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Integrin alphaVbeta3 [plasma membrane]
Stable Identifier
R-RNO-210216
Type
Complex
Species
Rattus norvegicus
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Cellular responses to stimuli (Rattus norvegicus)
Cellular responses to mechanical stimuli (Rattus norvegicus)
Response of endothelial cells to shear stress (Rattus norvegicus)
Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells (Rattus norvegicus)
Phosphorylation of PTK2 (FAK) on tyrosine-397 in response to turbulent blood flow (Rattus norvegicus)
Integrin alphaVbeta3 [plasma membrane] (Rattus norvegicus)
Developmental Biology (Rattus norvegicus)
Nervous system development (Rattus norvegicus)
Axon guidance (Rattus norvegicus)
L1CAM interactions (Rattus norvegicus)
Signal transduction by L1 (Rattus norvegicus)
L1 interaction with Integrins (Rattus norvegicus)
Integrins [plasma membrane] (Rattus norvegicus)
Integrin alphaVbeta3 [plasma membrane] (Rattus norvegicus)
L1:Integrin complex [plasma membrane] (Rattus norvegicus)
Integrins [plasma membrane] (Rattus norvegicus)
Integrin alphaVbeta3 [plasma membrane] (Rattus norvegicus)
Extracellular matrix organization (Rattus norvegicus)
ECM proteoglycans (Rattus norvegicus)
Dentin matrix protein 1 binds integrin alphaVbeta3 (Rattus norvegicus)
DMP1:Integrin alphVbeta3 [plasma membrane] (Rattus norvegicus)
Integrin alphaVbeta3 [plasma membrane] (Rattus norvegicus)
Integrin alphaVbeta3 [plasma membrane] (Rattus norvegicus)
TNC binds Integrin alphaVbeta3, alphaVbeta6, alpha2beta1, alpha7beta1, alpha8beta1, alpha9beta1, alphaXbeta1 (Rattus norvegicus)
Integrin alphaVbeta3, alphaVbeta6, alpha2beta1, alpha7beta1, alpha8beta1, alpha9beta1, alphaXbeta1 [plasma membrane] (Rattus norvegicus)
Integrin alphaVbeta3 [plasma membrane] (Rattus norvegicus)
TNC:Integrin alphaVbeta3, alphaVbeta6, alpha2beta1, alpha7beta1, alpha8beta1, alpha9beta1, alphaXbeta1 [plasma membrane] (Rattus norvegicus)
Integrin alphaVbeta3, alphaVbeta6, alpha2beta1, alpha7beta1, alpha8beta1, alpha9beta1, alphaXbeta1 [plasma membrane] (Rattus norvegicus)
Integrin alphaVbeta3 [plasma membrane] (Rattus norvegicus)
VTN binds integrins alphaVbeta1, alphaVbeta3, alpha3beta5, alphaIIBbeta3 (Rattus norvegicus)
Integrins alphaVbeta1, alphaVbeta3, alphaVbeta5, alpha2bbeta3 [plasma membrane] (Rattus norvegicus)
Integrin alphaVbeta3 [plasma membrane] (Rattus norvegicus)
VTN:Integrins alphaVbeta1, alphaVbeta3, alphaVbeta5, alpha2bbeta3 [plasma membrane] (Rattus norvegicus)
Integrins alphaVbeta1, alphaVbeta3, alphaVbeta5, alpha2bbeta3 [plasma membrane] (Rattus norvegicus)
Integrin alphaVbeta3 [plasma membrane] (Rattus norvegicus)
Elastic fibre formation (Rattus norvegicus)
Fibrillin-1 binds integrins (Rattus norvegicus)
