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Tcf7l2 [nucleoplasm]
Stable Identifier
R-RNO-201923
Type
Protein [EntityWithAccessionedSequence]
Species
Rattus norvegicus
Compartment
nucleoplasm
Synonyms
TCF7L2, A0A8I6A9A2
Locations in the PathwayBrowser
Expand all
Developmental Biology (Rattus norvegicus)
MITF-M-regulated melanocyte development (Rattus norvegicus)
MITF-M-dependent gene expression (Rattus norvegicus)
Regulation of MITF-M-dependent genes involved in cell cycle and proliferation (Rattus norvegicus)
HINT1, HDAC1, and SIN3A bind CTNNB1 at the CCND1 promoter (Rattus norvegicus)
HINT1:HDAC1:SIN3A:TCF/LEF:CTNNB1:CCND1 gene [nucleoplasm] (Rattus norvegicus)
TCF/LEF:CTNNB1:CCND1 gene [nucleoplasm] (Rattus norvegicus)
TCF/LEF:CTNNB1 [nucleoplasm] (Rattus norvegicus)
TCF/LEF [nucleoplasm] (Rattus norvegicus)
Tcf7l2 [nucleoplasm] (Rattus norvegicus)
TCF/LEF:CTNNB1:CCND1 gene [nucleoplasm] (Rattus norvegicus)
TCF/LEF:CTNNB1 [nucleoplasm] (Rattus norvegicus)
TCF/LEF [nucleoplasm] (Rattus norvegicus)
Tcf7l2 [nucleoplasm] (Rattus norvegicus)
Gene expression (Transcription) (Rattus norvegicus)
RNA Polymerase II Transcription (Rattus norvegicus)
Generic Transcription Pathway (Rattus norvegicus)
Transcriptional regulation by RUNX3 (Rattus norvegicus)
RUNX3 regulates WNT signaling (Rattus norvegicus)
RUNX3 binds CTNNB1:TCF7L2,(LEF1,TCF7L1,TCF7) (Rattus norvegicus)
CTNNB1:TCF7L2,(LEF1,TCF7L1,TCF7) [nucleoplasm] (Rattus norvegicus)
TCF7L2,(LEF1,TCF7L1,TCF7) [nucleoplasm] (Rattus norvegicus)
Tcf7l2 [nucleoplasm] (Rattus norvegicus)
RUNX3:CTNNB1:TCF7L2,(LEF1,TCF7L1,TCF7) [nucleoplasm] (Rattus norvegicus)
CTNNB1:TCF7L2,(LEF1,TCF7L1,TCF7) [nucleoplasm] (Rattus norvegicus)
TCF7L2,(LEF1,TCF7L1,TCF7) [nucleoplasm] (Rattus norvegicus)
Tcf7l2 [nucleoplasm] (Rattus norvegicus)
Signal Transduction (Rattus norvegicus)
Signaling by WNT (Rattus norvegicus)
Beta-catenin independent WNT signaling (Rattus norvegicus)
Ca2+ pathway (Rattus norvegicus)
NLK phosphorylates TCF/LEF (Rattus norvegicus)
TCF/LEF:CTNNB1 [nucleoplasm] (Rattus norvegicus)
TCF7L2,LEF1 [nucleoplasm] (Rattus norvegicus)
Tcf7l2 [nucleoplasm] (Rattus norvegicus)
Degradation of beta-catenin by the destruction complex (Rattus norvegicus)
Repression of WNT target genes (Rattus norvegicus)
TCF7L2/TCF7L1 bind CTBP1 to repress WNT target genes (Rattus norvegicus)
TCF7L2/TCF7L1 [nucleoplasm] (Rattus norvegicus)
Tcf7l2 [nucleoplasm] (Rattus norvegicus)
TCF7L2/TCF7L1:CTBPs [nucleoplasm] (Rattus norvegicus)
TCF7L2/TCF7L1 [nucleoplasm] (Rattus norvegicus)
Tcf7l2 [nucleoplasm] (Rattus norvegicus)
TLE tetramers bind TCF/LEF at WNT promoters (Rattus norvegicus)
