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KALRN [cytosol]
Stable Identifier
R-RNO-3006505
Type
Protein [EntityWithAccessionedSequence]
Species
Rattus norvegicus
Compartment
cytosol
Synonyms
P97924
Locations in the PathwayBrowser
Expand all
Developmental Biology (Rattus norvegicus)
Nervous system development (Rattus norvegicus)
Axon guidance (Rattus norvegicus)
EPH-Ephrin signaling (Rattus norvegicus)
EPHB-mediated forward signaling (Rattus norvegicus)
EPHB2 binds KALRN (Rattus norvegicus)
EFNBs:p-EPHBs:KALRN [plasma membrane] (Rattus norvegicus)
KALRN [cytosol] (Rattus norvegicus)
KALRN [cytosol] (Rattus norvegicus)
KALRN exchanges GTP for GDP on RAC1, activating it (Rattus norvegicus)
EFNBs:p-EPHBs:KALRN [plasma membrane] (Rattus norvegicus)
KALRN [cytosol] (Rattus norvegicus)
KALRN [cytosol] (Rattus norvegicus)
Signal Transduction (Rattus norvegicus)
Death Receptor Signaling (Rattus norvegicus)
p75 NTR receptor-mediated signalling (Rattus norvegicus)
Cell death signalling via NRAGE, NRIF and NADE (Rattus norvegicus)
NRAGE signals death through JNK (Rattus norvegicus)
p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor (Rattus norvegicus)
GEFs [cytosol] (Rattus norvegicus)
KALRN [cytosol] (Rattus norvegicus)
MAPK family signaling cascades (Rattus norvegicus)
MAPK6/MAPK4 signaling (Rattus norvegicus)
MAPKAPK5 phosphorylates KALRN (Rattus norvegicus)
KALRN:p-S189 MAPK6:p-T182 MAPKAPK5 [cytosol] (Rattus norvegicus)
KALRN [cytosol] (Rattus norvegicus)
p-S189 MAPK6:p-T182 MAPKAPK5 bind KALRN (Rattus norvegicus)
KALRN [cytosol] (Rattus norvegicus)
KALRN:p-S189 MAPK6:p-T182 MAPKAPK5 [cytosol] (Rattus norvegicus)
KALRN [cytosol] (Rattus norvegicus)
Signaling by GPCR (Rattus norvegicus)
GPCR downstream signalling (Rattus norvegicus)
G alpha (12/13) signalling events (Rattus norvegicus)
GEFs activate RhoA,B,C (Rattus norvegicus)
GEFs [cytosol] (Rattus norvegicus)
KALRN [cytosol] (Rattus norvegicus)
G alpha (q) signalling events (Rattus norvegicus)
G alpha (q) binds to Trio family RhoGEFs (Rattus norvegicus)
G-protein alpha (q/11):Trio family RhoGEFs [plasma membrane] (Rattus norvegicus)
TRIO family RhoGEFs [cytosol] (Rattus norvegicus)
KALRN [cytosol] (Rattus norvegicus)
TRIO family RhoGEFs [cytosol] (Rattus norvegicus)
KALRN [cytosol] (Rattus norvegicus)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Rattus norvegicus)
Signaling by Rho GTPases (Rattus norvegicus)
RHO GTPase cycle (Rattus norvegicus)
RAC1 GTPase cycle (Rattus norvegicus)
RAC1 GEFs activate RAC1 (Rattus norvegicus)
RAC1 GEFs [cytosol] (Rattus norvegicus)
KALRN [cytosol] (Rattus norvegicus)
RHOA GTPase cycle (Rattus norvegicus)
RHOA GEFs activate RHOA (Rattus norvegicus)
RHOA GEFs [cytosol] (Rattus norvegicus)
KALRN [cytosol] (Rattus norvegicus)
RHOG GTPase cycle (Rattus norvegicus)
RHOG GEFs activate RHOG (Rattus norvegicus)
RHOG GEFs [cytosol] (Rattus norvegicus)
KALRN [cytosol] (Rattus norvegicus)
External Reference Information
External Reference
UniProt:P97924
Reference Genes
BioGPS Gene:84009
ENSEMBL:ENSRNOG00000001706
KEGG Gene (Rattus norvegicus):84009
Monarch:84009
NCBI Gene:84009
UCSC:P97924
Reference Transcript
RefSeq:NM_032062.2
Participates
as a candidate of
RHOA GEFs [cytosol] (Rattus norvegicus)
RAC1 GEFs [cytosol] (Rattus norvegicus)
as a member of
RHOG GEFs [cytosol] (Rattus norvegicus)
TRIO family RhoGEFs [cytosol] (Rattus norvegicus)
GEFs [cytosol] (Rattus norvegicus)
as an input of
p-S189 MAPK6:p-T182 MAPKAPK5 bind KALRN (Rattus norvegicus)
EPHB2 binds KALRN (Rattus norvegicus)
as a component of
KALRN:p-S189 MAPK6:p-T182 MAPKAPK5 [cytosol] (Rattus norvegicus)
EFNBs:p-EPHBs:KALRN [plasma membrane] (Rattus norvegicus)
Other forms of this molecule
phospho-p-KALRN [cytosol]
Inferred From
KALRN [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_114451.2
IntEnz
2.7.11.1
PRO
P97924
RGD
621865
PDB
1U3O
,
5O33
,
2KR9
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P54256 HAP1
0.508
3
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