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TCF/LEF [nucleoplasm]
Stable Identifier
R-RNO-3299546
Type
Set [CandidateSet]
Species
Rattus norvegicus
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
Gene expression (Transcription) (Rattus norvegicus)
RNA Polymerase II Transcription (Rattus norvegicus)
Generic Transcription Pathway (Rattus norvegicus)
Transcriptional Regulation by VENTX (Rattus norvegicus)
VENTX disrupts binding of CTNNB1 (beta-catenin) to TCF4 or LEF1 (Rattus norvegicus)
CTNNB1:TCF7L2,LEF1:CCND1 Gene [nucleoplasm] (Rattus norvegicus)
TCF/LEF:CTNNB1 [nucleoplasm] (Rattus norvegicus)
TCF/LEF [nucleoplasm] (Rattus norvegicus)
VENTX:TCF4,LEF1:CCND1 Gene [nucleoplasm] (Rattus norvegicus)
TCF/LEF [nucleoplasm] (Rattus norvegicus)
Signal Transduction (Rattus norvegicus)
Signaling by WNT (Rattus norvegicus)
Beta-catenin independent WNT signaling (Rattus norvegicus)
Ca2+ pathway (Rattus norvegicus)
NLK phosphorylates TCF/LEF (Rattus norvegicus)
TCF/LEF:CTNNB1 [nucleoplasm] (Rattus norvegicus)
TCF/LEF [nucleoplasm] (Rattus norvegicus)
Degradation of beta-catenin by the destruction complex (Rattus norvegicus)
Repression of WNT target genes (Rattus norvegicus)
TLE tetramers bind TCF/LEF at WNT promoters (Rattus norvegicus)
'canonical' WNT target gene:TCF/LEF:TLE tetramer [nucleoplasm] (Rattus norvegicus)
'canonical' WNT target genes:TCF/LEF [nucleoplasm] (Rattus norvegicus)
TCF/LEF [nucleoplasm] (Rattus norvegicus)
'canonical' WNT target genes:TCF/LEF [nucleoplasm] (Rattus norvegicus)
TCF/LEF [nucleoplasm] (Rattus norvegicus)
TCF dependent signaling in response to WNT (Rattus norvegicus)
Deactivation of the beta-catenin transactivating complex (Rattus norvegicus)
TCF:Beta-catenin binds SOX proteins (Rattus norvegicus)
TCF/LEF:CTNNB1 [nucleoplasm] (Rattus norvegicus)
TCF/LEF [nucleoplasm] (Rattus norvegicus)
TCF/LEF:CTNNB1:SOX4,SOX13,SOX17 [nucleoplasm] (Rattus norvegicus)
TCF/LEF:CTNNB1 [nucleoplasm] (Rattus norvegicus)
TCF/LEF [nucleoplasm] (Rattus norvegicus)
beta-catenin is replaced by repression complexes at the promoter (Rattus norvegicus)
TCF/LEF:CTNNB1:APC:CTBP:BTRC [nucleoplasm] (Rattus norvegicus)
TCF/LEF [nucleoplasm] (Rattus norvegicus)
TCF/LEF:TLE:HDAC1 [nucleoplasm] (Rattus norvegicus)
TCF/LEF [nucleoplasm] (Rattus norvegicus)
Formation of the beta-catenin:TCF transactivating complex (Rattus norvegicus)
Beta-catenin displaces TLE:HDAC1 from TCF/LEF (Rattus norvegicus)
TCF/LEF:CTNNB1 [nucleoplasm] (Rattus norvegicus)
TCF/LEF [nucleoplasm] (Rattus norvegicus)
TCF/LEF:TLE:HDAC1 [nucleoplasm] (Rattus norvegicus)
TCF/LEF [nucleoplasm] (Rattus norvegicus)
Beta-catenin recruits CBP/p300 (Rattus norvegicus)
TCF/LEF:CTNNB1 [nucleoplasm] (Rattus norvegicus)
TCF/LEF [nucleoplasm] (Rattus norvegicus)
TCF/LEF:CTNNB1:CBP/p300 [nucleoplasm] (Rattus norvegicus)
TCF/LEF:CTNNB1 [nucleoplasm] (Rattus norvegicus)
TCF/LEF [nucleoplasm] (Rattus norvegicus)
Beta-catenin recruits CDC73 and LEO1 (Rattus norvegicus)
TCF/LEF:CTNNB1 [nucleoplasm] (Rattus norvegicus)
TCF/LEF [nucleoplasm] (Rattus norvegicus)
TCF/LEF:CTNNB1:PAF1-like complex [nucleoplasm] (Rattus norvegicus)
TCF/LEF:CTNNB1 [nucleoplasm] (Rattus norvegicus)
TCF/LEF [nucleoplasm] (Rattus norvegicus)
Beta-catenin recruits SMARCA4 (Rattus norvegicus)
TCF/LEF:CTNNB1 [nucleoplasm] (Rattus norvegicus)
TCF/LEF [nucleoplasm] (Rattus norvegicus)
TCF/LEF:CTNNB1:SMARCA4:TERT [nucleoplasm] (Rattus norvegicus)
TCF/LEF:CTNNB1 [nucleoplasm] (Rattus norvegicus)
TCF/LEF [nucleoplasm] (Rattus norvegicus)
Beta-catenin:TCF associates with BCL9 and PYGO (Rattus norvegicus)
TCF/LEF:CTNNB1 [nucleoplasm] (Rattus norvegicus)
TCF/LEF [nucleoplasm] (Rattus norvegicus)
TCF/LEF:CTNNB1:BCL9:PYGO [nucleoplasm] (Rattus norvegicus)
TCF/LEF [nucleoplasm] (Rattus norvegicus)
SET1 complex trimethylates H3K4 at the MYC gene (Rattus norvegicus)
TCF/LEF:CTNNB1:BCL9:PYGO:SET1-like complex [nucleoplasm] (Rattus norvegicus)
TCF/LEF [nucleoplasm] (Rattus norvegicus)
Participants
members
Tcf7l2 [nucleoplasm]
(Rattus norvegicus)
Lef1 [nucleoplasm]
(Rattus norvegicus)
candidates
Tcf7 [nucleoplasm]
(Rattus norvegicus)
Tcf7l1 [nucleoplasm]
(Rattus norvegicus)
Participates
as a component of
'canonical' WNT target genes:TCF/LEF [nucleoplasm] (Rattus norvegicus)
TCF/LEF:CTNNB1:BCL9:PYGO [nucleoplasm] (Rattus norvegicus)
TCF/LEF:CTNNB1:BCL9:PYGO:SET1-like complex [nucleoplasm] (Rattus norvegicus)
TCF/LEF:TLE:HDAC1 [nucleoplasm] (Rattus norvegicus)
TCF/LEF:CTNNB1:APC:CTBP:BTRC [nucleoplasm] (Rattus norvegicus)
VENTX:TCF4,LEF1:CCND1 Gene [nucleoplasm] (Rattus norvegicus)
TCF/LEF:CTNNB1 [nucleoplasm] (Rattus norvegicus)
Inferred From
TCF/LEF [nucleoplasm]
(Homo sapiens)
TCF7L2,LEF1 [nucleoplasm]
(Homo sapiens)
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