Reactome | Pcnt [cytosol]

Pcnt [cytosol]

Stable Identifier

R-RNO-380290

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

cytosol

Synonyms

PCNT, D3ZMY8

Locations in the PathwayBrowser

Expand all

Organelle biogenesis and maintenance (Rattus norvegicus)

- Cilium Assembly (Rattus norvegicus)
  - Anchoring of the basal body to the plasma membrane (Rattus norvegicus)
    - C2CD3 and OFD1 recruit 5 distal appendage proteins to the centriole (Rattus norvegicus)
      - Centrosome:C2CD3:distal appendage proteins [cytosol] (Rattus norvegicus)
        
        mother centriole:C2CD3 [cytosol] (Rattus norvegicus)
        
        mother centriole [cytosol] (Rattus norvegicus)
        
        Pcnt [cytosol] (Rattus norvegicus)
      - mother centriole:C2CD3 [cytosol] (Rattus norvegicus)
        
        mother centriole [cytosol] (Rattus norvegicus)
        
        Pcnt [cytosol] (Rattus norvegicus)
    - C2CD3 binds the mother centriole (Rattus norvegicus)
      - mother centriole [cytosol] (Rattus norvegicus)
        
        Pcnt [cytosol] (Rattus norvegicus)
      - mother centriole:C2CD3 [cytosol] (Rattus norvegicus)
        
        mother centriole [cytosol] (Rattus norvegicus)
        
        Pcnt [cytosol] (Rattus norvegicus)
    - CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body (Rattus norvegicus)
      - basal body:transition zone proteins [cytosol] (Rattus norvegicus)
        
        basal body [cytosol] (Rattus norvegicus)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Rattus norvegicus)
        
        Pcnt [cytosol] (Rattus norvegicus)
      - basal body:transition zone proteins:RAB3IP:RAB11A:GTP:Golgi-derived vesicle [cytosol] (Rattus norvegicus)
        
        basal body:transition zone proteins [cytosol] (Rattus norvegicus)
        
        basal body [cytosol] (Rattus norvegicus)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Rattus norvegicus)
        
        Pcnt [cytosol] (Rattus norvegicus)
    - CP110 and CEP97 dissociate from the centriole (Rattus norvegicus)
      - basal body [cytosol] (Rattus norvegicus)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Rattus norvegicus)
        
        Pcnt [cytosol] (Rattus norvegicus)
      - centrosome:C2CD2:distal appendage proteins:TTBK2:MARK4 [cytosol] (Rattus norvegicus)
        
        Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Rattus norvegicus)
        
        Centrosome:C2CD3:distal appendage proteins [cytosol] (Rattus norvegicus)
        
        mother centriole:C2CD3 [cytosol] (Rattus norvegicus)
        
        mother centriole [cytosol] (Rattus norvegicus)
        
        Pcnt [cytosol] (Rattus norvegicus)
    - MARK4 binds ODF2 in the centriole (Rattus norvegicus)
      - Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Rattus norvegicus)
        
        Centrosome:C2CD3:distal appendage proteins [cytosol] (Rattus norvegicus)
        
        mother centriole:C2CD3 [cytosol] (Rattus norvegicus)
        
        mother centriole [cytosol] (Rattus norvegicus)
        
        Pcnt [cytosol] (Rattus norvegicus)
      - centrosome:C2CD2:distal appendage proteins:TTBK2:MARK4 [cytosol] (Rattus norvegicus)
        
        Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Rattus norvegicus)
        
        Centrosome:C2CD3:distal appendage proteins [cytosol] (Rattus norvegicus)
        
        mother centriole:C2CD3 [cytosol] (Rattus norvegicus)
        
        mother centriole [cytosol] (Rattus norvegicus)
        
        Pcnt [cytosol] (Rattus norvegicus)
    - RAB3IP stimulates nucleotide exchange on RAB8A (Rattus norvegicus)
      - basal body:transition zone proteins:RAB3IP:RAB11A:GTP:Golgi-derived vesicle [cytosol] (Rattus norvegicus)
        
        basal body:transition zone proteins [cytosol] (Rattus norvegicus)
        
        basal body [cytosol] (Rattus norvegicus)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Rattus norvegicus)
        
        Pcnt [cytosol] (Rattus norvegicus)
    - Recruitment of transition zone proteins (Rattus norvegicus)
      - basal body [cytosol] (Rattus norvegicus)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Rattus norvegicus)
        
        Pcnt [cytosol] (Rattus norvegicus)
      - basal body:transition zone proteins [cytosol] (Rattus norvegicus)
        
        basal body [cytosol] (Rattus norvegicus)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Rattus norvegicus)
        
        Pcnt [cytosol] (Rattus norvegicus)
    - The distal appendage proteins recruit TTBK2 (Rattus norvegicus)
      - Centrosome:C2CD3:distal appendage proteins [cytosol] (Rattus norvegicus)
        
        mother centriole:C2CD3 [cytosol] (Rattus norvegicus)
        
        mother centriole [cytosol] (Rattus norvegicus)
        
        Pcnt [cytosol] (Rattus norvegicus)
      - Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Rattus norvegicus)
        
        Centrosome:C2CD3:distal appendage proteins [cytosol] (Rattus norvegicus)
        
        mother centriole:C2CD3 [cytosol] (Rattus norvegicus)
        
        mother centriole [cytosol] (Rattus norvegicus)
        
        Pcnt [cytosol] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:D3ZMY8

Gene Names

Pcnt

Reference Genes

ENSEMBL:ENSRNOG00000001276

UCSC:D3ZMY8 Pcnt

Other Identifiers

1373930_at

17754429

309692

5620642

5626397

5660501

5755037

5795490

5798794

5801165

5827015

5830099

5877687

5905606

5932541

5937253

5937692

5956784

6004464

6010390

6018330

6081412

6091352

6102644

6102906

6126093

6141608

6158351

6162804

6205490

6225465

6227652

6238564

6241019

6269154

6291430

6323382

6326234

6408169

6410656

6412850

6416059

6497673

6525436

6536519

6564630

6588271

6601341

6680129

6682817

6704065

6709102

A_44_P262804

A_44_P529986

GE1230251

GE12974

GO:0000226

GO:0000278

GO:0005813

GO:0005814

GO:0005815

GO:0005829

GO:0005856

GO:0006886

GO:0007010

GO:0007052

GO:0007165

GO:0023052

GO:0034451

GO:0043226

GO:0044782

GO:0060090

GO:0060271

GO:0090316

PH_rn_0020443

rc_AA996578_at

Participates

as a component of

as a member of

Misfolded cilia proteins [cytosol] (Rattus norvegicus)

Other forms of this molecule

Pcnt [cytosol]

Inferred From

PCNT [cytosol] (Homo sapiens)

Misfolded PCNT [cytosol] (Homo sapiens)

Cross References

ENSEMBL

ENSRNOP00000039329, ENSRNOT00000048218, ENSRNOG00000001276

RGD

1595865

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