Reactome | Ackr3 [plasma membrane]

Ackr3 [plasma membrane]

Stable Identifier

R-RNO-373859

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

plasma membrane

Synonyms

CXCR7, O89039

Locations in the PathwayBrowser

Expand all

Signal Transduction (Rattus norvegicus)

- Signaling by GPCR (Rattus norvegicus)
  - GPCR downstream signalling (Rattus norvegicus)
    - G alpha (i) signalling events (Rattus norvegicus)
      - Liganded Gi-activating GPCR acts as a GEF for Gi (Rattus norvegicus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Rattus norvegicus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Rattus norvegicus)
        
        CXCR4,7:CXCL12 [plasma membrane] (Rattus norvegicus)
        
        CXCR4,7 [plasma membrane] (Rattus norvegicus)
        
        Ackr3 [plasma membrane] (Rattus norvegicus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Rattus norvegicus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Rattus norvegicus)
        
        CXCR4,7:CXCL12 [plasma membrane] (Rattus norvegicus)
        
        CXCR4,7 [plasma membrane] (Rattus norvegicus)
        
        Ackr3 [plasma membrane] (Rattus norvegicus)
  - GPCR ligand binding (Rattus norvegicus)
    - Class A/1 (Rhodopsin-like receptors) (Rattus norvegicus)
      - Peptide ligand-binding receptors (Rattus norvegicus)
        
        Chemokine receptors bind chemokines (Rattus norvegicus)
        
        Receptors CXCR4 and 7 bind CXCL12 ligand (Rattus norvegicus)
        
        CXCR4,7 [plasma membrane] (Rattus norvegicus)
        
        Ackr3 [plasma membrane] (Rattus norvegicus)
        
        CXCR4,7:CXCL12 [plasma membrane] (Rattus norvegicus)
        
        CXCR4,7 [plasma membrane] (Rattus norvegicus)
        
        Ackr3 [plasma membrane] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:O89039

Gene Names

Ackr3

Reference Genes

BioGPS Gene:84348 Ackr3

ENSEMBL:ENSRNOG00000019622

ENSEMBL:ENSRNOG00000019622.4 Ackr3

ENSEMBL:ENSRNOG00055010155

ENSEMBL:ENSRNOG00060010605

ENSEMBL:ENSRNOG00065019894

KEGG Gene (Rattus norvegicus):84348 Ackr3

Monarch:84348 Ackr3

NCBI Gene:84348 Ackr3

UCSC:O89039 Ackr3

Reference Transcript

Other Identifiers

10925291

1367940_at

17861494

5665112

5717884

5816449

5890871

5932298

5954892

6073317

6134622

6135266

6166082

6190906

6294645

6489533

6578372

6716727

6719771

84348

AJ010828_at

A_44_P252483

GE1126478

GE21430

GO:0001525

GO:0001570

GO:0004930

GO:0005044

GO:0005768

GO:0005886

GO:0005905

GO:0006935

GO:0007186

GO:0008285

GO:0009986

GO:0012501

GO:0015026

GO:0016020

GO:0016192

GO:0016494

GO:0019956

GO:0019958

GO:0021557

GO:0023052

GO:0030154

GO:0031410

GO:0031623

GO:0038024

GO:0043226

GO:0043231

GO:0048856

GO:0060089

GO:0070098

GO:0070374

GO:1902230

rc_AA997721_s_at

Participates

as a member of

CXCR4,7 [plasma membrane] (Rattus norvegicus)

Inferred From

CXCR7 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

XP_006245541.1, NP_445804.1

Ensembl

ENSRNOP00000091223, ENSRNOT00000098919, ENSRNOG00000019622, ENSRNOP00000086994, ENSRNOP00000088201, ENSRNOT00000113813, ENSRNOT00000108608, ENSRNOP00000026558, ENSRNOT00000116518, ENSRNOP00000083985, ENSRNOT00000115723, ENSRNOT00000026558, ENSRNOP00000094961

PRO

O89039

RGD

620601