Fibrilin-1:Fibrilin-binding integrins [plasma membrane] (Rattus norvegicus)
Fibrilin-binding integrins [plasma membrane] (Rattus norvegicus)
Integrin alphaVbeta3 [plasma membrane] (Rattus norvegicus)
Fibrilin-binding integrins [plasma membrane] (Rattus norvegicus)
Integrin alphaVbeta3 [plasma membrane] (Rattus norvegicus)
Molecules associated with elastic fibres (Rattus norvegicus)
Latent TGF-beta-1 binds integrins (Rattus norvegicus)
LAP1 binding-integrins [plasma membrane] (Rattus norvegicus)
Integrin alphaVbeta3 [plasma membrane] (Rattus norvegicus)
LTBP1:TGFB1:LAP1:LAP1-binding integrins [plasma membrane] (Rattus norvegicus)
LAP1 binding-integrins [plasma membrane] (Rattus norvegicus)
Integrin alphaVbeta3 [plasma membrane] (Rattus norvegicus)
Latent TGF-beta-3 binds integrins (Rattus norvegicus)
LAP3-binding integrins [plasma membrane] (Rattus norvegicus)
Integrin alphaVbeta3 [plasma membrane] (Rattus norvegicus)
TGF-beta-3:LAP3:LAP3-binding integrins [plasma membrane] (Rattus norvegicus)
LAP3-binding integrins [plasma membrane] (Rattus norvegicus)
Integrin alphaVbeta3 [plasma membrane] (Rattus norvegicus)
Integrin cell surface interactions (Rattus norvegicus)
COMP binds Integrin alpha5beta1, Integrin alphaVbeta3, CD47 (Rattus norvegicus)
COMP pentamer:Integrin alpha5beta1, Integrin alphaVbeta3, CD47 [plasma membrane] (Rattus norvegicus)
Integrin alpha5beta1, Integrin alphaVbeta3, CD47 [plasma membrane] (Rattus norvegicus)
Integrin alphaVbeta3 [plasma membrane] (Rattus norvegicus)
Integrin alpha5beta1, Integrin alphaVbeta3, CD47 [plasma membrane] (Rattus norvegicus)
Integrin alphaVbeta3 [plasma membrane] (Rattus norvegicus)
Canstatin binds integrins alphaVbeta3, alphaVbeta5 (Rattus norvegicus)
Canstatin:Integrins alphaVbeta3, alphaVbeta5 [plasma membrane] (Rattus norvegicus)
Integrins alphaVbeta3, alphaVbeta5 [plasma membrane] (Rattus norvegicus)
Integrin alphaVbeta3 [plasma membrane] (Rattus norvegicus)
Integrins alphaVbeta3, alphaVbeta5 [plasma membrane] (Rattus norvegicus)
Integrin alphaVbeta3 [plasma membrane] (Rattus norvegicus)
Endostatin binds integrin alphaVbeta3, alphaVbeta5, alpha3beta1, alpha5beta1 (Rattus norvegicus)
Endostatin:Integrins alphaVbeta3, alphaVbeta5, alpha3beta1, alpha5beta1 [plasma membrane] (Rattus norvegicus)
Integrins alphaVbeta3, alphaVbeta5, alpha3beta1, alpha5beta1 [plasma membrane] (Rattus norvegicus)
Integrin alphaVbeta3 [plasma membrane] (Rattus norvegicus)
Integrins alphaVbeta3, alphaVbeta5, alpha3beta1, alpha5beta1 [plasma membrane] (Rattus norvegicus)
Integrin alphaVbeta3 [plasma membrane] (Rattus norvegicus)
Integrins alpha4beta1, alpha8beta1, alphaVbeta1, alphaVbeta3, alphaVbeta6 bind Fibronectin matrix (Rattus norvegicus)
Integrin alpha4beta1, alpha8beta1, alphaVbeta1, alphaVbeta3, alphaVbeta6 [plasma membrane] (Rattus norvegicus)
