Reactome | Elmo1 [cytosol]

Elmo1 [cytosol]

Stable Identifier

R-RNO-200932

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

cytosol

Synonyms

ELMO1, D3ZY46

Locations in the PathwayBrowser

Expand all

Immune System (Rattus norvegicus)

- Innate Immune System (Rattus norvegicus)
  - Fcgamma receptor (FCGR) dependent phagocytosis (Rattus norvegicus)
    - Regulation of actin dynamics for phagocytic cup formation (Rattus norvegicus)
      - Activation of RAC1 by CRKII:DOCK180:ELMO (Rattus norvegicus)
        
        CRKII:DOCK180:ELMO complex recruited to phagocytic cup [plasma membrane] (Rattus norvegicus)
        
        CRK:DOCK180:ELMO1,ELMO2 [cytosol] (Rattus norvegicus)
        
        ELMO1,ELMO2 [cytosol] (Rattus norvegicus)
        
        Elmo1 [cytosol] (Rattus norvegicus)

Signal Transduction (Rattus norvegicus)

- Signaling by Non-Receptor Tyrosine Kinases (Rattus norvegicus)
  - Signaling by PTK6 (Rattus norvegicus)
    - PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases (Rattus norvegicus)
      - Activation of RAC1 by the PXN:CRK complex (Rattus norvegicus)
        
        p-Y31,Y118-PXN:CRK:DOCK180:ELMO1,ELMO2 [cytosol] (Rattus norvegicus)
        
        CRK:DOCK180:ELMO1,ELMO2 [cytosol] (Rattus norvegicus)
        
        ELMO1,ELMO2 [cytosol] (Rattus norvegicus)
        
        Elmo1 [cytosol] (Rattus norvegicus)
- Signaling by Receptor Tyrosine Kinases (Rattus norvegicus)
  - Signaling by VEGF (Rattus norvegicus)
    - VEGFA-VEGFR2 Pathway (Rattus norvegicus)
      - DOCK180:ELMO exchanges GTP for GDP, activating RAC1 (Rattus norvegicus)
        
        CRK:DOCK180:ELMO1,ELMO2:VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-12Y-BCAR1,VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-Y31,Y118-PXN [plasma membrane] (Rattus norvegicus)
        
        CRK:DOCK180:ELMO1,ELMO2 [cytosol] (Rattus norvegicus)
        
        ELMO1,ELMO2 [cytosol] (Rattus norvegicus)
        
        Elmo1 [cytosol] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:D3ZY46

Gene Names

Elmo1

Reference Genes

ENSEMBL:ENSRNOG00000059705

ENSEMBL:ENSRNOG00000059705.2 Elmo1

UCSC:D3ZY46 Elmo1

Other Identifiers

10798583

1379396_at

17719631

361251

5622309

5655252

5675979

5729400

5750238

5756492

5818237

5917837

5963359

5965588

6017177

6057417

6071640

6100529

6218515

6266825

6292465

6442976

6450473

6473972

6488298

6493174

6628130

6705758

6733697

A_43_P13491

A_44_P515792

A_44_P592344

GE1254545

GO:0005085

GO:0005737

GO:0005886

GO:0006909

GO:0006911

GO:0007010

GO:0016192

GO:0016601

GO:0017124

GO:0023052

GO:0030029

GO:0030036

GO:0032045

GO:0048870

GO:0061024

GO:0098772

ILMN_1353691

PH_rn_0011015

rc_AI007626_at

Participates

as a member of

ELMO1,ELMO2 [cytosol] (Rattus norvegicus)

Inferred From

ELMO1 [cytosol] (Homo sapiens)

Cross References

Ensembl

ENSRNOP00000073757, ENSRNOG00000059705, ENSRNOT00000090663

RGD

1308182

Cite Us!