytosol] (Rattus norvegicus)
14-3-3 dimer [cytosol] (Rattus norvegicus)
YWHAE dimer [cytosol] (Rattus norvegicus)
Ywhae [cytosol] (Rattus norvegicus)
p-S939,T1462-TSC2 binding to 14-3-3 dimer is negatively regulated by DDIT4 (Rattus norvegicus)
14-3-3 dimer [cytosol] (Rattus norvegicus)
YWHAE dimer [cytosol] (Rattus norvegicus)
Ywhae [cytosol] (Rattus norvegicus)
DDIT4:14-3-3 dimer [cytosol] (Rattus norvegicus)
14-3-3 dimer [cytosol] (Rattus norvegicus)
YWHAE dimer [cytosol] (Rattus norvegicus)
Ywhae [cytosol] (Rattus norvegicus)
p-S939,T1462-TSC2:14-3-3 dimer [cytosol] (Rattus norvegicus)
14-3-3 dimer [cytosol] (Rattus norvegicus)
YWHAE dimer [cytosol] (Rattus norvegicus)
Ywhae [cytosol] (Rattus norvegicus)
Organelle biogenesis and maintenance (Rattus norvegicus)
Cilium Assembly (Rattus norvegicus)
Anchoring of the basal body to the plasma membrane (Rattus norvegicus)
C2CD3 and OFD1 recruit 5 distal appendage proteins to the centriole (Rattus norvegicus)
Centrosome:C2CD3:distal appendage proteins [cytosol] (Rattus norvegicus)
mother centriole:C2CD3 [cytosol] (Rattus norvegicus)
mother centriole [cytosol] (Rattus norvegicus)
Ywhae [cytosol] (Rattus norvegicus)
mother centriole:C2CD3 [cytosol] (Rattus norvegicus)
mother centriole [cytosol] (Rattus norvegicus)
Ywhae [cytosol] (Rattus norvegicus)
C2CD3 binds the mother centriole (Rattus norvegicus)
mother centriole [cytosol] (Rattus norvegicus)
Ywhae [cytosol] (Rattus norvegicus)
mother centriole:C2CD3 [cytosol] (Rattus norvegicus)
mother centriole [cytosol] (Rattus norvegicus)
Ywhae [cytosol] (Rattus norvegicus)
CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body (Rattus norvegicus)
basal body:transition zone proteins [cytosol] (Rattus norvegicus)
basal body [cytosol] (Rattus norvegicus)
centrosome without CEP164, CCP110 or CEP97 [cytosol] (Rattus norvegicus)
Ywhae [cytosol] (Rattus norvegicus)
basal body:transition zone proteins:RAB3IP:RAB11A:GTP:Golgi-derived vesicle [cytosol] (Rattus norvegicus)
basal body:transition zone proteins [cytosol] (Rattus norvegicus)
basal body [cytosol] (Rattus norvegicus)
centrosome without CEP164, CCP110 or CEP97 [cytosol] (Rattus norvegicus)
Ywhae [cytosol] (Rattus norvegicus)
CP110 and CEP97 dissociate from the centriole (Rattus norvegicus)
basal body [cytosol] (Rattus norvegicus)
centrosome without CEP164, CCP110 or CEP97 [cytosol] (Rattus norvegicus)
Ywhae [cytosol] (Rattus norvegicus)
centrosome:C2CD2:distal appendage proteins:TTBK2:MARK4 [cytosol] (Rattus norvegicus)
Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Rattus norvegicus)
Centrosome:C2CD3:distal appendage proteins [cytosol] (Rattus norvegicus)
mother centriole:C2CD3 [cytosol] (Rattus norvegicus)
mother centriole [cytosol] (Rattus norvegicus)
Ywhae [cytosol] (Rattus norvegicus)
MARK4 binds ODF2 in the centriole (Rattus norvegicus)
Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Rattus norvegicus)
Centrosome:C2CD3:distal appendage proteins [cytosol] (Rattus norvegicus)
mother centriole:C2CD3 [cytosol] (Rattus norvegicus)
mother centriole [cytosol] (Rattus norvegicus)
