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About
What is Reactome ?
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UBE2N:UBE2V1 [cytosol]
Stable Identifier
R-RNO-202463
Type
Complex
Species
Rattus norvegicus
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Autophagy (Rattus norvegicus)
Macroautophagy (Rattus norvegicus)
Selective autophagy (Rattus norvegicus)
Aggrephagy (Rattus norvegicus)
Misfolded proteins bind PRKN:UBE2N:UBE2V1:Ub (Rattus norvegicus)
Misfolded proteins:PRKN:UBE2N:UBE2V1:Ub [cytosol] (Rattus norvegicus)
Ub:UBE2N:UBE2V1:PRKN [cytosol] (Rattus norvegicus)
Ub:UBE2N:UBE2V1 [cytosol] (Rattus norvegicus)
UBE2N:UBE2V1 [cytosol] (Rattus norvegicus)
Ub:UBE2N:UBE2V1:PRKN [cytosol] (Rattus norvegicus)
Ub:UBE2N:UBE2V1 [cytosol] (Rattus norvegicus)
UBE2N:UBE2V1 [cytosol] (Rattus norvegicus)
Parkin transfers Ub to misfolded proteins (Rattus norvegicus)
Misfolded proteins:PRKN:UBE2N:UBE2V1:Ub [cytosol] (Rattus norvegicus)
Ub:UBE2N:UBE2V1:PRKN [cytosol] (Rattus norvegicus)
Ub:UBE2N:UBE2V1 [cytosol] (Rattus norvegicus)
UBE2N:UBE2V1 [cytosol] (Rattus norvegicus)
Ub:Misfolded proteins:PRKN:UBE2N:UBE2V1 [cytosol] (Rattus norvegicus)
UBE2N:UBE2V1:PRKN [cytosol] (Rattus norvegicus)
UBE2N:UBE2V1 [cytosol] (Rattus norvegicus)
Ub:misfolded proteins polymerize to PolyUb:misfolded proteins (Rattus norvegicus)
PolyUb:Misfolded proteins:PRKN:UBE2N:UBE2V1 [cytosol] (Rattus norvegicus)
UBE2N:UBE2V1:PRKN [cytosol] (Rattus norvegicus)
UBE2N:UBE2V1 [cytosol] (Rattus norvegicus)
Ub:Misfolded proteins:PRKN:UBE2N:UBE2V1 [cytosol] (Rattus norvegicus)
UBE2N:UBE2V1:PRKN [cytosol] (Rattus norvegicus)
UBE2N:UBE2V1 [cytosol] (Rattus norvegicus)
Immune System (Rattus norvegicus)
Cytokine Signaling in Immune system (Rattus norvegicus)
Signaling by Interleukins (Rattus norvegicus)
Interleukin-1 family signaling (Rattus norvegicus)
Interleukin-1 signaling (Rattus norvegicus)
Pellino ubiquitinates IRAK1 (Rattus norvegicus)
K63polyUb-hp-IRAK1:p-Pellino-1,2,(3):UBE2N:UBE2V1 [cytosol] (Rattus norvegicus)
UBE2N:UBE2V1 [cytosol] (Rattus norvegicus)
TAK1 is activated within the TAK1 complex (Rattus norvegicus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Rattus norvegicus)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Rattus norvegicus)
UBE2N:UBE2V1 [cytosol] (Rattus norvegicus)
TRAF6 is K63 poly-ubiquitinated (Rattus norvegicus)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Rattus norvegicus)
UBE2N:UBE2V1 [cytosol] (Rattus norvegicus)
Interleukin-17 signaling (Rattus norvegicus)
MAP kinase activation (Rattus norvegicus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Rattus norvegicus)
Activated TAK1 phosphorylates MKK4/MKK7 (Rattus norvegicus)
Activated TAK complexes [cytosol] (Rattus norvegicus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Rattus norvegicus)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Rattus norvegicus)
UBE2N:UBE2V1 [cytosol] (Rattus norvegicus)
activated TAK1 mediates p38 MAPK activation (Rattus norvegicus)
activated human TAK1 phosphorylates MKK3/MKK6 (Rattus norvegicus)
Activated TAK complexes [cytosol] (Rattus norvegicus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Rattus norvegicus)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Rattus norvegicus)
UBE2N:UBE2V1 [cytosol] (Rattus norvegicus)
Innate Immune System (Rattus norvegicus)
Toll-like Receptor Cascades (Rattus norvegicus)
Toll Like Receptor 10 (TLR10) Cascade (Rattus norvegicus)
MyD88 cascade initiated on plasma membrane (Rattus norvegicus)
MAP kinase activation (Rattus norvegicus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Rattus norvegicus)
Activated TAK1 phosphorylates MKK4/MKK7 (Rattus norvegicus)
Activated TAK complexes [cytosol] (Rattus norvegicus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Rattus norvegicus)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Rattus norvegicus)
UBE2N:UBE2V1 [cytosol] (Rattus norvegicus)
activated TAK1 mediates p38 MAPK activation (Rattus norvegicus)
activated human TAK1 phosphorylates MKK3/MKK6 (Rattus norvegicus)
