Reactome | Dctn6 [cytosol]

Dctn6 [cytosol]

Stable Identifier

R-RNO-2029035

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

cytosol

Synonyms

DCTN6, A0A8I5Y4I3

Locations in the PathwayBrowser

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Cellular responses to stimuli (Rattus norvegicus)

- Cellular responses to stress (Rattus norvegicus)
  - HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand (Rattus norvegicus)
    - HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus (Rattus norvegicus)
      - Dynein:Dynactin:microtubule [cytosol] (Rattus norvegicus)
        
        Dynactin [cytosol] (Rattus norvegicus)
        
        Dynactin rod [cytosol] (Rattus norvegicus)
        
        ACTR10:DCTN4:DCTN5:DCTN6 [cytosol] (Rattus norvegicus)
        
        Pointed end complex [cytosol] (Rattus norvegicus)
        
        Dctn6 [cytosol] (Rattus norvegicus)

Immune System (Rattus norvegicus)

- Adaptive Immune System (Rattus norvegicus)
  - MHC class II antigen presentation (Rattus norvegicus)
    - Transport of antigen loaded MHC II molecules to surface (Rattus norvegicus)
      - Dynein:Dynactin:microtubule [cytosol] (Rattus norvegicus)
        
        Dynactin [cytosol] (Rattus norvegicus)
        
        Dynactin rod [cytosol] (Rattus norvegicus)
        
        ACTR10:DCTN4:DCTN5:DCTN6 [cytosol] (Rattus norvegicus)
        
        Pointed end complex [cytosol] (Rattus norvegicus)
        
        Dctn6 [cytosol] (Rattus norvegicus)
      - Kinesins:Dynactin:microtubule [cytosol] (Rattus norvegicus)
        
        Dynactin [cytosol] (Rattus norvegicus)
        
        Dynactin rod [cytosol] (Rattus norvegicus)
        
        ACTR10:DCTN4:DCTN5:DCTN6 [cytosol] (Rattus norvegicus)
        
        Pointed end complex [cytosol] (Rattus norvegicus)
        
        Dctn6 [cytosol] (Rattus norvegicus)

Metabolism of proteins (Rattus norvegicus)

- Post-translational protein modification (Rattus norvegicus)
  - Asparagine N-linked glycosylation (Rattus norvegicus)
    - Transport to the Golgi and subsequent modification (Rattus norvegicus)
      - ER to Golgi Anterograde Transport (Rattus norvegicus)
        
        COPI-mediated anterograde transport (Rattus norvegicus)
        
        ERGIC-to-Golgi vesicles bind dynein:dynactin (Rattus norvegicus)
        
        Dynein:Dynactin:microtubule [cytosol] (Rattus norvegicus)
        
        Dynactin [cytosol] (Rattus norvegicus)
        
        Dynactin rod [cytosol] (Rattus norvegicus)
        
        ACTR10:DCTN4:DCTN5:DCTN6 [cytosol] (Rattus norvegicus)
        
        Pointed end complex [cytosol] (Rattus norvegicus)
        
        Dctn6 [cytosol] (Rattus norvegicus)
        
        RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Rattus norvegicus)
        
        Dynein:Dynactin:microtubule [cytosol] (Rattus norvegicus)
        
        Dynactin [cytosol] (Rattus norvegicus)
        
        Dynactin rod [cytosol] (Rattus norvegicus)
        
        ACTR10:DCTN4:DCTN5:DCTN6 [cytosol] (Rattus norvegicus)
        
        Pointed end complex [cytosol] (Rattus norvegicus)
        
        Dctn6 [cytosol] (Rattus norvegicus)
        
        Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex (Rattus norvegicus)
        
        Dynein:Dynactin:microtubule [cytosol] (Rattus norvegicus)
        
        Dynactin [cytosol] (Rattus norvegicus)
        
        Dynactin rod [cytosol] (Rattus norvegicus)
        
        ACTR10:DCTN4:DCTN5:DCTN6 [cytosol] (Rattus norvegicus)
        
        Pointed end complex [cytosol] (Rattus norvegicus)
        
        Dctn6 [cytosol] (Rattus norvegicus)
        
        RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Rattus norvegicus)
        
        Dynein:Dynactin:microtubule [cytosol] (Rattus norvegicus)
        
        Dynactin [cytosol] (Rattus norvegicus)
        
        Dynactin rod [cytosol] (Rattus norvegicus)
        
        ACTR10:DCTN4:DCTN5:DCTN6 [cytosol] (Rattus norvegicus)
        
        Pointed end complex [cytosol] (Rattus norvegicus)
        
        Dctn6 [cytosol] (Rattus norvegicus)

Vesicle-mediated transport (Rattus norvegicus)

- Membrane Trafficking (Rattus norvegicus)
  - ER to Golgi Anterograde Transport (Rattus norvegicus)
    - COPI-mediated anterograde transport (Rattus norvegicus)
      - ERGIC-to-Golgi vesicles bind dynein:dynactin (Rattus norvegicus)
        
        Dynein:Dynactin:microtubule [cytosol] (Rattus norvegicus)
        
        Dynactin [cytosol] (Rattus norvegicus)
        
        Dynactin rod [cytosol] (Rattus norvegicus)
        
        ACTR10:DCTN4:DCTN5:DCTN6 [cytosol] (Rattus norvegicus)
        
