Reactome | Uso1 [Golgi membrane]

Uso1 [Golgi membrane]

Stable Identifier

R-RNO-2167936

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

Golgi membrane

Synonyms

USO1, P41542

Locations in the PathwayBrowser

Expand all

Metabolism of proteins (Rattus norvegicus)

- Post-translational protein modification (Rattus norvegicus)
  - Asparagine N-linked glycosylation (Rattus norvegicus)
    - Transport to the Golgi and subsequent modification (Rattus norvegicus)
      - ER to Golgi Anterograde Transport (Rattus norvegicus)
        
        COPI-mediated anterograde transport (Rattus norvegicus)
        
        COPI vesicle uncoating (Rattus norvegicus)
        
        RAB1:GTP:USO1:coatomer:p24 dimers:cargo:spectrin:ankyrin:COG complex:GOLGA2:GORASP1:TMEM115:cis-SNARE complex [Golgi membrane] (Rattus norvegicus)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin:COG complex:GOLGA2:GORASP1:GOLGB1:TMEM115 [Golgi membrane] (Rattus norvegicus)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [Golgi membrane] (Rattus norvegicus)
        
        RAB1:GTP:USO1:coatomer [Golgi membrane] (Rattus norvegicus)
        
        RAB1:GTP:USO1 [Golgi membrane] (Rattus norvegicus)
        
        USO1 homodimer [Golgi membrane] (Rattus norvegicus)
        
        Uso1 [Golgi membrane] (Rattus norvegicus)
        
        Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex (Rattus norvegicus)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin:COG complex:GOLGA2:GORASP1:GOLGB1:TMEM115 [Golgi membrane] (Rattus norvegicus)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [Golgi membrane] (Rattus norvegicus)
        
        RAB1:GTP:USO1:coatomer [Golgi membrane] (Rattus norvegicus)
        
        RAB1:GTP:USO1 [Golgi membrane] (Rattus norvegicus)
        
        USO1 homodimer [Golgi membrane] (Rattus norvegicus)
        
        Uso1 [Golgi membrane] (Rattus norvegicus)
        
        cis-Golgi t-SNAREs bind YKT6 on tethered vesicle (Rattus norvegicus)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin:COG complex:GOLGA2:GORASP1:GOLGB1:TMEM115 [Golgi membrane] (Rattus norvegicus)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [Golgi membrane] (Rattus norvegicus)
        
        RAB1:GTP:USO1:coatomer [Golgi membrane] (Rattus norvegicus)
        
        RAB1:GTP:USO1 [Golgi membrane] (Rattus norvegicus)
        
        USO1 homodimer [Golgi membrane] (Rattus norvegicus)
        
        Uso1 [Golgi membrane] (Rattus norvegicus)
        
        RAB1:GTP:USO1:coatomer:p24 dimers:cargo:spectrin:ankyrin:COG complex:GOLGA2:GORASP1:TMEM115:cis-SNARE complex [Golgi membrane] (Rattus norvegicus)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin:COG complex:GOLGA2:GORASP1:GOLGB1:TMEM115 [Golgi membrane] (Rattus norvegicus)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [Golgi membrane] (Rattus norvegicus)
        
        RAB1:GTP:USO1:coatomer [Golgi membrane] (Rattus norvegicus)
        
        RAB1:GTP:USO1 [Golgi membrane] (Rattus norvegicus)
        
        USO1 homodimer [Golgi membrane] (Rattus norvegicus)
        
        Uso1 [Golgi membrane] (Rattus norvegicus)

Vesicle-mediated transport (Rattus norvegicus)

- Membrane Trafficking (Rattus norvegicus)
  - ER to Golgi Anterograde Transport (Rattus norvegicus)
    - COPI-mediated anterograde transport (Rattus norvegicus)
      - COPI vesicle uncoating (Rattus norvegicus)
        
        RAB1:GTP:USO1:coatomer:p24 dimers:cargo:spectrin:ankyrin:COG complex:GOLGA2:GORASP1:TMEM115:cis-SNARE complex [Golgi membrane] (Rattus norvegicus)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin:COG complex:GOLGA2:GORASP1:GOLGB1:TMEM115 [Golgi membrane] (Rattus norvegicus)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [Golgi membrane] (Rattus norvegicus)
        