Activated TAK complexes [cytosol] (Rattus norvegicus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Rattus norvegicus)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Rattus norvegicus)
UBE2N:UBE2V1 [cytosol] (Rattus norvegicus)
Toll Like Receptor 2 (TLR2) Cascade (Rattus norvegicus)
Toll Like Receptor TLR1:TLR2 Cascade (Rattus norvegicus)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Rattus norvegicus)
MAP kinase activation (Rattus norvegicus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Rattus norvegicus)
Activated TAK1 phosphorylates MKK4/MKK7 (Rattus norvegicus)
Activated TAK complexes [cytosol] (Rattus norvegicus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Rattus norvegicus)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Rattus norvegicus)
UBE2N:UBE2V1 [cytosol] (Rattus norvegicus)
activated TAK1 mediates p38 MAPK activation (Rattus norvegicus)
activated human TAK1 phosphorylates MKK3/MKK6 (Rattus norvegicus)
Activated TAK complexes [cytosol] (Rattus norvegicus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Rattus norvegicus)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Rattus norvegicus)
UBE2N:UBE2V1 [cytosol] (Rattus norvegicus)
Toll Like Receptor TLR6:TLR2 Cascade (Rattus norvegicus)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Rattus norvegicus)
MAP kinase activation (Rattus norvegicus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Rattus norvegicus)
Activated TAK1 phosphorylates MKK4/MKK7 (Rattus norvegicus)
Activated TAK complexes [cytosol] (Rattus norvegicus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Rattus norvegicus)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Rattus norvegicus)
UBE2N:UBE2V1 [cytosol] (Rattus norvegicus)
activated TAK1 mediates p38 MAPK activation (Rattus norvegicus)
activated human TAK1 phosphorylates MKK3/MKK6 (Rattus norvegicus)
Activated TAK complexes [cytosol] (Rattus norvegicus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Rattus norvegicus)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Rattus norvegicus)
UBE2N:UBE2V1 [cytosol] (Rattus norvegicus)
Toll Like Receptor 3 (TLR3) Cascade (Rattus norvegicus)
MAP kinase activation (Rattus norvegicus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Rattus norvegicus)
Activated TAK1 phosphorylates MKK4/MKK7 (Rattus norvegicus)
Activated TAK complexes [cytosol] (Rattus norvegicus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Rattus norvegicus)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Rattus norvegicus)
UBE2N:UBE2V1 [cytosol] (Rattus norvegicus)
activated TAK1 mediates p38 MAPK activation (Rattus norvegicus)
activated human TAK1 phosphorylates MKK3/MKK6 (Rattus norvegicus)
Activated TAK complexes [cytosol] (Rattus norvegicus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Rattus norvegicus)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Rattus norvegicus)
UBE2N:UBE2V1 [cytosol] (Rattus norvegicus)
Toll Like Receptor 4 (TLR4) Cascade (Rattus norvegicus)
MyD88-independent TLR4 cascade (Rattus norvegicus)
TRIF (TICAM1)-mediated TLR4 signaling (Rattus norvegicus)
MAP kinase activation (Rattus norvegicus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Rattus norvegicus)
Activated TAK1 phosphorylates MKK4/MKK7 (Rattus norvegicus)
Activated TAK complexes [cytosol] (Rattus norvegicus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Rattus norvegicus)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Rattus norvegicus)
UBE2N:UBE2V1 [cytosol] (Rattus norvegicus)
activated TAK1 mediates p38 MAPK activation (Rattus norvegicus)
activated human TAK1 phosphorylates MKK3/MKK6 (Rattus norvegicus)
Activated TAK complexes [cytosol] (Rattus norvegicus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Rattus norvegicus)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Rattus norvegicus)
UBE2N:UBE2V1 [cytosol] (Rattus norvegicus)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Rattus norvegicus)
MAP kinase activation (Rattus norvegicus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Rattus norvegicus)
