Reactome | Ank1 [cytosol]

Ank1 [cytosol]

Stable Identifier

R-RNO-373619

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

cytosol

Synonyms

ANK1, A0A8I5ZJ94

Locations in the PathwayBrowser

Expand all

Metabolism of proteins (Rattus norvegicus)

- Post-translational protein modification (Rattus norvegicus)
  - Asparagine N-linked glycosylation (Rattus norvegicus)
    - Transport to the Golgi and subsequent modification (Rattus norvegicus)
      - ER to Golgi Anterograde Transport (Rattus norvegicus)
        
        COPI-mediated anterograde transport (Rattus norvegicus)
        
        ARFGAP, cargo, v-SNAREs and p24 proteins bind nascent COPI complex (Rattus norvegicus)
        
        Ank1 [cytosol] (Rattus norvegicus)
        
        RAB1:GTP:GBF1:USO1:ARF:GTP:coatomer:ARFGAP1,2,3:PalmC-YKT6:p24 dimers:cargo:spectrin:ankyrin [endoplasmic reticulum-Golgi intermediate compartment membrane] (Rattus norvegicus)
        
        Ank1 [cytosol] (Rattus norvegicus)
        
        ARFGAPs stimulate ARF GTPase activity (Rattus norvegicus)
        
        RAB1:GTP:GBF1:USO1:ARF:GTP:coatomer:ARFGAP1,2,3:PalmC-YKT6:p24 dimers:cargo:spectrin:ankyrin [endoplasmic reticulum-Golgi intermediate compartment membrane] (Rattus norvegicus)
        
        Ank1 [cytosol] (Rattus norvegicus)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Rattus norvegicus)
        
        Ank1 [cytosol] (Rattus norvegicus)
        
        COPI vesicle uncoating (Rattus norvegicus)
        
        Ank1 [cytosol] (Rattus norvegicus)
        
        RAB1:GTP:USO1:coatomer:p24 dimers:cargo:spectrin:ankyrin:COG complex:GOLGA2:GORASP1:TMEM115:cis-SNARE complex [Golgi membrane] (Rattus norvegicus)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin:COG complex:GOLGA2:GORASP1:GOLGB1:TMEM115 [Golgi membrane] (Rattus norvegicus)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [Golgi membrane] (Rattus norvegicus)
        
        Ank1 [cytosol] (Rattus norvegicus)
        
        ERGIC-to-Golgi vesicles bind dynein:dynactin (Rattus norvegicus)
        
        RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Rattus norvegicus)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Rattus norvegicus)
        
        Ank1 [cytosol] (Rattus norvegicus)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Rattus norvegicus)
        
        Ank1 [cytosol] (Rattus norvegicus)
        
        Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex (Rattus norvegicus)
        
        RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Rattus norvegicus)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Rattus norvegicus)
        
        Ank1 [cytosol] (Rattus norvegicus)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin:COG complex:GOLGA2:GORASP1:GOLGB1:TMEM115 [Golgi membrane] (Rattus norvegicus)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [Golgi membrane] (Rattus norvegicus)
        
        Ank1 [cytosol] (Rattus norvegicus)
        
        cis-Golgi t-SNAREs bind YKT6 on tethered vesicle (Rattus norvegicus)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin:COG complex:GOLGA2:GORASP1:GOLGB1:TMEM115 [Golgi membrane] (Rattus norvegicus)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [Golgi membrane] (Rattus norvegicus)
        
        Ank1 [cytosol] (Rattus norvegicus)
        
        RAB1:GTP:USO1:coatomer:p24 dimers:cargo:spectrin:ankyrin:COG complex:GOLGA2:GORASP1:TMEM115:cis-SNARE complex [Golgi membrane] (Rattus norvegicus)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin:COG complex:GOLGA2:GORASP1:GOLGB1:TMEM115 [Golgi membrane] (Rattus norvegicus)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [Golgi membrane] (Rattus norvegicus)
        
        Ank1 [cytosol] (Rattus norvegicus)

Vesicle-mediated transport (Rattus norvegicus)

- Membrane Trafficking (Rattus norvegicus)
  - ER to Golgi Anterograde Transport (Rattus norvegicus)
    - COPI-mediated anterograde transport (Rattus norvegicus)
      - ARFGAP, cargo, v-SNAREs and p24 proteins bind nascent COPI complex (Rattus norvegicus)
        
        Ank1 [cytosol] (Rattus norvegicus)
        
        RAB1:GTP:GBF1:USO1:ARF:GTP:coatomer:ARFGAP1,2,3:PalmC-YKT6:p24 dimers:cargo:spectrin:ankyrin [endoplasmic reticulum-Golgi intermediate compartment membrane] (Rattus norvegicus)
        