Integrin alphaVbeta3 [plasma membrane] (Rattus norvegicus)
Integrin alpha4beta1, alpha8beta1, alphaVbeta6:Fibronectin matrix [plasma membrane] (Rattus norvegicus)
Integrin alpha4beta1, alpha8beta1, alphaVbeta1, alphaVbeta3, alphaVbeta6 [plasma membrane] (Rattus norvegicus)
Integrin alphaVbeta3 [plasma membrane] (Rattus norvegicus)
Interaction of integrin alphaVbeta3 with Fibrillin (Rattus norvegicus)
Integrin alphaVbeta3 [plasma membrane] (Rattus norvegicus)
Integrin alphaVbeta3:Fibrillin-1 [plasma membrane] (Rattus norvegicus)
Integrin alphaVbeta3 [plasma membrane] (Rattus norvegicus)
Interaction of integrin alphaVbeta3 with IPSP (Bone sialoprotein 2) (Rattus norvegicus)
Integrin alphaVbeta3 [plasma membrane] (Rattus norvegicus)
Integrin alphaVbeta3:IBSP [plasma membrane] (Rattus norvegicus)
Integrin alphaVbeta3 [plasma membrane] (Rattus norvegicus)
Interaction of integrin alphaVbeta3 with PECAM1 (Rattus norvegicus)
Integrin alphaVbeta3 [plasma membrane] (Rattus norvegicus)
Integrin alphaVbeta3:PECAM1 [plasma membrane] (Rattus norvegicus)
Integrin alphaVbeta3 [plasma membrane] (Rattus norvegicus)
Interaction of integrin alphaVbeta3 with Tenascin (Rattus norvegicus)
Integrin alphaVbeta3 [plasma membrane] (Rattus norvegicus)
Integrin alphaVbeta3:Tenascin [plasma membrane] (Rattus norvegicus)
Integrin alphaVbeta3 [plasma membrane] (Rattus norvegicus)
Tetrastatin binds integrin alphaVbeta3 (Rattus norvegicus)
Integrin alphaVbeta3 [plasma membrane] (Rattus norvegicus)
Tetrastatin:Integrin alphaVbeta3 [plasma membrane] (Rattus norvegicus)
Integrin alphaVbeta3 [plasma membrane] (Rattus norvegicus)
Tumstatin binds integrin alphaVbeta 3, alpha3beta1 (Rattus norvegicus)
Integrins alphaVbeta3, alpha3beta1 [plasma membrane] (Rattus norvegicus)
Integrin alphaVbeta3 [plasma membrane] (Rattus norvegicus)
Tumstatin:Integrins alphaVbeta3, alpha3beta1 [plasma membrane] (Rattus norvegicus)
Integrins alphaVbeta3, alpha3beta1 [plasma membrane] (Rattus norvegicus)
Integrin alphaVbeta3 [plasma membrane] (Rattus norvegicus)
VTN (vitronectin) binds Integrin alphaVbeta3, alphaVbeta5, alphaVbeta8 (Rattus norvegicus)
Integrin alphaVbeta3, 5, 8 [plasma membrane] (Rattus norvegicus)
Integrin alphaVbeta3 [plasma membrane] (Rattus norvegicus)
VTN:Integrin alphaVbeta3, 5, 8 [plasma membrane] (Rattus norvegicus)
Integrin alphaVbeta3, 5, 8 [plasma membrane] (Rattus norvegicus)
Integrin alphaVbeta3 [plasma membrane] (Rattus norvegicus)
Non-integrin membrane-ECM interactions (Rattus norvegicus)
Syndecan interactions (Rattus norvegicus)
Syndecan-1 binds Integrins alpha2beta1, (alpha6beta4) (Rattus norvegicus)
Integrin alpha2beta1, (alpha6beta4) [plasma membrane] (Rattus norvegicus)
Integrin alphaVbeta3 [plasma membrane] (Rattus norvegicus)
