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p-S133-Creb1 [nucleoplasm]
Stable Identifier
R-RNO-379806
Type
Genes and Transcripts [EntityWithAccessionedSequence]
Species
Rattus norvegicus
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
Developmental Biology (Rattus norvegicus)
Nervous system development (Rattus norvegicus)
Axon guidance (Rattus norvegicus)
NCAM signaling for neurite out-growth (Rattus norvegicus)
MSK1 activates CREB (Rattus norvegicus)
p-S133-Creb1 [nucleoplasm] (Rattus norvegicus)
Immune System (Rattus norvegicus)
Cytokine Signaling in Immune system (Rattus norvegicus)
Signaling by Interleukins (Rattus norvegicus)
Interleukin-17 signaling (Rattus norvegicus)
MAP kinase activation (Rattus norvegicus)
MAPK targets/ Nuclear events mediated by MAP kinases (Rattus norvegicus)
CREB phosphorylation (Rattus norvegicus)
MAPKAPK2 phosphorylates CREB at Serine 133 (Rattus norvegicus)
p-S133-Creb1 [nucleoplasm] (Rattus norvegicus)
MSK1 activates CREB (Rattus norvegicus)
p-S133-Creb1 [nucleoplasm] (Rattus norvegicus)
RSK1/2/3 phosphorylates CREB at Serine 119 (Rattus norvegicus)
p-S133-Creb1 [nucleoplasm] (Rattus norvegicus)
Innate Immune System (Rattus norvegicus)
Toll-like Receptor Cascades (Rattus norvegicus)
Toll Like Receptor 10 (TLR10) Cascade (Rattus norvegicus)
MyD88 cascade initiated on plasma membrane (Rattus norvegicus)
MAP kinase activation (Rattus norvegicus)
MAPK targets/ Nuclear events mediated by MAP kinases (Rattus norvegicus)
CREB phosphorylation (Rattus norvegicus)
MAPKAPK2 phosphorylates CREB at Serine 133 (Rattus norvegicus)
p-S133-Creb1 [nucleoplasm] (Rattus norvegicus)
MSK1 activates CREB (Rattus norvegicus)
p-S133-Creb1 [nucleoplasm] (Rattus norvegicus)
RSK1/2/3 phosphorylates CREB at Serine 119 (Rattus norvegicus)
p-S133-Creb1 [nucleoplasm] (Rattus norvegicus)
Toll Like Receptor 2 (TLR2) Cascade (Rattus norvegicus)
Toll Like Receptor TLR1:TLR2 Cascade (Rattus norvegicus)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Rattus norvegicus)
MAP kinase activation (Rattus norvegicus)
MAPK targets/ Nuclear events mediated by MAP kinases (Rattus norvegicus)
CREB phosphorylation (Rattus norvegicus)
MAPKAPK2 phosphorylates CREB at Serine 133 (Rattus norvegicus)
p-S133-Creb1 [nucleoplasm] (Rattus norvegicus)
MSK1 activates CREB (Rattus norvegicus)
p-S133-Creb1 [nucleoplasm] (Rattus norvegicus)
RSK1/2/3 phosphorylates CREB at Serine 119 (Rattus norvegicus)
p-S133-Creb1 [nucleoplasm] (Rattus norvegicus)
Toll Like Receptor TLR6:TLR2 Cascade (Rattus norvegicus)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Rattus norvegicus)
MAP kinase activation (Rattus norvegicus)
MAPK targets/ Nuclear events mediated by MAP kinases (Rattus norvegicus)
CREB phosphorylation (Rattus norvegicus)
MAPKAPK2 phosphorylates CREB at Serine 133 (Rattus norvegicus)
p-S133-Creb1 [nucleoplasm] (Rattus norvegicus)
MSK1 activates CREB (Rattus norvegicus)
p-S133-Creb1 [nucleoplasm] (Rattus norvegicus)
RSK1/2/3 phosphorylates CREB at Serine 119 (Rattus norvegicus)
p-S133-Creb1 [nucleoplasm] (Rattus norvegicus)
Toll Like Receptor 3 (TLR3) Cascade (Rattus norvegicus)
MAP kinase activation (Rattus norvegicus)
MAPK targets/ Nuclear events mediated by MAP kinases (Rattus norvegicus)
CREB phosphorylation (Rattus norvegicus)
MAPKAPK2 phosphorylates CREB at Serine 133 (Rattus norvegicus)
p-S133-Creb1 [nucleoplasm] (Rattus norvegicus)
MSK1 activates CREB (Rattus norvegicus)
p-S133-Creb1 [nucleoplasm] (Rattus norvegicus)
RSK1/2/3 phosphorylates CREB at Serine 119 (Rattus norvegicus)
p-S133-Creb1 [nucleoplasm] (Rattus norvegicus)