Activated TAK1 phosphorylates MKK4/MKK7 (Rattus norvegicus)
Activated TAK complexes [cytosol] (Rattus norvegicus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Rattus norvegicus)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Rattus norvegicus)
UBE2N:UBE2V1 [cytosol] (Rattus norvegicus)
activated TAK1 mediates p38 MAPK activation (Rattus norvegicus)
activated human TAK1 phosphorylates MKK3/MKK6 (Rattus norvegicus)
Activated TAK complexes [cytosol] (Rattus norvegicus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Rattus norvegicus)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Rattus norvegicus)
UBE2N:UBE2V1 [cytosol] (Rattus norvegicus)
Toll Like Receptor 5 (TLR5) Cascade (Rattus norvegicus)
MyD88 cascade initiated on plasma membrane (Rattus norvegicus)
MAP kinase activation (Rattus norvegicus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Rattus norvegicus)
Activated TAK1 phosphorylates MKK4/MKK7 (Rattus norvegicus)
Activated TAK complexes [cytosol] (Rattus norvegicus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Rattus norvegicus)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Rattus norvegicus)
UBE2N:UBE2V1 [cytosol] (Rattus norvegicus)
activated TAK1 mediates p38 MAPK activation (Rattus norvegicus)
activated human TAK1 phosphorylates MKK3/MKK6 (Rattus norvegicus)
Activated TAK complexes [cytosol] (Rattus norvegicus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Rattus norvegicus)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Rattus norvegicus)
UBE2N:UBE2V1 [cytosol] (Rattus norvegicus)
Toll Like Receptor 7/8 (TLR7/8) Cascade (Rattus norvegicus)
MyD88 dependent cascade initiated on endosome (Rattus norvegicus)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Rattus norvegicus)
MAP kinase activation (Rattus norvegicus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Rattus norvegicus)
Activated TAK1 phosphorylates MKK4/MKK7 (Rattus norvegicus)
Activated TAK complexes [cytosol] (Rattus norvegicus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Rattus norvegicus)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Rattus norvegicus)
UBE2N:UBE2V1 [cytosol] (Rattus norvegicus)
activated TAK1 mediates p38 MAPK activation (Rattus norvegicus)
activated human TAK1 phosphorylates MKK3/MKK6 (Rattus norvegicus)
Activated TAK complexes [cytosol] (Rattus norvegicus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Rattus norvegicus)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Rattus norvegicus)
UBE2N:UBE2V1 [cytosol] (Rattus norvegicus)
Toll Like Receptor 9 (TLR9) Cascade (Rattus norvegicus)
MyD88 dependent cascade initiated on endosome (Rattus norvegicus)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Rattus norvegicus)
MAP kinase activation (Rattus norvegicus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Rattus norvegicus)
Activated TAK1 phosphorylates MKK4/MKK7 (Rattus norvegicus)
Activated TAK complexes [cytosol] (Rattus norvegicus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Rattus norvegicus)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Rattus norvegicus)
UBE2N:UBE2V1 [cytosol] (Rattus norvegicus)
activated TAK1 mediates p38 MAPK activation (Rattus norvegicus)
activated human TAK1 phosphorylates MKK3/MKK6 (Rattus norvegicus)
Activated TAK complexes [cytosol] (Rattus norvegicus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Rattus norvegicus)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Rattus norvegicus)
UBE2N:UBE2V1 [cytosol] (Rattus norvegicus)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
ENSRNOG00000067007 [cytosol]
(Rattus norvegicus)
Ghost homologue of UBE2N [cytosol]
(Rattus norvegicus)
Participates
as a component of
K63polyUb-hp-IRAK1:p-Pellino-1,2,(3):UBE2N:UBE2V1 [cytosol] (Rattus norvegicus)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Rattus norvegicus)
Ub:UBE2N:UBE2V1 [cytosol] (Rattus norvegicus)
UBE2N:UBE2V1:PRKN [cytosol] (Rattus norvegicus)
Inferred From
UBE2N:UBE2V1 [cytosol]
(Homo sapiens)
© 2024
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