        Ank1 [cytosol] (Rattus norvegicus)
      - ARFGAPs stimulate ARF GTPase activity (Rattus norvegicus)
        
        RAB1:GTP:GBF1:USO1:ARF:GTP:coatomer:ARFGAP1,2,3:PalmC-YKT6:p24 dimers:cargo:spectrin:ankyrin [endoplasmic reticulum-Golgi intermediate compartment membrane] (Rattus norvegicus)
        
        Ank1 [cytosol] (Rattus norvegicus)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Rattus norvegicus)
        
        Ank1 [cytosol] (Rattus norvegicus)
      - COPI vesicle uncoating (Rattus norvegicus)
        
        Ank1 [cytosol] (Rattus norvegicus)
        
        RAB1:GTP:USO1:coatomer:p24 dimers:cargo:spectrin:ankyrin:COG complex:GOLGA2:GORASP1:TMEM115:cis-SNARE complex [Golgi membrane] (Rattus norvegicus)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin:COG complex:GOLGA2:GORASP1:GOLGB1:TMEM115 [Golgi membrane] (Rattus norvegicus)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [Golgi membrane] (Rattus norvegicus)
        
        Ank1 [cytosol] (Rattus norvegicus)
      - ERGIC-to-Golgi vesicles bind dynein:dynactin (Rattus norvegicus)
        
        RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Rattus norvegicus)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Rattus norvegicus)
        
        Ank1 [cytosol] (Rattus norvegicus)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Rattus norvegicus)
        
        Ank1 [cytosol] (Rattus norvegicus)
      - Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex (Rattus norvegicus)
        
        RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Rattus norvegicus)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Rattus norvegicus)
        
        Ank1 [cytosol] (Rattus norvegicus)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin:COG complex:GOLGA2:GORASP1:GOLGB1:TMEM115 [Golgi membrane] (Rattus norvegicus)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [Golgi membrane] (Rattus norvegicus)
        
        Ank1 [cytosol] (Rattus norvegicus)
      - cis-Golgi t-SNAREs bind YKT6 on tethered vesicle (Rattus norvegicus)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin:COG complex:GOLGA2:GORASP1:GOLGB1:TMEM115 [Golgi membrane] (Rattus norvegicus)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [Golgi membrane] (Rattus norvegicus)
        
        Ank1 [cytosol] (Rattus norvegicus)
        
        RAB1:GTP:USO1:coatomer:p24 dimers:cargo:spectrin:ankyrin:COG complex:GOLGA2:GORASP1:TMEM115:cis-SNARE complex [Golgi membrane] (Rattus norvegicus)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin:COG complex:GOLGA2:GORASP1:GOLGB1:TMEM115 [Golgi membrane] (Rattus norvegicus)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [Golgi membrane] (Rattus norvegicus)
        
        Ank1 [cytosol] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:A0A8I5ZJ94

Gene Names

Ank1

Reference Genes

ENSEMBL:ENSRNOG00000018241

ENSEMBL:ENSRNOG00000018241.7 Ank1

Other Identifiers

10792354

1389398_at

1397805_at

17712445

306570

5630018

5634044

5683060

5686529

5750008

5752062

5807994

5817944

5883319

5970372

5989611

6037673

6074116

6079465

6110782

6142046

6204327

6219295

6259659

6267520

6271297

6289302

6329548

6346929

6349020

6358066

6379478

6389926

6458944

6467062

6498597

6505683

6509277

6515589

6578727

6609054

6613087

6626512

6627179

6629214

6630122

6636866

6641871

6678095

6695055

6728238

6730508

6736540

GE1103406

GE1166431

GO:0005515

GO:0005856

GO:0005886

GO:0006888

GO:0007165

GO:0008092

GO:0008093

GO:0009898

GO:0014731

GO:0016192

GO:0019899

GO:0019903

GO:0023052

GO:0030507

GO:0043226

GO:0051117

GO:0060090

GO:0072659

GO:0170014

ILMN_1348865

PH_rn_0019982

rc_AI137502_at

Participates

as a component of

as an output of

COPI vesicle uncoating (Rattus norvegicus)

as an input of

ARFGAP, cargo, v-SNAREs and p24 proteins bind nascent COPI complex (Rattus norvegicus)

Inferred From

ANK1-3 [cytosol] (Homo sapiens)

Ankyrin [cytosol] (Homo sapiens)

ANK1 [cytosol] (Homo sapiens)

Cross References

Ensembl

ENSRNOG00000018241, ENSRNOT00000102914, ENSRNOP00000076708

RGD

1309620

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