Reactome | Tcf7 [nucleoplasm]

Tcf7 [nucleoplasm]

Stable Identifier

R-RNO-3299543

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

nucleoplasm

Synonyms

TCF7, A0A8I5ZLY3

Locations in the PathwayBrowser

Expand all

Developmental Biology (Rattus norvegicus)

- MITF-M-regulated melanocyte development (Rattus norvegicus)
  - MITF-M-dependent gene expression (Rattus norvegicus)
    - Regulation of MITF-M-dependent genes involved in cell cycle and proliferation (Rattus norvegicus)
      - HINT1, HDAC1, and SIN3A bind CTNNB1 at the CCND1 promoter (Rattus norvegicus)
        
        HINT1:HDAC1:SIN3A:TCF/LEF:CTNNB1:CCND1 gene [nucleoplasm] (Rattus norvegicus)
        
        TCF/LEF:CTNNB1:CCND1 gene [nucleoplasm] (Rattus norvegicus)
        
        TCF/LEF:CTNNB1 [nucleoplasm] (Rattus norvegicus)
        
        TCF/LEF [nucleoplasm] (Rattus norvegicus)
        
        Tcf7 [nucleoplasm] (Rattus norvegicus)
        
        TCF/LEF:CTNNB1:CCND1 gene [nucleoplasm] (Rattus norvegicus)
        
        TCF/LEF:CTNNB1 [nucleoplasm] (Rattus norvegicus)
        
        TCF/LEF [nucleoplasm] (Rattus norvegicus)
        
        Tcf7 [nucleoplasm] (Rattus norvegicus)

Gene expression (Transcription) (Rattus norvegicus)

- RNA Polymerase II Transcription (Rattus norvegicus)
  - Generic Transcription Pathway (Rattus norvegicus)
    - Transcriptional regulation by RUNX3 (Rattus norvegicus)
      - RUNX3 regulates WNT signaling (Rattus norvegicus)
        
        RUNX3 binds CTNNB1:TCF7L2,(LEF1,TCF7L1,TCF7) (Rattus norvegicus)
        
        CTNNB1:TCF7L2,(LEF1,TCF7L1,TCF7) [nucleoplasm] (Rattus norvegicus)
        
        TCF7L2,(LEF1,TCF7L1,TCF7) [nucleoplasm] (Rattus norvegicus)
        
        Tcf7 [nucleoplasm] (Rattus norvegicus)
        
        RUNX3:CTNNB1:TCF7L2,(LEF1,TCF7L1,TCF7) [nucleoplasm] (Rattus norvegicus)
        
        CTNNB1:TCF7L2,(LEF1,TCF7L1,TCF7) [nucleoplasm] (Rattus norvegicus)
        
        TCF7L2,(LEF1,TCF7L1,TCF7) [nucleoplasm] (Rattus norvegicus)
        
        Tcf7 [nucleoplasm] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:A0A8I5ZLY3

Gene Names

Tcf7

Reference Genes

ENSEMBL:ENSRNOG00000005872

ENSEMBL:ENSRNOG00000005872.8 Tcf7

Reference Transcript

Other Identifiers

10742555

1376197_at

17656036

363595

5620475

5646219

5661337

5664123

5707490

5895483

5896828

5915271

5929256

5936277

6217328

6321035

6358729

6374601

6641083

6655595

AA848626_at

A_44_P497262

A_64_P103404

GE12444

GO:0000976

GO:0003677

GO:0005634

GO:0005654

GO:0008013

GO:0016055

GO:0016604

GO:0023052

GO:0043226

GO:0071353

GO:1990837

ILMN_1349990

PH_rn_0016967

PH_rn_0020737

Participates

as a member of

TCF/LEF [nucleoplasm] (Rattus norvegicus)

as a candidate of

Inferred From

TCF7 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

XP_017459546.1, XP_017453119.1

Ensembl

ENSRNOT00000118654, ENSRNOG00000005872, ENSRNOP00000078370

RGD

1305894

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