Reactome | p-Y-WAVE [cytosol]

p-Y-WAVE [cytosol]

Stable Identifier

R-RNO-2029107

Type

Set [CandidateSet]

Species

Rattus norvegicus

Compartment

cytosol

Locations in the PathwayBrowser

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Immune System (Rattus norvegicus)

- Innate Immune System (Rattus norvegicus)
  - Fcgamma receptor (FCGR) dependent phagocytosis (Rattus norvegicus)
    - Regulation of actin dynamics for phagocytic cup formation (Rattus norvegicus)
      - (WASPs, WAVE):G-actin:ARP2/3 binds F-actin (Rattus norvegicus)
        
        Mother filament:branching complex [cytosol] (Rattus norvegicus)
        
        WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Rattus norvegicus)
        
        WAVE2, WASP, N-WASP [plasma membrane] (Rattus norvegicus)
        
        p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Rattus norvegicus)
        
        p-Y-WRC [cytosol] (Rattus norvegicus)
        
        p-Y-WAVE [cytosol] (Rattus norvegicus)
        
        WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Rattus norvegicus)
        
        WAVE2, WASP, N-WASP [plasma membrane] (Rattus norvegicus)
        
        p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Rattus norvegicus)
        
        p-Y-WRC [cytosol] (Rattus norvegicus)
        
        p-Y-WAVE [cytosol] (Rattus norvegicus)
      - ABL phosphorylates WAVEs (Rattus norvegicus)
        
        p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Rattus norvegicus)
        
        p-Y-WRC [cytosol] (Rattus norvegicus)
        
        p-Y-WAVE [cytosol] (Rattus norvegicus)
      - Detachment of WASP/WAVE (Rattus norvegicus)
        
        Mother filament:branching complex [cytosol] (Rattus norvegicus)
        
        WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Rattus norvegicus)
        
        WAVE2, WASP, N-WASP [plasma membrane] (Rattus norvegicus)
        
        p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Rattus norvegicus)
        
        p-Y-WRC [cytosol] (Rattus norvegicus)
        
        p-Y-WAVE [cytosol] (Rattus norvegicus)
        
        WAVE2, WASP, N-WASP [plasma membrane] (Rattus norvegicus)
        
        p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Rattus norvegicus)
        
        p-Y-WRC [cytosol] (Rattus norvegicus)
        
        p-Y-WAVE [cytosol] (Rattus norvegicus)
      - p-ERK phosphorylates WAVEs and ABI (Rattus norvegicus)
        
        p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Rattus norvegicus)
        
        p-Y-WRC [cytosol] (Rattus norvegicus)
        
        p-Y-WAVE [cytosol] (Rattus norvegicus)

Signal Transduction (Rattus norvegicus)

- Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Rattus norvegicus)
  - Signaling by Rho GTPases (Rattus norvegicus)
    - RHO GTPase Effectors (Rattus norvegicus)
      - RHO GTPases Activate WASPs and WAVEs (Rattus norvegicus)
        
        (WASPs, WAVE):G-actin:ARP2/3 binds F-actin (Rattus norvegicus)
        
        Mother filament:branching complex [cytosol] (Rattus norvegicus)
        
        WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Rattus norvegicus)
        
        WAVE2, WASP, N-WASP [plasma membrane] (Rattus norvegicus)
        
        p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Rattus norvegicus)
        
        p-Y-WRC [cytosol] (Rattus norvegicus)
        
        p-Y-WAVE [cytosol] (Rattus norvegicus)
        
        WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Rattus norvegicus)
        
        WAVE2, WASP, N-WASP [plasma membrane] (Rattus norvegicus)
        
        p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Rattus norvegicus)
        
        p-Y-WRC [cytosol] (Rattus norvegicus)
        
        p-Y-WAVE [cytosol] (Rattus norvegicus)
        
        ABL phosphorylates WAVEs (Rattus norvegicus)
        
        p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Rattus norvegicus)
        
        p-Y-WRC [cytosol] (Rattus norvegicus)
        
        p-Y-WAVE [cytosol] (Rattus norvegicus)
        
        Detachment of WASP/WAVE (Rattus norvegicus)
        
        Mother filament:branching complex [cytosol] (Rattus norvegicus)
        
        WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Rattus norvegicus)
        
        WAVE2, WASP, N-WASP [plasma membrane] (Rattus norvegicus)
        
        p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Rattus norvegicus)
        
        p-Y-WRC [cytosol] (Rattus norvegicus)
        
        p-Y-WAVE [cytosol] (Rattus norvegicus)
        
        WAVE2, WASP, N-WASP [plasma membrane] (Rattus norvegicus)
        
        p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Rattus norvegicus)
        
        p-Y-WRC [cytosol] (Rattus norvegicus)
        
        p-Y-WAVE [cytosol] (Rattus norvegicus)
        
        p-ERK phosphorylates WAVEs and ABI (Rattus norvegicus)
        
        p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Rattus norvegicus)
        
        p-Y-WRC [cytosol] (Rattus norvegicus)
        
        p-Y-WAVE [cytosol] (Rattus norvegicus)

Participants

members

phospho-Wasf2 [cytosol] (Rattus norvegicus)

candidates

Participates

as a component of

p-Y-WRC [cytosol] (Rattus norvegicus)

Inferred From

p-Y-WAVE [cytosol] (Homo sapiens)