        Pointed end complex [cytosol] (Rattus norvegicus)
        
        Dctn6 [cytosol] (Rattus norvegicus)
        
        RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Rattus norvegicus)
        
        Dynein:Dynactin:microtubule [cytosol] (Rattus norvegicus)
        
        Dynactin [cytosol] (Rattus norvegicus)
        
        Dynactin rod [cytosol] (Rattus norvegicus)
        
        ACTR10:DCTN4:DCTN5:DCTN6 [cytosol] (Rattus norvegicus)
        
        Pointed end complex [cytosol] (Rattus norvegicus)
        
        Dctn6 [cytosol] (Rattus norvegicus)
      - Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex (Rattus norvegicus)
        
        Dynein:Dynactin:microtubule [cytosol] (Rattus norvegicus)
        
        Dynactin [cytosol] (Rattus norvegicus)
        
        Dynactin rod [cytosol] (Rattus norvegicus)
        
        ACTR10:DCTN4:DCTN5:DCTN6 [cytosol] (Rattus norvegicus)
        
        Pointed end complex [cytosol] (Rattus norvegicus)
        
        Dctn6 [cytosol] (Rattus norvegicus)
        
        RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Rattus norvegicus)
        
        Dynein:Dynactin:microtubule [cytosol] (Rattus norvegicus)
        
        Dynactin [cytosol] (Rattus norvegicus)
        
        Dynactin rod [cytosol] (Rattus norvegicus)
        
        ACTR10:DCTN4:DCTN5:DCTN6 [cytosol] (Rattus norvegicus)
        
        Pointed end complex [cytosol] (Rattus norvegicus)
        
        Dctn6 [cytosol] (Rattus norvegicus)
  - Intra-Golgi and retrograde Golgi-to-ER traffic (Rattus norvegicus)
    - Golgi-to-ER retrograde transport (Rattus norvegicus)
      - COPI-independent Golgi-to-ER retrograde traffic (Rattus norvegicus)
        
        Dynein drives COPI-independent retrograde traffic from the Golgi to the ER (Rattus norvegicus)
        
        Dynein:Dynactin:microtubule [cytosol] (Rattus norvegicus)
        
        Dynactin [cytosol] (Rattus norvegicus)
        
        Dynactin rod [cytosol] (Rattus norvegicus)
        
        ACTR10:DCTN4:DCTN5:DCTN6 [cytosol] (Rattus norvegicus)
        
        Pointed end complex [cytosol] (Rattus norvegicus)
        
        Dctn6 [cytosol] (Rattus norvegicus)
        
        RAB6:GTP:BICD dimer:COPI-independent retrograde cargo:Dynein:Dynactin:microtubules [Golgi membrane] (Rattus norvegicus)
        
        Dynein:Dynactin:microtubule [cytosol] (Rattus norvegicus)
        
        Dynactin [cytosol] (Rattus norvegicus)
        
        Dynactin rod [cytosol] (Rattus norvegicus)
        
        ACTR10:DCTN4:DCTN5:DCTN6 [cytosol] (Rattus norvegicus)
        
        Pointed end complex [cytosol] (Rattus norvegicus)
        
        Dctn6 [cytosol] (Rattus norvegicus)
        
        RAB6:GTP displaces PAFAH1B1 from dynein:dynactin complex (Rattus norvegicus)
        
        Dynein:Dynactin:microtubules:PAFAH1B1 [cytosol] (Rattus norvegicus)
        
        Dynein:Dynactin:microtubule [cytosol] (Rattus norvegicus)
        
        Dynactin [cytosol] (Rattus norvegicus)
        
        Dynactin rod [cytosol] (Rattus norvegicus)
        
        ACTR10:DCTN4:DCTN5:DCTN6 [cytosol] (Rattus norvegicus)
        
        Pointed end complex [cytosol] (Rattus norvegicus)
        
        Dctn6 [cytosol] (Rattus norvegicus)
        
        RAB6:GTP:BICD dimer:COPI-independent retrograde cargo:Dynein:Dynactin:microtubules [Golgi membrane] (Rattus norvegicus)
        
        Dynein:Dynactin:microtubule [cytosol] (Rattus norvegicus)
        
        Dynactin [cytosol] (Rattus norvegicus)
        
        Dynactin rod [cytosol] (Rattus norvegicus)
        
        ACTR10:DCTN4:DCTN5:DCTN6 [cytosol] (Rattus norvegicus)
        
        Pointed end complex [cytosol] (Rattus norvegicus)
        
        Dctn6 [cytosol] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:A0A8I5Y4I3

Gene Names

Dctn6

Reference Genes

ENSEMBL:ENSRNOG00000013254

ENSEMBL:ENSRNOG00000013254.8 Dctn6

Other Identifiers

10788559

1371533_at

17708301

290798

5647733

5749777

5857828

6016669

6561283

6584044

6600724

6658705

A_44_P377492

GE1178556

GO:0005813

GO:0005815

GO:0005856

GO:0005869

GO:0043226

ILMN_1358192

PH_rn_0007744

rc_AI175025_at

Participates

as a component of

Pointed end complex [cytosol] (Rattus norvegicus)

Inferred From

DCTN6 [cytosol] (Homo sapiens)

Cross References

Ensembl

ENSRNOP00000076456, ENSRNOG00000013254, ENSRNOT00000107106

RGD

1307549

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