Syndecan-1:Integrin alpha2beta1 (alpha6beta4) [plasma membrane] (Rattus norvegicus)
Integrin alpha2beta1, (alpha6beta4) [plasma membrane] (Rattus norvegicus)
Integrin alphaVbeta3 [plasma membrane] (Rattus norvegicus)
Hemostasis (Rattus norvegicus)
Cell surface interactions at the vascular wall (Rattus norvegicus)
PECAM1 interactions (Rattus norvegicus)
Interaction of integrin alphaVbeta3 with PECAM1 (Rattus norvegicus)
Integrin alphaVbeta3 [plasma membrane] (Rattus norvegicus)
Integrin alphaVbeta3:PECAM1 [plasma membrane] (Rattus norvegicus)
Integrin alphaVbeta3 [plasma membrane] (Rattus norvegicus)
Signal Transduction (Rattus norvegicus)
Signaling by Receptor Tyrosine Kinases (Rattus norvegicus)
Signaling by VEGF (Rattus norvegicus)
VEGFA-VEGFR2 Pathway (Rattus norvegicus)
Integrin alphaVbeta3 binds p-6Y-VEGFR2 (Rattus norvegicus)
Integrin alphaVbeta3 [plasma membrane] (Rattus norvegicus)
VEGFA:p-6Y-VEGFR2:Integrin alphaVbeta3 [plasma membrane] (Rattus norvegicus)
Integrin alphaVbeta3 [plasma membrane] (Rattus norvegicus)
PTK2beta binds alphaVbeta3 (Rattus norvegicus)
VEGFA:p-6Y-VEGFR2:Integrin alphaVbeta3 [plasma membrane] (Rattus norvegicus)
Integrin alphaVbeta3 [plasma membrane] (Rattus norvegicus)
VEGFA:p-6Y-VEGFR2:Integrin alphaVbeta3:PTK2B [plasma membrane] (Rattus norvegicus)
VEGFA:p-6Y-VEGFR2:Integrin alphaVbeta3 [plasma membrane] (Rattus norvegicus)
Integrin alphaVbeta3 [plasma membrane] (Rattus norvegicus)
SRC-1 phosphorylates PTK2-beta (Rattus norvegicus)
VEGFA:p-6Y-VEGFR2:Integrin alphaVbeta3:PTK2B [plasma membrane] (Rattus norvegicus)
VEGFA:p-6Y-VEGFR2:Integrin alphaVbeta3 [plasma membrane] (Rattus norvegicus)
Integrin alphaVbeta3 [plasma membrane] (Rattus norvegicus)
VEGFA:p-6Y-VEGFR2:Integrin alphaVbeta3:p-Y402-PTK2B [plasma membrane] (Rattus norvegicus)
VEGFA:p-6Y-VEGFR2:Integrin alphaVbeta3 [plasma membrane] (Rattus norvegicus)
Integrin alphaVbeta3 [plasma membrane] (Rattus norvegicus)
p-Y402-PTK2B phosphorylates p-5Y,S732-PTK2 on Y407 (Rattus norvegicus)
VEGFA:p-6Y-VEGFR2:Integrin alphaVbeta3:p-Y402-PTK2B [plasma membrane] (Rattus norvegicus)
VEGFA:p-6Y-VEGFR2:Integrin alphaVbeta3 [plasma membrane] (Rattus norvegicus)
Integrin alphaVbeta3 [plasma membrane] (Rattus norvegicus)
Signaling by TGFB family members (Rattus norvegicus)
Signaling by TGF-beta Receptor Complex (Rattus norvegicus)
TGF-beta receptor signaling activates SMADs (Rattus norvegicus)
Latent TGF-beta-1 binds integrins (Rattus norvegicus)
LAP1 binding-integrins [plasma membrane] (Rattus norvegicus)
Integrin alphaVbeta3 [plasma membrane] (Rattus norvegicus)
LTBP1:TGFB1:LAP1:LAP1-binding integrins [plasma membrane] (Rattus norvegicus)
LAP1 binding-integrins [plasma membrane] (Rattus norvegicus)
Integrin alphaVbeta3 [plasma membrane] (Rattus norvegicus)
Latent TGF-beta-3 binds integrins (Rattus norvegicus)