Ywhae [cytosol] (Rattus norvegicus)
centrosome:C2CD2:distal appendage proteins:TTBK2:MARK4 [cytosol] (Rattus norvegicus)
Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Rattus norvegicus)
Centrosome:C2CD3:distal appendage proteins [cytosol] (Rattus norvegicus)
mother centriole:C2CD3 [cytosol] (Rattus norvegicus)
mother centriole [cytosol] (Rattus norvegicus)
Ywhae [cytosol] (Rattus norvegicus)
RAB3IP stimulates nucleotide exchange on RAB8A (Rattus norvegicus)
basal body:transition zone proteins:RAB3IP:RAB11A:GTP:Golgi-derived vesicle [cytosol] (Rattus norvegicus)
basal body:transition zone proteins [cytosol] (Rattus norvegicus)
basal body [cytosol] (Rattus norvegicus)
centrosome without CEP164, CCP110 or CEP97 [cytosol] (Rattus norvegicus)
Ywhae [cytosol] (Rattus norvegicus)
Recruitment of transition zone proteins (Rattus norvegicus)
basal body [cytosol] (Rattus norvegicus)
centrosome without CEP164, CCP110 or CEP97 [cytosol] (Rattus norvegicus)
Ywhae [cytosol] (Rattus norvegicus)
basal body:transition zone proteins [cytosol] (Rattus norvegicus)
basal body [cytosol] (Rattus norvegicus)
centrosome without CEP164, CCP110 or CEP97 [cytosol] (Rattus norvegicus)
Ywhae [cytosol] (Rattus norvegicus)
The distal appendage proteins recruit TTBK2 (Rattus norvegicus)
Centrosome:C2CD3:distal appendage proteins [cytosol] (Rattus norvegicus)
mother centriole:C2CD3 [cytosol] (Rattus norvegicus)
mother centriole [cytosol] (Rattus norvegicus)
Ywhae [cytosol] (Rattus norvegicus)
Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Rattus norvegicus)
Centrosome:C2CD3:distal appendage proteins [cytosol] (Rattus norvegicus)
mother centriole:C2CD3 [cytosol] (Rattus norvegicus)
mother centriole [cytosol] (Rattus norvegicus)
Ywhae [cytosol] (Rattus norvegicus)
Programmed Cell Death (Rattus norvegicus)
Apoptosis (Rattus norvegicus)
Intrinsic Pathway for Apoptosis (Rattus norvegicus)
Activation of BH3-only proteins (Rattus norvegicus)
Activation of BAD and translocation to mitochondria (Rattus norvegicus)
Activation of BAD by calcineurin (Rattus norvegicus)
14-3-3 dimer [cytosol] (Rattus norvegicus)
YWHAE dimer [cytosol] (Rattus norvegicus)
Ywhae [cytosol] (Rattus norvegicus)
14-3-3 proteins:p-S99-BAD complex [cytosol] (Rattus norvegicus)
14-3-3 dimer [cytosol] (Rattus norvegicus)
YWHAE dimer [cytosol] (Rattus norvegicus)
Ywhae [cytosol] (Rattus norvegicus)
Sequestration of BAD protein by 14-3-3 (Rattus norvegicus)
14-3-3 dimer [cytosol] (Rattus norvegicus)
YWHAE dimer [cytosol] (Rattus norvegicus)
Ywhae [cytosol] (Rattus norvegicus)
14-3-3 proteins:p-S99-BAD complex [cytosol] (Rattus norvegicus)
14-3-3 dimer [cytosol] (Rattus norvegicus)
YWHAE dimer [cytosol] (Rattus norvegicus)
Ywhae [cytosol] (Rattus norvegicus)
Signal Transduction (Rattus norvegicus)
Death Receptor Signaling (Rattus norvegicus)
p75 NTR receptor-mediated signalling (Rattus norvegicus)
Cell death signalling via NRAGE, NRIF and NADE (Rattus norvegicus)
NADE modulates death signalling (Rattus norvegicus)
14-3-3epsilon attentuates NADE-related apoptosis (Rattus norvegicus)
