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CRK, CRKL [cytosol]
Stable Identifier
R-RNO-381945
Type
Set [DefinedSet]
Species
Rattus norvegicus
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Immune System (Rattus norvegicus)
Cytokine Signaling in Immune system (Rattus norvegicus)
Signaling by Interleukins (Rattus norvegicus)
Interleukin-3, Interleukin-5 and GM-CSF signaling (Rattus norvegicus)
Regulation of signaling by CBL (Rattus norvegicus)
CBL binds CRK (Rattus norvegicus)
CRK, CRKL [cytosol] (Rattus norvegicus)
p(Y700,731,774)-CBL:CRK [cytosol] (Rattus norvegicus)
CRK, CRKL [cytosol] (Rattus norvegicus)
CBL:CRKL binds RAPGEF1 (Rattus norvegicus)
p(Y700,731,774)-CBL:CRK [cytosol] (Rattus norvegicus)
CRK, CRKL [cytosol] (Rattus norvegicus)
p(Y700,731,774)-CBL:CRK:RAPGEF1 [cytosol] (Rattus norvegicus)
p(Y700,731,774)-CBL:CRK [cytosol] (Rattus norvegicus)
CRK, CRKL [cytosol] (Rattus norvegicus)
Signal Transduction (Rattus norvegicus)
Signaling by Receptor Tyrosine Kinases (Rattus norvegicus)
Signaling by MET (Rattus norvegicus)
MET promotes cell motility (Rattus norvegicus)
MET activates RAP1 and RAC1 (Rattus norvegicus)
CRK,CRKL recruits RAC1 GEF to activated MET (Rattus norvegicus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL [plasma membrane] (Rattus norvegicus)
CRK, CRKL [cytosol] (Rattus norvegicus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL:(DOCK7) [plasma membrane] (Rattus norvegicus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL [plasma membrane] (Rattus norvegicus)
CRK, CRKL [cytosol] (Rattus norvegicus)
DOCK7 activates RAC1 (Rattus norvegicus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL:(DOCK7) [plasma membrane] (Rattus norvegicus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL [plasma membrane] (Rattus norvegicus)
CRK, CRKL [cytosol] (Rattus norvegicus)
GAB1 recruits CRK,CRKL to MET (Rattus norvegicus)
CRK, CRKL [cytosol] (Rattus norvegicus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL [plasma membrane] (Rattus norvegicus)
CRK, CRKL [cytosol] (Rattus norvegicus)
RAPGEF1 activates RAP1 (Rattus norvegicus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL:RAPGEF1 [plasma membrane] (Rattus norvegicus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL [plasma membrane] (Rattus norvegicus)
CRK, CRKL [cytosol] (Rattus norvegicus)
RAPGEF1 binds CRK,CRKL (Rattus norvegicus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL [plasma membrane] (Rattus norvegicus)
CRK, CRKL [cytosol] (Rattus norvegicus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL:RAPGEF1 [plasma membrane] (Rattus norvegicus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL [plasma membrane] (Rattus norvegicus)
CRK, CRKL [cytosol] (Rattus norvegicus)
MET receptor recycling (Rattus norvegicus)
GGA3 associates with activated MET receptor (Rattus norvegicus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL [plasma membrane] (Rattus norvegicus)
CRK, CRKL [cytosol] (Rattus norvegicus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL:GGA3:ARF6:GTP [recycling endosome membrane] (Rattus norvegicus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL [plasma membrane] (Rattus norvegicus)
CRK, CRKL [cytosol] (Rattus norvegicus)
RAB4:GTP promotes recycling of activated MET receptor to the plasma membrane (Rattus norvegicus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL:GGA3:ARF6:GTP [recycling endosome membrane] (Rattus norvegicus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL [plasma membrane] (Rattus norvegicus)
CRK, CRKL [cytosol] (Rattus norvegicus)
Signaling by PDGF (Rattus norvegicus)
Downstream signal transduction (Rattus norvegicus)
Crk binds to the active PDGF receptor (Rattus norvegicus)
CRK, CRKL [cytosol] (Rattus norvegicus)
PDGF:Phospho-PDGF receptor dimer:Crk [plasma membrane] (Rattus norvegicus)
CRK, CRKL [cytosol] (Rattus norvegicus)
p130Cas and C3G bind PDGFR bound Crk (Rattus norvegicus)
PDGF:Phospho-PDGF receptor dimer:Crk [plasma membrane] (Rattus norvegicus)
CRK, CRKL [cytosol] (Rattus norvegicus)
PDGF:Phospho-PDGF receptor dimer:Crk:p130Cas:C3G [plasma membrane] (Rattus norvegicus)
PDGF:Phospho-PDGF receptor dimer:Crk [plasma membrane] (Rattus norvegicus)
CRK, CRKL [cytosol] (Rattus norvegicus)
Participants
members
Crkl [cytosol]
(Rattus norvegicus)
Crk [cytosol]
(Rattus norvegicus)
Participates
as an input of
CBL binds CRK (Rattus norvegicus)
GAB1 recruits CRK,CRKL to MET (Rattus norvegicus)
Crk binds to the active PDGF receptor (Rattus norvegicus)
as a component of
p(Y700,731,774)-CBL:CRK [cytosol] (Rattus norvegicus)
HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL [plasma membrane] (Rattus norvegicus)
PDGF:Phospho-PDGF receptor dimer:Crk [plasma membrane] (Rattus norvegicus)
Inferred From
CRK, CRKL [cytosol]
(Homo sapiens)
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