LAP3-binding integrins [plasma membrane] (Rattus norvegicus)
Integrin alphaVbeta3 [plasma membrane] (Rattus norvegicus)
TGF-beta-3:LAP3:LAP3-binding integrins [plasma membrane] (Rattus norvegicus)
LAP3-binding integrins [plasma membrane] (Rattus norvegicus)
Integrin alphaVbeta3 [plasma membrane] (Rattus norvegicus)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
Itgav [plasma membrane]
(Rattus norvegicus)
ITGB3 [plasma membrane]
(Rattus norvegicus)
Participates
as a member of
Integrin alphaVbeta3, alphaVbeta6, alpha2beta1, alpha7beta1, alpha8beta1, alpha9beta1, alphaXbeta1 [plasma membrane] (Rattus norvegicus)
Integrins alphaVbeta1, alphaVbeta3, alphaVbeta5, alpha2bbeta3 [plasma membrane] (Rattus norvegicus)
Integrin alpha2beta1, (alpha6beta4) [plasma membrane] (Rattus norvegicus)
Fibrilin-binding integrins [plasma membrane] (Rattus norvegicus)
Integrins [plasma membrane] (Rattus norvegicus)
Integrins alphaVbeta3, alphaVbeta5, alpha3beta1, alpha5beta1 [plasma membrane] (Rattus norvegicus)
Integrin alpha4beta1, alpha8beta1, alphaVbeta1, alphaVbeta3, alphaVbeta6 [plasma membrane] (Rattus norvegicus)
Integrins alphaVbeta3, alpha3beta1 [plasma membrane] (Rattus norvegicus)
Integrin alpha5beta1, Integrin alphaVbeta3, CD47 [plasma membrane] (Rattus norvegicus)
Integrin alphaVbeta3, 5, 8 [plasma membrane] (Rattus norvegicus)
Integrins alphaVbeta3, alphaVbeta5 [plasma membrane] (Rattus norvegicus)
LAP1 binding-integrins [plasma membrane] (Rattus norvegicus)
LAP3-binding integrins [plasma membrane] (Rattus norvegicus)
as an input of
Dentin matrix protein 1 binds integrin alphaVbeta3 (Rattus norvegicus)
Interaction of integrin alphaVbeta3 with IPSP (Bone sialoprotein 2) (Rattus norvegicus)
Interaction of integrin alphaVbeta3 with Tenascin (Rattus norvegicus)
Interaction of integrin alphaVbeta3 with Fibrillin (Rattus norvegicus)
Interaction of integrin alphaVbeta3 with PECAM1 (Rattus norvegicus)
Tetrastatin binds integrin alphaVbeta3 (Rattus norvegicus)
Integrin alphaVbeta3 binds p-6Y-VEGFR2 (Rattus norvegicus)
as a component of
DMP1:Integrin alphVbeta3 [plasma membrane] (Rattus norvegicus)
Integrin alphaVbeta3:IBSP [plasma membrane] (Rattus norvegicus)
Integrin alphaVbeta3:Tenascin [plasma membrane] (Rattus norvegicus)
Integrin alphaVbeta3:Fibrillin-1 [plasma membrane] (Rattus norvegicus)
Integrin alphaVbeta3:PECAM1 [plasma membrane] (Rattus norvegicus)
Tetrastatin:Integrin alphaVbeta3 [plasma membrane] (Rattus norvegicus)
VEGFA:p-6Y-VEGFR2:Integrin alphaVbeta3 [plasma membrane] (Rattus norvegicus)
This entity regulates
Positively
Phosphorylation of PTK2 (FAK) on tyrosine-397 in response to turbulent blood flow
(Rattus norvegicus)
Inferred From
Integrin alphaVbeta3 [plasma membrane]
(Homo sapiens)
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