NGF ligand:p75NTR:NADE:14-3-3epsilon [plasma membrane] (Rattus norvegicus)
YWHAE dimer [cytosol] (Rattus norvegicus)
Ywhae [cytosol] (Rattus norvegicus)
YWHAE dimer [cytosol] (Rattus norvegicus)
Ywhae [cytosol] (Rattus norvegicus)
Signaling by Hippo (Rattus norvegicus)
YWHAE (14-3-3 epsilon) dimer binds phosphorylated WWTR1 (TAZ) (Rattus norvegicus)
YWHAE dimer [cytosol] (Rattus norvegicus)
Ywhae [cytosol] (Rattus norvegicus)
p-WWTR1:YWHAE [cytosol] (Rattus norvegicus)
YWHAE dimer [cytosol] (Rattus norvegicus)
Ywhae [cytosol] (Rattus norvegicus)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Rattus norvegicus)
Signaling by Rho GTPases (Rattus norvegicus)
RHO GTPase Effectors (Rattus norvegicus)
RHO GTPases activate PKNs (Rattus norvegicus)
Association of p-S216-CDC25C with 14-3-3 proteins (Rattus norvegicus)
14-3-3 dimer [cytosol] (Rattus norvegicus)
YWHAE dimer [cytosol] (Rattus norvegicus)
Ywhae [cytosol] (Rattus norvegicus)
p-S216-CDC25C:14-3-3 protein complex [cytosol] (Rattus norvegicus)
14-3-3 dimer [cytosol] (Rattus norvegicus)
YWHAE dimer [cytosol] (Rattus norvegicus)
Ywhae [cytosol] (Rattus norvegicus)
Vesicle-mediated transport (Rattus norvegicus)
Membrane Trafficking (Rattus norvegicus)
Rab regulation of trafficking (Rattus norvegicus)
RAB GEFs exchange GTP for GDP on RABs (Rattus norvegicus)
DENND1s exchange GTP for GDP on RAB35 (Rattus norvegicus)
RAB35 GEFs [cytosol] (Rattus norvegicus)
p-2S-DENND1A,B:YWHAE dimer [cytosol] (Rattus norvegicus)
YWHAE dimer [cytosol] (Rattus norvegicus)
Ywhae [cytosol] (Rattus norvegicus)
YWHAE dimer binds phosphorylated DENND1 proteins (Rattus norvegicus)
YWHAE dimer [cytosol] (Rattus norvegicus)
Ywhae [cytosol] (Rattus norvegicus)
p-2S-DENND1A,B:YWHAE dimer [cytosol] (Rattus norvegicus)
YWHAE dimer [cytosol] (Rattus norvegicus)
Ywhae [cytosol] (Rattus norvegicus)
External Reference Information
External Reference
UniProt:P62260
Gene Names
Ywhae
Reference Genes
BioGPS Gene:29753 Ywhae
ENSEMBL:ENSRNOG00000005290
ENSEMBL:ENSRNOG00000005290.6 Ywhae
KEGG Gene (Rattus norvegicus):29753 Ywhae
Monarch:29753 Ywhae
NCBI Gene:29753 Ywhae
Reference Transcript
RefSeq:NM_031603.1 Ywhae
Other Identifiers
10736042
1398851_at
17648683
29753
5931948
5943346
6018197
6183473
6186777
6308395
6362930
6586624
6734517
A_44_P135168
A_44_P135170
D30739_s_at
GE20965
GE21848
ILMN_1352855
PH_rn_0004175
rc_AI176615_s_at
Participates
as a component of
centrosome without CEP164, CCP110 or CEP97 [cytosol] (Rattus norvegicus)
mother centriole [cytosol] (Rattus norvegicus)
Nlp-depleted centrosome [cytosol] (Rattus norvegicus)
centrosome containing phosphorylated Nlp [cytosol] (Rattus norvegicus)
cNAP-1 depleted centrosome [cytosol] (Rattus norvegicus)
YWHAE dimer [cytosol] (Rattus norvegicus)
centrosome [cytosol] (Rattus norvegicus)
Inferred From
YWHAE [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_113791.1
Ensembl
ENSRNOG00000005290
,
ENSRNOP00000007100
,
ENSRNOT00000007100
PRO
P62260
RGD
62000
© 2024
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