        RAB1:GTP:USO1:coatomer [Golgi membrane] (Rattus norvegicus)
        
        RAB1:GTP:USO1 [Golgi membrane] (Rattus norvegicus)
        
        USO1 homodimer [Golgi membrane] (Rattus norvegicus)
        
        Uso1 [Golgi membrane] (Rattus norvegicus)
      - Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex (Rattus norvegicus)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin:COG complex:GOLGA2:GORASP1:GOLGB1:TMEM115 [Golgi membrane] (Rattus norvegicus)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [Golgi membrane] (Rattus norvegicus)
        
        RAB1:GTP:USO1:coatomer [Golgi membrane] (Rattus norvegicus)
        
        RAB1:GTP:USO1 [Golgi membrane] (Rattus norvegicus)
        
        USO1 homodimer [Golgi membrane] (Rattus norvegicus)
        
        Uso1 [Golgi membrane] (Rattus norvegicus)
      - cis-Golgi t-SNAREs bind YKT6 on tethered vesicle (Rattus norvegicus)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin:COG complex:GOLGA2:GORASP1:GOLGB1:TMEM115 [Golgi membrane] (Rattus norvegicus)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [Golgi membrane] (Rattus norvegicus)
        
        RAB1:GTP:USO1:coatomer [Golgi membrane] (Rattus norvegicus)
        
        RAB1:GTP:USO1 [Golgi membrane] (Rattus norvegicus)
        
        USO1 homodimer [Golgi membrane] (Rattus norvegicus)
        
        Uso1 [Golgi membrane] (Rattus norvegicus)
        
        RAB1:GTP:USO1:coatomer:p24 dimers:cargo:spectrin:ankyrin:COG complex:GOLGA2:GORASP1:TMEM115:cis-SNARE complex [Golgi membrane] (Rattus norvegicus)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin:COG complex:GOLGA2:GORASP1:GOLGB1:TMEM115 [Golgi membrane] (Rattus norvegicus)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [Golgi membrane] (Rattus norvegicus)
        
        RAB1:GTP:USO1:coatomer [Golgi membrane] (Rattus norvegicus)
        
        RAB1:GTP:USO1 [Golgi membrane] (Rattus norvegicus)
        
        USO1 homodimer [Golgi membrane] (Rattus norvegicus)
        
        Uso1 [Golgi membrane] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:P41542 Uso1

Gene Names

Uso1, Vdp

Chain

chain:1-959

Reference Genes

BioGPS Gene:56042 Uso1

KEGG:rno:56042 Uso1

Monarch:56042 Uso1

NCBI Gene:56042 Uso1

UCSC:P41542 Uso1

Reference Transcript

RefSeq:NM_019379.1 Uso1

Participates

as a component of

USO1 homodimer [Golgi membrane] (Rattus norvegicus)

Other forms of this molecule

Uso1 [transport vesicle]

Uso1 [ER to Golgi transport vesicle membrane]

Uso1 [Golgi membrane]

Uso1 [ER to Golgi transport vesicle membrane]

Uso1 [cytosol]

Inferred From

USO1 [Golgi membrane] (Homo sapiens)

Cross References

RefSeq

NP_062252.1

PRO

P41542

RGD

621604

Interactors (5)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O35165	4	Gosr2 [Golgi membrane] (R-RNO-6807755) Gosr2 [ER to Golgi transport vesicle membrane] (R-RNO-5689800) Gosr2 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-RNO-535472) Gosr2 [endoplasmic reticulum membrane] (R-RNO-5689451)	0.524	6
UniProt:O35152	1	Bet1l [Golgi membrane] (R-RNO-6807744)	0.524	6
UniProt:Q62931	1	Gosr1 [Golgi membrane] (R-RNO-6807753)	0.524	10
UniProt:Q08851	5	Stx5 [cytosol] (R-RNO-9613991) Stx5 [Golgi membrane] (R-RNO-6807771) Stx5 [ER to Golgi transport vesicle membrane] (R-RNO-5689838) Stx5 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-RNO-5688157) Stx5 [endoplasmic reticulum membrane] (R-RNO-5689474)	0.524	8
UniProt:Q6DFZ1	2	Gbf1 [Golgi membrane] (R-MMU-199994) Gbf1 [cytosol] (R-MMU-6807751)	0.508	3

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