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Grb7 [cytosol]
Stable Identifier
R-RNO-204819
Type
Protein [EntityWithAccessionedSequence]
Species
Rattus norvegicus
Compartment
cytosol
Synonyms
GRB7, Q9QZC5
Locations in the PathwayBrowser
Expand all
Developmental Biology (Rattus norvegicus)
Nervous system development (Rattus norvegicus)
Axon guidance (Rattus norvegicus)
RET signaling (Rattus norvegicus)
2x p-5Y-RET:GDNF:GFRA complexes bind GRB7,10 (Rattus norvegicus)
2x p-5Y-RET:GDNF:GFRA complexes:GRB7,GRB10 [plasma membrane] (Rattus norvegicus)
GRB7,GRB10 [cytosol] (Rattus norvegicus)
Grb7 [cytosol] (Rattus norvegicus)
GRB7,GRB10 [cytosol] (Rattus norvegicus)
Grb7 [cytosol] (Rattus norvegicus)
Hemostasis (Rattus norvegicus)
Cell surface interactions at the vascular wall (Rattus norvegicus)
Tie2 Signaling (Rattus norvegicus)
Interaction of Tie2 and Grb7 (Rattus norvegicus)
Grb7 [cytosol] (Rattus norvegicus)
Tie2:Grb7 complex [plasma membrane] (Rattus norvegicus)
Grb7 [cytosol] (Rattus norvegicus)
Signal Transduction (Rattus norvegicus)
Signaling by Receptor Tyrosine Kinases (Rattus norvegicus)
Signaling by ERBB2 (Rattus norvegicus)
GRB7 events in ERBB2 signaling (Rattus norvegicus)
GRB7 binds phosphorylated heterodimer of ERBB2 and ERBB3 (Rattus norvegicus)
Grb7 [cytosol] (Rattus norvegicus)
NRG1/2:p-10Y-ERBB3:p-ERBB2:GRB7 [plasma membrane] (Rattus norvegicus)
Grb7 [cytosol] (Rattus norvegicus)
Signaling by PDGF (Rattus norvegicus)
Downstream signal transduction (Rattus norvegicus)
Grb7 binds to the active PDGF receptor (Rattus norvegicus)
Grb7 [cytosol] (Rattus norvegicus)
PDGF:Phospho-PDGF receptor dimer:Grb7 [plasma membrane] (Rattus norvegicus)
Grb7 [cytosol] (Rattus norvegicus)
Signaling by SCF-KIT (Rattus norvegicus)
Interaction of other adapter proteins with p-KIT (Rattus norvegicus)
Adapter proteins [cytosol] (Rattus norvegicus)
Grb7 [cytosol] (Rattus norvegicus)
Adapter proteins:p-KIT complex [plasma membrane] (Rattus norvegicus)
Adapter proteins [cytosol] (Rattus norvegicus)
Grb7 [cytosol] (Rattus norvegicus)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Rattus norvegicus)
Signaling by Rho GTPases (Rattus norvegicus)
RHO GTPase cycle (Rattus norvegicus)
RND1 GTPase cycle (Rattus norvegicus)
RND1 binds effectors (Rattus norvegicus)
RND1 effectors [cytosol] (Rattus norvegicus)
Grb7 [cytosol] (Rattus norvegicus)
RND1:GTP:RND1 effectors [plasma membrane] (Rattus norvegicus)
RND1 effectors [cytosol] (Rattus norvegicus)
Grb7 [cytosol] (Rattus norvegicus)
External Reference Information
External Reference
UniProt:Q9QZC5
Gene Names
Grb7
Reference Genes
BioGPS Gene:84427 Grb7
ENSEMBL:ENSRNOG00000006990
KEGG Gene (Rattus norvegicus):84427 Grb7
Monarch:84427 Grb7
NCBI Gene:84427 Grb7
UCSC:Q9QZC5 Grb7
Reference Transcript
RefSeq:XM_017597560.1 Grb7
RefSeq:XM_017597559.1 Grb7
RefSeq:XM_008768125.1 Grb7
RefSeq:XM_006247433.3 Grb7
RefSeq:XM_006247432.3 Grb7
RefSeq:NM_053403.2 Grb7
RefSeq:XM_017597561.1 Grb7
Participates
as a member of
RND1 effectors [cytosol] (Rattus norvegicus)
GRB7,GRB10 [cytosol] (Rattus norvegicus)
Adapter proteins [cytosol] (Rattus norvegicus)
as an input of
Interaction of Tie2 and Grb7 (Rattus norvegicus)
GRB7 binds phosphorylated heterodimer of ERBB2 and ERBB3 (Rattus norvegicus)
Grb7 binds to the active PDGF receptor (Rattus norvegicus)
as a component of
Tie2:Grb7 complex [plasma membrane] (Rattus norvegicus)
NRG1/2:p-10Y-ERBB3:p-ERBB2:GRB7 [plasma membrane] (Rattus norvegicus)
PDGF:Phospho-PDGF receptor dimer:Grb7 [plasma membrane] (Rattus norvegicus)
Inferred From
GRB7 [cytosol]
(Homo sapiens)
Cross References
RefSeq
XP_008766347.1
,
XP_017453050.1
,
XP_017453048.1
,
XP_006247494.1
,
XP_006247495.1
,
XP_017453049.1
,
NP_445855.1
PRO
Q9QZC5
RGD
619759
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P00533 EGFR
20
p-6Y-EGFR [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869138)
p-5Y-EGFRvIII [plasma membrane]
(R-HSA-1248649)
EGFRvIII [plasma membrane]
(R-HSA-1214162)
p-6Y-EGFR E746_A750del;T790M [plasma membrane]
(R-HSA-1182985)
p-6Y-EGFR L858R;T790M [plasma membrane]
(R-HSA-1182984)
p-6Y-EGFR A767_V769dup [plasma membrane]
(R-HSA-1996343)
p-6Y-EGFR N771_H773dup [plasma membrane]
(R-HSA-1996342)
p-6Y-EGFR K739_I744dup [plasma membrane]
(R-HSA-1996346)
p-6Y-EGFR D770_N771insNPG [plasma membrane]
(R-HSA-1996335)
p-6Y-EGFR E746_A750del [plasma membrane]
(R-HSA-1181214)
p-6Y-EGFR L858R [plasma membrane]
(R-HSA-1173211)
p-6Y-EGFR G719S [plasma membrane]
(R-HSA-1169417)
p-6Y-EGFR L747_P753delinsS [plasma membrane]
(R-HSA-1228038)
p-6Y-EGFR L747_A750delinsP [plasma membrane]
(R-HSA-1228044)
p-6Y-EGFR L747_T751del [plasma membrane]
(R-HSA-1228041)
p-6Y-EGFR L747_S752del [plasma membrane]
(R-HSA-1228040)
p-6Y-EGFR L747_T751delinsP [plasma membrane]
(R-HSA-1228042)
p-6Y-EGFR E746_T751delinsA [plasma membrane]
(R-HSA-1228037)
p-6Y-EGFR E746_S752delinsV [plasma membrane]
(R-HSA-1228039)
p-6Y-EGFR L861Q [plasma membrane]
(R-HSA-1177541)
0.499
7
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