Reactome | SARM:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane]

SARM:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane]

Stable Identifier

R-RNO-2559578

Type

Complex

Species

Rattus norvegicus

Compartment

endosome membrane

Locations in the PathwayBrowser

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General

This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Participants

components

SARM-1 [cytosol] (Rattus norvegicus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Rattus norvegicus)

Participates

as an output of

SARM binds TICAM1:TRAM:TLR4:LY96:LPS:CD14 (Rattus norvegicus)

This entity regulates

Negatively

TRAF3 binds TICAM1:activated TLR4 complex (Rattus norvegicus)
TRIF:activated TLR3/TLR4 complex recruits RIP1 (Rattus norvegicus)
Activated TLR4:TICAM1 recruits TRAF6 (Rattus norvegicus)

Inferred From

SARM:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Homo sapiens)

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