Reactome | RAC1:GTP [plasma membrane]

RAC1:GTP [plasma membrane]

Stable Identifier

R-RNO-217289

Type

Complex

Species

Rattus norvegicus

Compartment

plasma membrane

Locations in the PathwayBrowser

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General

This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Participants

components

GGC-PalmC-RAC1 [plasma membrane] (Rattus norvegicus)
GTP [cytosol]

Participates

as a component of

RAC1-GTP:p-S144,T423-PAK1 [plasma membrane] (Rattus norvegicus)
RAC1:GTP:PAK1 dimer:RAC1:GTP [plasma membrane] (Rattus norvegicus)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP [plasma membrane] (Rattus norvegicus)

as an input of

PAK1 binds RAC1:GTP (Rattus norvegicus)

as an output of

KALRN exchanges GTP for GDP on RAC1, activating it (Rattus norvegicus)
p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor (Rattus norvegicus)

This entity regulates

Positively

GTP-bound RAC contributes to JNK activation (Rattus norvegicus)

Inferred From

RAC1:GTP [plasma membrane] (Homo sapiens)