Toll Like Receptor 4 (TLR4) Cascade (Rattus norvegicus)
MyD88-independent TLR4 cascade (Rattus norvegicus)
TRIF (TICAM1)-mediated TLR4 signaling (Rattus norvegicus)
MAP kinase activation (Rattus norvegicus)
MAPK targets/ Nuclear events mediated by MAP kinases (Rattus norvegicus)
CREB phosphorylation (Rattus norvegicus)
MAPKAPK2 phosphorylates CREB at Serine 133 (Rattus norvegicus)
p-S133-Creb1 [nucleoplasm] (Rattus norvegicus)
MSK1 activates CREB (Rattus norvegicus)
p-S133-Creb1 [nucleoplasm] (Rattus norvegicus)
RSK1/2/3 phosphorylates CREB at Serine 119 (Rattus norvegicus)
p-S133-Creb1 [nucleoplasm] (Rattus norvegicus)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Rattus norvegicus)
MAP kinase activation (Rattus norvegicus)
MAPK targets/ Nuclear events mediated by MAP kinases (Rattus norvegicus)
CREB phosphorylation (Rattus norvegicus)
MAPKAPK2 phosphorylates CREB at Serine 133 (Rattus norvegicus)
p-S133-Creb1 [nucleoplasm] (Rattus norvegicus)
MSK1 activates CREB (Rattus norvegicus)
p-S133-Creb1 [nucleoplasm] (Rattus norvegicus)
RSK1/2/3 phosphorylates CREB at Serine 119 (Rattus norvegicus)
p-S133-Creb1 [nucleoplasm] (Rattus norvegicus)
Toll Like Receptor 5 (TLR5) Cascade (Rattus norvegicus)
MyD88 cascade initiated on plasma membrane (Rattus norvegicus)
MAP kinase activation (Rattus norvegicus)
MAPK targets/ Nuclear events mediated by MAP kinases (Rattus norvegicus)
CREB phosphorylation (Rattus norvegicus)
MAPKAPK2 phosphorylates CREB at Serine 133 (Rattus norvegicus)
p-S133-Creb1 [nucleoplasm] (Rattus norvegicus)
MSK1 activates CREB (Rattus norvegicus)
p-S133-Creb1 [nucleoplasm] (Rattus norvegicus)
RSK1/2/3 phosphorylates CREB at Serine 119 (Rattus norvegicus)
p-S133-Creb1 [nucleoplasm] (Rattus norvegicus)
Toll Like Receptor 7/8 (TLR7/8) Cascade (Rattus norvegicus)
MyD88 dependent cascade initiated on endosome (Rattus norvegicus)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Rattus norvegicus)
MAP kinase activation (Rattus norvegicus)
MAPK targets/ Nuclear events mediated by MAP kinases (Rattus norvegicus)
CREB phosphorylation (Rattus norvegicus)
MAPKAPK2 phosphorylates CREB at Serine 133 (Rattus norvegicus)
p-S133-Creb1 [nucleoplasm] (Rattus norvegicus)
MSK1 activates CREB (Rattus norvegicus)
p-S133-Creb1 [nucleoplasm] (Rattus norvegicus)
RSK1/2/3 phosphorylates CREB at Serine 119 (Rattus norvegicus)
p-S133-Creb1 [nucleoplasm] (Rattus norvegicus)
Toll Like Receptor 9 (TLR9) Cascade (Rattus norvegicus)
MyD88 dependent cascade initiated on endosome (Rattus norvegicus)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Rattus norvegicus)
MAP kinase activation (Rattus norvegicus)
MAPK targets/ Nuclear events mediated by MAP kinases (Rattus norvegicus)
CREB phosphorylation (Rattus norvegicus)
MAPKAPK2 phosphorylates CREB at Serine 133 (Rattus norvegicus)
p-S133-Creb1 [nucleoplasm] (Rattus norvegicus)
MSK1 activates CREB (Rattus norvegicus)
p-S133-Creb1 [nucleoplasm] (Rattus norvegicus)
RSK1/2/3 phosphorylates CREB at Serine 119 (Rattus norvegicus)
p-S133-Creb1 [nucleoplasm] (Rattus norvegicus)
Neuronal System (Rattus norvegicus)
Transmission across Chemical Synapses (Rattus norvegicus)
Neurotransmitter receptors and postsynaptic signal transmission (Rattus norvegicus)
Activation of NMDA receptors and postsynaptic events (Rattus norvegicus)
Post NMDA receptor activation events (Rattus norvegicus)
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling (Rattus norvegicus)
Phosphorylation of CREB1 by ribosomal protein S6 kinases (RSKs) (Rattus norvegicus)
p-S133-Creb1 [nucleoplasm] (Rattus norvegicus)
