H2SeO4 is converted to APSe by PAPSS1,2

Stable Identifier
R-RNO-2408504
Type
Reaction [transition]
Species
Rattus norvegicus
Compartment
cytosol
ReviewStatus
5/5
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
H2SeO4 is converted to APSe by PAPSS1,2
In rat cytosol, bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthases 1 and 2 (Papss1,2) are involved in transforming adenosine triphosphate (ATP) and selenic acid (H2SeO4) into adenylylselenate (APSe) and diphosphate via its ATP sulphurylase domain (Yu et al. 1989).
Literature References
PubMed ID Title Journal Year
2537056 Rat liver ATP-sulfurylase: purification, kinetic characterization, and interaction with arsenate, selenate, phosphate, and other inorganic oxyanions

Chen, LJ, Segel, IH, Yu, M, Martin, RL, Jain, S

Arch. Biochem. Biophys. 1989
Participants
Input
Output
Catalyst Activity

selenate adenylyltransferase (ATP) activity of Papss1,2 [cytosol]

Physical Entity
Papss1,2 [cytosol] (Rattus norvegicus)
Activity
selenate adenylyltransferase (ATP) activity (GO:0098616)
Orthologous Events
H2SeO4 is converted to APSe by PAPSS1,2 (Homo sapiens)
Authored
Williams, MG  (2014-05-06)
Reviewed
Rush, MG  (2015-08-30)
Created
Williams, MG  (2012-07-17)
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