'canonical' WNT target gene:TCF/LEF:TLE tetramer [nucleoplasm] (Rattus norvegicus)
'canonical' WNT target genes:TCF/LEF [nucleoplasm] (Rattus norvegicus)
TCF/LEF [nucleoplasm] (Rattus norvegicus)
Tcf7l2 [nucleoplasm] (Rattus norvegicus)
'canonical' WNT target genes:TCF/LEF [nucleoplasm] (Rattus norvegicus)
TCF/LEF [nucleoplasm] (Rattus norvegicus)
Tcf7l2 [nucleoplasm] (Rattus norvegicus)
TCF dependent signaling in response to WNT (Rattus norvegicus)
Deactivation of the beta-catenin transactivating complex (Rattus norvegicus)
TCF:Beta-catenin binds SOX proteins (Rattus norvegicus)
TCF/LEF:CTNNB1 [nucleoplasm] (Rattus norvegicus)
TCF/LEF [nucleoplasm] (Rattus norvegicus)
Tcf7l2 [nucleoplasm] (Rattus norvegicus)
TCF/LEF:CTNNB1:SOX4,SOX13,SOX17 [nucleoplasm] (Rattus norvegicus)
TCF/LEF:CTNNB1 [nucleoplasm] (Rattus norvegicus)
TCF/LEF [nucleoplasm] (Rattus norvegicus)
Tcf7l2 [nucleoplasm] (Rattus norvegicus)
beta-catenin is replaced by repression complexes at the promoter (Rattus norvegicus)
TCF/LEF:CTNNB1:APC:CTBP:BTRC [nucleoplasm] (Rattus norvegicus)
TCF/LEF [nucleoplasm] (Rattus norvegicus)
Tcf7l2 [nucleoplasm] (Rattus norvegicus)
TCF/LEF:TLE:HDAC1 [nucleoplasm] (Rattus norvegicus)
TCF/LEF [nucleoplasm] (Rattus norvegicus)
Tcf7l2 [nucleoplasm] (Rattus norvegicus)
Formation of the beta-catenin:TCF transactivating complex (Rattus norvegicus)
Beta-catenin displaces TLE:HDAC1 from TCF/LEF (Rattus norvegicus)
TCF/LEF:CTNNB1 [nucleoplasm] (Rattus norvegicus)
TCF/LEF [nucleoplasm] (Rattus norvegicus)
Tcf7l2 [nucleoplasm] (Rattus norvegicus)
TCF/LEF:TLE:HDAC1 [nucleoplasm] (Rattus norvegicus)
TCF/LEF [nucleoplasm] (Rattus norvegicus)
Tcf7l2 [nucleoplasm] (Rattus norvegicus)
Beta-catenin recruits CBP/p300 (Rattus norvegicus)
TCF/LEF:CTNNB1 [nucleoplasm] (Rattus norvegicus)
TCF/LEF [nucleoplasm] (Rattus norvegicus)
Tcf7l2 [nucleoplasm] (Rattus norvegicus)
TCF/LEF:CTNNB1:CBP/p300 [nucleoplasm] (Rattus norvegicus)
TCF/LEF:CTNNB1 [nucleoplasm] (Rattus norvegicus)
TCF/LEF [nucleoplasm] (Rattus norvegicus)
Tcf7l2 [nucleoplasm] (Rattus norvegicus)
Beta-catenin recruits CDC73 and LEO1 (Rattus norvegicus)
TCF/LEF:CTNNB1 [nucleoplasm] (Rattus norvegicus)
TCF/LEF [nucleoplasm] (Rattus norvegicus)
Tcf7l2 [nucleoplasm] (Rattus norvegicus)
TCF/LEF:CTNNB1:PAF1-like complex [nucleoplasm] (Rattus norvegicus)
TCF/LEF:CTNNB1 [nucleoplasm] (Rattus norvegicus)
TCF/LEF [nucleoplasm] (Rattus norvegicus)
Tcf7l2 [nucleoplasm] (Rattus norvegicus)
Beta-catenin recruits SMARCA4 (Rattus norvegicus)
TCF/LEF:CTNNB1 [nucleoplasm] (Rattus norvegicus)
TCF/LEF [nucleoplasm] (Rattus norvegicus)