Signal Transduction (Rattus norvegicus)
Intracellular signaling by second messengers (Rattus norvegicus)
PIP3 activates AKT signaling (Rattus norvegicus)
AKT phosphorylates targets in the nucleus (Rattus norvegicus)
AKT phosphorylates CREB1 (Rattus norvegicus)
p-S133-Creb1 [nucleoplasm] (Rattus norvegicus)
Signaling by GPCR (Rattus norvegicus)
GPCR downstream signalling (Rattus norvegicus)
G alpha (q) signalling events (Rattus norvegicus)
Gastrin-CREB signalling pathway via PKC and MAPK (Rattus norvegicus)
RSK1/2/3 phosphorylates CREB at Serine 119 (Rattus norvegicus)
p-S133-Creb1 [nucleoplasm] (Rattus norvegicus)
Signaling by Nuclear Receptors (Rattus norvegicus)
ESR-mediated signaling (Rattus norvegicus)
Extra-nuclear estrogen signaling (Rattus norvegicus)
Estrogen-dependent nuclear events downstream of ESR-membrane signaling (Rattus norvegicus)
AKT phosphorylates CREB1 (Rattus norvegicus)
p-S133-Creb1 [nucleoplasm] (Rattus norvegicus)
Signaling by Receptor Tyrosine Kinases (Rattus norvegicus)
Signaling by NTRKs (Rattus norvegicus)
Signaling by NTRK1 (TRKA) (Rattus norvegicus)
Nuclear Events (kinase and transcription factor activation) (Rattus norvegicus)
CREB phosphorylation (Rattus norvegicus)
MAPKAPK2 phosphorylates CREB at Serine 133 (Rattus norvegicus)
p-S133-Creb1 [nucleoplasm] (Rattus norvegicus)
MSK1 activates CREB (Rattus norvegicus)
p-S133-Creb1 [nucleoplasm] (Rattus norvegicus)
RSK1/2/3 phosphorylates CREB at Serine 119 (Rattus norvegicus)
p-S133-Creb1 [nucleoplasm] (Rattus norvegicus)
NGF-stimulated transcription (Rattus norvegicus)
SGK phosphorylates CREB1 (Rattus norvegicus)
p-S133-Creb1 [nucleoplasm] (Rattus norvegicus)
External Reference Information
External Reference
UniProt:P15337-1 Creb1
Gene Names
Creb1, Creb-1
Other Identifiers
10803671
10923929
10923938
1369708_a_at
1375655_at
1382633_at
1383383_at
17859930
17859940
5720214
5823009
5862978
5878105
5898581
6025062
6079971
6087092
6091129
6175444
6226642
6273037
6302829
6429262
6445658
6572700
6581577
6619433
6670066
81646
A_44_P177425
A_44_P392701
A_44_P491590
A_44_P554741
A_44_P568560
A_44_P690321
A_44_P742369
A_64_P112246
GE1228833
GE1255448
GE1258161
GE1272122
GE17391
GE22111
GO:0003677
GO:0003700
GO:0005515
GO:0005634
GO:0006355
GO:0043226
GO:0140110
ILMN_1376791
ILMN_1649829
PH_rn_0012052
PH_rn_0023688
X14788_s_at
rc_AA799601_at
rc_AI175012_at
Participates
as a component of
Vgf gene:p-S133-Creb:Tcf12:Ascl1:p300 [nucleoplasm] (Rattus norvegicus)
p-S133-Creb1 homodimer [nucleoplasm] (Rattus norvegicus)
as an input of
p-Creb, Ascl1, Tcf12, p300 bind the vgf promoter (Rattus norvegicus)
Dimerization of p-S133-Creb1 (Rattus norvegicus)
as an output of
MAPKAPK2 phosphorylates CREB at Serine 133 (Rattus norvegicus)
RSK1/2/3 phosphorylates CREB at Serine 119 (Rattus norvegicus)
Prkaca phosphorylates Creb1 (Rattus norvegicus)
MSK1 activates CREB (Rattus norvegicus)
SGK phosphorylates CREB1 (Rattus norvegicus)
Phosphorylation of CREB1 by ribosomal protein S6 kinases (RSKs) (Rattus norvegicus)
AKT phosphorylates CREB1 (Rattus norvegicus)
CaMKIV phosphorylates Creb1 (Rattus norvegicus)
Other forms of this molecule
Creb1 [nucleoplasm]
Inferred From
p-S133-CREB1 [nucleoplasm]
(Homo sapiens)
Modified Residues
Name
O-phospho-L-serine at 133
Coordinate
133
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Cross References
RefSeq
XP_006245127.1
,
XP_006245128.1
,
NP_112279.1
,
NP_604392.1
,
XP_038940173.1
,
NP_604392.2
ENSEMBL
ENSRNOG00000013412
,
ENSRNOT00000018326
,
ENSRNOP00000018326
PRO
P15337
GlyGen
P15337
RGD
620218
PDB
1KDX
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