Tcf7l2 [nucleoplasm] (Rattus norvegicus)
TCF/LEF:CTNNB1:SMARCA4:TERT [nucleoplasm] (Rattus norvegicus)
TCF/LEF:CTNNB1 [nucleoplasm] (Rattus norvegicus)
TCF/LEF [nucleoplasm] (Rattus norvegicus)
Tcf7l2 [nucleoplasm] (Rattus norvegicus)
Beta-catenin recruits TRRAP/KAT5 HAT components (Rattus norvegicus)
TCF/LEF:CTNNB1 [nucleoplasm] (Rattus norvegicus)
TCF/LEF [nucleoplasm] (Rattus norvegicus)
Tcf7l2 [nucleoplasm] (Rattus norvegicus)
TCF/LEF:CTNNB1:RUVBL1:TRRAP:KAT5 [nucleoplasm] (Rattus norvegicus)
TCF/LEF:CTNNB1 [nucleoplasm] (Rattus norvegicus)
TCF/LEF [nucleoplasm] (Rattus norvegicus)
Tcf7l2 [nucleoplasm] (Rattus norvegicus)
Beta-catenin:TCF associates with BCL9 and PYGO (Rattus norvegicus)
TCF/LEF:CTNNB1 [nucleoplasm] (Rattus norvegicus)
TCF/LEF [nucleoplasm] (Rattus norvegicus)
Tcf7l2 [nucleoplasm] (Rattus norvegicus)
TCF/LEF:CTNNB1:BCL9:PYGO [nucleoplasm] (Rattus norvegicus)
TCF/LEF [nucleoplasm] (Rattus norvegicus)
Tcf7l2 [nucleoplasm] (Rattus norvegicus)
External Reference Information
External Reference
UniProt:A0A8I6A9A2
Gene Names
Tcf7l2
Reference Genes
ENSEMBL:ENSRNOG00000013993
ENSEMBL:ENSRNOG00000049232
ENSEMBL:ENSRNOG00000049232.3 Tcf7l2
Other Identifiers
10716189
1377156_at
1378048_at
1394497_at
17626561
5676886
5700331
5795631
5885783
5928907
5949813
6016889
6028441
6088569
6149014
6228352
6289013
6364269
6367808
6517072
6531827
6653190
6705580
6721919
679869
A_44_P1055506
A_44_P137846
A_44_P261779
A_64_P040190
A_64_P099307
GE1149694
GE17917
GE19116
GO:0000122
GO:0000785
GO:0000976
GO:0000978
GO:0001568
GO:0003677
GO:0003700
GO:0005634
GO:0005654
GO:0005694
GO:0006351
GO:0006355
GO:0006357
GO:0006790
GO:0008013
GO:0010718
GO:0010909
GO:0016055
GO:0016922
GO:0019901
GO:0023052
GO:0030154
GO:0032024
GO:0032350
GO:0032993
GO:0042593
GO:0043226
GO:0043565
GO:0043570
GO:0045295
GO:0045444
GO:0045892
GO:0045944
GO:0048625
GO:0048660
GO:0048856
GO:0050679
GO:0051897
GO:0060070
GO:0061629
GO:0070016
GO:0070369
GO:0090090
GO:0140110
GO:1900182
GO:1901135
ILMN_1348896
PH_rn_0016498
PH_rn_0022623
rc_AI059480_at
Participates
as a member of
TCF7L2/TCF7L1 [nucleoplasm] (Rattus norvegicus)
TCF/LEF [nucleoplasm] (Rattus norvegicus)
TCF/LEF [nucleoplasm] (Rattus norvegicus)
TCF7L2,(LEF1,TCF7L1,TCF7) [nucleoplasm] (Rattus norvegicus)
TCF7L2,LEF1 [nucleoplasm] (Rattus norvegicus)
as a candidate of
TCF7L1/TCF7L2/LEF1 [nucleoplasm] (Rattus norvegicus)
Other forms of this molecule
phospho-Tcf7l2 [nucleoplasm]
Inferred From
TCF7L2 [nucleoplasm]
(Homo sapiens)
Cross References
Ensembl
ENSRNOP00000087697
,
ENSRNOT00000100362
,
ENSRNOG00000049232
RGD
1583621
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